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Valerie W. Rusch
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Journal Articles

Systemic and Oligo-Acquired Resistance to PD-(L)1 Blockade in Lung Cancer

Adam J. Schoenfeld, Hira A. Rizvi, Danish Memon, Narek Shaverdian, Matthew J. Bott, Jennifer L. Sauter, C. Jillian Tsai, Jayon Lihm, David Hoyos, Andrew J. Plodkowski, Rocio Perez-Johnston, Peter Sawan, Jacklynn V. Egger, Benjamin D. Greenbaum, Andreas Rimner, Gregory J. Riely, Charles M. Rudin, Valerie W. Rusch, Daniel R. Gomez, Matthew D. Hellmann
Journal: Clinical Cancer Research
Clin Cancer Res (2022) 28 (17): 3797–3803.
https://doi.org/10.1158/1078-0432.CCR-22-0657
Published: 01 September 2022
View article titled, Systemic and Oligo-Acquired Resistance to PD-(L)1 Blockade in Lung Cancer
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Includes: Supplementary data
Journal Articles

Comprehensive Molecular and Clinicopathologic Analysis of 200 Pulmonary Invasive Mucinous Adenocarcinomas Identifies Distinct Characteristics of Molecular Subtypes

Jason C. Chang, Michael Offin, Christina Falcon, David Brown, Brian R. Houck-Loomis, Fanli Meng, Vasilisa A. Rudneva, Helen H. Won, Sharon Amir, Joseph Montecalvo, Patrice Desmeules, Kyuichi Kadota, Prasad S. Adusumilli, Valerie W. Rusch, Sarah Teed, Joshua K. Sabari, Ryma Benayed, Khedoudja Nafa, Laetitia Borsu, Bob T. Li, Alison M. Schram, Maria E. Arcila, William D. Travis, Marc Ladanyi, Alexander Drilon, Natasha Rekhtman
Journal: Clinical Cancer Research
Clin Cancer Res (2021) 27 (14): 4066–4076.
https://doi.org/10.1158/1078-0432.CCR-21-0423
Published: 15 July 2021
View article titled, Comprehensive Molecular and Clinicopathologic Analysis of 200 Pulmonary Invasive Mucinous Adenocarcinomas Identifies Distinct Characteristics of Molecular Subtypes
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Includes: Supplementary data
Journal Articles

KRASG12C Mutation Is Associated with Increased Risk of Recurrence in Surgically Resected Lung Adenocarcinoma

Gregory D. Jones, Raul Caso, Kay See Tan, Brooke Mastrogiacomo, Francisco Sanchez-Vega, Yuan Liu, James G. Connolly, Yonina R. Murciano-Goroff, Matthew J. Bott, Prasad S. Adusumilli, Daniela Molena, Gaetano Rocco, Valerie W. Rusch, Smita Sihag, Sandra Misale, Rona Yaeger, Alexander Drilon, Kathryn C. Arbour, Gregory J. Riely, Neal Rosen, Piro Lito, Haiying Zhang, David C. Lyden, Charles M. Rudin, David R. Jones, Bob T. Li, James M. Isbell
Journal: Clinical Cancer Research
Clin Cancer Res (2021) 27 (9): 2604–2612.
https://doi.org/10.1158/1078-0432.CCR-20-4772
Published: 01 May 2021
View article titled, <em>KRAS</em><sup>G12C</sup> Mutation Is Associated with Increased Risk of Recurrence in Surgically Resected Lung Adenocarcinoma
Open the PDF for <em>KRAS</em><sup>G12C</sup> Mutation Is Associated with Increased Risk of Recurrence in Surgically Resected Lung Adenocarcinoma in another window
Includes: Supplementary data
Journal Articles

Analysis of Tumor Genomic Pathway Alterations Using Broad-Panel Next-Generation Sequencing in Surgically Resected Lung Adenocarcinoma

Jian Zhou, Francisco Sanchez-Vega, Raul Caso, Kay See Tan, Whitney S. Brandt, Gregory D. Jones, Shi Yan, Prasad S. Adusumilli, Matthew Bott, James Huang, James M. Isbell, Smita Sihag, Daniela Molena, Valerie W. Rusch, Walid K. Chatila, Natasha Rekhtman, Fan Yang, Marc Ladanyi, David B. Solit, Michael F. Berger, Nikolaus Schultz, David R. Jones
Journal: Clinical Cancer Research
Clin Cancer Res (2019) 25 (24): 7475–7484.
https://doi.org/10.1158/1078-0432.CCR-19-1651
Published: 13 December 2019
View article titled, Analysis of Tumor Genomic Pathway Alterations Using Broad-Panel Next-Generation Sequencing in Surgically Resected Lung Adenocarcinoma
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Includes: Supplementary data
Journal Articles

Comprehensive Next-Generation Sequencing Unambiguously Distinguishes Separate Primary Lung Carcinomas From Intrapulmonary Metastases: Comparison with Standard Histopathologic Approach

Jason C. Chang, Deepu Alex, Matthew Bott, Kay See Tan, Venkatraman Seshan, Andrew Golden, Jennifer L. Sauter, Darren J. Buonocore, Chad M. Vanderbilt, Sounak Gupta, Patrice Desmeules, Francis M. Bodd, Gregory J. Riely, Valerie W. Rusch, David R. Jones, Maria E. Arcila, William D. Travis, Marc Ladanyi, Natasha Rekhtman
Journal: Clinical Cancer Research
Clin Cancer Res (2019) 25 (23): 7113–7125.
https://doi.org/10.1158/1078-0432.CCR-19-1700
Published: 02 December 2019
View article titled, Comprehensive Next-Generation Sequencing Unambiguously Distinguishes Separate Primary Lung Carcinomas From Intrapulmonary Metastases: Comparison with Standard Histopathologic Approach
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Includes: Supplementary data
Journal Articles

A Randomized Phase II Trial of Adjuvant Galinpepimut-S, WT-1 Analogue Peptide Vaccine, After Multimodality Therapy for Patients with Malignant Pleural Mesothelioma

Marjorie G. Zauderer, Anne S. Tsao, Tao Dao, Katherine Panageas, W. Victoria Lai, Andreas Rimner, Valerie W. Rusch, Prasad S. Adusumilli, Michelle S. Ginsberg, Daniel Gomez, David Rice, Reza Mehran, David A. Scheinberg, Lee M. Krug
Journal: Clinical Cancer Research
Clin Cancer Res (2017) 23 (24): 7483–7489.
https://doi.org/10.1158/1078-0432.CCR-17-2169
Published: 14 December 2017
View article titled, A Randomized Phase II Trial of Adjuvant Galinpepimut-S, WT-1 Analogue Peptide Vaccine, After Multimodality Therapy for Patients with Malignant Pleural Mesothelioma
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Includes: Supplementary data
Journal Articles

Mesothelin Overexpression Is a Marker of Tumor Aggressiveness and Is Associated with Reduced Recurrence-Free and Overall Survival in Early-Stage Lung Adenocarcinoma

Stefan S. Kachala, Adam J. Bograd, Jonathan Villena-Vargas, Kei Suzuki, Elliot L. Servais, Kyuichi Kadota, Joanne Chou, Camelia S. Sima, Eva Vertes, Valerie W. Rusch, William D. Travis, Michel Sadelain, Prasad S. Adusumilli
Journal: Clinical Cancer Research
Clin Cancer Res (2014) 20 (4): 1020–1028.
https://doi.org/10.1158/1078-0432.CCR-13-1862
Published: 16 February 2014
View article titled, Mesothelin Overexpression Is a Marker of Tumor Aggressiveness and Is Associated with Reduced Recurrence-Free and Overall Survival in Early-Stage Lung Adenocarcinoma
Open the PDF for Mesothelin Overexpression Is a Marker of Tumor Aggressiveness and Is Associated with Reduced Recurrence-Free and Overall Survival in Early-Stage Lung Adenocarcinoma in another window
Includes: Supplementary data
Journal Articles

Mesothelin Overexpression Promotes Mesothelioma Cell Invasion and MMP-9 Secretion in an Orthotopic Mouse Model and in Epithelioid Pleural Mesothelioma Patients

Elliot L. Servais, Christos Colovos, Luis Rodriguez, Adam J. Bograd, Jun-ichi Nitadori, Camelia Sima, Valerie W. Rusch, Michel Sadelain, Prasad S. Adusumilli
Journal: Clinical Cancer Research
Clin Cancer Res (2012) 18 (9): 2478–2489.
https://doi.org/10.1158/1078-0432.CCR-11-2614
Published: 30 April 2012
View article titled, Mesothelin Overexpression Promotes Mesothelioma Cell Invasion and MMP-9 Secretion in an Orthotopic Mouse Model and in Epithelioid Pleural Mesothelioma Patients
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Includes: Supplementary data
Journal Articles

Prognostic Immune Markers in Non–Small Cell Lung Cancer

Kei Suzuki, Stefan S. Kachala, Kyuichi Kadota, Ronglai Shen, Qianxing Mo, David G. Beer, Valerie W. Rusch, William D. Travis, Prasad S. Adusumilli
Journal: Clinical Cancer Research
Clin Cancer Res (2011) 17 (16): 5247–5256.
https://doi.org/10.1158/1078-0432.CCR-10-2805
Published: 14 August 2011
View article titled, Prognostic Immune Markers in Non–Small Cell Lung Cancer
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Includes: Supplementary data
Journal Articles

Comprehensive Genomic Analysis Reveals Clinically Relevant Molecular Distinctions between Thymic Carcinomas and Thymomas

Nicolas Girard, Ronglai Shen, Tianhua Guo, Maureen F. Zakowski, Adriana Heguy, Gregory J. Riely, James Huang, Christopher Lau, Alex E. Lash, Marc Ladanyi, Agnes Viale, Cristina R. Antonescu, William D. Travis, Valerie W. Rusch, Mark G. Kris, William Pao
Journal: Clinical Cancer Research
Clin Cancer Res (2009) 15 (22): 6790–6799.
https://doi.org/10.1158/1078-0432.CCR-09-0644
Published: 11 November 2009
View article titled, Comprehensive Genomic Analysis Reveals Clinically Relevant Molecular Distinctions between Thymic Carcinomas and Thymomas
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Includes: Supplementary data
Journal Articles

Homozygous Deletion of CDKN2A and Codeletion of the Methylthioadenosine Phosphorylase Gene in the Majority of Pleural Mesotheliomas

Peter B. Illei, Valerie W. Rusch, Maureen F. Zakowski, Marc Ladanyi
Journal: Clinical Cancer Research
Clin Cancer Res (2003) 9 (6): 2108–2113.
Published: 01 June 2003
View article titled, Homozygous Deletion of <em>CDKN2A</em> and Codeletion of the Methylthioadenosine Phosphorylase Gene in the Majority of Pleural Mesotheliomas
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Journal Articles

Experimental Therapeutics with a New 10-Deazaaminopterin in Human Mesothelioma: Further Improving Efficacy through Structural Design, Pharmacologic Modulation at the Level of MRP ATPases, and Combined Therapy with Platinums

Nushmia Z. Khokhar, Yuhong She, Valerie W. Rusch, F. M. Sirotnak
Journal: Clinical Cancer Research
Clin Cancer Res (2001) 7 (10): 3199–3205.
Published: 01 October 2001
View article titled, Experimental Therapeutics with a New 10-Deazaaminopterin in Human Mesothelioma: <subtitle>Further Improving Efficacy through Structural Design, Pharmacologic Modulation at the Level of MRP ATPases, and Combined Therapy with Platinums</subtitle>
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