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Uwe Zangemeister-Wittke
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Journal Articles

Correction: Targeting the Phosphoinositide 3-Kinase p110-α Isoform Impairs Cell Proliferation, Survival, and Tumor Growth in Small Cell Lung Cancer

Anna Wojtalla, Barbara Fischer, Nataliya Kotelevets, Francesco A. Mauri, Jens Sobek, Hubert Rehrauer, Carlos Wotzkow, Mario P. Tschan, Michael J. Seckl, Uwe Zangemeister-Wittke, Alexandre Arcaro
Journal: Clinical Cancer Research
Clin Cancer Res (2025) 31 (4): 787.
https://doi.org/10.1158/1078-0432.CCR-25-0031
Published: 17 February 2025
View articletitled, Correction: Targeting the Phosphoinositide 3-Kinase p110-α Isoform Impairs Cell Proliferation, Survival, and Tumor Growth in Small Cell Lung Cancer
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Journal Articles

Targeting the Phosphoinositide 3-Kinase p110-α Isoform Impairs Cell Proliferation, Survival, and Tumor Growth in Small Cell Lung Cancer

Anna Wojtalla, Barbara Fischer, Nataliya Kotelevets, Francesco A. Mauri, Jens Sobek, Hubert Rehrauer, Carlos Wotzkow, Mario P. Tschan, Michael J. Seckl, Uwe Zangemeister-Wittke, Alexandre Arcaro
Journal: Clinical Cancer Research
Clin Cancer Res (2013) 19 (1): 96–105.
https://doi.org/10.1158/1078-0432.CCR-12-1138
Published: 01 January 2013
View articletitled, Targeting the Phosphoinositide 3-Kinase p110-α Isoform Impairs Cell Proliferation, Survival, and Tumor Growth in Small Cell Lung Cancer
Open the PDF for Targeting the Phosphoinositide 3-Kinase p110-α Isoform Impairs Cell Proliferation, Survival, and Tumor Growth in Small Cell Lung Cancer in another window
Includes: Supplementary data
Journal Articles

A Novel Fusion Toxin Derived from an EpCAM-Specific Designed Ankyrin Repeat Protein Has Potent Antitumor Activity

Patricia Martin-Killias, Nikolas Stefan, Sacha Rothschild, Andreas Plückthun, Uwe Zangemeister-Wittke
Journal: Clinical Cancer Research
Clin Cancer Res (2011) 17 (1): 100–110.
https://doi.org/10.1158/1078-0432.CCR-10-1303
Published: 04 January 2011
View articletitled, A Novel Fusion Toxin Derived from an EpCAM-Specific Designed Ankyrin Repeat Protein Has Potent Antitumor Activity
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Includes: Supplementary data
Journal Articles

AKT/mTOR Pathway Activation and BCL-2 Family Proteins Modulate the Sensitivity of Human Small Cell Lung Cancer Cells to RAD001

Marin Marinov, Algirdas Ziogas, Olivier E. Pardo, Liwen Terence Tan, Tony Dhillon, Francesco A. Mauri, Heidi A. Lane, Nicholas R. Lemoine, Uwe Zangemeister-Wittke, Michael J. Seckl, Alexandre Arcaro
Journal: Clinical Cancer Research
Clin Cancer Res (2009) 15 (4): 1277–1287.
https://doi.org/10.1158/1078-0432.CCR-08-2166
Published: 19 February 2009
View articletitled, AKT/mTOR Pathway Activation and BCL-2 Family Proteins Modulate the Sensitivity of Human Small Cell Lung Cancer Cells to RAD001
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Includes: Supplementary data
Journal Articles

Trastuzumab Down-Regulates Bcl-2 Expression and Potentiates Apoptosis Induction by Bcl-2/Bcl-XL Bispecific Antisense Oligonucleotides in HER-2 Gene–Amplified Breast Cancer Cells

Michele Milella, Daniela Trisciuoglio, Tiziana Bruno, Ludovica Ciuffreda, Marcella Mottolese, Anna Cianciulli, Francesco Cognetti, Uwe Zangemeister-Wittke, Donatella Del Bufalo, Gabriella Zupi
Journal: Clinical Cancer Research
Clin Cancer Res (2004) 10 (22): 7747–7756.
https://doi.org/10.1158/1078-0432.CCR-04-0908
Published: 29 November 2004
View articletitled, Trastuzumab Down-Regulates Bcl-2 Expression and Potentiates Apoptosis Induction by Bcl-2/Bcl-XL Bispecific Antisense Oligonucleotides in HER-2 Gene–Amplified Breast Cancer Cells
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Journal Articles

A Recombinant Immunotoxin Derived from a Humanized Epithelial Cell Adhesion Molecule-specific Single-Chain Antibody Fragment Has Potent and Selective Antitumor Activity

Claudio Di Paolo, Jörg Willuda, Susanne Kubetzko, Ikar Lauffer, Dominique Tschudi, Robert Waibel, Andreas Plückthun, Rolf A. Stahel, Uwe Zangemeister-Wittke
Journal: Clinical Cancer Research
Clin Cancer Res (2003) 9 (7): 2837–2848.
Published: 01 July 2003
View articletitled, A Recombinant Immunotoxin Derived from a Humanized Epithelial Cell Adhesion Molecule-specific Single-Chain Antibody Fragment Has Potent and Selective Antitumor Activity
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Journal Articles

Combined Targeted Inhibition of bcl -2, bcl -XL, Epidermal Growth Factor Receptor, and Protein Kinase A Type I Causes Potent Antitumor, Apoptotic, and Antiangiogenic Activity

Giampaolo Tortora, Rosa Caputo, Vincenzo Damiano, Roberta Caputo, Teresa Troiani, Bianca Maria Veneziani, Sabino De Placido, Angelo Raffaele Bianco, Uwe Zangemeister-Wittke, Fortunato Ciardiello
Journal: Clinical Cancer Research
Clin Cancer Res (2003) 9 (2): 866–871.
Published: 01 February 2003
View articletitled, Combined Targeted Inhibition of bcl -2, bcl -XL, Epidermal Growth Factor Receptor, and Protein Kinase A Type I Causes Potent Antitumor, Apoptotic, and Antiangiogenic Activity
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Journal Articles

p53-independent Induction of Apoptosis in Human Melanoma Cells by a bcl-2/bcl-xL Bispecific Antisense Oligonucleotide

Mary Strasberg Rieber, Uwe Zangemeister-Wittke, Manuel Rieber
Journal: Clinical Cancer Research
Clin Cancer Res (2001) 7 (5): 1446–1451.
Published: 01 May 2001
View articletitled, p53-independent Induction of Apoptosis in Human Melanoma Cells by a bcl-2/bcl-xL Bispecific Antisense Oligonucleotide
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Journal Articles

A Novel Bispecific Antisense Oligonucleotide Inhibiting Both bcl-2 and bcl-xL Expression Efficiently Induces Apoptosis in Tumor Cells

Uwe Zangemeister-Wittke, Siân H. Leech, Robert A. Olie, A. Paula Simões-Wüst, Oliver Gautschi, Gerd H. Luedke, François Natt, Robert Häner, Pierre Martin, Jonathan Hall, Carlo M. Nalin, Rolf A. Stahel
Journal: Clinical Cancer Research
Clin Cancer Res (2000) 6 (6): 2547–2555.
Published: 01 June 2000
View articletitled, A Novel Bispecific Antisense Oligonucleotide Inhibiting Both bcl-2 and bcl-xL Expression Efficiently Induces Apoptosis in Tumor Cells
Open the PDF for A Novel Bispecific Antisense Oligonucleotide Inhibiting Both bcl-2 and bcl-xL Expression Efficiently Induces Apoptosis in Tumor Cells in another window