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Timothy S. Maughan
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Journal Articles

In-depth Clinical and Biological Exploration of DNA Damage Immune Response as a Biomarker for Oxaliplatin Use in Colorectal Cancer

Sudhir B. Malla, David J. Fisher, Enric Domingo, Andrew Blake, Sylvana Hassanieh, Keara L. Redmond, Susan D. Richman, Michael Youdell, Steven M. Walker, Gemma E. Logan, Aikaterina Chatzipli, Raheleh Amirkhah, Matthew P. Humphries, Stephanie G. Craig, Ultan McDermott, Matthew T. Seymour, Dion G. Morton, Philip Quirke, Nicholas P. West, Manuel Salto-Tellez, Richard D. Kennedy, Patrick G. Johnston, Ian Tomlinson, Viktor H. Koelzer, Letitia Campo, Richard S. Kaplan, Daniel B. Longley, Mark Lawler, Timothy S. Maughan, Louise C. Brown, Philip D. Dunne
Journal: Clinical Cancer Research
Series: Author Choice
Clin Cancer Res (2021) 27 (1): 288–300.
https://doi.org/10.1158/1078-0432.CCR-20-3237
Published: 04 January 2021
View article titled, In-depth Clinical and Biological Exploration of DNA Damage Immune Response as a Biomarker for Oxaliplatin Use in Colorectal Cancer
Open the PDF for In-depth Clinical and Biological Exploration of DNA Damage Immune Response as a Biomarker for Oxaliplatin Use in Colorectal Cancer in another window
Includes: Supplementary data
Journal Articles

The Interleukin 22 Pathway Interacts with Mutant KRAS to Promote Poor Prognosis in Colon Cancer

Sarah McCuaig, David Barras, Elizabeth H. Mann, Matthias Friedrich, Samuel J. Bullers, Alina Janney, Lucy C. Garner, Enric Domingo, Viktor Hendrik Koelzer, Mauro Delorenzi, Sabine Tejpar, Timothy S. Maughan, Nathaniel R. West, Fiona Powrie
Journal: Clinical Cancer Research
Clin Cancer Res (2020) 26 (16): 4313–4325.
https://doi.org/10.1158/1078-0432.CCR-19-1086
Published: 14 August 2020
View article titled, The Interleukin 22 Pathway Interacts with Mutant KRAS to Promote Poor Prognosis in Colon Cancer
Open the PDF for The Interleukin 22 Pathway Interacts with Mutant KRAS to Promote Poor Prognosis in Colon Cancer in another window
Includes: Supplementary data
Journal Articles

BRAF and NRAS Locus-Specific Variants Have Different Outcomes on Survival to Colorectal Cancer

Matthew G. Summers, Christopher G. Smith, Timothy S. Maughan, Richard Kaplan, Valentina Escott-Price, Jeremy P. Cheadle
Journal: Clinical Cancer Research
Clin Cancer Res (2017) 23 (11): 2742–2749.
https://doi.org/10.1158/1078-0432.CCR-16-1541
Published: 31 May 2017
View article titled, <em>BRAF</em> and <em>NRAS</em> Locus-Specific Variants Have Different Outcomes on Survival to Colorectal Cancer
Open the PDF for <em>BRAF</em> and <em>NRAS</em> Locus-Specific Variants Have Different Outcomes on Survival to Colorectal Cancer in another window
Includes: Supplementary data
Journal Articles

Analyses of 7,635 Patients with Colorectal Cancer Using Independent Training and Validation Cohorts Show That rs9929218 in CDH1 Is a Prognostic Marker of Survival

Christopher G. Smith, David Fisher, Rebecca Harris, Timothy S. Maughan, Amanda I. Phipps, Susan Richman, Matthew Seymour, Ian Tomlinson, Dan Rosmarin, David Kerr, Andrew T. Chan, Ulrike Peters, Polly A. Newcomb, Shelley Idziaszczyk, Hannah West, Angela Meade, Richard Kaplan, Jeremy P. Cheadle
Journal: Clinical Cancer Research
Clin Cancer Res (2015) 21 (15): 3453–3461.
https://doi.org/10.1158/1078-0432.CCR-14-3136
Published: 02 August 2015
View article titled, Analyses of 7,635 Patients with Colorectal Cancer Using Independent Training and Validation Cohorts Show That rs9929218 in <em>CDH1</em> Is a Prognostic Marker of Survival
Open the PDF for Analyses of 7,635 Patients with Colorectal Cancer Using Independent Training and Validation Cohorts Show That rs9929218 in <em>CDH1</em> Is a Prognostic Marker of Survival in another window
Includes: Supplementary data
Journal Articles

Somatic Profiling of the Epidermal Growth Factor Receptor Pathway in Tumors from Patients with Advanced Colorectal Cancer Treated with Chemotherapy ± Cetuximab

Christopher G. Smith, David Fisher, Bart Claes, Timothy S. Maughan, Shelley Idziaszczyk, Gilian Peuteman, Rebecca Harris, Michelle D. James, Angela Meade, Bharat Jasani, Richard A. Adams, Sarah Kenny, Richard Kaplan, Diether Lambrechts, Jeremy P. Cheadle
Journal: Clinical Cancer Research
Clin Cancer Res (2013) 19 (15): 4104–4113.
https://doi.org/10.1158/1078-0432.CCR-12-2581
Published: 31 July 2013
View article titled, Somatic Profiling of the Epidermal Growth Factor Receptor Pathway in Tumors from Patients with Advanced Colorectal Cancer Treated with Chemotherapy ± Cetuximab
Open the PDF for Somatic Profiling of the Epidermal Growth Factor Receptor Pathway in Tumors from Patients with Advanced Colorectal Cancer Treated with Chemotherapy ± Cetuximab in another window
Includes: Supplementary data