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Journal Articles

Biomarkers of Efficacy and Safety of the Academic BCMA-CART ARI0002h for the Treatment of Refractory Multiple Myeloma

Aina Oliver-Caldes, Marta Español-Rego, Aintzane Zabaleta, Verónica González-Calle, Sergio Navarro-Velázquez, Susana Inogés, Ascensión López-Díaz de Cerio, Valentín Cabañas, Nieves López-Muñoz, Paula Rodríguez-Otero, Juan Luis Reguera, David F. Moreno, Nuria Martínez-Cibrian, Lucía López-Corral, Lorena Pérez-Amill, Beatriz Martin-Antonio, Laura Rosiñol, Joan Cid, Natalia Tovar, Joaquín Sáez-Peñataro, Miriam López-Parra, Eulalia Olesti, Elena Guillén, Sara Varea, Luis Gerardo Rodríguez-Lobato, Anthony M. Battram, Marta Sonia González, Andrés Sánchez-Salinas, Azucena González-Navarro, Valentín Ortiz-Maldonado, Julio Delgado, Felipe Prósper, Manel Juan, Joaquín Martínez-López, José M. Moraleda, Maria Victoria Mateos, Álvaro Urbano-Ispizua, Bruno Paiva, Mariona Pascal, Carlos Fernández de Larrea
Journal: Clinical Cancer Research
Clin Cancer Res (2024) 30 (10): 2085–2096.
https://doi.org/10.1158/1078-0432.CCR-23-3759
Published: 15 May 2024
View article titled, Biomarkers of Efficacy and Safety of the Academic BCMA-CART ARI0002h for the Treatment of Refractory Multiple Myeloma
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Includes: Supplementary data
Journal Articles

Short-Chain Fatty Acid Production by Gut Microbiota Predicts Treatment Response in Multiple Myeloma

Alba Rodríguez-García, Andrés Arroyo, Roberto García-Vicente, María Luz Morales, Rubén Gómez-Gordo, Pablo Justo, Clara Cuéllar, José Sánchez-Pina, Nieves López, Rafael Alonso, Noemí Puig, María-Victoria Mateos, Rosa Ayala, Dulcenombre Gómez-Garre, Joaquín Martínez-López, María Linares
Journal: Clinical Cancer Research
Clin Cancer Res (2024) 30 (4): 904–917.
https://doi.org/10.1158/1078-0432.CCR-23-0195
Published: 16 February 2024
View article titled, Short-Chain Fatty Acid Production by Gut Microbiota Predicts Treatment Response in Multiple Myeloma
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Includes: Supplementary data
Journal Articles

A Phase I/II Open-Label Study of Molibresib for the Treatment of Relapsed/Refractory Hematologic Malignancies

Mark A. Dawson, Gautam Borthakur, Brian J.P. Huntly, Anastasios Karadimitris, Adrian Alegre, Aristeidis Chaidos, Dan T. Vogl, Daniel A. Pollyea, Faith E. Davies, Gareth J. Morgan, Jacob L. Glass, Manali Kamdar, Maria-Victoria Mateos, Natalia Tovar, Paul Yeh, Regina García Delgado, Faisal Basheer, Ludovica Marando, Paolo Gallipoli, Anastasia Wyce, Anu Shilpa Krishnatry, Olena Barbash, Evi Bakirtzi, Geraldine Ferron-Brady, Natalie O. Karpinich, Michael T. McCabe, Shawn W. Foley, Thierry Horner, Arindam Dhar, Brandon E. Kremer, Michael Dickinson
Journal: Clinical Cancer Research
Clin Cancer Res (2023) 29 (4): 711–722.
https://doi.org/10.1158/1078-0432.CCR-22-1284
Published: 16 February 2023
View article titled, A Phase I/II Open-Label Study of Molibresib for the Treatment of Relapsed/Refractory Hematologic Malignancies
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Includes: Supplementary data
Journal Articles

Circulating Tumor and Immune Cells for Minimally Invasive Risk Stratification of Smoldering Multiple Myeloma

Rosalinda Termini, David Žihala, Evangelos Terpos, Albert Perez-Montaña, Tomáš Jelínek, Marc Raab, Niels Weinhold, Elias K. Mai, Anna Luise Grab, Jill Corre, Francois Vergez, Antonio Sacco, Marco Chiarini, Viviana Giustini, Alessandra Tucci, Sara Rodriguez, Cristina Moreno, Cristina Perez, Catarina Maia, Esperanza Martín-Sánchez, Camilla Guerrero, Cirino Botta, Juan-Jose Garces, Aitziber Lopez, Luis-Esteban Tamariz-Amador, Felipe Prosper, Joan Bargay, Maria-Elena Cabezudo, Enrique M. Ocio, Roman Hájek, Joaquin Martinez-Lopez, Fernando Solano, Rebeca Iglesias, Artur Paiva, Catarina Geraldes, Helena Vitoria, Clara Gomez, Felipe De Arriba, Heinz Ludwig, Antoni Garcia-Guiñon, Maria Casanova, Adrian Alegre, Valentin Cabañas, Maialen Sirvent, Albert Oriol, Javier de la Rubia, José-Ángel Hernández-Rivas, Luis Palomera, Maria Sarasa, Pablo Rios, Noemi Puig, Maria-Victoria Mateos, Juan Flores-Montero, Alberto Orfao, Hartmut Goldschmidt, Hervé Avet-Loiseau, Aldo M. Roccaro, Jesus F. San-Miguel, Bruno Paiva, on behalf of the PETHEMA/GEM and iMMunocell Cooperative Groups
Journal: Clinical Cancer Research
Clin Cancer Res (2022) 28 (21): 4771–4781.
https://doi.org/10.1158/1078-0432.CCR-22-1594
Published: 01 November 2022
View article titled, Circulating Tumor and Immune Cells for Minimally Invasive Risk Stratification of Smoldering Multiple Myeloma
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Includes: Supplementary data
Journal Articles

A Machine Learning Model Based on Tumor and Immune Biomarkers to Predict Undetectable MRD and Survival Outcomes in Multiple Myeloma

Camila Guerrero, Noemi Puig, Maria-Teresa Cedena, Ibai Goicoechea, Cristina Perez, Juan-José Garcés, Cirino Botta, Maria-Jose Calasanz, Norma C. Gutierrez, Maria-Luisa Martin-Ramos, Albert Oriol, Rafael Rios, Miguel-Teodoro Hernandez, Rafael Martinez-Martinez, Joan Bargay, Felipe de Arriba, Luis Palomera, Ana Pilar Gonzalez-Rodriguez, Adrian Mosquera-Orgueira, Marta-Sonia Gonzalez-Perez, Joaquin Martinez-Lopez, Juan-José Lahuerta, Laura Rosiñol, Joan Blade, Maria-Victoria Mateos, Jesus F. San-Miguel, Bruno Paiva
Journal: Clinical Cancer Research
Clin Cancer Res (2022) 28 (12): 2598–2609.
https://doi.org/10.1158/1078-0432.CCR-21-3430
Published: 13 June 2022
View article titled, A Machine Learning Model Based on Tumor and Immune Biomarkers to Predict Undetectable MRD and Survival Outcomes in Multiple Myeloma
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Includes: Supplementary data
Journal Articles

Minimal Residual Disease in Myeloma: Application for Clinical Care and New Drug Registration

Kenneth C. Anderson, Daniel Auclair, Stacey J. Adam, Amit Agarwal, Melissa Anderson, Hervé Avet-Loiseau, Mark Bustoros, Jessica Chapman, Dana E. Connors, Ajeeta Dash, Alessandra Di Bacco, Ling Du, Thierry Facon, Juan Flores-Montero, Francesca Gay, Irene M. Ghobrial, Nicole J. Gormley, Ira Gupta, Howard Higley, Jens Hillengass, Bindu Kanapuru, Dickran Kazandjian, Gary J. Kelloff, Ilan R. Kirsch, Brandon Kremer, Ola Landgren, Elizabeth Lightbody, Oliver C. Lomas, Sagar Lonial, María-Victoria Mateos, Rocio Montes de Oca, Lata Mukundan, Nikhil C. Munshi, Elizabeth K. O'Donnell, Alberto Orfao, Bruno Paiva, Reshma Patel, Trevor J. Pugh, Karthik Ramasamy, Jill Ray, Mikhail Roshal, Jeremy A. Ross, Caroline C. Sigman, Katie L. Thoren, Suzanne Trudel, Gary Ulaner, Nancy Valente, Brendan M. Weiss, Elena Zamagni, Shaji K. Kumar
Journal: Clinical Cancer Research
Clin Cancer Res (2021) 27 (19): 5195–5212.
https://doi.org/10.1158/1078-0432.CCR-21-1059
Published: 01 October 2021
View article titled, Minimal Residual Disease in Myeloma: Application for Clinical Care and New Drug Registration
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Journal Articles

First-in-Human Phase I Study of ABBV-838, an Antibody–Drug Conjugate Targeting SLAMF7/CS1 in Patients with Relapsed and Refractory Multiple Myeloma

Ravi Vij, Rajneesh Nath, Daniel E.H. Afar, María-Victoria Mateos, Jesús G. Berdeja, Marc S. Raab, Andreas Guenther, Joaquín Martínez-López, Andrzej J. Jakubowiak, Xavier Leleu, Katja Weisel, Shekman Wong, Scott Gulbranson, James P. Sheridan, Anita Reddy, Bruno Paiva, Anil Singhal, Jesús F. San-Miguel, Philippe Moreau
Journal: Clinical Cancer Research
Clin Cancer Res (2020) 26 (10): 2308–2317.
https://doi.org/10.1158/1078-0432.CCR-19-1431
Published: 15 May 2020
View article titled, First-in-Human Phase I Study of ABBV-838, an Antibody–Drug Conjugate Targeting SLAMF7/CS1 in Patients with Relapsed and Refractory Multiple Myeloma
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Includes: Supplementary data
Journal Articles

Amiloride, An Old Diuretic Drug, Is a Potential Therapeutic Agent for Multiple Myeloma

Elizabeta A. Rojas, Luis Antonio Corchete, Laura San-Segundo, Juan F. Martínez-Blanch, Francisco M. Codoñer, Teresa Paíno, Noemí Puig, Ramón García-Sanz, María Victoria Mateos, Enrique M. Ocio, Irena Misiewicz-Krzeminska, Norma C. Gutiérrez
Journal: Clinical Cancer Research
Clin Cancer Res (2017) 23 (21): 6602–6615.
https://doi.org/10.1158/1078-0432.CCR-17-0678
Published: 31 October 2017
View article titled, Amiloride, An Old Diuretic Drug, Is a Potential Therapeutic Agent for Multiple Myeloma
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Includes: Supplementary data
Journal Articles

Multiple Myeloma Patients Have a Specific Serum Metabolomic Profile That Changes after Achieving Complete Remission

Leonor Puchades-Carrasco, Ramón Lecumberri, Joaquín Martínez-López, Juan-José Lahuerta, María-Victoria Mateos, Felipe Prósper, Jesús F. San-Miguel, Antonio Pineda-Lucena
Journal: Clinical Cancer Research
Series: Author Choice
Clin Cancer Res (2013) 19 (17): 4770–4779.
https://doi.org/10.1158/1078-0432.CCR-12-2917
Published: 02 September 2013
View article titled, Multiple Myeloma Patients Have a Specific Serum Metabolomic Profile That Changes after Achieving Complete Remission
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Includes: Supplementary data
Journal Articles

The Progression from MGUS to Smoldering Myeloma and Eventually to Multiple Myeloma Involves a Clonal Expansion of Genetically Abnormal Plasma Cells

Lucía López-Corral, Norma C. Gutiérrez, Maria Belén Vidriales, Maria Victoria Mateos, Ana Rasillo, Ramón García-Sanz, Bruno Paiva, Jesús F. San Miguel
Journal: Clinical Cancer Research
Clin Cancer Res (2011) 17 (7): 1692–1700.
https://doi.org/10.1158/1078-0432.CCR-10-1066
Published: 31 March 2011
View article titled, The Progression from MGUS to Smoldering Myeloma and Eventually to Multiple Myeloma Involves a Clonal Expansion of Genetically Abnormal Plasma Cells
Open the PDF for The Progression from MGUS to Smoldering Myeloma and Eventually to Multiple Myeloma Involves a Clonal Expansion of Genetically Abnormal Plasma Cells in another window
Includes: Supplementary data
Journal Articles

Phase II Clinical and Pharmacokinetic Study of Plitidepsin 3-Hour Infusion Every Two Weeks Alone or with Dexamethasone in Relapsed and Refractory Multiple Myeloma

María Victoria Mateos, Maria Teresa Cibeira, Paul G. Richardson, Felipe Prosper, Albert Oriol, Javier de la Rubia, Juan José Lahuerta, Ramón García-Sanz, Sonia Extremera, Sergio Szyldergemajn, Claudia Corrado, Harald Singer, Constantine S. Mitsiades, Kenneth C. Anderson, Joan Bladé, Jesús San Miguel
Journal: Clinical Cancer Research
Clin Cancer Res (2010) 16 (12): 3260–3269.
https://doi.org/10.1158/1078-0432.CCR-10-0469
Published: 14 June 2010
View article titled, Phase II Clinical and Pharmacokinetic Study of Plitidepsin 3-Hour Infusion Every Two Weeks Alone or with Dexamethasone in Relapsed and Refractory Multiple Myeloma
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Journal Articles

Allogeneic Transplant with Reduced Intensity Conditioning Regimens may Overcome the Poor Prognosis of B-Cell Chronic Lymphocytic Leukemia with Unmutated Immunoglobulin Variable Heavy-Chain Gene and Chromosomal Abnormalities (11q− and 17p−)

Dolores Caballero, Jose A. García-Marco, Rodrigo Martino, Victoria Mateos, José M. Ribera, José Sarrá, Angel León, Guillermo Sanz, Javier de la Serna, Rafael Cabrera, Marcos González, Jorge Sierra, Jesús San Miguel
Journal: Clinical Cancer Research
Clin Cancer Res (2005) 11 (21): 7757–7763.
https://doi.org/10.1158/1078-0432.CCR-05-0941
Published: 08 November 2005
View article titled, Allogeneic Transplant with Reduced Intensity Conditioning Regimens may Overcome the Poor Prognosis of B-Cell Chronic Lymphocytic Leukemia with Unmutated Immunoglobulin Variable Heavy-Chain Gene and Chromosomal Abnormalities (11q− and 17p−)
Open the PDF for Allogeneic Transplant with Reduced Intensity Conditioning Regimens may Overcome the Poor Prognosis of B-Cell Chronic Lymphocytic Leukemia with Unmutated Immunoglobulin Variable Heavy-Chain Gene and Chromosomal Abnormalities (11q− and 17p−) in another window
Journal Articles

Genetic Abnormalities and Patterns of Antigenic Expression in Multiple Myeloma

Gema Mateo, Mariana Castellanos, Ana Rasillo, Norma C. Gutiérrez, Ma. Angeles Montalbán, Ma. Luisa Martín, Jesús Ma. Hernández, Ma. Consuelo López-Berges, Laura Montejano, Joan Bladé, Ma. Victoria Mateos, Anna Sureda, Javier de la Rubia, Joaquín Díaz-Mediavilla, Atanasio Pandiella, Juan José Lahuerta, Alberto Orfao, Jesús F. San Miguel
Journal: Clinical Cancer Research
Clin Cancer Res (2005) 11 (10): 3661–3667.
https://doi.org/10.1158/1078-0432.CCR-04-1489
Published: 16 May 2005
View article titled, Genetic Abnormalities and Patterns of Antigenic Expression in Multiple Myeloma
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