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Suzanne Kyle
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Journal Articles

Development of a Functional Assay for Homologous Recombination Status in Primary Cultures of Epithelial Ovarian Tumor and Correlation with Sensitivity to Poly(ADP-Ribose) Polymerase Inhibitors

Asima Mukhopadhyay, Ahmed Elattar, Aiste Cerbinskaite, Sarah J. Wilkinson, Yvette Drew, Suzanne Kyle, Gerrit Los, Zdenek Hostomsky, Richard J. Edmondson, Nicola J. Curtin
Journal: Clinical Cancer Research
Clin Cancer Res (2010) 16 (8): 2344–2351.
https://doi.org/10.1158/1078-0432.CCR-09-2758
Published: 14 April 2010
View article titled, Development of a Functional Assay for Homologous Recombination Status in Primary Cultures of Epithelial Ovarian Tumor and Correlation with Sensitivity to Poly(ADP-Ribose) Polymerase Inhibitors
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Includes: Supplementary data
Journal Articles

Vasoactivity of AG014699, a Clinically Active Small Molecule Inhibitor of Poly(ADP-ribose) Polymerase: a Contributory Factor to Chemopotentiation In vivo?

Majid Ali, Brian A. Telfer, Cian McCrudden, Martin O'Rourke, Huw D. Thomas, Marzieh Kamjoo, Suzanne Kyle, Tracy Robson, Chris Shaw, David G. Hirst, Nicola J. Curtin, Kaye J. Williams
Journal: Clinical Cancer Research
Clin Cancer Res (2009) 15 (19): 6106–6112.
https://doi.org/10.1158/1078-0432.CCR-09-0398
Published: 30 September 2009
View article titled, Vasoactivity of AG014699, a Clinically Active Small Molecule Inhibitor of Poly(ADP-ribose) Polymerase: a Contributory Factor to Chemopotentiation <em>In vivo</em>?
Open the PDF for Vasoactivity of AG014699, a Clinically Active Small Molecule Inhibitor of Poly(ADP-ribose) Polymerase: a Contributory Factor to Chemopotentiation <em>In vivo</em>? in another window
Includes: Supplementary data
Journal Articles

Novel Poly(ADP-ribose) Polymerase-1 Inhibitor, AG14361, Restores Sensitivity to Temozolomide in Mismatch Repair-Deficient Cells

Nicola J. Curtin, Lan-Zhen Wang, Anthie Yiakouvaki, Suzanne Kyle, Christine A. Arris, Stacie Canan-Koch, Stephen E. Webber, Barbara W. Durkacz, Hilary A. Calvert, Zdenek Hostomsky, David R. Newell
Journal: Clinical Cancer Research
Clin Cancer Res (2004) 10 (3): 881–889.
https://doi.org/10.1158/1078-0432.CCR-1144-3
Published: 10 February 2004
View article titled, Novel Poly(ADP-ribose) Polymerase-1 Inhibitor, AG14361, Restores Sensitivity to Temozolomide in Mismatch Repair-Deficient Cells
Open the PDF for Novel Poly(ADP-ribose) Polymerase-1 Inhibitor, AG14361, Restores Sensitivity to Temozolomide in Mismatch Repair-Deficient Cells in another window
Journal Articles

Identification of Potent Nontoxic Poly(ADP-Ribose) Polymerase-1 Inhibitors: Chemopotentiation and Pharmacological Studies

Christopher R. Calabrese, Michael A. Batey, Huw D. Thomas, Barbara W. Durkacz, Lan-Zhen Wang, Suzanne Kyle, Donald Skalitzky, Janke Li, Catherine Zhang, Theodore Boritzki, Karen Maegley, Alan H. Calvert, Zdenek Hostomsky, David R. Newell, Nicola J. Curtin
Journal: Clinical Cancer Research
Clin Cancer Res (2003) 9 (7): 2711–2718.
Published: 01 July 2003
View article titled, Identification of Potent Nontoxic Poly(ADP-Ribose) Polymerase-1 Inhibitors: <subtitle>Chemopotentiation and Pharmacological Studies</subtitle>
Open the PDF for Identification of Potent Nontoxic Poly(ADP-Ribose) Polymerase-1 Inhibitors: <subtitle>Chemopotentiation and Pharmacological Studies</subtitle> in another window
Journal Articles

Potentiation of Temozolomide and Topotecan Growth Inhibition and Cytotoxicity by Novel Poly(adenosine Diphosphoribose) Polymerase Inhibitors in a Panel of Human Tumor Cell Lines

Carol A. Delaney, Lan-Z Wang, Suzanne Kyle, Alex W. White, A. Hilary Calvert, Nicola J. Curtin, Barbara W. Durkacz, Zdenek Hostomsky, David R. Newell
Journal: Clinical Cancer Research
Clin Cancer Res (2000) 6 (7): 2860–2867.
Published: 01 July 2000
View article titled, Potentiation of Temozolomide and Topotecan Growth Inhibition and Cytotoxicity by Novel Poly(adenosine Diphosphoribose) Polymerase Inhibitors in a Panel of Human Tumor Cell Lines
Open the PDF for Potentiation of Temozolomide and Topotecan Growth Inhibition and Cytotoxicity by Novel Poly(adenosine Diphosphoribose) Polymerase Inhibitors in a Panel of Human Tumor Cell Lines in another window