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Journal Articles

Correction: BRD9 Degradation Disrupts Ribosome Biogenesis in Multiple Myeloma

Open Access
Keiji Kurata, Mehmet K. Samur, Priscilla Liow, Kenneth Wen, Leona Yamamoto, Jiye Liu, Eugenio Morelli, Annamaria Gulla, Yu-Tzu Tai, Jun Qi, Teru Hideshima, Kenneth C. Anderson
Journal: Clinical Cancer Research
Clin Cancer Res (2024) 30 (17): 3956.
https://doi.org/10.1158/1078-0432.CCR-24-2112
Published: 03 September 2024
View articletitled, Correction: BRD9 Degradation Disrupts Ribosome Biogenesis in Multiple Myeloma
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Journal Articles

Editor's Note: A 13 mer LNA-i-miR-221 Inhibitor Restores Drug Sensitivity in Melphalan-Refractory Multiple Myeloma Cells

Free
Annamaria Gullà, Maria Teresa Di Martino, Maria Eugenia Gallo Cantafio, Eugenio Morelli, Nicola Amodio, Cirino Botta, Maria Rita Pitari, Santo Giovanni Lio, Domenico Britti, Maria Angelica Stamato, Teru Hideshima, Nikhil C. Munshi, Kenneth C. Anderson, Pierosandro Tagliaferri, Pierfrancesco Tassone
Journal: Clinical Cancer Research
Clin Cancer Res (2024) 30 (10): 2288.
https://doi.org/10.1158/1078-0432.CCR-24-1089
Published: 15 May 2024
View articletitled, Editor's Note: A 13 mer LNA-i-miR-221 Inhibitor Restores Drug Sensitivity in Melphalan-Refractory Multiple Myeloma Cells
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Journal Articles

Editor's Note: Targeting Akt and Heat Shock Protein 90 Produces Synergistic Multiple Myeloma Cell Cytotoxicity in the Bone Marrow Microenvironment

Free
Alissa Huston, Xavier Leleu, Xiaoying Jia, Anne-Sophie Moreau, Hai T. Ngo, Judith Runnels, Judy Anderson, Yazan Alsayed, Aldo Roccaro, Sonia Vallet, Evdoxia Hatjiharissi, Yu-Tsu Tai, Peter Sportelli, Nikhil Munshi, Paul Richardson, Teru Hideshima, David G. Roodman, Kenneth C. Anderson, Irene M. Ghobrial
Journal: Clinical Cancer Research
Clin Cancer Res (2024) 30 (4): 922.
https://doi.org/10.1158/1078-0432.CCR-24-0181
Published: 16 February 2024
View articletitled, Editor's Note: Targeting Akt and Heat Shock Protein 90 Produces Synergistic Multiple Myeloma Cell Cytotoxicity in the Bone Marrow Microenvironment
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Journal Articles

BRD9 Degradation Disrupts Ribosome Biogenesis in Multiple Myeloma

Open Access
Keiji Kurata, Mehmet K. Samur, Priscilla Liow, Kenneth Wen, Leona Yamamoto, Jiye Liu, Eugenio Morelli, Annamaria Gulla, Yu-Tzu Tai, Jun Qi, Teru Hideshima, Kenneth C. Anderson
Journal: Clinical Cancer Research
Clin Cancer Res (2023) 29 (9): 1807–1821.
https://doi.org/10.1158/1078-0432.CCR-22-3668
Published: 01 May 2023
View articletitled, BRD9 Degradation Disrupts Ribosome Biogenesis in Multiple Myeloma
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Includes: Supplementary data
Journal Articles

Correction: Dual Inhibition of Canonical and Noncanonical NF-κB Pathways Demonstrates Significant Antitumor Activities in Multiple Myeloma

Free
Claire Fabre, Naoya Mimura, Kathryn Bobb, Sun-Young Kong, Güllü Gorgun, Diana Cirstea, Yiguo Hu, Jiro Minami, Hiroto Ohguchi, Jie Zhang, Jeffrey Meshulam, Ruben D. Carrasco, Yu-Tzu Tai, Paul G. Richardson, Teru Hideshima, Kenneth C. Anderson
Journal: Clinical Cancer Research
Clin Cancer Res (2019) 25 (9): 2938.
https://doi.org/10.1158/1078-0432.CCR-19-0959
Published: 01 May 2019
View articletitled, Correction: Dual Inhibition of Canonical and Noncanonical NF-κB Pathways Demonstrates Significant Antitumor Activities in Multiple Myeloma
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Journal Articles

Abstract PR13: p53-related protein kinase is a novel prognostic marker and therapeutic target in multiple myeloma

Free
Francesca Cottini, Teru Hideshima, Yoshihisa Nozawa, Hiroto Ohguchi, Teruhiro Utsugi, Kenneth C Anderson
Journal: Clinical Cancer Research
Clin Cancer Res (2017) 23 (24_Supplement): PR13.
https://doi.org/10.1158/1557-3265.HEMMAL17-PR13
Published: 14 December 2017
View articletitled, Abstract PR13: p53-related protein kinase is a novel prognostic marker and therapeutic target in multiple myeloma
Journal Articles

Ribonucleotide Reductase Catalytic Subunit M1 (RRM1) as a Novel Therapeutic Target in Multiple Myeloma

Free
Morihiko Sagawa, Hiroto Ohguchi, Takeshi Harada, Mehmet K. Samur, Yu-Tzu Tai, Nikhil C. Munshi, Masahiro Kizaki, Teru Hideshima, Kenneth C. Anderson
Journal: Clinical Cancer Research
Clin Cancer Res (2017) 23 (17): 5225–5237.
https://doi.org/10.1158/1078-0432.CCR-17-0263
Published: 31 August 2017
View articletitled, Ribonucleotide Reductase Catalytic Subunit M1 (RRM1) as a Novel Therapeutic Target in Multiple Myeloma
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Includes: Supplementary data
Journal Articles

Dual NAMPT and BTK Targeting Leads to Synergistic Killing of Waldenström Macroglobulinemia Cells Regardless of MYD88 and CXCR4 Somatic Mutation Status

Free
Michele Cea, Antonia Cagnetta, Chirag Acharya, Prakrati Acharya, Yu-Tzu Tai, Cao Yang, Davide Lovera, Debora Soncini, Maurizio Miglino, Giulio Fraternali-Orcioni, Luca Mastracci, Alessio Nencioni, Fabrizio Montecucco, Fiammetta Monacelli, Alberto Ballestrero, Teru Hideshima, Dharminder Chauhan, Marco Gobbi, Roberto M. Lemoli, Nikhil Munshi, Steven P. Treon, Kenneth C. Anderson
Journal: Clinical Cancer Research
Clin Cancer Res (2016) 22 (24): 6099–6109.
https://doi.org/10.1158/1078-0432.CCR-16-0630
Published: 15 December 2016
View articletitled, Dual NAMPT and BTK Targeting Leads to Synergistic Killing of Waldenström Macroglobulinemia Cells Regardless of MYD88 and CXCR4 Somatic Mutation Status
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Includes: Supplementary data
Journal Articles

A 13 mer LNA-i-miR-221 Inhibitor Restores Drug Sensitivity in Melphalan-Refractory Multiple Myeloma Cells

Free
Annamaria Gullà, Maria Teresa Di Martino, Maria Eugenia Gallo Cantafio, Eugenio Morelli, Nicola Amodio, Cirino Botta, Maria Rita Pitari, Santo Giovanni Lio, Domenico Britti, Maria Angelica Stamato, Teru Hideshima, Nikhil C. Munshi, Kenneth C. Anderson, Pierosandro Tagliaferri, Pierfrancesco Tassone
Journal: Clinical Cancer Research
Series: Author Choice
Clin Cancer Res (2016) 22 (5): 1222–1233.
https://doi.org/10.1158/1078-0432.CCR-15-0489
Published: 29 February 2016
View articletitled, A 13 mer LNA-i-miR-221 Inhibitor Restores Drug Sensitivity in Melphalan-Refractory Multiple Myeloma Cells
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Includes: Supplementary data
Journal Articles

Lenalidomide Enhances Immune Checkpoint Blockade-Induced Immune Response in Multiple Myeloma

Free
Güllü Görgün, Mehmet K. Samur, Kristen B. Cowens, Steven Paula, Giada Bianchi, Julie E. Anderson, Randie E. White, Ahaana Singh, Hiroto Ohguchi, Rikio Suzuki, Shohei Kikuchi, Takeshi Harada, Teru Hideshima, Yu-Tzu Tai, Jacob P. Laubach, Noopur Raje, Florence Magrangeas, Stephane Minvielle, Herve Avet-Loiseau, Nikhil C. Munshi, David M. Dorfman, Paul G. Richardson, Kenneth C. Anderson
Journal: Clinical Cancer Research
Clin Cancer Res (2015) 21 (20): 4607–4618.
https://doi.org/10.1158/1078-0432.CCR-15-0200
Published: 14 October 2015
View articletitled, Lenalidomide Enhances Immune Checkpoint Blockade-Induced Immune Response in Multiple Myeloma
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Includes: Supplementary data
Journal Articles

Abstract PR04: Exploiting oncogene-induced DNA replicative stress as synthetic lethal approach to target myeloma.

Free
Francesca Cottini, Teru Hideshima, Paul Richardson, Kenneth Anderson, Giovanni Tonon
Journal: Clinical Cancer Research
Clin Cancer Res (2015) 21 (17_Supplement): PR04.
https://doi.org/10.1158/1557-3265.HEMMAL14-PR04
Published: 19 August 2015
View articletitled, Abstract PR04: Exploiting oncogene-induced DNA replicative stress as synthetic lethal approach to target myeloma.
Journal Articles

Abstract B09: Exploiting oncogene-induced DNA replicative stress as synthetic lethal approach to target myeloma.

Free
Francesca Cottini, Teru Hideshima, Paul Richardson, Kenneth Anderson, Giovanni Tonon
Journal: Clinical Cancer Research
Clin Cancer Res (2015) 21 (17_Supplement): B09.
https://doi.org/10.1158/1557-3265.HEMMAL14-B09
Published: 19 August 2015
View articletitled, Abstract B09: Exploiting oncogene-induced DNA replicative stress as synthetic lethal approach to target myeloma.
Journal Articles

Dual Inhibition of Canonical and Noncanonical NF-κB Pathways Demonstrates Significant Antitumor Activities in Multiple Myeloma

Free
Claire Fabre, Naoya Mimura, Kathryn Bobb, Sun-Young Kong, Güllü Gorgun, Diana Cirstea, Yiguo Hu, Jiro Minami, Hiroto Ohguchi, Jie Zhang, Jeffrey Meshulam, Ruben D. Carrasco, Yu-Tzu Tai, Paul G. Richardson, Teru Hideshima, Kenneth C. Anderson
Journal: Clinical Cancer Research
Clin Cancer Res (2012) 18 (17): 4669–4681.
https://doi.org/10.1158/1078-0432.CCR-12-0779
Published: 30 August 2012
View articletitled, Dual Inhibition of Canonical and Noncanonical NF-κB Pathways Demonstrates Significant Antitumor Activities in Multiple Myeloma
Open the PDF for Dual Inhibition of Canonical and Noncanonical NF-κB Pathways Demonstrates Significant Antitumor Activities in Multiple Myeloma in another window
Includes: Supplementary data
Journal Articles

Significant Biological Role of Sp1 Transactivation in Multiple Myeloma

Free
Mariateresa Fulciniti, Samir Amin, Puru Nanjappa, Scott Rodig, Rao Prabhala, Cheng Li, Stephane Minvielle, Yu-tzu Tai, Pierfrancesco Tassone, Herve Avet-Loiseau, Teru Hideshima, Kenneth C. Anderson, Nikhil C. Munshi
Journal: Clinical Cancer Research
Clin Cancer Res (2011) 17 (20): 6500–6509.
https://doi.org/10.1158/1078-0432.CCR-11-1036
Published: 14 October 2011
View articletitled, Significant Biological Role of Sp1 Transactivation in Multiple Myeloma
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Includes: Supplementary data
Journal Articles

Antimyeloma Activity of a Multitargeted Kinase Inhibitor, AT9283, via Potent Aurora Kinase and STAT3 Inhibition Either Alone or in Combination with Lenalidomide

Free
Loredana Santo, Teru Hideshima, Diana Cirstea, Madhavi Bandi, Erik A. Nelson, Gullu Gorgun, Scott Rodig, Sonia Vallet, Samantha Pozzi, Kishan Patel, Christine Unitt, Matt Squires, Yiguo Hu, Dharminder Chauhan, Anuj Mahindra, Nikhil C. Munshi, Kenneth C. Anderson, Noopur Raje
Journal: Clinical Cancer Research
Clin Cancer Res (2011) 17 (10): 3259–3271.
https://doi.org/10.1158/1078-0432.CCR-10-3012
Published: 15 May 2011
View articletitled, Antimyeloma Activity of a Multitargeted Kinase Inhibitor, AT9283, via Potent Aurora Kinase and STAT3 Inhibition Either Alone or in Combination with Lenalidomide
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Journal Articles

A High-Affinity Fully Human Anti–IL-6 mAb, 1339, for the Treatment of Multiple Myeloma

Free
Mariateresa Fulciniti, Teru Hideshima, Claudine Vermot-Desroches, Samantha Pozzi, Puru Nanjappa, Zhenxin Shen, Nipun Patel, Ernest S. Smith, Wei Wang, Rao Prabhala, Yu-tzu Tai, Pierfrancesco Tassone, Kenneth C. Anderson, Nikhil C. Munshi
Journal: Clinical Cancer Research
Clin Cancer Res (2009) 15 (23): 7144–7152.
https://doi.org/10.1158/1078-0432.CCR-09-1483
Published: 30 November 2009
View articletitled, A High-Affinity Fully Human Anti–IL-6 mAb, 1339, for the Treatment of Multiple Myeloma
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Journal Articles

Interactions of the Hdm2/p53 and Proteasome Pathways May Enhance the Antitumor Activity of Bortezomib

Free
Melissa G. Ooi, Patrick J. Hayden, Vassiliki Kotoula, Douglas W. McMillin, Elpida Charalambous, Emily Daskalaki, Noopur S. Raje, Nikhil C. Munshi, Dharminder Chauhan, Teru Hideshima, Leutz Buon, Martin Clynes, Peter O'Gorman, Paul G. Richardson, Constantine S. Mitsiades, Kenneth C. Anderson, Nicholas Mitsiades
Journal: Clinical Cancer Research
Clin Cancer Res (2009) 15 (23): 7153–7160.
https://doi.org/10.1158/1078-0432.CCR-09-1071
Published: 30 November 2009
View articletitled, Interactions of the Hdm2/p53 and Proteasome Pathways May Enhance the Antitumor Activity of Bortezomib
Open the PDF for Interactions of the Hdm2/p53 and Proteasome Pathways May Enhance the Antitumor Activity of Bortezomib in another window
Includes: Supplementary data
Journal Articles

High-Dose Zoledronic Acid Impacts Bone Remodeling with Effects on Osteoblastic Lineage and Bone Mechanical Properties

Free
Samantha Pozzi, Sonia Vallet, Siddhartha Mukherjee, Diana Cirstea, Nileshwari Vaghela, Loredana Santo, Eyal Rosen, Hiroshi Ikeda, Yutaka Okawa, Tanyel Kiziltepe, Jesse Schoonmaker, Wanling Xie, Teru Hideshima, Edie Weller, Mary L. Bouxsein, Nikhil C. Munshi, Kenneth C. Anderson, Noopur Raje
Journal: Clinical Cancer Research
Clin Cancer Res (2009) 15 (18): 5829–5839.
https://doi.org/10.1158/1078-0432.CCR-09-0426
Published: 14 September 2009
View articletitled, High-Dose Zoledronic Acid Impacts Bone Remodeling with Effects on Osteoblastic Lineage and Bone Mechanical Properties
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Journal Articles

The Monoclonal Antibody nBT062 Conjugated to Cytotoxic Maytansinoids Has Selective Cytotoxicity Against CD138-Positive Multiple Myeloma Cells In vitro and In vivo

Free
Hiroshi Ikeda, Teru Hideshima, Mariateresa Fulciniti, Robert J. Lutz, Hiroshi Yasui, Yutaka Okawa, Tanyel Kiziltepe, Sonia Vallet, Samantha Pozzi, Loredana Santo, Giulia Perrone, Yu-Tzu Tai, Diana Cirstea, Noopur S. Raje, Christoph Uherek, Benjamin Dälken, Silke Aigner, Frank Osterroth, Nikhil Munshi, Paul Richardson, Kenneth C. Anderson
Journal: Clinical Cancer Research
Clin Cancer Res (2009) 15 (12): 4028–4037.
https://doi.org/10.1158/1078-0432.CCR-08-2867
Published: 15 June 2009
View articletitled, The Monoclonal Antibody nBT062 Conjugated to Cytotoxic Maytansinoids Has Selective Cytotoxicity Against CD138-Positive Multiple Myeloma Cells In vitro and In vivo
Open the PDF for The Monoclonal Antibody nBT062 Conjugated to Cytotoxic Maytansinoids Has Selective Cytotoxicity Against CD138-Positive Multiple Myeloma Cells In vitro and In vivo in another window
Includes: Supplementary data
Journal Articles

Clinical, Radiographic, and Biochemical Characterization of Multiple Myeloma Patients with Osteonecrosis of the Jaw

Free
Noopur Raje, Sook-Bin Woo, Karen Hande, Jeffrey T. Yap, Paul G. Richardson, Sonia Vallet, Nathaniel Treister, Teru Hideshima, Niall Sheehy, Shweta Chhetri, Brendan Connell, Wanling Xie, Yu-Tzu Tai, Agnieszka Szot-Barnes, Mei Tian, Robert L. Schlossman, Edie Weller, Nikhil C. Munshi, Annick D. Van Den Abbeele, Kenneth C. Anderson
Journal: Clinical Cancer Research
Clin Cancer Res (2008) 14 (8): 2387–2395.
https://doi.org/10.1158/1078-0432.CCR-07-1430
Published: 15 April 2008
View articletitled, Clinical, Radiographic, and Biochemical Characterization of Multiple Myeloma Patients with Osteonecrosis of the Jaw
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