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Tjalling Bosse
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Journal Articles

Abstract IA014: Personalized adjuvant treatment in endometrial cancer

Tjalling Bosse
Journal: Clinical Cancer Research
Clin Cancer Res (2024) 30 (5_Supplement): IA014.
https://doi.org/10.1158/1557-3265.ENDO24-IA014
Published: 01 March 2024
View article titled, Abstract IA014: Personalized adjuvant treatment in endometrial cancer
Journal Articles

Clinical Behavior and Molecular Landscape of Stage I p53-Abnormal Low-Grade Endometrioid Endometrial Carcinomas

Amy Jamieson, Lisa Vermij, Claire J.H. Kramer, Jan J. Jobsen, Ina Jürgemlienk-Schulz, Ludy Lutgens, Jan Willem Mens, Marie A.D. Haverkort, Annerie Slot, Remi A. Nout, Jan Oosting, Joseph Carlson, Brooke E. Howitt, Philip P.C. Ip, Sigurd F. Lax, W. Glenn McCluggage, Naveena Singh, Jessica N. McAlpine, Carien L. Creutzberg, Nanda Horeweg, C. Blake Gilks, Tjalling Bosse
Journal: Clinical Cancer Research
Clin Cancer Res (2023) 29 (23): 4949–4957.
https://doi.org/10.1158/1078-0432.CCR-23-1397
Published: 01 December 2023
View article titled, Clinical Behavior and Molecular Landscape of Stage I p53-Abnormal Low-Grade Endometrioid Endometrial Carcinomas
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Includes: Supplementary data
Journal Articles

Abstract IA013: Endometrial carcinomas with a mutation in DNA polymerase epsilon: A pathologist view

Tjalling Bosse
Journal: Clinical Cancer Research
Clin Cancer Res (2021) 27 (3_Supplement): IA013.
https://doi.org/10.1158/1557-3265.ENDOMET20-IA013
Published: 01 February 2021
View article titled, Abstract IA013: Endometrial carcinomas with a mutation in DNA polymerase epsilon: A pathologist view
Journal Articles

Endometrial Cancer Molecular Risk Stratification is Equally Prognostic for Endometrioid Ovarian Carcinoma

Pauline Krämer, Aline Talhouk, Mary Anne Brett, Derek S. Chiu, Evan S. Cairns, Daniëlla A. Scheunhage, Rory F.L. Hammond, David Farnell, Tayyebeh M. Nazeran, Marcel Grube, Zhouchunyang Xia, Janine Senz, Samuel Leung, Lukas Feil, Jana Pasternak, Katherine Dixon, Andreas Hartkopf, Bernhard Krämer, Sara Brucker, Florian Heitz, Andreas du Bois, Philipp Harter, Felix K.F. Kommoss, Hans-Peter Sinn, Sabine Heublein, Friedrich Kommoss, Hans-Walter Vollert, Ranjit Manchanda, Cornelis D. de Kroon, Hans W. Nijman, Marco de Bruyn, Emily F. Thompson, Ali Bashashati, Jessica N. McAlpine, Naveena Singh, Anna V. Tinker, Annette Staebler, Tjalling Bosse, Stefan Kommoss, Martin Köbel, Michael S. Anglesio
Journal: Clinical Cancer Research
Clin Cancer Res (2020) 26 (20): 5400–5410.
https://doi.org/10.1158/1078-0432.CCR-20-1268
Published: 15 October 2020
View article titled, Endometrial Cancer Molecular Risk Stratification is Equally Prognostic for Endometrioid Ovarian Carcinoma
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Includes: Supplementary data
Journal Articles

Abstract B20: Endometrial cancer molecular risk stratification in endometrioid ovarian cancers: A novel application of precision medicine

Pauline Krämer, Aline Talhouk, Tjalling Bosse, Florian Heitz, Naveena Singh, Felix Kommoss, Sara Brucker, Jessica McAlpine, Stefan Kommoss, Martin Koebel, Michael Anglesio
Journal: Clinical Cancer Research
Clin Cancer Res (2020) 26 (13_Supplement): B20.
https://doi.org/10.1158/1557-3265.OVCA19-B20
Published: 01 July 2020
View article titled, Abstract B20: Endometrial cancer molecular risk stratification in endometrioid ovarian cancers: A novel application of precision medicine
Journal Articles

Germline BRCA-Associated Endometrial Carcinoma Is a Distinct Clinicopathologic Entity

Marthe M. de Jonge, Lauren L. Ritterhouse, Cornelis D. de Kroon, Maaike P.G. Vreeswijk, Jeremy P. Segal, Rutika Puranik, Harry Hollema, Matti A. Rookus, Christi J. van Asperen, Flora E. van Leeuwen, Vincent T.H.B.M. Smit, Brooke E. Howitt, Tjalling Bosse
Journal: Clinical Cancer Research
Series: Author Choice
Clin Cancer Res (2019) 25 (24): 7517–7526.
https://doi.org/10.1158/1078-0432.CCR-19-0848
Published: 13 December 2019
View article titled, Germline <em>BRCA</em>-Associated Endometrial Carcinoma Is a Distinct Clinicopathologic Entity
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Includes: Supplementary data
Journal Articles

Integrated Molecular Analysis of Undifferentiated Uterine Sarcomas Reveals Clinically Relevant Molecular Subtypes

Amrei Binzer-Panchal, Elin Hardell, Björn Viklund, Mehran Ghaderi, Tjalling Bosse, Marisa R. Nucci, Cheng-Han Lee, Nina Hollfelder, Pádraic Corcoran, Jordi Gonzalez-Molina, Lidia Moyano-Galceran, Debra A. Bell, John K. Schoolmeester, Anna Måsbäck, Gunnar B. Kristensen, Ben Davidson, Kaisa Lehti, Anders Isaksson, Joseph W. Carlson
Journal: Clinical Cancer Research
Series: Author Choice
Clin Cancer Res (2019) 25 (7): 2155–2165.
https://doi.org/10.1158/1078-0432.CCR-18-2792
Published: 01 April 2019
View article titled, Integrated Molecular Analysis of Undifferentiated Uterine Sarcomas Reveals Clinically Relevant Molecular Subtypes
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Includes: Supplementary data
Journal Articles

Frequent Homologous Recombination Deficiency in High-grade Endometrial Carcinomas

Marthe M. de Jonge, Aurélie Auguste, Lise M. van Wijk, Philip C. Schouten, Matty Meijers, Natalja T. ter Haar, Vincent T.H.B.M. Smit, Remi A. Nout, Mark A. Glaire, David N. Church, Harry Vrieling, Bastien Job, Yannick Boursin, Cor D. de Kroon, Etienne Rouleau, Alexandra Leary, Maaike P.G. Vreeswijk, Tjalling Bosse
Journal: Clinical Cancer Research
Series: Author Choice
Clin Cancer Res (2019) 25 (3): 1087–1097.
https://doi.org/10.1158/1078-0432.CCR-18-1443
Published: 01 February 2019
View article titled, Frequent Homologous Recombination Deficiency in High-grade Endometrial Carcinomas
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Includes: Supplementary data
Journal Articles

Adjuvant Treatment for POLE Proofreading Domain–Mutant Cancers: Sensitivity to Radiotherapy, Chemotherapy, and Nucleoside Analogues

Inge C. Van Gool, Emily Rayner, Elisabeth M. Osse, Remi A. Nout, Carien L. Creutzberg, Ian P.M. Tomlinson, David N. Church, Vincent T.H.B.M. Smit, Niels de Wind, Tjalling Bosse, Mark Drost
Journal: Clinical Cancer Research
Clin Cancer Res (2018) 24 (13): 3197–3203.
https://doi.org/10.1158/1078-0432.CCR-18-0266
Published: 01 July 2018
View article titled, Adjuvant Treatment for <em>POLE</em> Proofreading Domain–Mutant Cancers: Sensitivity to Radiotherapy, Chemotherapy, and Nucleoside Analogues
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Includes: Supplementary data
Journal Articles

Amplification of 1q32.1 Refines the Molecular Classification of Endometrial Carcinoma

Jeroen Depreeuw, Ellen Stelloo, Elisabeth M. Osse, Carien L. Creutzberg, Remi A. Nout, Matthieu Moisse, Diego A. Garcia-Dios, Michael Dewaele, Karen Willekens, Jean-Christophe Marine, Xavier Matias-Guiu, Frédéric Amant, Diether Lambrechts, Tjalling Bosse
Journal: Clinical Cancer Research
Clin Cancer Res (2017) 23 (23): 7232–7241.
https://doi.org/10.1158/1078-0432.CCR-17-0566
Published: 30 November 2017
View article titled, Amplification of 1q32.1 Refines the Molecular Classification of Endometrial Carcinoma
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Includes: Supplementary data
Journal Articles

Genomic Characterization of Vulvar (Pre)cancers Identifies Distinct Molecular Subtypes with Prognostic Significance

Linda S. Nooij, Natalja T. ter Haar, Dina Ruano, Natalia Rakislova, Tom van Wezel, Vincent T.H.B.M. Smit, Baptist J.B.M.Z. Trimbos, Jaume Ordi, Mariette I.E. van Poelgeest, Tjalling Bosse
Journal: Clinical Cancer Research
Series: Author Choice
Clin Cancer Res (2017) 23 (22): 6781–6789.
https://doi.org/10.1158/1078-0432.CCR-17-1302
Published: 14 November 2017
View article titled, Genomic Characterization of Vulvar (Pre)cancers Identifies Distinct Molecular Subtypes with Prognostic Significance
Open the PDF for Genomic Characterization of Vulvar (Pre)cancers Identifies Distinct Molecular Subtypes with Prognostic Significance in another window
Includes: Supplementary data
Journal Articles

Potential Targets' Analysis Reveals Dual PI3K/mTOR Pathway Inhibition as a Promising Therapeutic Strategy for Uterine Leiomyosarcomas—an ENITEC Group Initiative

Tine Cuppens, Daniela Annibali, An Coosemans, Jone Trovik, Natalja ter Haar, Eva Colas, Angel Garcia-Jimenez, Koen Van de Vijver, Roy P.M. Kruitwagen, Mariël Brinkhuis, Michal Zikan, Pavel Dundr, Jutta Huvila, Olli Carpén, Johannes Haybaeck, Farid Moinfar, Helga B. Salvesen, Maciej Stukan, Carole Mestdagh, Ronald P. Zweemer, Leonardus F. Massuger, Michael R. Mallmann, Eva Wardelmann, Miriam Mints, Godelieve Verbist, Debby Thomas, Ellen Gommé, Els Hermans, Philippe Moerman, Tjalling Bosse, Frédéric Amant
Journal: Clinical Cancer Research
Clin Cancer Res (2017) 23 (5): 1274–1285.
https://doi.org/10.1158/1078-0432.CCR-16-2149
Published: 28 February 2017
View article titled, Potential Targets' Analysis Reveals Dual PI3K/mTOR Pathway Inhibition as a Promising Therapeutic Strategy for Uterine Leiomyosarcomas—an ENITEC Group Initiative
Open the PDF for Potential Targets' Analysis Reveals Dual PI3K/mTOR Pathway Inhibition as a Promising Therapeutic Strategy for Uterine Leiomyosarcomas—an ENITEC Group Initiative in another window
Includes: Supplementary data
Journal Articles

Noninvasive Detection of Metastases and Follicle Density in Ovarian Tissue Using Full-Field Optical Coherence Tomography

Inge T.A. Peters, Paulien L. Stegehuis, Ronald Peek, Florine L. Boer, Erik W. van Zwet, Jeroen Eggermont, Johan R. Westphal, Peter J.K. Kuppen, J. Baptist Trimbos, Carina G.J.M. Hilders, Boudewijn P.F. Lelieveldt, Cornelis J.H. van de Velde, Tjalling Bosse, Jouke Dijkstra, Alexander L. Vahrmeijer
Journal: Clinical Cancer Research
Clin Cancer Res (2016) 22 (22): 5506–5513.
https://doi.org/10.1158/1078-0432.CCR-16-0288
Published: 14 November 2016
View article titled, Noninvasive Detection of Metastases and Follicle Density in Ovarian Tissue Using Full-Field Optical Coherence Tomography
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Includes: Supplementary data
Journal Articles

Loss of ARID1A Activates ANXA1, which Serves as a Predictive Biomarker for Trastuzumab Resistance

Katrien Berns, Amir Sonnenblick, Annemiek Gennissen, Sylvain Brohée, E. Marielle Hijmans, Bastiaan Evers, Debora Fumagalli, Christine Desmedt, Sibylle Loibl, Carsten Denkert, Patrick Neven, Wei Guo, Fan Zhang, Theo A. Knijnenburg, Tjalling Bosse, Michiel S. van der Heijden, Sanne Hindriksen, Wouter Nijkamp, Lodewyk F.A. Wessels, Heikki Joensuu, Gordon B. Mills, Roderick L. Beijersbergen, Christos Sotiriou, René Bernards
Journal: Clinical Cancer Research
Clin Cancer Res (2016) 22 (21): 5238–5248.
https://doi.org/10.1158/1078-0432.CCR-15-2996
Published: 31 October 2016
View article titled, Loss of <em>ARID1A</em> Activates <em>ANXA1</em>, which Serves as a Predictive Biomarker for Trastuzumab Resistance
Open the PDF for Loss of <em>ARID1A</em> Activates <em>ANXA1</em>, which Serves as a Predictive Biomarker for Trastuzumab Resistance in another window
Includes: Supplementary data
Journal Articles

Improved Risk Assessment by Integrating Molecular and Clinicopathological Factors in Early-stage Endometrial Cancer—Combined Analysis of the PORTEC Cohorts

Ellen Stelloo, Remi A. Nout, Elisabeth M. Osse, Ina J. Jürgenliemk-Schulz, Jan J. Jobsen, Ludy C. Lutgens, Elzbieta M. van der Steen-Banasik, Hans W. Nijman, Hein Putter, Tjalling Bosse, Carien L. Creutzberg, Vincent T.H.B.M. Smit
Journal: Clinical Cancer Research
Clin Cancer Res (2016) 22 (16): 4215–4224.
https://doi.org/10.1158/1078-0432.CCR-15-2878
Published: 14 August 2016
View article titled, Improved Risk Assessment by Integrating Molecular and Clinicopathological Factors in Early-stage Endometrial Cancer—Combined Analysis of the PORTEC Cohorts
Open the PDF for Improved Risk Assessment by Integrating Molecular and Clinicopathological Factors in Early-stage Endometrial Cancer—Combined Analysis of the PORTEC Cohorts in another window
Includes: Supplementary data
Journal Articles

A Novel Tumor-Specific Agent for Intraoperative Near-Infrared Fluorescence Imaging: A Translational Study in Healthy Volunteers and Patients with Ovarian Cancer

Charlotte E.S. Hoogstins, Quirijn R.J.G. Tummers, Katja N. Gaarenstroom, Cor D. de Kroon, J. Baptist M.Z. Trimbos, Tjalling Bosse, Vincent T.H.B.M. Smit, Jaap Vuyk, Cornelis J.H. van de Velde, Adam F. Cohen, Philip S. Low, Jacobus Burggraaf, Alexander L. Vahrmeijer
Journal: Clinical Cancer Research
Series: Author Choice
Clin Cancer Res (2016) 22 (12): 2929–2938.
https://doi.org/10.1158/1078-0432.CCR-15-2640
Published: 14 June 2016
View article titled, A Novel Tumor-Specific Agent for Intraoperative Near-Infrared Fluorescence Imaging: A Translational Study in Healthy Volunteers and Patients with Ovarian Cancer
Open the PDF for A Novel Tumor-Specific Agent for Intraoperative Near-Infrared Fluorescence Imaging: A Translational Study in Healthy Volunteers and Patients with Ovarian Cancer in another window
Includes: Multimedia, Supplementary data
Journal Articles

Vaccination against Oncoproteins of HPV16 for Noninvasive Vulvar/Vaginal Lesions: Lesion Clearance Is Related to the Strength of the T-Cell Response

Mariëtte I.E. van Poelgeest, Marij J.P. Welters, Renee Vermeij, Linda F.M. Stynenbosch, Nikki M. Loof, Dorien M.A. Berends-van der Meer, Margriet J.G. Löwik, Ineke L.E. Hamming, Edith M.G. van Esch, Bart W.J. Hellebrekers, Marc van Beurden, Henk W. Schreuder, Marjolein J. Kagie, J. Baptist M.Z. Trimbos, Lorraine M. Fathers, Toos Daemen, Harry Hollema, A. Rob P.M. Valentijn, Jaap Oostendorp, J. Hanneke N.G. Oude Elberink, Gertjan J. Fleuren, Tjalling Bosse, Gemma G. Kenter, Theo Stijnen, Hans W. Nijman, Cornelis J.M. Melief, Sjoerd H. van der Burg
Journal: Clinical Cancer Research
Clin Cancer Res (2016) 22 (10): 2342–2350.
https://doi.org/10.1158/1078-0432.CCR-15-2594
Published: 12 May 2016
View article titled, Vaccination against Oncoproteins of HPV16 for Noninvasive Vulvar/Vaginal Lesions: Lesion Clearance Is Related to the Strength of the T-Cell Response
Open the PDF for Vaccination against Oncoproteins of HPV16 for Noninvasive Vulvar/Vaginal Lesions: Lesion Clearance Is Related to the Strength of the T-Cell Response in another window
Includes: Supplementary data
Journal Articles

POLE Proofreading Mutations Elicit an Antitumor Immune Response in Endometrial Cancer

Inge C. van Gool, Florine A. Eggink, Luke Freeman-Mills, Ellen Stelloo, Emanuele Marchi, Marco de Bruyn, Claire Palles, Remi A. Nout, Cor D. de Kroon, Elisabeth M. Osse, Paul Klenerman, Carien L. Creutzberg, Ian P.M. Tomlinson, Vincent T.H.B.M. Smit, Hans W. Nijman, Tjalling Bosse, David N. Church
Journal: Clinical Cancer Research
Series: Author Choice
Clin Cancer Res (2015) 21 (14): 3347–3355.
https://doi.org/10.1158/1078-0432.CCR-15-0057
Published: 14 July 2015
View article titled, <em>POLE</em> Proofreading Mutations Elicit an Antitumor Immune Response in Endometrial Cancer
Open the PDF for <em>POLE</em> Proofreading Mutations Elicit an Antitumor Immune Response in Endometrial Cancer in another window
Includes: Supplementary data