Page 1 | Search Results | Clinical Cancer Research | American Association for Cancer Research

1-12 of 12

Sort by

Sort Order Select

Journal Articles

STK11/LKB1 Mutations in NSCLC Are Associated with KEAP1/NRF2-Dependent Radiotherapy Resistance Targetable by Glutaminase Inhibition

Piyada Sitthideatphaiboon, Ana Galan-Cobo, Marcelo V. Negrao, Xiao Qu, Alissa Poteete, Fahao Zhang, Diane D. Liu, Whitney E. Lewis, Haley N. Kemp, Jeff Lewis, Waree Rinsurongkawong, Uma Giri, J. Jack Lee, Jianjun Zhang, Jack A. Roth, Stephen Swisher, John V. Heymach

Clin Cancer Res (2021) 27 (6): 1720–1733.

https://doi.org/10.1158/1078-0432.CCR-20-2859

Published: 15 March 2021

View article titled, STK11/LKB1 Mutations in NSCLC Are Associated with KEAP1/NRF2-Dependent Radiotherapy Resistance Targetable by Glutaminase Inhibition

Includes: Supplementary data

Journal Articles

RAD50 Expression Is Associated with Poor Clinical Outcomes after Radiotherapy for Resected Non–small Cell Lung Cancer

Yifan Wang, Jayanthi Gudikote, Uma Giri, Jun Yan, Weiye Deng, Rui Ye, Wen Jiang, Nan Li, Brian P. Hobbs, Jing Wang, Stephen G. Swisher, Junya Fujimoto, Ignacio I. Wistuba, Ritsuko Komaki, John V. Heymach, Steven H. Lin

Clin Cancer Res (2018) 24 (2): 341–350.

https://doi.org/10.1158/1078-0432.CCR-17-1455

Published: 15 January 2018

View article titled, RAD50 Expression Is Associated with Poor Clinical Outcomes after Radiotherapy for Resected Non–small Cell Lung Cancer

Includes: Supplementary data

Journal Articles

The HGF/c-MET Pathway Is a Driver and Biomarker of VEGFR-inhibitor Resistance and Vascular Remodeling in Non–Small Cell Lung Cancer

Clin Cancer Res (2017) 23 (18): 5489–5501.

https://doi.org/10.1158/1078-0432.CCR-16-3216

Published: 14 September 2017

View article titled, The HGF/c-MET Pathway Is a Driver and Biomarker of VEGFR-inhibitor Resistance and Vascular Remodeling in Non–Small Cell Lung Cancer

Includes: Supplementary data

Journal Articles

Integrative Analysis Identifies a Novel AXL–PI3 Kinase–PD-L1 Signaling Axis Associated with Radiation Resistance in Head and Neck Cancer

Heath D. Skinner, Uma Giri, Liang P. Yang, Manish Kumar, Ying Liu, Michael D. Story, Curtis R. Pickering, Lauren A. Byers, Michelle D. Williams, Jing Wang, Li Shen, Suk Y. Yoo, You Hong Fan, David P. Molkentine, Beth M. Beadle, Raymond E. Meyn, Jeffrey N. Myers, John V. Heymach

Clin Cancer Res (2017) 23 (11): 2713–2722.

https://doi.org/10.1158/1078-0432.CCR-16-2586

Published: 31 May 2017

View article titled, Integrative Analysis Identifies a Novel AXL–PI3 Kinase–PD-L1 Signaling Axis Associated with Radiation Resistance in Head and Neck Cancer

Includes: Supplementary data

Journal Articles

Proteomic Profiling Identifies PTK2/FAK as a Driver of Radioresistance in HPV-negative Head and Neck Cancer

Heath D. Skinner, Uma Giri, Liang Yang, Sang Hyeok Woo, Michael D. Story, Curtis R. Pickering, Lauren A. Byers, Michelle D. Williams, Adel El-Naggar, Jing Wang, Lixia Diao, Li Shen, You Hong Fan, David P. Molkentine, Beth M. Beadle, Raymond E. Meyn, Jeffrey N. Myers, John V. Heymach

Clin Cancer Res (2016) 22 (18): 4643–4650.

https://doi.org/10.1158/1078-0432.CCR-15-2785

Published: 15 September 2016

View article titled, Proteomic Profiling Identifies PTK2/FAK as a Driver of Radioresistance in HPV-negative Head and Neck Cancer

Includes: Supplementary data

Journal Articles

KDR Amplification Is Associated with VEGF-Induced Activation of the mTOR and Invasion Pathways but does not Predict Clinical Benefit to the VEGFR TKI Vandetanib

Monique B. Nilsson, Uma Giri, Jayanthi Gudikote, Ximing Tang, Wei Lu, Hai Tran, Youhong Fan, Andrew Koo, Lixia Diao, Pan Tong, Jing Wang, Roy Herbst, Bruce E. Johnson, Andy Ryan, Alan Webster, Philip Rowe, Ignacio I. Wistuba, John V. Heymach

Clin Cancer Res (2016) 22 (8): 1940–1950.

https://doi.org/10.1158/1078-0432.CCR-15-1994

Published: 14 April 2016

View article titled, KDR Amplification Is Associated with VEGF-Induced Activation of the mTOR and Invasion Pathways but does not Predict Clinical Benefit to the VEGFR TKI Vandetanib

Includes: Supplementary data

Journal Articles

Epithelial–Mesenchymal Transition Predicts Polo-Like Kinase 1 Inhibitor–Mediated Apoptosis in Non–Small Cell Lung Cancer

Renata Ferrarotto, Ruchitha Goonatilake, Suk Young Yoo, Pan Tong, Uma Giri, Shaohua Peng, John Minna, Luc Girard, Yuehong Wang, Liguang Wang, Lerong Li, Lixia Diao, David H. Peng, Don L. Gibbons, Bonnie S. Glisson, John V. Heymach, Jing Wang, Lauren A. Byers, Faye M. Johnson

Clin Cancer Res (2016) 22 (7): 1674–1686.

https://doi.org/10.1158/1078-0432.CCR-14-2890

Published: 31 March 2016

View article titled, Epithelial–Mesenchymal Transition Predicts Polo-Like Kinase 1 Inhibitor–Mediated Apoptosis in Non–Small Cell Lung Cancer

Includes: Supplementary data

Journal Articles

Detection of T790M, the Acquired Resistance EGFR Mutation, by Tumor Biopsy versus Noninvasive Blood-Based Analyses

Clin Cancer Res (2016) 22 (5): 1103–1110.

https://doi.org/10.1158/1078-0432.CCR-15-1031

Published: 29 February 2016

View article titled, Detection of T790M, the Acquired Resistance EGFR Mutation, by Tumor Biopsy versus Noninvasive Blood-Based Analyses

Includes: Supplementary data

Journal Articles

An Epithelial–Mesenchymal Transition Gene Signature Predicts Resistance to EGFR and PI3K Inhibitors and Identifies Axl as a Therapeutic Target for Overcoming EGFR Inhibitor Resistance

Clin Cancer Res (2013) 19 (1): 279–290.

https://doi.org/10.1158/1078-0432.CCR-12-1558

Published: 02 January 2013

View article titled, An Epithelial–Mesenchymal Transition Gene Signature Predicts Resistance to EGFR and PI3K Inhibitors and Identifies Axl as a Therapeutic Target for Overcoming EGFR Inhibitor Resistance

Includes: Supplementary data

Journal Articles

Abstract A12: High-throughput mutation analysis of NSCLC circulating tumor cells

Heidi S. Erickson, Nana E. Hanson, Hai Tran, Gordon B. Mills, Ed S. Kim, John V. Heymach, Ignacio I. Wistuba, Hector G. Galindo, Katherine Stemke-Hale, Uma Giri, Christina McDowell, Luc Girard, Jack J. Lee, Roy Herbst, John Minna, Farideh Z. Bischoff

Clin Cancer Res (2012) 18 (3_Supplement): A12.

https://doi.org/10.1158/1078-0432.12AACRIASLC-A12

Published: 01 February 2012

View article titled, Abstract A12: High-throughput mutation analysis of NSCLC circulating tumor cells

Journal Articles

TP53 Disruptive Mutations Lead to Head and Neck Cancer Treatment Failure through Inhibition of Radiation-Induced Senescence

Heath D. Skinner, Vlad C. Sandulache, Thomas J. Ow, Raymond E. Meyn, John S. Yordy, Beth M. Beadle, Alison L. Fitzgerald, Uma Giri, K. Kian Ang, Jeffrey N. Myers

Clin Cancer Res (2012) 18 (1): 290–300.

https://doi.org/10.1158/1078-0432.CCR-11-2260

Published: 02 January 2012

View article titled, TP53 Disruptive Mutations Lead to Head and Neck Cancer Treatment Failure through Inhibition of Radiation-Induced Senescence

Includes: Supplementary data

Journal Articles

DNA Repair Biomarker Profiling of Head and Neck Cancer: Ku80 Expression Predicts Locoregional Failure and Death following Radiotherapy

Benjamin J. Moeller, John S. Yordy, Michelle D. Williams, Uma Giri, Uma Raju, David P. Molkentine, Lauren A. Byers, John V. Heymach, Michael D. Story, J. Jack Lee, Erich M Sturgis, Randal S. Weber, Adam S. Garden, K. Kian Ang, David L. Schwartz

Clin Cancer Res (2011) 17 (7): 2035–2043.

https://doi.org/10.1158/1078-0432.CCR-10-2641

Published: 31 March 2011

View article titled, DNA Repair Biomarker Profiling of Head and Neck Cancer: Ku80 Expression Predicts Locoregional Failure and Death following Radiotherapy

Includes: Supplementary data

NARROW

STK11/LKB1 Mutations in NSCLC Are Associated with KEAP1/NRF2-Dependent Radiotherapy Resistance Targetable by Glutaminase Inhibition

RAD50 Expression Is Associated with Poor Clinical Outcomes after Radiotherapy for Resected Non–small Cell Lung Cancer

The HGF/c-MET Pathway Is a Driver and Biomarker of VEGFR-inhibitor Resistance and Vascular Remodeling in Non–Small Cell Lung Cancer

Integrative Analysis Identifies a Novel AXL–PI3 Kinase–PD-L1 Signaling Axis Associated with Radiation Resistance in Head and Neck Cancer

Proteomic Profiling Identifies PTK2/FAK as a Driver of Radioresistance in HPV-negative Head and Neck Cancer

KDR Amplification Is Associated with VEGF-Induced Activation of the mTOR and Invasion Pathways but does not Predict Clinical Benefit to the VEGFR TKI Vandetanib

Epithelial–Mesenchymal Transition Predicts Polo-Like Kinase 1 Inhibitor–Mediated Apoptosis in Non–Small Cell Lung Cancer

Detection of T790M, the Acquired Resistance EGFR Mutation, by Tumor Biopsy versus Noninvasive Blood-Based Analyses

An Epithelial–Mesenchymal Transition Gene Signature Predicts Resistance to EGFR and PI3K Inhibitors and Identifies Axl as a Therapeutic Target for Overcoming EGFR Inhibitor Resistance

Abstract A12: High-throughput mutation analysis of NSCLC circulating tumor cells

TP53 Disruptive Mutations Lead to Head and Neck Cancer Treatment Failure through Inhibition of Radiation-Induced Senescence

DNA Repair Biomarker Profiling of Head and Neck Cancer: Ku80 Expression Predicts Locoregional Failure and Death following Radiotherapy

Email alerts

AACR Journals

Email alerts

AACR Journals

This Feature Is Available To Subscribers Only