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Walter N. Hittelman
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Journal Articles

Abstract PR08: Inhibition of ATR as a therapeutic strategy to overcome cisplatin resistance in HNSCC

Antje Lindemann, Hideaki Takahashi, Ameeta A. Patel, Walter N. Hittelman, Abdullah A. Osman, Jeffrey N. Myers
Journal: Clinical Cancer Research
Clin Cancer Res (2020) 26 (12_Supplement_2): PR08.
DOI: https://doi.org/10.1158/1557-3265.AACRAHNS19-PR08
Published: 15 June 2020
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COTI-2, A Novel Thiosemicarbazone Derivative, Exhibits Antitumor Activity in HNSCC through p53-dependent and -independent Mechanisms

Antje Lindemann, Ameeta A. Patel, Natalie L. Silver, Lin Tang, Zhiyi Liu, Li Wang, Noriaki Tanaka, Xiayu Rao, Hideaki Takahashi, Nakachi K. Maduka, Mei Zhao, Tseng-Cheng Chen, WeiWei Liu, Meng Gao, Jing Wang, Steven J. Frank, Walter N. Hittelman, Gordon B. Mills, Jeffrey N. Myers, Abdullah A. Osman
Journal: Clinical Cancer Research
Series: Author Choice
Clin Cancer Res (2019) 25 (18): 5650–5662.
DOI: https://doi.org/10.1158/1078-0432.CCR-19-0096
Published: 13 September 2019
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Journal Articles

Abstract 44: Synergistic antitumor activity of olaparib combined with AZD1775 in head and neck squamous cell carcinoma

Hideaki Takahashi, Antje Lindemann, Ameeta A. Patel, Weiwei Liu, Noriaki Tanaka, Lin Tang, Mei Zhao, Walter N. Hittelman, Jeffrey N. Myers, Abdullah A. Osman
Journal: Clinical Cancer Research
Clin Cancer Res (2017) 23 (23_Supplement): 44.
DOI: https://doi.org/10.1158/1557-3265.AACRAHNS17-44
Published: 30 November 2017
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Replication Stress Leading to Apoptosis within the S-phase Contributes to Synergism between Vorinostat and AZD1775 in HNSCC Harboring High-Risk TP53 Mutation

Noriaki Tanaka, Ameeta A. Patel, Lin Tang, Natalie L. Silver, Antje Lindemann, Hideaki Takahashi, Roman Jaksik, Xiayu Rao, Nene N. Kalu, Tseng-Cheng Chen, Jiping Wang, Mitchell J. Frederick, Faye Johnson, Frederico O. Gleber-Netto, Siqing Fu, Marek Kimmel, Jing Wang, Walter N. Hittelman, Curtis R. Pickering, Jeffrey N. Myers, Abdullah A. Osman
Journal: Clinical Cancer Research
Series: Author Choice
Clin Cancer Res (2017) 23 (21): 6541–6554.
DOI: https://doi.org/10.1158/1078-0432.CCR-17-0947
Published: 31 October 2017
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Includes: Multimedia, Supplementary data
Journal Articles

Fenretinide Activity in Retinoid-Resistant Oral Leukoplakia

Scott M. Lippman, J. Jack Lee, Jack W. Martin, Adel K. El-Naggar, Xiaochun Xu, Dong M. Shin, Margaret Thomas, Li Mao, Herbert A. Fritsche, Jr., Xian Zhou, Vassiliki Papadimitrakopoulou, Fadlo R. Khuri, Hai Tran, Gary L. Clayman, Walter N. Hittelman, Waun Ki Hong, Reuben Lotan
Journal: Clinical Cancer Research
Clin Cancer Res (2006) 12 (10): 3109–3114.
DOI: https://doi.org/10.1158/1078-0432.CCR-05-2636
Published: 17 May 2006
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Phase II Clinical Trial of N -(4-Hydroxyphenyl)retinamide and Tamoxifen Administration before Definitive Surgery for Breast Neoplasia

S. Eva Singletary, Edward N. Atkinson, Ashraful Hoque, Nour Sneige, Ayse A. Sahin, Herbert A. Fritsche, Jr., Reuben Lotan, Tao Lu, Walter N. Hittelman, Therese B. Bevers, Carol B. Stelling, Scott M. Lippman
Journal: Clinical Cancer Research
Clin Cancer Res (2002) 8 (9): 2835–2842.
Published: 01 September 2002
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A Randomized Clinical Trial of 4-Hydroxyphenylretinamide for High-Grade Squamous Intraepithelial Lesions of the Cervix

Michele Follen, E. Neely Atkinson, David Schottenfeld, Anais Malpica, Loyd West, Scott Lippman, Changping Zou, Walter N. Hittelman, Reuben Lotan, Waun Ki Hong
Journal: Clinical Cancer Research
Clin Cancer Res (2001) 7 (11): 3356–3365.
Published: 01 November 2001
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Cyclin D1 and p16 Alterations in Advanced Premalignant Lesions of the Upper Aerodigestive Tract: Role in Response to Chemoprevention and Cancer Development

Vassiliki A. Papadimitrakopoulou, Julie Izzo, Li Mao, Jamie Keck, David Hamilton, Dong Moon Shin, Adel El-Naggar, Petra den Hollander, Diane Liu, Walter N. Hittelman, Waun K. Hong
Journal: Clinical Cancer Research
Clin Cancer Res (2001) 7 (10): 3127–3134.
Published: 01 October 2001
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Expression of Vascular Endothelial Growth Factor and Microvessel Density in Head and Neck Tumorigenesis

Kyung Tae, Adel K. El-Naggar, Enise Yoo, Lei Feng, J. Jack Lee, Waun Ki Hong, Walter N. Hittelman, Dong M. Shin
Journal: Clinical Cancer Research
Clin Cancer Res (2000) 6 (7): 2821–2828.
Published: 01 July 2000
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Predicting Cancer Development in Oral Leukoplakia: Ten Years of Translational Research

J. Jack Lee, Waun Ki Hong, Walter N. Hittelman, Li Mao, Reuben Lotan, Dong M. Shin, Steven E. Benner, Xiao-Chun Xu, Jin S. Lee, Vali M. Papadimitrakopoulou, Clarissa Geyer, Cherie Perez, Jack W. Martin, Adel K. El-Naggar, Scott. M. Lippman
Journal: Clinical Cancer Research
Clin Cancer Res (2000) 6 (5): 1702–1710.
Published: 01 May 2000
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