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Tibor Keler
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Journal Articles

Clinical and Translational Results from PORTER, a Multicohort Phase I Platform Trial of Combination Immunotherapy in Metastatic Castration-Resistant Prostate Cancer

Matthew D. Galsky, Karen A. Autio, Christopher R. Cabanski, Kristopher Wentzel, Julie N. Graff, Terence W. Friedlander, Timothy R. Howes, Kristin M. Shotts, Julie Densmore, Marko Spasic, Diane M. Da Silva, Richard O. Chen, Jennifer Lata, Jeffrey Skolnik, Tibor Keler, Michael J. Yellin, Theresa M. LaVallee, Justin Fairchild, Silvia Boffo, Jill O’Donnell-Tormey, Ute Dugan, Nina Bhardwaj, Sumit K. Subudhi, Lawrence Fong
Journal: Clinical Cancer Research
Clin Cancer Res OF1–OF13.
https://doi.org/10.1158/1078-0432.CCR-24-3693
Published: 18 March 2025
View article titled, Clinical and Translational Results from PORTER, a Multicohort Phase I Platform Trial of Combination Immunotherapy in Metastatic Castration-Resistant Prostate Cancer
Open the PDF for Clinical and Translational Results from PORTER, a Multicohort Phase I Platform Trial of Combination Immunotherapy in Metastatic Castration-Resistant Prostate Cancer in another window
Includes: Supplementary data
Journal Articles

Rindopepimut with Bevacizumab for Patients with Relapsed EGFRvIII-Expressing Glioblastoma (ReACT): Results of a Double-Blind Randomized Phase II Trial

David A. Reardon, Annick Desjardins, James J. Vredenburgh, Donald M. O'Rourke, David D. Tran, Karen L. Fink, Louis B. Nabors, Gordon Li, Daniela A. Bota, Rimas V. Lukas, Lynn S. Ashby, J. Paul Duic, Maciej M. Mrugala, Scott Cruickshank, Laura Vitale, Yi He, Jennifer A. Green, Michael J. Yellin, Christopher D. Turner, Tibor Keler, Thomas A. Davis, John H. Sampson
Journal: Clinical Cancer Research
Clin Cancer Res (2020) 26 (7): 1586–1594.
https://doi.org/10.1158/1078-0432.CCR-18-1140
Published: 01 April 2020
View article titled, Rindopepimut with Bevacizumab for Patients with Relapsed EGFRvIII-Expressing Glioblastoma (ReACT): Results of a Double-Blind Randomized Phase II Trial
Open the PDF for Rindopepimut with Bevacizumab for Patients with Relapsed EGFRvIII-Expressing Glioblastoma (ReACT): Results of a Double-Blind Randomized Phase II Trial in another window
Includes: Supplementary data
Journal Articles

PD-1 Blockade and CD27 Stimulation Activate Distinct Transcriptional Programs That Synergize for CD8+ T-Cell–Driven Antitumor Immunity

Sarah L. Buchan, Mohannad Fallatah, Stephen M. Thirdborough, Vadim Y. Taraban, Anne Rogel, Lawrence J. Thomas, Christine A. Penfold, Li-Zhen He, Michael A. Curran, Tibor Keler, Aymen Al-Shamkhani
Journal: Clinical Cancer Research
Clin Cancer Res (2018) 24 (10): 2383–2394.
https://doi.org/10.1158/1078-0432.CCR-17-3057
Published: 14 May 2018
View article titled, PD-1 Blockade and CD27 Stimulation Activate Distinct Transcriptional Programs That Synergize for CD8<sup>+</sup> T-Cell–Driven Antitumor Immunity
Open the PDF for PD-1 Blockade and CD27 Stimulation Activate Distinct Transcriptional Programs That Synergize for CD8<sup>+</sup> T-Cell–Driven Antitumor Immunity in another window
Includes: Supplementary data
Journal Articles

MAPK Pathway Inhibitors Sensitize BRAF-Mutant Melanoma to an Antibody-Drug Conjugate Targeting GPNMB

April A.N. Rose, Matthew G. Annis, Dennie T. Frederick, Marco Biondini, Zhifeng Dong, Lawrence Kwong, Lynda Chin, Tibor Keler, Thomas Hawthorne, Ian R. Watson, Keith T. Flaherty, Peter M. Siegel
Journal: Clinical Cancer Research
Clin Cancer Res (2016) 22 (24): 6088–6098.
https://doi.org/10.1158/1078-0432.CCR-16-1192
Published: 15 December 2016
View article titled, MAPK Pathway Inhibitors Sensitize BRAF-Mutant Melanoma to an Antibody-Drug Conjugate Targeting GPNMB
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Includes: Supplementary data
Journal Articles

Development of a Human Monoclonal Antibody for Potential Therapy of CD27-Expressing Lymphoma and Leukemia

Laura A. Vitale, Li-Zhen He, Lawrence J. Thomas, Jennifer Widger, Jeffrey Weidlick, Andrea Crocker, Thomas O'Neill, James Storey, Martin J. Glennie, Deanna M. Grote, Stephen M. Ansell, Henry Marsh, Tibor Keler
Journal: Clinical Cancer Research
Clin Cancer Res (2012) 18 (14): 3812–3821.
https://doi.org/10.1158/1078-0432.CCR-11-3308
Published: 15 July 2012
View article titled, Development of a Human Monoclonal Antibody for Potential Therapy of CD27-Expressing Lymphoma and Leukemia
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Journal Articles

Phase I Study Utilizing a Novel Antigen-Presenting Cell–Targeted Vaccine with Toll-like Receptor Stimulation to Induce Immunity to Self-antigens in Cancer Patients

Michael A. Morse, Robert Chapman, John Powderly, Kimberly Blackwell, Tibor Keler, Jennifer Green, Renee Riggs, Li-Zhen He, Venky Ramakrishna, Laura Vitale, Biwei Zhao, Stephen A. Butler, Amy Hobeika, Takuya Osada, Thomas Davis, Timothy Clay, H. Kim Lyerly
Journal: Clinical Cancer Research
Clin Cancer Res (2011) 17 (14): 4844–4853.
https://doi.org/10.1158/1078-0432.CCR-11-0891
Published: 17 July 2011
View article titled, Phase I Study Utilizing a Novel Antigen-Presenting Cell–Targeted Vaccine with Toll-like Receptor Stimulation to Induce Immunity to Self-antigens in Cancer Patients
Open the PDF for Phase I Study Utilizing a Novel Antigen-Presenting Cell–Targeted Vaccine with Toll-like Receptor Stimulation to Induce Immunity to Self-antigens in Cancer Patients in another window
Includes: Supplementary data
Journal Articles

A Novel Human Cancer Vaccine Elicits Cellular Responses to the Tumor-Associated Antigen, Human Chorionic Gonadotropin β

Li-Zhen He, Venky Ramakrishna, John E. Connolly, Xi-Tao Wang, Patricia A. Smith, Charles L. Jones, Maria Valkova-Valchanova, Alahari Arunakumari, John F. Treml, Joel Goldstein, Paul K. Wallace, Tibor Keler, Michael J. Endres
Journal: Clinical Cancer Research
Clin Cancer Res (2004) 10 (6): 1920–1927.
https://doi.org/10.1158/1078-0432.CCR-03-0264
Published: 24 March 2004
View article titled, A Novel Human Cancer Vaccine Elicits Cellular Responses to the Tumor-Associated Antigen, Human Chorionic Gonadotropin β
Open the PDF for A Novel Human Cancer Vaccine Elicits Cellular Responses to the Tumor-Associated Antigen, Human Chorionic Gonadotropin β in another window