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Vamsidhar Velcheti
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Journal Articles

Objective Analysis and Clinical Significance of the Spatial Tumor-Infiltrating Lymphocyte Patterns in Non–Small Cell Lung Cancer

Miguel Lopez de Rodas, Yvonne Wang, Gang Peng, Jianlei Gu, Mari Mino-Kenudson, Jonathan W. Riess, Vamsidhar Velcheti, Matthew Hellmann, Justin F. Gainor, Hongyu Zhao, Kurt A. Schalper
Journal: Clinical Cancer Research
Clin Cancer Res (2024) 30 (5): 998–1008.
https://doi.org/10.1158/1078-0432.CCR-23-2457
Published: 01 March 2024
View article titled, Objective Analysis and Clinical Significance of the Spatial Tumor-Infiltrating Lymphocyte Patterns in Non–Small Cell Lung Cancer
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Journal Articles

Novel Radiomic Measurements of Tumor-Associated Vasculature Morphology on Clinical Imaging as a Biomarker of Treatment Response in Multiple Cancers

Nathaniel Braman, Prateek Prasanna, Kaustav Bera, Mehdi Alilou, Mohammadhadi Khorrami, Patrick Leo, Maryam Etesami, Manasa Vulchi, Paulette Turk, Amit Gupta, Prantesh Jain, Pingfu Fu, Nathan Pennell, Vamsidhar Velcheti, Jame Abraham, Donna Plecha, Anant Madabhushi
Journal: Clinical Cancer Research
Clin Cancer Res (2022) 28 (20): 4410–4424.
https://doi.org/10.1158/1078-0432.CCR-21-4148
Published: 14 October 2022
View article titled, Novel Radiomic Measurements of Tumor-Associated Vasculature Morphology on Clinical Imaging as a Biomarker of Treatment Response in Multiple Cancers
Open the PDF for Novel Radiomic Measurements of Tumor-Associated Vasculature Morphology on Clinical Imaging as a Biomarker of Treatment Response in Multiple Cancers in another window
Includes: Supplementary data
Journal Articles

Activity of Adagrasib (MRTX849) in Brain Metastases: Preclinical Models and Clinical Data from Patients with KRASG12C-Mutant Non–Small Cell Lung Cancer

Joshua K. Sabari, Vamsidhar Velcheti, Kazuhide Shimizu, Matthew R. Strickland, Rebecca S. Heist, Mohini Singh, Naema Nayyar, Anita Giobbie-Hurder, Subba R. Digumarthy, Justin F. Gainor, Anant P. Rajan, Edwin Nieblas-Bedolla, Aaron C. Burns, Jill Hallin, Peter Olson, James G. Christensen, Sylvia C. Kurz, Priscilla K. Brastianos, Hiroaki Wakimoto
Journal: Clinical Cancer Research
Clin Cancer Res (2022) 28 (15): 3318–3328.
https://doi.org/10.1158/1078-0432.CCR-22-0383
Published: 02 August 2022
View article titled, Activity of Adagrasib (MRTX849) in Brain Metastases: Preclinical Models and Clinical Data from Patients with KRAS<sup>G12C</sup>-Mutant Non–Small Cell Lung Cancer
Open the PDF for Activity of Adagrasib (MRTX849) in Brain Metastases: Preclinical Models and Clinical Data from Patients with KRAS<sup>G12C</sup>-Mutant Non–Small Cell Lung Cancer in another window
Includes: Supplementary data
Journal Articles

PD-L1 Crosslinking as a New Strategy of 4-1BB Agonism Immunotherapy

Fei Shu, Salman R. Punekar, Vamsidhar Velcheti, Miguel F. Sanmamed, Jun Wang
Journal: Clinical Cancer Research
Clin Cancer Res (2022) 28 (15): 3182–3184.
https://doi.org/10.1158/1078-0432.CCR-22-0541
Published: 02 August 2022
View article titled, PD-L1 Crosslinking as a New Strategy of 4-1BB Agonism Immunotherapy
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Journal Articles

Expression Analysis and Significance of PD-1, LAG-3, and TIM-3 in Human Non–Small Cell Lung Cancer Using Spatially Resolved and Multiparametric Single-Cell Analysis

Ila Datar, Miguel F. Sanmamed, Jun Wang, Brian S. Henick, Jungmin Choi, Ti Badri, Weilai Dong, Nikita Mani, Maria Toki, Luis D. Mejías, Maria D. Lozano, Jose Luis Perez-Gracia, Vamsidhar Velcheti, Matthew D. Hellmann, Justin F. Gainor, Kristen McEachern, David Jenkins, Konstantinos Syrigos, Katerina Politi, Scott Gettinger, David L. Rimm, Roy S. Herbst, Ignacio Melero, Lieping Chen, Kurt A. Schalper
Journal: Clinical Cancer Research
Clin Cancer Res (2019) 25 (15): 4663–4673.
https://doi.org/10.1158/1078-0432.CCR-18-4142
Published: 01 August 2019
View article titled, Expression Analysis and Significance of PD-1, LAG-3, and TIM-3 in Human Non–Small Cell Lung Cancer Using Spatially Resolved and Multiparametric Single-Cell Analysis
Open the PDF for Expression Analysis and Significance of PD-1, LAG-3, and TIM-3 in Human Non–Small Cell Lung Cancer Using Spatially Resolved and Multiparametric Single-Cell Analysis in another window
Includes: Supplementary data
Journal Articles

Spatial Architecture and Arrangement of Tumor-Infiltrating Lymphocytes for Predicting Likelihood of Recurrence in Early-Stage Non–Small Cell Lung Cancer

Germán Corredor, Xiangxue Wang, Yu Zhou, Cheng Lu, Pingfu Fu, Konstantinos Syrigos, David L. Rimm, Michael Yang, Eduardo Romero, Kurt A. Schalper, Vamsidhar Velcheti, Anant Madabhushi
Journal: Clinical Cancer Research
Clin Cancer Res (2019) 25 (5): 1526–1534.
https://doi.org/10.1158/1078-0432.CCR-18-2013
Published: 01 March 2019
View article titled, Spatial Architecture and Arrangement of Tumor-Infiltrating Lymphocytes for Predicting Likelihood of Recurrence in Early-Stage Non–Small Cell Lung Cancer
Open the PDF for Spatial Architecture and Arrangement of Tumor-Infiltrating Lymphocytes for Predicting Likelihood of Recurrence in Early-Stage Non–Small Cell Lung Cancer in another window
Includes: Supplementary data
Journal Articles

Phase I Trial of ALT-803, A Novel Recombinant IL15 Complex, in Patients with Advanced Solid Tumors

Kim Margolin, Chihiro Morishima, Vamsidhar Velcheti, Jeffrey S. Miller, Sylvia M. Lee, Ann W. Silk, Shernan G. Holtan, Andreanne M. Lacroix, Steven P. Fling, Judith C. Kaiser, Jack O. Egan, Monica Jones, Peter R. Rhode, Amy D. Rock, Martin A. Cheever, Hing C. Wong, Marc S. Ernstoff
Journal: Clinical Cancer Research
Clin Cancer Res (2018) 24 (22): 5552–5561.
https://doi.org/10.1158/1078-0432.CCR-18-0945
Published: 15 November 2018
View article titled, Phase I Trial of ALT-803, A Novel Recombinant IL15 Complex, in Patients with Advanced Solid Tumors
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Includes: Supplementary data
Journal Articles

Spatially Resolved and Quantitative Analysis of VISTA/PD-1H as a Novel Immunotherapy Target in Human Non–Small Cell Lung Cancer

Franz Villarroel-Espindola, Xiaoqing Yu, Ila Datar, Nikita Mani, Miguel Sanmamed, Vamsidhar Velcheti, Konstantinos Syrigos, Maria Toki, Hongyu Zhao, Lieping Chen, Roy S. Herbst, Kurt A. Schalper
Journal: Clinical Cancer Research
Clin Cancer Res (2018) 24 (7): 1562–1573.
https://doi.org/10.1158/1078-0432.CCR-17-2542
Published: 02 April 2018
View article titled, Spatially Resolved and Quantitative Analysis of VISTA/PD-1H as a Novel Immunotherapy Target in Human Non–Small Cell Lung Cancer
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Includes: Supplementary data
Journal Articles

Differential Expression and Significance of PD-L1, IDO-1, and B7-H4 in Human Lung Cancer

Kurt A. Schalper, Daniel Carvajal-Hausdorf, Joseph McLaughlin, Mehmet Altan, Vamsidhar Velcheti, Patricia Gaule, Miguel F. Sanmamed, Lieping Chen, Roy S. Herbst, David L. Rimm
Journal: Clinical Cancer Research
Clin Cancer Res (2017) 23 (2): 370–378.
https://doi.org/10.1158/1078-0432.CCR-16-0150
Published: 15 January 2017
View article titled, Differential Expression and Significance of PD-L1, IDO-1, and B7-H4 in Human Lung Cancer
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Includes: Supplementary data
Journal Articles

Evaluation of PD-L1 Expression and Associated Tumor-Infiltrating Lymphocytes in Laryngeal Squamous Cell Carcinoma

Maria Vassilakopoulou, Margaritis Avgeris, Vamsidhar Velcheti, Vassiliki Kotoula, Theodore Rampias, Kyriakos Chatzopoulos, Christos Perisanidis, Christos K. Kontos, Aris I. Giotakis, Andreas Scorilas, David Rimm, Clarence Sasaki, George Fountzilas, Amanda Psyrri
Journal: Clinical Cancer Research
Clin Cancer Res (2016) 22 (3): 704–713.
https://doi.org/10.1158/1078-0432.CCR-15-1543
Published: 31 January 2016
View article titled, Evaluation of PD-L1 Expression and Associated Tumor-Infiltrating Lymphocytes in Laryngeal Squamous Cell Carcinoma
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Includes: Supplementary data
Journal Articles

In Situ Tumor PD-L1 mRNA Expression Is Associated with Increased TILs and Better Outcome in Breast Carcinomas

Kurt A. Schalper, Vamsidhar Velcheti, Daniel Carvajal, Hallie Wimberly, Jason Brown, Lajos Pusztai, David L. Rimm
Journal: Clinical Cancer Research
Clin Cancer Res (2014) 20 (10): 2773–2782.
https://doi.org/10.1158/1078-0432.CCR-13-2702
Published: 14 May 2014
View article titled, <em>In Situ</em> Tumor PD-L1 mRNA Expression Is Associated with Increased TILs and Better Outcome in Breast Carcinomas
Open the PDF for <em>In Situ</em> Tumor PD-L1 mRNA Expression Is Associated with Increased TILs and Better Outcome in Breast Carcinomas in another window
Includes: Supplementary data