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Trisha M. Wise-Draper
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Journal Articles

A First-in-Human Phase I Study of BXQ-350, a First-in-Class Sphingolipid Metabolism Regulator, in Patients with Advanced/Recurrent Solid Tumors or High-Grade Gliomas

Olivier Rixe, John L. Villano, Robert Wesolowski, Anne M. Noonan, Vinay K. Puduvalli, Trisha M. Wise-Draper, Richard Curry, III, Emrullah Yilmaz, Charlie Cruze, Besim Ogretmen, Gilles Tapolsky, Ray Takigiku
Journal: Clinical Cancer Research
Clin Cancer Res (2024) 30 (22): 5053–5060.
https://doi.org/10.1158/1078-0432.CCR-24-1721
Published: 15 November 2024
View article titled, A First-in-Human Phase I Study of BXQ-350, a First-in-Class Sphingolipid Metabolism Regulator, in Patients with Advanced/Recurrent Solid Tumors or High-Grade Gliomas
Open the PDF for A First-in-Human Phase I Study of BXQ-350, a First-in-Class Sphingolipid Metabolism Regulator, in Patients with Advanced/Recurrent Solid Tumors or High-Grade Gliomas in another window
Includes: Supplementary data
Journal Articles

A Phase 0/I Pharmacokinetic and Pharmacodynamics and Safety and Tolerability Study of Letrozole in Combination with Standard Therapy in Recurrent High-Grade Gliomas

Pankaj B. Desai, Aniruddha S. Karve, Misam Zawit, Priyanka Arora, Nimita Dave, Joy Awosika, Ningjing Li, Bethany Fuhrman, Mario Medvedovic, Larry Sallans, Ady Kendler, Biplab DasGupta, David Plas, Richard Curry, Mario Zuccarello, Rekha Chaudhary, Soma Sengupta, Trisha M. Wise-Draper
Journal: Clinical Cancer Research
Clin Cancer Res (2024) 30 (10): 2068–2077.
https://doi.org/10.1158/1078-0432.CCR-23-3341
Published: 15 May 2024
View article titled, A Phase 0/I Pharmacokinetic and Pharmacodynamics and Safety and Tolerability Study of Letrozole in Combination with Standard Therapy in Recurrent High-Grade Gliomas
Open the PDF for A Phase 0/I Pharmacokinetic and Pharmacodynamics and Safety and Tolerability Study of Letrozole in Combination with Standard Therapy in Recurrent High-Grade Gliomas in another window
Includes: Supplementary data
Journal Articles

Durvalumab plus Cetuximab in Patients with Recurrent or Metastatic Head and Neck Squamous Cell Carcinoma: An Open-label, Nonrandomized, Phase II Clinical Trial

Shuchi Gulati, McKenzie Crist, Muhammed Kashif Riaz, Vinita Takiar, Maria Lehn, Ilaina Monroe, Sarah Palackdharry, Nicky Kurtzweil, Roman Jandarov, Nusrat Harun, Trisha M. Wise-Draper
Journal: Clinical Cancer Research
Clin Cancer Res (2023) 29 (10): 1906–1915.
https://doi.org/10.1158/1078-0432.CCR-22-3886
Published: 15 May 2023
View article titled, Durvalumab plus Cetuximab in Patients with Recurrent or Metastatic Head and Neck Squamous Cell Carcinoma: An Open-label, Nonrandomized, Phase II Clinical Trial
Open the PDF for Durvalumab plus Cetuximab in Patients with Recurrent or Metastatic Head and Neck Squamous Cell Carcinoma: An Open-label, Nonrandomized, Phase II Clinical Trial in another window
Includes: Supplementary data
Journal Articles

Phase II Trial of Adjuvant Nivolumab Following Salvage Resection in Patients with Recurrent Squamous Cell Carcinoma of the Head and Neck

Jennifer L. Leddon, Shuchi Gulati, Sulsal Haque, Casey Allen, Sarah Palackdharry, Maria Mathews, Nicky Kurtzweil, Muhammed Kashif Riaz, Vinita Takiar, Misako Nagasaka, Yash Patil, Chad Zender, Alice Tang, Brian Cervenka, Julie McGrath, W. Michael Korn, Benjamin H. Hinrichs, Roman Jandarov, Nusrat Harun, Ammar Sukari, Trisha M. Wise-Draper
Journal: Clinical Cancer Research
Clin Cancer Res (2022) 28 (16): 3464–3472.
https://doi.org/10.1158/1078-0432.CCR-21-4554
Published: 15 August 2022
View article titled, Phase II Trial of Adjuvant Nivolumab Following Salvage Resection in Patients with Recurrent Squamous Cell Carcinoma of the Head and Neck
Open the PDF for Phase II Trial of Adjuvant Nivolumab Following Salvage Resection in Patients with Recurrent Squamous Cell Carcinoma of the Head and Neck in another window
Includes: Supplementary data
Journal Articles

Phase II Clinical Trial of Neoadjuvant and Adjuvant Pembrolizumab in Resectable Local–Regionally Advanced Head and Neck Squamous Cell Carcinoma

Trisha M. Wise-Draper, Shuchi Gulati, Sarah Palackdharry, Benjamin H. Hinrichs, Francis P. Worden, Matthew O. Old, Neal E. Dunlap, John M. Kaczmar, Yash Patil, Muhammed Kashif Riaz, Alice Tang, Jonathan Mark, Chad Zender, Ann M. Gillenwater, Diana Bell, Nicky Kurtzweil, Maria Mathews, Casey L. Allen, Michelle L. Mierzwa, Keith Casper, Roman Jandarov, Mario Medvedovic, J. Jack Lee, Nusrat Harun, Vinita Takiar, Maura Gillison
Journal: Clinical Cancer Research
Clin Cancer Res (2022) 28 (7): 1345–1352.
https://doi.org/10.1158/1078-0432.CCR-21-3351
Published: 01 April 2022
View article titled, Phase II Clinical Trial of Neoadjuvant and Adjuvant Pembrolizumab in Resectable Local–Regionally Advanced Head and Neck Squamous Cell Carcinoma
Open the PDF for Phase II Clinical Trial of Neoadjuvant and Adjuvant Pembrolizumab in Resectable Local–Regionally Advanced Head and Neck Squamous Cell Carcinoma in another window
Includes: Supplementary data
Journal Articles

Abstract PO-094: Glutaminase inhibition increases ionizing radiation induced oxidative stress and DNA damage in head and neck squamous cell carcinoma models

Christina A. Wicker, Brian G. Hunt, Sarah Palackdharry, William R. Elaban, Trisha M. Wise-Draper, Gordon B. Mills, Susan E. Waltz, Vinita Takiar
Journal: Clinical Cancer Research
Clin Cancer Res (2021) 27 (8_Supplement): PO-094.
https://doi.org/10.1158/1557-3265.RADSCI21-PO-094
Published: 15 April 2021
View article titled, Abstract PO-094: Glutaminase inhibition increases ionizing radiation induced oxidative stress and DNA damage in head and neck squamous cell carcinoma models
Journal Articles

Abstract 26: Exosomal microRNA as salivary biomarkers of head and neck squamous cell carcinoma

Scott M. Langevin, Damaris Kuhnell, Xiang Zhang, Trisha M. Wise-Draper, Keith A. Casper
Journal: Clinical Cancer Research
Clin Cancer Res (2017) 23 (23_Supplement): 26.
https://doi.org/10.1158/1557-3265.AACRAHNS17-26
Published: 30 November 2017
View article titled, Abstract 26: Exosomal microRNA as salivary biomarkers of head and neck squamous cell carcinoma