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Suzanne Dowson
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Journal Articles

Structural Variants at the BRCA1/2 Loci are a Common Source of Homologous Repair Deficiency in High-grade Serous Ovarian Carcinoma

Ailith Ewing, Alison Meynert, Michael Churchman, Graeme R. Grimes, Robert L. Hollis, C. Simon Herrington, Tzyvia Rye, Clare Bartos, Ian Croy, Michelle Ferguson, Mairi Lennie, Trevor McGoldrick, Neil McPhail, Nadeem Siddiqui, Suzanne Dowson, Rosalind Glasspool, Melanie Mackean, Fiona Nussey, Brian McDade, Darren Ennis, Lynn McMahon, Athena Matakidou, Brian Dougherty, Ruth March, J. Carl Barrett, Iain A. McNeish, for the Scottish Genomes Partnership, Andrew V. Biankin, Patricia Roxburgh, Charlie Gourley, Colin A. Semple
Journal: Clinical Cancer Research
Series: Author Choice
Clin Cancer Res (2021) 27 (11): 3201–3214.
https://doi.org/10.1158/1078-0432.CCR-20-4068
Published: 01 June 2021
View article titled, Structural Variants at the <em>BRCA1/2</em> Loci are a Common Source of Homologous Repair Deficiency in High-grade Serous Ovarian Carcinoma
Open the PDF for Structural Variants at the <em>BRCA1/2</em> Loci are a Common Source of Homologous Repair Deficiency in High-grade Serous Ovarian Carcinoma in another window
Includes: Supplementary data
Journal Articles

Abstract AP09: COPY-NUMBER SIGNATURES AND MUTATIONAL PROCESSES IN HIGH GRADE SEROUS OVARIAN CARCINOMA

Geoff Macintyre, Teodora E. Goranova, Dilrini De Silva, Darren Ennis, Anna M. Piskorz, Matthew Eldridge, Daoud Sie, Liz-Anne Lewsley, Aishah Hanif, Cheryl Wilson, Suzanne Dowson, Rosalind M. Glasspool, Michelle Lockley, Elly Brockbank, Ana Montes, Axel Walther, Sudha Sundar, Richard Edmondson, Geoff D. Hall, Andrew Clamp, Charlie Gourley, Marcia Hall, Christina Fotopoulou, Hani Gabra, James Paul, Anna Supernat, David Millan, Aoisha Hoyle, Gareth Bryson, Craig Nourse, Laura Mincarelli, Luis Navarro Sanchez, Bauke Ylstra, Mercedes Jimenez-Linan, Luiza Moore, Oliver Hofmann, Florian Markowetz, Iain A. McNeish, James D. Brenton
Journal: Clinical Cancer Research
Clin Cancer Res (2019) 25 (22_Supplement): AP09.
https://doi.org/10.1158/1557-3265.OVCASYMP18-AP09
Published: 15 November 2019
View article titled, Abstract AP09: COPY-NUMBER SIGNATURES AND MUTATIONAL PROCESSES IN HIGH GRADE SEROUS OVARIAN CARCINOMA
Journal Articles

Abstract A37: Epigenetic modification of ovarian cancer immunogenicity

Pavlina Spiliopoulou, Josephine Walton, Suzanne Dowson, Alex Binks, Oliver Maddocks, Peter Adams, Iain McNeish
Journal: Clinical Cancer Research
Clin Cancer Res (2018) 24 (15_Supplement): A37.
https://doi.org/10.1158/1557-3265.OVCA17-A37
Published: 01 August 2018
View article titled, Abstract A37: Epigenetic modification of ovarian cancer immunogenicity
Journal Articles

Abstract PR14: CRISPR/Cas9-mediated Trp53, Brca1, Brca2, Pten, and Nf1 knockout to generate improved murine models of ovarian high-grade serous carcinoma

Josephine Walton, Malcolm Farquharson, Susan Mason, Julianna Blagih, Darren Ennis, Elaine Leung, Suzanne Dowson, Dimitris Athineos, Damiano Rami, David Stevenson, Seth Coffelt, Karen Blyth, Douglas Strathdee, Frances Balkwill, Karen Vousden, Michelle Lockley, Iain McNeish
Journal: Clinical Cancer Research
Clin Cancer Res (2018) 24 (15_Supplement): PR14.
https://doi.org/10.1158/1557-3265.OVCA17-PR14
Published: 01 August 2018
View article titled, Abstract PR14: CRISPR/Cas9-mediated <em>Trp53, Brca1, Brca2, Pten,</em> and <em>Nf1</em> knockout to generate improved murine models of ovarian high-grade serous carcinoma
Journal Articles

The Driver Mutational Landscape of Ovarian Squamous Cell Carcinomas Arising in Mature Cystic Teratoma

Susanna L. Cooke, Darren Ennis, Lisa Evers, Suzanne Dowson, Mei Yen Chan, James Paul, Lynn Hirschowitz, Rosalind M. Glasspool, Naveena Singh, Sarah Bell, Elizabeth Day, Agata Kochman, Nafisa Wilkinson, Philip Beer, Sancha Martin, David Millan, Andrew V. Biankin, Iain A. McNeish
Journal: Clinical Cancer Research
Clin Cancer Res (2017) 23 (24): 7633–7640.
https://doi.org/10.1158/1078-0432.CCR-17-1789
Published: 14 December 2017
View article titled, The Driver Mutational Landscape of Ovarian Squamous Cell Carcinomas Arising in Mature Cystic Teratoma
Open the PDF for The Driver Mutational Landscape of Ovarian Squamous Cell Carcinomas Arising in Mature Cystic Teratoma in another window
Includes: Supplementary data
Journal Articles

Abstract AP24: CRISPR/CAS9–MEDIATED TRP53, BRCA1, BRCA2 AND PTEN KNOCKOUT TO GENERATE IMPROVED MURINE MODELS OF OVARIAN HIGH GRADE SEROUS CARCINOMA

Josephine Walton, Julianna Blagih, Malcolm Farquharson, Darren Ennis, Elaine Leung, Suzanne Dowson, Laura A. Tookman, Clare Orange, Dimitris Athineos, Susan Mason, David Stevenson, Karen Blyth, Douglas Strathdee, Frances R. Balkwill, Karen Vousden, Michelle Lockley, Iain A. McNeish
Journal: Clinical Cancer Research
Clin Cancer Res (2017) 23 (11_Supplement): AP24.
https://doi.org/10.1158/1557-3265.OVCASYMP16-AP24
Published: 31 May 2017
View article titled, Abstract AP24: CRISPR/CAS9–MEDIATED <em>TRP53</em>, <em>BRCA1</em>, <em>BRCA2</em> AND <em>PTEN</em> KNOCKOUT TO GENERATE IMPROVED MURINE MODELS OF OVARIAN HIGH GRADE SEROUS CARCINOMA
Journal Articles

Abstract B53: CRISPR/Cas9 mediated p53 and BRCA2 knockout to generate improved murine models of high grade serous ovarian cancer.

Josephine Walton, Suzanne Dowson, Darren Ennis, Elaine Leung, Malcolm Farquharson, David Stevenson, Karen Blyth, Douglas Strathdee, Frances R. Balkwill, Michelle Lockley, Iain A. McNeish
Journal: Clinical Cancer Research
Clin Cancer Res (2016) 22 (2_Supplement): B53.
https://doi.org/10.1158/1557-3265.OVCA15-B53
Published: 15 January 2016
View article titled, Abstract B53: CRISPR/Cas9 mediated p53 and BRCA2 knockout to generate improved murine models of high grade serous ovarian cancer.