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Vicente Valero
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Journal Articles

Maintenance Pembrolizumab Therapy in Patients with Metastatic HER2-negative Breast Cancer with Prior Response to Chemotherapy

Toshiaki Iwase, Evan N. Cohen, Hui Gao, Angela Alexander, Megumi Kai, Vivian Chiv, Xiaoping Wang, Savitri Krishnamurthy, Diane Liu, Yu Shen, Kumiko Kida, Alexandre Reuben, Rachel M. Layman, David L. Ramirez, Debasish Tripathy, Stacy L. Moulder, Clinton Yam, Vicente Valero, Bora Lim, James M. Reuben, Naoto T. Ueno
Journal: Clinical Cancer Research
Clin Cancer Res (2024) 30 (11): 2424–2432.
https://doi.org/10.1158/1078-0432.CCR-23-2947
Published: 03 June 2024
View article titled, Maintenance Pembrolizumab Therapy in Patients with Metastatic HER2-negative Breast Cancer with Prior Response to Chemotherapy
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Includes: Supplementary data
Journal Articles

Molecular Characterization and Prospective Evaluation of Pathologic Response and Outcomes with Neoadjuvant Therapy in Metaplastic Triple-Negative Breast Cancer

Clinton Yam, Nour Abuhadra, Ryan Sun, Beatriz E. Adrada, Qing-Qing Ding, Jason B. White, Elizabeth E. Ravenberg, Alyson R. Clayborn, Vicente Valero, Debu Tripathy, Senthilkumar Damodaran, Banu K. Arun, Jennifer K. Litton, Naoto T. Ueno, Rashmi K. Murthy, Bora Lim, Luis Baez, Xiaoxian Li, Aman U. Buzdar, Gabriel N. Hortobagyi, Alistair M. Thompson, Elizabeth A. Mittendorf, Gaiane M. Rauch, Rosalind P. Candelaria, Lei Huo, Stacy L. Moulder, Jeffrey T. Chang
Journal: Clinical Cancer Research
Clin Cancer Res (2022) 28 (13): 2878–2889.
https://doi.org/10.1158/1078-0432.CCR-21-3100
Published: 01 July 2022
View article titled, Molecular Characterization and Prospective Evaluation of Pathologic Response and Outcomes with Neoadjuvant Therapy in Metaplastic Triple-Negative Breast Cancer
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Includes: Supplementary data
Journal Articles

Genetic Polymorphisms and Correlation with Treatment-Induced Cardiotoxicity and Prognosis in Patients with Breast Cancer

Parvin F. Peddi, Peter A. Fasching, Duan Liu, Emmanuel Quinaux, Nicholas J. Robert, Vicente Valero, John Crown, Carla Falkson, Adam Brufsky, Julie M. Cunningham, Richard M. Weinshilboum, Tadeusz Pienkowski, Wolfgang Eiermann, Miguel Martín, Valerie Bee, Xiaoyan Wang, Liewei Wang, Eric Yang, Dennis J. Slamon, Sara A. Hurvitz
Journal: Clinical Cancer Research
Clin Cancer Res (2022) 28 (9): 1854–1862.
https://doi.org/10.1158/1078-0432.CCR-21-1762
Published: 02 May 2022
View article titled, Genetic Polymorphisms and Correlation with Treatment-Induced Cardiotoxicity and Prognosis in Patients with Breast Cancer
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Includes: Supplementary data
Journal Articles

Gene Signature–Guided Dasatinib Therapy in Metastatic Breast Cancer

Lajos Pusztai, Stacy Moulder, Mehmet Altan, Danielle Kwiatkowski, Vicente Valero, Naoto T. Ueno, Francisco J. Esteva, Rony Avritscher, Yuan Qi, Lewis Strauss, Gabriel N. Hortobagyi, Christos Hatzis, W. Fraser Symmans
Journal: Clinical Cancer Research
Clin Cancer Res (2014) 20 (20): 5265–5271.
https://doi.org/10.1158/1078-0432.CCR-14-0800
Published: 14 October 2014
View article titled, Gene Signature–Guided Dasatinib Therapy in Metastatic Breast Cancer
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Includes: Supplementary data
Journal Articles

Comparison of circulating tumor cells (CTCs) in metastatic breast cancer (MBC): AdnaTest breast cancer for detection and biological characterization

Eleni Andreopoulou, Diana Urbauer, Savitri Krishnamurthy, James Reuben, Vicente Valero, Massimo Cristofanilli, Herbert Fritsche
Journal: Clinical Cancer Research
Clin Cancer Res (2008) 14 (19_Supplement): A6.
Published: 15 August 2014
View article titled, Comparison of circulating tumor cells (CTCs) in metastatic breast cancer (MBC): <em>AdnaTest breast cancer </em>for detection and biological characterization
Journal Articles

Differential Response to Neoadjuvant Chemotherapy Among 7 Triple-Negative Breast Cancer Molecular Subtypes

Hiroko Masuda, Keith A. Baggerly, Ying Wang, Ya Zhang, Ana Maria Gonzalez-Angulo, Funda Meric-Bernstam, Vicente Valero, Brian D. Lehmann, Jennifer A. Pietenpol, Gabriel N. Hortobagyi, W. Fraser Symmans, Naoto T. Ueno
Journal: Clinical Cancer Research
Series: Author Choice
Clin Cancer Res (2013) 19 (19): 5533–5540.
https://doi.org/10.1158/1078-0432.CCR-13-0799
Published: 01 October 2013
View article titled, Differential Response to Neoadjuvant Chemotherapy Among 7 Triple-Negative Breast Cancer Molecular Subtypes
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Includes: Supplementary data
Journal Articles

Analysis of Fcγ Receptor IIIa and IIa Polymorphisms: Lack of Correlation with Outcome in Trastuzumab-Treated Breast Cancer Patients

Sara A. Hurvitz, David J. Betting, Howard M. Stern, Emmanuel Quinaux, Jeremy Stinson, Somasekar Seshagiri, Ying Zhao, Marc Buyse, John Mackey, Adrian Driga, Sambasivarao Damaraju, Mark X. Sliwkowski, Nicholas J. Robert, Vicente Valero, John Crown, Carla Falkson, Adam Brufsky, Tadeusz Pienkowski, Wolfgang Eiermann, Miguel Martin, Valerie Bee, Omkar Marathe, Dennis J. Slamon, John M. Timmerman
Journal: Clinical Cancer Research
Clin Cancer Res (2012) 18 (12): 3478–3486.
https://doi.org/10.1158/1078-0432.CCR-11-2294
Published: 14 June 2012
View article titled, Analysis of Fcγ Receptor IIIa and IIa Polymorphisms: Lack of Correlation with Outcome in Trastuzumab-Treated Breast Cancer Patients
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Includes: Supplementary data
Journal Articles

Evaluation of a 30-Gene Paclitaxel, Fluorouracil, Doxorubicin, and Cyclophosphamide Chemotherapy Response Predictor in a Multicenter Randomized Trial in Breast Cancer

Adel Tabchy, Vicente Valero, Tatiana Vidaurre, Ana Lluch, Henry Gomez, Miguel Martin, Yuan Qi, Luis Javier Barajas-Figueroa, Eduardo Souchon, Charles Coutant, Franco D. Doimi, Nuhad K. Ibrahim, Yun Gong, Gabriel N. Hortobagyi, Kenneth R. Hess, W. Fraser Symmans, Lajos Pusztai
Journal: Clinical Cancer Research
Clin Cancer Res (2010) 16 (21): 5351–5361.
https://doi.org/10.1158/1078-0432.CCR-10-1265
Published: 31 October 2010
View article titled, Evaluation of a 30-Gene Paclitaxel, Fluorouracil, Doxorubicin, and Cyclophosphamide Chemotherapy Response Predictor in a Multicenter Randomized Trial in Breast Cancer
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Includes: Supplementary data
Journal Articles

Phase II, Randomized Trial to Compare Anastrozole Combined with Gefitinib or Placebo in Postmenopausal Women with Hormone Receptor–Positive Metastatic Breast Cancer

Massimo Cristofanilli, Vicente Valero, Aroop Mangalik, Melanie Royce, Ian Rabinowitz, Francis P. Arena, Joan F. Kroener, Elizabeth Curcio, Claire Watkins, Sarah Bacus, Elsa M. Cora, Elizabeth Anderson, Patrick J. Magill
Journal: Clinical Cancer Research
Clin Cancer Res (2010) 16 (6): 1904–1914.
https://doi.org/10.1158/1078-0432.CCR-09-2282
Published: 14 March 2010
View article titled, Phase II, Randomized Trial to Compare Anastrozole Combined with Gefitinib or Placebo in Postmenopausal Women with Hormone Receptor–Positive Metastatic Breast Cancer
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Includes: Supplementary data
Journal Articles

Integrative Analysis of Cyclin Protein Levels Identifies Cyclin B1 as a Classifier and Predictor of Outcomes in Breast Cancer

Roshan Agarwal, Ana-Maria Gonzalez-Angulo, Simen Myhre, Mark Carey, Ju-Seog Lee, Jens Overgaard, Jan Alsner, Katherine Stemke-Hale, Ana Lluch, Richard M. Neve, Wen Lin Kuo, Therese Sorlie, Aysegul Sahin, Vicente Valero, Khandan Keyomarsi, Joe W. Gray, Anne-Lise Borresen-Dale, Gordon B. Mills, Bryan T. Hennessy
Journal: Clinical Cancer Research
Clin Cancer Res (2009) 15 (11): 3654–3662.
https://doi.org/10.1158/1078-0432.CCR-08-3293
Published: 01 June 2009
View article titled, Integrative Analysis of Cyclin Protein Levels Identifies Cyclin B1 as a Classifier and Predictor of Outcomes in Breast Cancer
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Includes: Supplementary data
Journal Articles

Phase I/II Study of G3139 (Bcl-2 Antisense Oligonucleotide) in Combination with Doxorubicin and Docetaxel in Breast Cancer

Stacy L. Moulder, W. Fraser Symmans, Daniel J. Booser, Timothy L. Madden, Cindy Lipsanen, Linda Yuan, Abenaa M. Brewster, Massimo Cristofanilli, Kelly K. Hunt, Thomas A. Buchholz, James Zwiebel, Vicente Valero, Gabriel N. Hortobagyi, Francisco J. Esteva
Journal: Clinical Cancer Research
Clin Cancer Res (2008) 14 (23): 7909–7916.
https://doi.org/10.1158/1078-0432.CCR-08-1104
Published: 01 December 2008
View article titled, Phase I/II Study of G3139 (Bcl-2 Antisense Oligonucleotide) in Combination with Doxorubicin and Docetaxel in Breast Cancer
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Journal Articles

Comparison of Ductal Lavage and Random Periareolar Fine Needle Aspiration as Tissue Acquisition Methods in Early Breast Cancer Prevention Trials

Banu Arun, Vicente Valero, Catherine Logan, Kristine Broglio, Edgardo Rivera, Abenaa Brewster, Guosheng Yin, Marjorie Green, Henry Kuerer, Yun Gong, Doris Browne, Gabriel N. Hortobagyi, Nour Sneige
Journal: Clinical Cancer Research
Clin Cancer Res (2007) 13 (16): 4943–4948.
https://doi.org/10.1158/1078-0432.CCR-06-2732
Published: 15 August 2007
View article titled, Comparison of Ductal Lavage and Random Periareolar Fine Needle Aspiration as Tissue Acquisition Methods in Early Breast Cancer Prevention Trials
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Journal Articles

Neoadjuvant Therapy with Paclitaxel followed by 5-Fluorouracil, Epirubicin, and Cyclophosphamide Chemotherapy and Concurrent Trastuzumab in Human Epidermal Growth Factor Receptor 2–Positive Operable Breast Cancer: An Update of the Initial Randomized Study Population and Data of Additional Patients Treated with the Same Regimen

Aman U. Buzdar, Vicente Valero, Nuhad K. Ibrahim, Deborah Francis, Kristine R. Broglio, Richard L. Theriault, Lajos Pusztai, Marjorie C. Green, Sonja E. Singletary, Kelly K. Hunt, Aysegul A. Sahin, Francisco Esteva, William F. Symmans, Michael S. Ewer, Thomas A. Buchholz, Gabriel N. Hortobagyi
Journal: Clinical Cancer Research
Clin Cancer Res (2007) 13 (1): 228–233.
https://doi.org/10.1158/1078-0432.CCR-06-1345
Published: 02 January 2007
View article titled, Neoadjuvant Therapy with Paclitaxel followed by 5-Fluorouracil, Epirubicin, and Cyclophosphamide Chemotherapy and Concurrent Trastuzumab in Human Epidermal Growth Factor Receptor 2–Positive Operable Breast Cancer: An Update of the Initial Randomized Study Population and Data of Additional Patients Treated with the Same Regimen
Open the PDF for Neoadjuvant Therapy with Paclitaxel followed by 5-Fluorouracil, Epirubicin, and Cyclophosphamide Chemotherapy and Concurrent Trastuzumab in Human Epidermal Growth Factor Receptor 2–Positive Operable Breast Cancer: An Update of the Initial Randomized Study Population and Data of Additional Patients Treated with the Same Regimen in another window
Journal Articles

p53 Expression as a Prognostic Marker in Inflammatory Breast Cancer

Ana M. Gonzalez-Angulo, Nour Sneige, Aman U. Buzdar, Vicente Valero, Shu-Wan Kau, Kristine Broglio, Yuko Yamamura, Gabriel N. Hortobagyi, Massimo Cristofanilli
Journal: Clinical Cancer Research
Clin Cancer Res (2004) 10 (18): 6215–6221.
https://doi.org/10.1158/1078-0432.CCR-04-0202
Published: 24 September 2004
View article titled, p53 Expression as a Prognostic Marker in Inflammatory Breast Cancer
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Journal Articles

A Phase I and Pharmacokinetic Study of TAS-108 in Postmenopausal Female Patients with Locally Advanced, Locally Recurrent Inoperable, or Progressive Metastatic Breast Cancer

L. Johnetta Blakely, Aman Buzdar, Hsiu-Yin Chang, Debra Frye, Richard Theriault, Vicente Valero, Edgardo Rivera, Daniel Booser, Jun Kuritani, Masuhiro Tsuda
Journal: Clinical Cancer Research
Clin Cancer Res (2004) 10 (16): 5425–5431.
https://doi.org/10.1158/1078-0432.CCR-04-0321
Published: 24 August 2004
View article titled, A Phase I and Pharmacokinetic Study of TAS-108 in Postmenopausal Female Patients with Locally Advanced, Locally Recurrent Inoperable, or Progressive Metastatic Breast Cancer
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Journal Articles

Pilot Study Evaluating the Pharmacokinetics, Pharmacodynamics, and Safety of the Combination of Exemestane and Tamoxifen

Edgardo Rivera, Vicente Valero, Deborah Francis, Aviva G. Asnis, Larry J. Schaaf, Barbara Duncan, Gabriel N. Hortobagyi
Journal: Clinical Cancer Research
Clin Cancer Res (2004) 10 (6): 1943–1948.
https://doi.org/10.1158/1078-0432.CCR-1005-03
Published: 24 March 2004
View article titled, Pilot Study Evaluating the Pharmacokinetics, Pharmacodynamics, and Safety of the Combination of Exemestane and Tamoxifen
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Journal Articles

Gene Expression Profiles Obtained from Fine-Needle Aspirations of Breast Cancer Reliably Identify Routine Prognostic Markers and Reveal Large-Scale Molecular Differences between Estrogen-negative and Estrogen-positive Tumors

Lajos Pusztai, Mark Ayers, James Stec, Edward Clark, Kenneth Hess, David Stivers, Andrew Damokosh, Nour Sneige, Thomas A. Buchholz, Francisco J. Esteva, Banu Arun, Massimo Cristofanilli, Daniel Booser, Marguerite Rosales, Vicente Valero, Constantine Adams, Gabriel N. Hortobagyi, W. Fraser Symmans
Journal: Clinical Cancer Research
Clin Cancer Res (2003) 9 (7): 2406–2415.
Published: 01 July 2003
View article titled, Gene Expression Profiles Obtained from Fine-Needle Aspirations of Breast Cancer Reliably Identify Routine Prognostic Markers and Reveal Large-Scale Molecular Differences between Estrogen-negative and Estrogen-positive Tumors
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Journal Articles

A Phase I Study of Docetaxel Plus Cyclophosphamide in Solid Tumors followed by a Phase II Study as First-Line Therapy in Metastatic Breast Cancer

Jonathan C. Trent, Vicente Valero, Daniel J. Booser, Laura T. Esparza-Guerra, Nuhad Ibrahim, Zia Rahman, Laurent Vernillet, Shreyaskumar Patel, Cynthia L. David, James L. Murray, Massimo Cristofanilli, Gabriel N. Hortobagyi
Journal: Clinical Cancer Research
Clin Cancer Res (2003) 9 (7): 2426–2434.
Published: 01 July 2003
View article titled, A Phase I Study of Docetaxel Plus Cyclophosphamide in Solid Tumors followed by a Phase II Study as First-Line Therapy in Metastatic Breast Cancer
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Journal Articles

A Detailed Evaluation of Cardiac Toxicity: A Phase II Study of Doxorubicin and One- or Three-Hour-Infusion Paclitaxel in Patients with Metastatic Breast Cancer

Sharon H. Giordano, Daniel J. Booser, James L. Murray, Nuhad K. Ibrahim, Zia U. Rahman, Vicente Valero, Richard L. Theriault, Marguerite F. Rosales, Edgardo Rivera, Debbie Frye, Michael Ewer, Nelson G. Ordonez, Aman U. Buzdar, Gabriel N. Hortobagyi
Journal: Clinical Cancer Research
Clin Cancer Res (2002) 8 (11): 3360–3368.
Published: 01 November 2002
View article titled, A Detailed Evaluation of Cardiac Toxicity: <subtitle>A Phase II Study of Doxorubicin and One- or Three-Hour-Infusion Paclitaxel in Patients with Metastatic Breast Cancer</subtitle>
Open the PDF for A Detailed Evaluation of Cardiac Toxicity: <subtitle>A Phase II Study of Doxorubicin and One- or Three-Hour-Infusion Paclitaxel in Patients with Metastatic Breast Cancer</subtitle> in another window
Journal Articles

Evaluation of Paclitaxel in Adjuvant Chemotherapy for Patients with Operable Breast Cancer: Preliminary Data of a Prospective Randomized Trial

Aman U. Buzdar, S. Eva Singletary, Vicente Valero, Daniel J. Booser, Nuhad K. Ibrahim, Zia Rahman, Richard L. Theriault, Ronald Walters, Edgardo Rivera, Terry L. Smith, Frankie A. Holmes, Emma Hoy, Debra K. Frye, Nikki Manuel, Shu-Wan Kau, Marsha D. McNeese, Eric Strom, Eva Thomas, Kelly Hunt, Fred Ames, Donald Berry, Gabriel N. Hortobagyi
Journal: Clinical Cancer Research
Clin Cancer Res (2002) 8 (5): 1073–1079.
Published: 01 May 2002
View article titled, Evaluation of Paclitaxel in Adjuvant Chemotherapy for Patients with Operable Breast Cancer: <subtitle>Preliminary Data of a Prospective Randomized Trial</subtitle>
Open the PDF for Evaluation of Paclitaxel in Adjuvant Chemotherapy for Patients with Operable Breast Cancer: <subtitle>Preliminary Data of a Prospective Randomized Trial</subtitle> in another window