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W. Gillies McKenna
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Journal Articles

Mitochondrial Inhibitor Atovaquone Increases Tumor Oxygenation and Inhibits Hypoxic Gene Expression in Patients with Non–Small Cell Lung Cancer

Michael Skwarski, Daniel R. McGowan, Elizabeth Belcher, Francesco Di Chiara, Dionisios Stavroulias, Mark McCole, Jennifer L. Derham, Kwun-Ye Chu, Eugene Teoh, Jagat Chauhan, Dawn O’Reilly, Benjamin H.L. Harris, Philip S. Macklin, Joshua A. Bull, Marcus Green, Gonzalo Rodriguez-Berriguete, Remko Prevo, Lisa K. Folkes, Leticia Campo, Petra Ferencz, Paula L. Croal, Helen Flight, Cathy Qi, Jane Holmes, James P.B. O’Connor, Fergus V. Gleeson, W. Gillies McKenna, Adrian L. Harris, Daniel Bulte, Francesca M. Buffa, Ruth E. Macpherson, Geoff S. Higgins
Journal: Clinical Cancer Research
Clin Cancer Res (2021) 27 (9): 2459–2469.
https://doi.org/10.1158/1078-0432.CCR-20-4128
Published: 01 May 2021
View article titled, Mitochondrial Inhibitor Atovaquone Increases Tumor Oxygenation and Inhibits Hypoxic Gene Expression in Patients with Non–Small Cell Lung Cancer
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Includes: Supplementary data
Journal Articles

Oxidative Phosphorylation as an Emerging Target in Cancer Therapy

Thomas M. Ashton, W. Gillies McKenna, Leoni A. Kunz-Schughart, Geoff S. Higgins
Journal: Clinical Cancer Research
Clin Cancer Res (2018) 24 (11): 2482–2490.
https://doi.org/10.1158/1078-0432.CCR-17-3070
Published: 31 May 2018
View article titled, Oxidative Phosphorylation as an Emerging Target in Cancer Therapy
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Journal Articles

Modulation of the Tumor Microvasculature by Phosphoinositide-3 Kinase Inhibition Increases Doxorubicin Delivery In Vivo

Naseer Qayum, Jaehong Im, Michael R. Stratford, Eric J. Bernhard, W. Gillies McKenna, Ruth J. Muschel
Journal: Clinical Cancer Research
Clin Cancer Res (2012) 18 (1): 161–169.
https://doi.org/10.1158/1078-0432.CCR-11-1413
Published: 02 January 2012
View article titled, Modulation of the Tumor Microvasculature by Phosphoinositide-3 Kinase Inhibition Increases Doxorubicin Delivery <em>In Vivo</em>
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Includes: Supplementary data
Journal Articles

A Phase I Trial of the Dual Farnesyltransferase and Geranylgeranyltransferase Inhibitor L-778,123 and Radiotherapy for Locally Advanced Pancreatic Cancer

Neil E. Martin, Thomas B. Brunner, Krystina D. Kiel, Thomas F. DeLaney, William F. Regine, Mohammed Mohiuddin, Ernest F. Rosato, Daniel G. Haller, James P. Stevenson, Debbie Smith, Barnali Pramanik, Joel Tepper, Wesley K. Tanaka, Briggs Morrison, Paul Deutsch, Anjali K. Gupta, Ruth J. Muschel, W. Gillies McKenna, Eric J. Bernhard, Stephen M. Hahn
Journal: Clinical Cancer Research
Clin Cancer Res (2004) 10 (16): 5447–5454.
https://doi.org/10.1158/1078-0432.CCR-04-0248
Published: 24 August 2004
View article titled, A Phase I Trial of the Dual Farnesyltransferase and Geranylgeranyltransferase Inhibitor L-778,123 and Radiotherapy for Locally Advanced Pancreatic Cancer
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Journal Articles

A Phase I Trial of the Farnesyltransferase Inhibitor L-778,123 and Radiotherapy for Locally Advanced Lung and Head and Neck Cancer

Stephen M. Hahn, Eric J. Bernhard, William Regine, Mohammed Mohiuddin, Daniel G. Haller, James P. Stevenson, Debbie Smith, Barnali Pramanik, Joel Tepper, Thomas F. DeLaney, Krystina D. Kiel, Briggs Morrison, Paul Deutsch, Ruth J. Muschel, W. Gillies McKenna
Journal: Clinical Cancer Research
Clin Cancer Res (2002) 8 (5): 1065–1072.
Published: 01 May 2002
View article titled, A Phase I Trial of the Farnesyltransferase Inhibitor L-778,123 and Radiotherapy for Locally Advanced Lung and Head and Neck Cancer
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Journal Articles

Local Recurrence in Head and Neck Cancer: Relationship to Radiation Resistance and Signal Transduction

Anjali K. Gupta, W. Gillies McKenna, Charles N. Weber, Michael D. Feldman, Jeffrey D. Goldsmith, Rosemarie Mick, Mitchell Machtay, David I. Rosenthal, Vincent J. Bakanauskas, George J. Cerniglia, Eric J. Bernhard, Randal S. Weber, Ruth J. Muschel
Journal: Clinical Cancer Research
Clin Cancer Res (2002) 8 (3): 885–892.
Published: 01 March 2002
View article titled, Local Recurrence in Head and Neck Cancer: <subtitle>Relationship to Radiation Resistance and Signal Transduction</subtitle>
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Journal Articles

The Clinical Implications of Gemcitabine Radiosensitization

Todd H. Doyle, Francoise Mornex, W. Gillies McKenna
Journal: Clinical Cancer Research
Clin Cancer Res (2001) 7 (2): 226–228.
Published: 01 February 2001
View article titled, The Clinical Implications of Gemcitabine Radiosensitization
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