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Journal Articles

Bavituximab Decreases Immunosuppressive Myeloid-Derived Suppressor Cells in Newly Diagnosed Glioblastoma Patients

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K. Ina Ly, Leland G. Richardson, Mofei Liu, Alona Muzikansky, Jonathan Cardona, Kevin Lou, Andrew L. Beers, Ken Chang, James M. Brown, Xiaoyue Ma, David A. Reardon, Isabel C. Arrillaga-Romany, Deborah A. Forst, Justin T. Jordan, Eudocia Q. Lee, Jorg Dietrich, Lakshmi Nayak, Patrick Y. Wen, Ugonma Chukwueke, Anita Giobbie-Hurder, Bryan D. Choi, Tracy T. Batchelor, Jayashree Kalpathy-Cramer, William T. Curry, Elizabeth R. Gerstner
Journal: Clinical Cancer Research
Clin Cancer Res (2023) 29 (16): 3017–3025.
https://doi.org/10.1158/1078-0432.CCR-23-0203
Published: 15 August 2023
View articletitled, Bavituximab Decreases Immunosuppressive Myeloid-Derived Suppressor Cells in Newly Diagnosed Glioblastoma Patients
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Includes: Supplementary data
Journal Articles

PI3K/AKT/mTOR Pathway Alterations Promote Malignant Progression and Xenograft Formation in Oligodendroglial Tumors

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Kensuke Tateishi, Taishi Nakamura, Tareq A. Juratli, Erik A. Williams, Yuko Matsushita, Shigeta Miyake, Mayuko Nishi, Julie J. Miller, Shilpa S. Tummala, Alexandria L. Fink, Nina Lelic, Mara V.A. Koerner, Yohei Miyake, Jo Sasame, Kenji Fujimoto, Takahiro Tanaka, Ryogo Minamimoto, Shigeo Matsunaga, Shigeo Mukaihara, Takashi Shuto, Hiroki Taguchi, Naoko Udaka, Hidetoshi Murata, Akihide Ryo, Shoji Yamanaka, William T. Curry, Dora Dias-Santagata, Tetsuya Yamamoto, Koichi Ichimura, Tracy T. Batchelor, Andrew S. Chi, A. John Iafrate, Hiroaki Wakimoto, Daniel P. Cahill
Journal: Clinical Cancer Research
Clin Cancer Res (2019) 25 (14): 4375–4387.
https://doi.org/10.1158/1078-0432.CCR-18-4144
Published: 15 July 2019
View articletitled, PI3K/AKT/mTOR Pathway Alterations Promote Malignant Progression and Xenograft Formation in Oligodendroglial Tumors
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Includes: Supplementary data
Journal Articles

Dopamine Receptor D5 is a Modulator of Tumor Response to Dopamine Receptor D2 Antagonism

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Varun V. Prabhu, Neel S. Madhukar, Coryandar Gilvary, C. Leah B. Kline, Sophie Oster, Wafik S. El-Deiry, Olivier Elemento, Faye Doherty, Alexander VanEngelenburg, Jessica Durrant, Rohinton S. Tarapore, Sean Deacon, Neil Charter, Jinkyu Jung, Deric M. Park, Mark R. Gilbert, Jessica Rusert, Robert Wechsler-Reya, Isabel Arrillaga-Romany, Tracy T. Batchelor, Patrick Y. Wen, Wolfgang Oster, Joshua E. Allen
Journal: Clinical Cancer Research
Clin Cancer Res (2019) 25 (7): 2305–2313.
https://doi.org/10.1158/1078-0432.CCR-18-2572
Published: 01 April 2019
View articletitled, Dopamine Receptor D5 is a Modulator of Tumor Response to Dopamine Receptor D2 Antagonism
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Includes: Supplementary data
Journal Articles

Phase I and Biomarker Study of Plerixafor and Bevacizumab in Recurrent High-Grade Glioma

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Eudocia Q. Lee, Dan G. Duda, Alona Muzikansky, Elizabeth R. Gerstner, John G. Kuhn, David A. Reardon, Lakshmi Nayak, Andrew D. Norden, Lisa Doherty, Debra LaFrankie, Jennifer Stefanik, Trupti Vardam, Katrina H. Smith, Christine McCluskey, Sarah Gaffey, Tracy T. Batchelor, Rakesh K. Jain, Patrick Y. Wen
Journal: Clinical Cancer Research
Clin Cancer Res (2018) 24 (19): 4643–4649.
https://doi.org/10.1158/1078-0432.CCR-18-1025
Published: 01 October 2018
View articletitled, Phase I and Biomarker Study of Plerixafor and Bevacizumab in Recurrent High-Grade Glioma
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Journal Articles

Diffusion MRI Phenotypes Predict Overall Survival Benefit from Anti-VEGF Monotherapy in Recurrent Glioblastoma: Converging Evidence from Phase II Trials

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Benjamin M. Ellingson, Elizabeth R. Gerstner, Marion Smits, Raymond Y. Huang, Rivka Colen, Lauren E. Abrey, Dana T. Aftab, Gisela M. Schwab, Colin Hessel, Robert J. Harris, Ararat Chakhoyan, Renske Gahrmann, Whitney B. Pope, Kevin Leu, Catalina Raymond, Davis C. Woodworth, John de Groot, Patrick Y. Wen, Tracy T. Batchelor, Martin J. van den Bent, Timothy F. Cloughesy
Journal: Clinical Cancer Research
Clin Cancer Res (2017) 23 (19): 5745–5756.
https://doi.org/10.1158/1078-0432.CCR-16-2844
Published: 01 October 2017
View articletitled, Diffusion MRI Phenotypes Predict Overall Survival Benefit from Anti-VEGF Monotherapy in Recurrent Glioblastoma: Converging Evidence from Phase II Trials
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Journal Articles

Myc-Driven Glycolysis Is a Therapeutic Target in Glioblastoma

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Kensuke Tateishi, A. John Iafrate, Quan Ho, William T. Curry, Tracy T. Batchelor, Keith T. Flaherty, Maristela L. Onozato, Nina Lelic, Sudhandra Sundaram, Daniel P. Cahill, Andrew S. Chi, Hiroaki Wakimoto
Journal: Clinical Cancer Research
Clin Cancer Res (2016) 22 (17): 4452–4465.
https://doi.org/10.1158/1078-0432.CCR-15-2274
Published: 31 August 2016
View articletitled, Myc-Driven Glycolysis Is a Therapeutic Target in Glioblastoma
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Includes: Supplementary data
Journal Articles

Vaccination with Irradiated Autologous Tumor Cells Mixed with Irradiated GM-K562 Cells Stimulates Antitumor Immunity and T Lymphocyte Activation in Patients with Recurrent Malignant Glioma

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William T. Curry, Jr, Ramana Gorrepati, Matthias Piesche, Tetsuro Sasada, Pankaj Agarwalla, Pamela S. Jones, Elizabeth R. Gerstner, Alexandra J. Golby, Tracy T. Batchelor, Patrick Y. Wen, Martin C. Mihm, Glenn Dranoff
Journal: Clinical Cancer Research
Clin Cancer Res (2016) 22 (12): 2885–2896.
https://doi.org/10.1158/1078-0432.CCR-15-2163
Published: 14 June 2016
View articletitled, Vaccination with Irradiated Autologous Tumor Cells Mixed with Irradiated GM-K562 Cells Stimulates Antitumor Immunity and T Lymphocyte Activation in Patients with Recurrent Malignant Glioma
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Includes: Supplementary data
Journal Articles

Treatment Response Assessment in IDH-Mutant Glioma Patients by Noninvasive 3D Functional Spectroscopic Mapping of 2-Hydroxyglutarate

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Ovidiu C. Andronesi, Franziska Loebel, Wolfgang Bogner, Małgorzata Marjańska, Matthew G. Vander Heiden, A. John Iafrate, Jorg Dietrich, Tracy T. Batchelor, Elizabeth R. Gerstner, William G. Kaelin, Andrew S. Chi, Bruce R. Rosen, Daniel P. Cahill
Journal: Clinical Cancer Research
Clin Cancer Res (2016) 22 (7): 1632–1641.
https://doi.org/10.1158/1078-0432.CCR-15-0656
Published: 31 March 2016
View articletitled, Treatment Response Assessment in IDH-Mutant Glioma Patients by Noninvasive 3D Functional Spectroscopic Mapping of 2-Hydroxyglutarate
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Includes: Supplementary data
Journal Articles

A Multicenter, Phase II, Randomized, Noncomparative Clinical Trial of Radiation and Temozolomide with or without Vandetanib in Newly Diagnosed Glioblastoma Patients

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Eudocia Q. Lee, Thomas J. Kaley, Dan G. Duda, David Schiff, Andrew B. Lassman, Eric T. Wong, Tom Mikkelsen, Benjamin W. Purow, Alona Muzikansky, Marek Ancukiewicz, Jason T. Huse, Shakti Ramkissoon, Jan Drappatz, Andrew D. Norden, Rameen Beroukhim, Stephanie E. Weiss, Brian M. Alexander, Christine S. McCluskey, Mary Gerard, Katrina H. Smith, Rakesh K. Jain, Tracy T. Batchelor, Keith L. Ligon, Patrick Y. Wen
Journal: Clinical Cancer Research
Clin Cancer Res (2015) 21 (16): 3610–3618.
https://doi.org/10.1158/1078-0432.CCR-14-3220
Published: 13 August 2015
View articletitled, A Multicenter, Phase II, Randomized, Noncomparative Clinical Trial of Radiation and Temozolomide with or without Vandetanib in Newly Diagnosed Glioblastoma Patients
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Includes: Supplementary data
Journal Articles

Antiangiogenic Therapy for Glioblastoma: Current Status and Future Prospects

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Tracy T. Batchelor, David A. Reardon, John F. de Groot, Wolfgang Wick, Michael Weller
Journal: Clinical Cancer Research
Clin Cancer Res (2014) 20 (22): 5612–5619.
https://doi.org/10.1158/1078-0432.CCR-14-0834
Published: 13 November 2014
View articletitled, Antiangiogenic Therapy for Glioblastoma: Current Status and Future Prospects
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Journal Articles

Targetable Signaling Pathway Mutations Are Associated with Malignant Phenotype in IDH-Mutant Gliomas

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Hiroaki Wakimoto, Shota Tanaka, William T. Curry, Franziska Loebel, Dan Zhao, Kensuke Tateishi, Juxiang Chen, Lindsay K. Klofas, Nina Lelic, James C. Kim, Dora Dias-Santagata, Leif W. Ellisen, Darrell R. Borger, Sarah-Maria Fendt, Matthew G. Vander Heiden, Tracy T. Batchelor, A. John Iafrate, Daniel P. Cahill, Andrew S. Chi
Journal: Clinical Cancer Research
Clin Cancer Res (2014) 20 (11): 2898–2909.
https://doi.org/10.1158/1078-0432.CCR-13-3052
Published: 29 May 2014
View articletitled, Targetable Signaling Pathway Mutations Are Associated with Malignant Phenotype in IDH-Mutant Gliomas
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Includes: Supplementary data
Journal Articles

Loss of the Mismatch Repair Protein MSH6 in Human Glioblastomas Is Associated with Tumor Progression during Temozolomide Treatment

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Daniel P. Cahill, Kymberly K. Levine, Rebecca A. Betensky, Patrick J. Codd, Candice A. Romany, Linsey B. Reavie, Tracy T. Batchelor, P. Andrew Futreal, Michael R. Stratton, William T. Curry, A. John Iafrate, David N. Louis
Journal: Clinical Cancer Research
Clin Cancer Res (2007) 13 (7): 2038–2045.
https://doi.org/10.1158/1078-0432.CCR-06-2149
Published: 02 April 2007
View articletitled, Loss of the Mismatch Repair Protein MSH6 in Human Glioblastomas Is Associated with Tumor Progression during Temozolomide Treatment
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Includes: Supplementary data
Journal Articles

The Effect of Enzyme-Inducing Antiseizure Drugs on the Pharmacokinetics and Tolerability of Procarbazine Hydrochloride

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Stuart A. Grossman, Kathryn A. Carson, Tracy T. Batchelor, Glenn Lesser, Tom Mikkelsen, Jane B. Alavi, Surasak Phuphanich, Tarek Hammour, Joy D. Fisher, Jeffrey G. Supko
Journal: Clinical Cancer Research
Clin Cancer Res (2006) 12 (17): 5174–5181.
https://doi.org/10.1158/1078-0432.CCR-06-0932
Published: 01 September 2006
View articletitled, The Effect of Enzyme-Inducing Antiseizure Drugs on the Pharmacokinetics and Tolerability of Procarbazine Hydrochloride
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Journal Articles

Magnetic Resonance Imaging Characteristics Predict Epidermal Growth Factor Receptor Amplification Status in Glioblastoma

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Manish Aghi, Paola Gaviani, John W. Henson, Tracy T. Batchelor, David N. Louis, Fred G. Barker, II
Journal: Clinical Cancer Research
Clin Cancer Res (2005) 11 (24): 8600–8605.
https://doi.org/10.1158/1078-0432.CCR-05-0713
Published: 16 December 2005
View articletitled, Magnetic Resonance Imaging Characteristics Predict Epidermal Growth Factor Receptor Amplification Status in Glioblastoma
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Journal Articles

YKL-40 Is a Differential Diagnostic Marker for Histologic Subtypes of High-Grade Gliomas

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Catherine L. Nutt, Rebecca A. Betensky, Melissa A. Brower, Tracy T. Batchelor, David N. Louis, Anat O. Stemmer-Rachamimov
Journal: Clinical Cancer Research
Clin Cancer Res (2005) 11 (6): 2258–2264.
https://doi.org/10.1158/1078-0432.CCR-04-1601
Published: 23 March 2005
View articletitled, YKL-40 Is a Differential Diagnostic Marker for Histologic Subtypes of High-Grade Gliomas
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Journal Articles

Treatment of Relapsed Central Nervous System Lymphoma with High-Dose Methotrexate

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Scott R. Plotkin, Rebecca A. Betensky, Fred H. Hochberg, Stuart A. Grossman, Glenn J. Lesser, L. Burt Nabors, Brian Chon, Tracy T. Batchelor
Journal: Clinical Cancer Research
Clin Cancer Res (2004) 10 (17): 5643–5646.
https://doi.org/10.1158/1078-0432.CCR-04-0159
Published: 08 September 2004
View articletitled, Treatment of Relapsed Central Nervous System Lymphoma with High-Dose Methotrexate
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Journal Articles

Age-Dependent Prognostic Effects of Genetic Alterations in Glioblastoma

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Tracy T. Batchelor, Rebecca A. Betensky, J. Matthew Esposito, Loc-Duyen D. Pham, Molly V. Dorfman, Nicole Piscatelli, Sarah Jhung, David Rhee, David N. Louis
Journal: Clinical Cancer Research
Clin Cancer Res (2004) 10 (1): 228–233.
https://doi.org/10.1158/1078-0432.CCR-0841-3
Published: 20 January 2004
View articletitled, Age-Dependent Prognostic Effects of Genetic Alterations in Glioblastoma
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Journal Articles

BCL-6 Expression Predicts Improved Survival in Patients with Primary Central Nervous System Lymphoma

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Kristina M. Braaten, Rebecca A. Betensky, Laurence de Leval, Yoshifumi Okada, Fred H. Hochberg, David N. Louis, Nancy L. Harris, Tracy T. Batchelor
Journal: Clinical Cancer Research
Clin Cancer Res (2003) 9 (3): 1063–1069.
Published: 01 March 2003
View articletitled, BCL-6 Expression Predicts Improved Survival in Patients with Primary Central Nervous System Lymphoma
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Journal Articles

High-Dose Methotrexate for Intraocular Lymphoma

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Tracy T. Batchelor, Gina Kolak, Roberto Ciordia, C. Stephen Foster, John W. Henson
Journal: Clinical Cancer Research
Clin Cancer Res (2003) 9 (2): 711–715.
Published: 01 February 2003
View articletitled, High-Dose Methotrexate for Intraocular Lymphoma
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