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Todd A. Fehniger
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Journal Articles

First-in-Human Phase I Study of a CD16A Bispecific Innate Cell Engager, AFM24, Targeting EGFR-Expressing Solid Tumors

Anthony El-Khoueiry, Omar Saavedra, Jacob Thomas, Claire Livings, Elena Garralda, Gabriele Hintzen, Laura Kohlhas, Dessislava Vanosmael, Joachim Koch, Erich Rajkovic, Paulien Ravenstijn, Paolo Nuciforo, Todd A. Fehniger, Mark Foster, Melissa M. Berrien-Elliott, Susanne Wingert, Sina Stäble, Daniela Morales-Espinosa, Delcia Rivas, Michael Emig, Juanita Lopez
Journal: Clinical Cancer Research
Clin Cancer Res OF1–OF11.
https://doi.org/10.1158/1078-0432.CCR-24-1991
Published: 27 February 2025
View article titled, First-in-Human Phase I Study of a CD16A Bispecific Innate Cell Engager, AFM24, Targeting EGFR-Expressing Solid Tumors
Open the PDF for First-in-Human Phase I Study of a CD16A Bispecific Innate Cell Engager, AFM24, Targeting EGFR-Expressing Solid Tumors in another window
Includes: Supplementary data
Journal Articles

Memory-like Differentiation, Tumor-Targeting mAbs, and Chimeric Antigen Receptors Enhance Natural Killer Cell Responses to Head and Neck Cancer

Miriam T. Jacobs, Pamela Wong, Alice Y. Zhou, Michelle Becker-Hapak, Nancy D. Marin, Lynne Marsala, Mark Foster, Jennifer A. Foltz, Celia C. Cubitt, Jennifer Tran, David A. Russler-Germain, Carly Neal, Samantha Kersting-Schadek, Lily Chang, Timothy Schappe, Patrick Pence, Ethan McClain, Jose P. Zevallos, Jason T. Rich, Randal C. Paniello, Ryan S. Jackson, Patrik Pipkorn, Douglas R. Adkins, Carl J. DeSelm, Melissa M. Berrien-Elliott, Sidharth V. Puram, Todd A. Fehniger
Journal: Clinical Cancer Research
Clin Cancer Res (2023) 29 (20): 4196–4208.
https://doi.org/10.1158/1078-0432.CCR-23-0156
Published: 13 October 2023
View article titled, Memory-like Differentiation, Tumor-Targeting mAbs, and Chimeric Antigen Receptors Enhance Natural Killer Cell Responses to Head and Neck Cancer
Open the PDF for Memory-like Differentiation, Tumor-Targeting mAbs, and Chimeric Antigen Receptors Enhance Natural Killer Cell Responses to Head and Neck Cancer in another window
Includes: Supplementary data
Journal Articles

Memory-like Differentiation Enhances NK Cell Responses to Melanoma

Nancy D. Marin, Bradley A. Krasnick, Michelle Becker-Hapak, Leah Conant, Simon P. Goedegebuure, Melissa M. Berrien-Elliott, Keenan J. Robbins, Jennifer A. Foltz, Mark Foster, Pamela Wong, Celia C. Cubitt, Jennifer Tran, Christopher B. Wetzel, Miriam Jacobs, Alice Y. Zhou, David Russler-Germain, Lynne Marsala, Timothy Schappe, Ryan C. Fields, Todd A. Fehniger
Journal: Clinical Cancer Research
Clin Cancer Res (2021) 27 (17): 4859–4869.
https://doi.org/10.1158/1078-0432.CCR-21-0851
Published: 01 September 2021
View article titled, Memory-like Differentiation Enhances NK Cell Responses to Melanoma
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Includes: Supplementary data
Journal Articles

Combining AFM13, a Bispecific CD30/CD16 Antibody, with Cytokine-Activated Blood and Cord Blood–Derived NK Cells Facilitates CAR-like Responses Against CD30+ Malignancies

Lucila N. Kerbauy, Nancy D. Marin, Mecit Kaplan, Pinaki P. Banerjee, Melissa M. Berrien-Elliott, Michelle Becker-Hapak, Rafet Basar, Mark Foster, Luciana Garcia Melo, Carly C. Neal, Ethan McClain, May Daher, Ana Karen Nunez Cortes, Sweta Desai, Francesca Wei Inng Lim, Mayela Carolina Mendt, Timothy Schappe, Li Li, Hila Shaim, Mayra Shanley, Emily L. Ensley, Nadima Uprety, Pamela Wong, Enli Liu, Sonny O. Ang, Rong Cai, Vandana Nandivada, Vakul Mohanty, Qi Miao, Yifei Shen, Natalia Baran, Natalie W. Fowlkes, Ken Chen, Luis Muniz-Feliciano, Richard E. Champlin, Yago L. Nieto, Joachim Koch, Martin Treder, Wolfgang Fischer, Oswaldo Keith Okamoto, Elizabeth J. Shpall, Todd A. Fehniger, Katayoun Rezvani
Journal: Clinical Cancer Research
Clin Cancer Res (2021) 27 (13): 3744–3756.
https://doi.org/10.1158/1078-0432.CCR-21-0164
Published: 01 July 2021
View article titled, Combining AFM13, a Bispecific CD30/CD16 Antibody, with Cytokine-Activated Blood and Cord Blood–Derived NK Cells Facilitates CAR-like Responses Against CD30<sup>+</sup> Malignancies
Open the PDF for Combining AFM13, a Bispecific CD30/CD16 Antibody, with Cytokine-Activated Blood and Cord Blood–Derived NK Cells Facilitates CAR-like Responses Against CD30<sup>+</sup> Malignancies in another window
Includes: Supplementary data
Journal Articles

Phase I Trial of N-803, an IL15 Receptor Agonist, with Rituximab in Patients with Indolent Non-Hodgkin Lymphoma

Jennifer A. Foltz, Brian T. Hess, Veronika Bachanova, Nancy L. Bartlett, Melissa M. Berrien-Elliott, Ethan McClain, Michelle Becker-Hapak, Mark Foster, Timothy Schappe, Brad Kahl, Neha Mehta-Shah, Amanda F. Cashen, Nancy D. Marin, Kristen McDaniels, Chaz Moreno, Matthew Mosior, Feng Gao, Obi L. Griffith, Malachi Griffith, Julia A. Wagner, Narendranath Epperla, Amy D. Rock, John Lee, Allegra A. Petti, Patrick Soon-Shiong, Todd A. Fehniger
Journal: Clinical Cancer Research
Clin Cancer Res (2021) 27 (12): 3339–3350.
https://doi.org/10.1158/1078-0432.CCR-20-4575
Published: 15 June 2021
View article titled, Phase I Trial of N-803, an IL15 Receptor Agonist, with Rituximab in Patients with Indolent Non-Hodgkin Lymphoma
Open the PDF for Phase I Trial of N-803, an IL15 Receptor Agonist, with Rituximab in Patients with Indolent Non-Hodgkin Lymphoma in another window
Includes: Supplementary data
Journal Articles

Abstract B12: Complete characterization of the “microRNAome” of a human acute myeloid leukemia

Giridharan Ramsingh, Daniel C. Koboldt, Maria Trissal, Katherine B. Chiappinelli, Todd Wylie, Sunita Koul, Li-Wei Chang, Rakesh Nagarajan, Todd A. Fehniger, Paul Goodfellow, Vincent Magrini, Richard K. Wilson, Li Ding, Timothy J. Ley, Elaine R. Mardis, Daniel C. Link
Journal: Clinical Cancer Research
Clin Cancer Res (2010) 16 (14_Supplement): B12.
https://doi.org/10.1158/1078-0432.TCMUSA10-B12
Published: 02 February 2016
View article titled, Abstract B12: Complete characterization of the “microRNAome” of a human acute myeloid leukemia
Journal Articles

The IL-15-Based ALT-803 Complex Enhances FcγRIIIa-Triggered NK Cell Responses and In Vivo Clearance of B Cell Lymphomas

Maximillian Rosario, Bai Liu, Lin Kong, Lynne I. Collins, Stephanie E. Schneider, Xiaoyue Chen, Kaiping Han, Emily K. Jeng, Peter R. Rhode, Jeffrey W. Leong, Timothy Schappe, Brea A. Jewell, Catherine R. Keppel, Keval Shah, Brian Hess, Rizwan Romee, David R. Piwnica-Worms, Amanda F. Cashen, Nancy L. Bartlett, Hing C. Wong, Todd A. Fehniger
Journal: Clinical Cancer Research
Clin Cancer Res (2016) 22 (3): 596–608.
https://doi.org/10.1158/1078-0432.CCR-15-1419
Published: 31 January 2016
View article titled, The IL-15-Based ALT-803 Complex Enhances FcγRIIIa-Triggered NK Cell Responses and <em>In Vivo</em> Clearance of B Cell Lymphomas
Open the PDF for The IL-15-Based ALT-803 Complex Enhances FcγRIIIa-Triggered NK Cell Responses and <em>In Vivo</em> Clearance of B Cell Lymphomas in another window
Includes: Supplementary data