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Theodore S. Lawrence
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Journal Articles

A Phase II Study of Optimized Individualized Adaptive Radiotherapy for Hepatocellular Carcinoma

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Daniel J. Herr, Chang Wang, Mishal Mendiratta-Lala, Martha Matuszak, Charles S. Mayo, Yue Cao, Neehar D. Parikh, Randy Ten Haken, Dawn Owen, Joseph R. Evans, Teodor Stanescu, Michael Yan, Laura A. Dawson, Matthew Schipper, Theodore S. Lawrence, Kyle C. Cuneo
Journal: Clinical Cancer Research
Clin Cancer Res (2023) 29 (19): 3852–3858.
https://doi.org/10.1158/1078-0432.CCR-23-1044
Published: 02 October 2023
View articletitled, A Phase II Study of Optimized Individualized Adaptive Radiotherapy for Hepatocellular Carcinoma
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Includes: Supplementary data
Journal Articles

Randomized Phase II Study of Physiologic MRI-Directed Adaptive Radiation Boost in Poor Prognosis Head and Neck Cancer

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Michelle L. Mierzwa, Madhava Aryal, Choonik Lee, Matthew Schipper, Monica VanTil, Krystal Morales, Paul L. Swiecicki, Keith A. Casper, Kelly M. Malloy, Matthew E. Spector, Andrew G. Shuman, Steven B. Chinn, Mark E.P. Prince, Chaz L. Stucken, Andrew J. Rosko, Theodore S. Lawrence, J. Chad Brenner, Benjamin Rosen, Caitlin A. Schonewolf, Jennifer Shah, Avraham Eisbruch, Francis P. Worden, Yue Cao
Journal: Clinical Cancer Research
Clin Cancer Res (2022) 28 (23): 5049–5057.
https://doi.org/10.1158/1078-0432.CCR-22-1522
Published: 01 December 2022
View articletitled, Randomized Phase II Study of Physiologic MRI-Directed Adaptive Radiation Boost in Poor Prognosis Head and Neck Cancer
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Includes: Supplementary data
Journal Articles

Abstract PO-008: Mechanistic and therapeutic links between purine biosynthesis and DNA damage in glioblastoma

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Andrew J. Scott, Weihua Zhou, Kari Wilder-Romans, Anthony C. Andren, Li Zhang, Yoshie Umemura, Nathan Qi, Theodore S. Lawrence, Costas A. Lyssiotis, Daniel R Wahl
Journal: Clinical Cancer Research
Clin Cancer Res (2021) 27 (8_Supplement): PO-008.
https://doi.org/10.1158/1557-3265.RADSCI21-PO-008
Published: 15 April 2021
View articletitled, Abstract PO-008: Mechanistic and therapeutic links between purine biosynthesis and DNA damage in glioblastoma
Journal Articles

Abstract PR-004: Radiation modulates hepatic siphoning of T cells to improve immunotherapy efficacy

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Michael Green, Jiali Yu, Shasha Li, Theodore S. Lawrence, Weiping Zou
Journal: Clinical Cancer Research
Clin Cancer Res (2021) 27 (8_Supplement): PR-004.
https://doi.org/10.1158/1557-3265.RADSCI21-PR-004
Published: 15 April 2021
View articletitled, Abstract PR-004: Radiation modulates hepatic siphoning of T cells to improve immunotherapy efficacy
Journal Articles

Drug–Radiotherapy Combination Trial Developments—Letter

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Joseph R. Evans, Kyle C. Cuneo, Theodore S. Lawrence
Journal: Clinical Cancer Research
Clin Cancer Res (2021) 27 (1): 355.
https://doi.org/10.1158/1078-0432.CCR-20-4003
Published: 04 January 2021
View articletitled, Drug–Radiotherapy Combination Trial Developments—Letter
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Journal Articles

Low-Dose Hsp90 Inhibitor Selectively Radiosensitizes HNSCC and Pancreatic Xenografts

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Ranjit K. Mehta, Sanjima Pal, Koushik Kondapi, Merna Sitto, Cuyler Dewar, Theresa Devasia, Matthew J. Schipper, Dafydd G. Thomas, Venkatesha Basrur, Manjunath P. Pai, Yoshihiro Morishima, Yoichi Osawa, William B. Pratt, Theodore S. Lawrence, Mukesh K. Nyati
Journal: Clinical Cancer Research
Clin Cancer Res (2020) 26 (19): 5246–5257.
https://doi.org/10.1158/1078-0432.CCR-19-3102
Published: 01 October 2020
View articletitled, Low-Dose Hsp90 Inhibitor Selectively Radiosensitizes HNSCC and Pancreatic Xenografts
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Includes: Supplementary data
Journal Articles

Clinical Development of Novel Drug–Radiotherapy Combinations

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Saif S. Ahmad, Marka R. Crittenden, Phuoc T. Tran, Paul G. Kluetz, Gideon M. Blumenthal, Helen Bulbeck, Richard D. Baird, Kaye J. Williams, Tim Illidge, Stephen M. Hahn, Theodore S. Lawrence, Patricia A. Spears, Amanda J. Walker, Ricky A. Sharma
Journal: Clinical Cancer Research
Clin Cancer Res (2019) 25 (5): 1455–1461.
https://doi.org/10.1158/1078-0432.CCR-18-2466
Published: 01 March 2019
View articletitled, Clinical Development of Novel Drug–Radiotherapy Combinations
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Journal Articles

No Sugar Added: A New Strategy to Inhibit Glioblastoma Receptor Tyrosine Kinases

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Daniel R. Wahl, Theodore S. Lawrence
Journal: Clinical Cancer Research
Clin Cancer Res (2019) 25 (2): 455–456.
https://doi.org/10.1158/1078-0432.CCR-18-2113
Published: 15 January 2019
View articletitled, No Sugar Added: A New Strategy to Inhibit Glioblastoma Receptor Tyrosine Kinases
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Journal Articles

Maternal Embryonic Leucine Zipper Kinase (MELK) as a Novel Mediator and Biomarker of Radioresistance in Human Breast Cancer

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Corey Speers, Shuang G. Zhao, Vishal Kothari, Alyssa Santola, Meilan Liu, Kari Wilder-Romans, Joseph Evans, Nidhi Batra, Harry Bartelink, Daniel F. Hayes, Theodore S. Lawrence, Powel H. Brown, Lori J. Pierce, Felix Y. Feng
Journal: Clinical Cancer Research
Series: Author Choice
Clin Cancer Res (2016) 22 (23): 5864–5875.
https://doi.org/10.1158/1078-0432.CCR-15-2711
Published: 30 November 2016
View articletitled, Maternal Embryonic Leucine Zipper Kinase (MELK) as a Novel Mediator and Biomarker of Radioresistance in Human Breast Cancer
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Includes: Supplementary data
Journal Articles

AACR Cancer Progress Report 2015

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José Baselga, Nina Bhardwaj, Lewis C. Cantley, Ronald DeMatteo, Raymond N. DuBois, Margaret Foti, Susan M. Gapstur, William C. Hahn, Lee J. Helman, Roy A. Jensen, Electra D. Paskett, Theodore S. Lawrence, Stuart G. Lutzker, Eva Szabo
Journal: Clinical Cancer Research
Clin Cancer Res (2015) 21 (19_Supplement): S1–S128.
https://doi.org/10.1158/1078-0432.CCR-15-1846
Published: 30 September 2015
View articletitled, AACR Cancer Progress Report 2015
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Includes: Supplementary data
Journal Articles

Molecular Pathways: Overcoming Radiation Resistance by Targeting DNA Damage Response Pathways

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Meredith A. Morgan, Theodore S. Lawrence
Journal: Clinical Cancer Research
Clin Cancer Res (2015) 21 (13): 2898–2904.
https://doi.org/10.1158/1078-0432.CCR-13-3229
Published: 30 June 2015
View articletitled, Molecular Pathways: Overcoming Radiation Resistance by Targeting DNA Damage Response Pathways
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Journal Articles

Combined Inhibition of Wee1 and PARP1/2 for Radiosensitization in Pancreatic Cancer

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David Karnak, Carl G. Engelke, Leslie A. Parsels, Tasneem Kausar, Dongping Wei, Jordan R. Robertson, Katherine B. Marsh, Mary A. Davis, Lili Zhao, Jonathan Maybaum, Theodore S. Lawrence, Meredith A. Morgan
Journal: Clinical Cancer Research
Clin Cancer Res (2014) 20 (19): 5085–5096.
https://doi.org/10.1158/1078-0432.CCR-14-1038
Published: 30 September 2014
View articletitled, Combined Inhibition of Wee1 and PARP1/2 for Radiosensitization in Pancreatic Cancer
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Includes: Supplementary data
Journal Articles

HAb18G/CD147 Promotes pSTAT3-Mediated Pancreatic Cancer Development via CD44s

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Ling Li, Wenhua Tang, Xiaoqing Wu, David Karnak, Xiaojie Meng, Rachel Thompson, Xinbao Hao, Yongmin Li, Xiaotan T. Qiao, Jiayuh Lin, James Fuchs, Diane M. Simeone, Zhi-Nan Chen, Theodore S. Lawrence, Liang Xu
Journal: Clinical Cancer Research
Clin Cancer Res (2013) 19 (24): 6703–6715.
https://doi.org/10.1158/1078-0432.CCR-13-0621
Published: 16 December 2013
View articletitled, HAb18G/CD147 Promotes pSTAT3-Mediated Pancreatic Cancer Development via CD44s
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Includes: Supplementary data
Journal Articles

AACR Cancer Progress Report 2013

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Charles L. Sawyers, Cory Abate-Shen, Kenneth C. Anderson, Anna Barker, Jose Baselga, Nathan A. Berger, Margaret Foti, Ahmedin Jemal, Theodore S. Lawrence, Christopher I. Li, Elaine R. Mardis, Peter J. Neumann, Drew M. Pardoll, George C. Prendergast, John C. Reed, George J. Weiner
Journal: Clinical Cancer Research
Clin Cancer Res (2013) 19 (20_Supplement): S1–S98.
https://doi.org/10.1158/1078-0432.CCR-13-2107
Published: 15 October 2013
View articletitled, AACR Cancer Progress Report 2013
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Includes: Supplementary data
Journal Articles

Inhibition of Protein Phosphatase 2A Radiosensitizes Pancreatic Cancers by Modulating CDC25C/CDK1 and Homologous Recombination Repair

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Dongping Wei, Leslie A. Parsels, David Karnak, Mary A. Davis, Joshua D. Parsels, Amanda C. Marsh, Lili Zhao, Jonathan Maybaum, Theodore S. Lawrence, Yi Sun, Meredith A. Morgan
Journal: Clinical Cancer Research
Clin Cancer Res (2013) 19 (16): 4422–4432.
https://doi.org/10.1158/1078-0432.CCR-13-0788
Published: 13 August 2013
View articletitled, Inhibition of Protein Phosphatase 2A Radiosensitizes Pancreatic Cancers by Modulating CDC25C/CDK1 and Homologous Recombination Repair
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Includes: Supplementary data
Journal Articles

Sensitization of Pancreatic Cancer to Chemoradiation by the Chk1 Inhibitor MK8776

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Carl G. Engelke, Leslie A. Parsels, Yushen Qian, Qiang Zhang, David Karnak, Jordan R. Robertson, Daria M. Tanska, Dongping Wei, Mary A. Davis, Joshua D. Parsels, Lili Zhao, Joel K. Greenson, Theodore S. Lawrence, Jonathan Maybaum, Meredith A. Morgan
Journal: Clinical Cancer Research
Clin Cancer Res (2013) 19 (16): 4412–4421.
https://doi.org/10.1158/1078-0432.CCR-12-3748
Published: 13 August 2013
View articletitled, Sensitization of Pancreatic Cancer to Chemoradiation by the Chk1 Inhibitor MK8776
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Includes: Supplementary data
Journal Articles

Prospective Analysis of Parametric Response Map–Derived MRI Biomarkers: Identification of Early and Distinct Glioma Response Patterns Not Predicted by Standard Radiographic Assessment

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Craig J. Galbán, Thomas L. Chenevert, Charles R. Meyer, Christina Tsien, Theodore S. Lawrence, Daniel A. Hamstra, Larry Junck, Pia C. Sundgren, Timothy D. Johnson, Stefanie Galbán, Judith S. Sebolt-Leopold, Alnawaz Rehemtulla, Brian D. Ross
Journal: Clinical Cancer Research
Clin Cancer Res (2011) 17 (14): 4751–4760.
https://doi.org/10.1158/1078-0432.CCR-10-2098
Published: 17 July 2011
View articletitled, Prospective Analysis of Parametric Response Map–Derived MRI Biomarkers: Identification of Early and Distinct Glioma Response Patterns Not Predicted by Standard Radiographic Assessment
Open the PDF for Prospective Analysis of Parametric Response Map–Derived MRI Biomarkers: Identification of Early and Distinct Glioma Response Patterns Not Predicted by Standard Radiographic Assessment in another window
Journal Articles

Modeling the Tumor Growth Profiles in Xenograft Experiments—Response

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Lili Zhao, Meredith A. Morgan, Leslie A. Parsels, Jonathan Maybaum, Theodore S. Lawrence, Daniel Normolle
Journal: Clinical Cancer Research
Clin Cancer Res (2011) 17 (13): 4613.
https://doi.org/10.1158/1078-0432.CCR-11-0888
Published: 05 July 2011
View articletitled, Modeling the Tumor Growth Profiles in Xenograft Experiments—Response
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Journal Articles

Assessment of Chk1 Phosphorylation as a Pharmacodynamic Biomarker of Chk1 Inhibition

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Leslie A. Parsels, Yushen Qian, Daria M. Tanska, Marisa Gross, Lili Zhao, Maria C. Hassan, Sankari Arumugarajah, Joshua D. Parsels, Linda Hylander-Gans, Diane M. Simeone, Deborah Morosini, Jeffrey L. Brown, Sonya D. Zabludoff, Jonathan Maybaum, Theodore S. Lawrence, Meredith A. Morgan
Journal: Clinical Cancer Research
Clin Cancer Res (2011) 17 (11): 3706–3715.
https://doi.org/10.1158/1078-0432.CCR-10-3082
Published: 01 June 2011
View articletitled, Assessment of Chk1 Phosphorylation as a Pharmacodynamic Biomarker of Chk1 Inhibition
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Includes: Supplementary data
Journal Articles

Bayesian Hierarchical Changepoint Methods in Modeling the Tumor Growth Profiles in Xenograft Experiments

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Lili Zhao, Meredith A. Morgan, Leslie A. Parsels, Jonathan Maybaum, Theodore S. Lawrence, Daniel Normolle
Journal: Clinical Cancer Research
Clin Cancer Res (2011) 17 (5): 1057–1064.
https://doi.org/10.1158/1078-0432.CCR-10-1935
Published: 01 March 2011
View articletitled, Bayesian Hierarchical Changepoint Methods in Modeling the Tumor Growth Profiles in Xenograft Experiments
Open the PDF for Bayesian Hierarchical Changepoint Methods in Modeling the Tumor Growth Profiles in Xenograft Experiments in another window
Includes: Supplementary data