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Sushil Kumar
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Journal Articles

A B7-H4–Targeting Antibody–Drug Conjugate Shows Antitumor Activity in PARPi and Platinum-Resistant Cancers with B7-H4 Expression

Sarah B. Gitto, Margaret Whicker, Gareth Davies, Sushil Kumar, Krista Kinneer, Haineng Xu, Arthur Lewis, Srinivas Mamidi, Sergey Medvedev, Hyoung Kim, Judith Anderton, E. Jessica Tang, Benjamin Ferman, Steven Coats, Robert W. Wilkinson, Eric Brown, Daniel J. Powell, Jr, Fiona Simpkins
Journal: Clinical Cancer Research
Clin Cancer Res (2024) 30 (8): 1567–1581.
https://doi.org/10.1158/1078-0432.CCR-23-1079
Published: 15 April 2024
View article titled, A B7-H4–Targeting Antibody–Drug Conjugate Shows Antitumor Activity in PARPi and Platinum-Resistant Cancers with B7-H4 Expression
Open the PDF for A B7-H4–Targeting Antibody–Drug Conjugate Shows Antitumor Activity in PARPi and Platinum-Resistant Cancers with B7-H4 Expression in another window
Includes: Supplementary data
Journal Articles

Mucin Expression and Splicing Determine Novel Subtypes and Patient Mortality in Pancreatic Ductal Adenocarcinoma

Christopher M. Thompson, Andrew Cannon, Sean West, Dario Ghersi, Pranita Atri, Rakesh Bhatia, Lynette Smith, Satyayanarayana Rachagani, Christopher Wichman, Sushil Kumar, Surinder K. Batra
Journal: Clinical Cancer Research
Clin Cancer Res (2021) 27 (24): 6787–6799.
https://doi.org/10.1158/1078-0432.CCR-21-1591
Published: 15 December 2021
View article titled, Mucin Expression and Splicing Determine Novel Subtypes and Patient Mortality in Pancreatic Ductal Adenocarcinoma
Open the PDF for Mucin Expression and Splicing Determine Novel Subtypes and Patient Mortality in Pancreatic Ductal Adenocarcinoma in another window
Includes: Supplementary data
Journal Articles

Abstract PO-084: Automated detection of pancreatic ductal adenocarcinoma (PDAC) on CT scans using artificial intelligence (AI): Impact of inclusion of automated pancreas segmentation on the accuracy of 3D-convolutional neural network (CNN)

Anurima Patra, Korfiatis Panagiotis, Garima Suman, Ananya Panda, Sushil Kumar Garg, Ajit Goenka
Journal: Clinical Cancer Research
Clin Cancer Res (2021) 27 (5_Supplement): PO-084.
https://doi.org/10.1158/1557-3265.ADI21-PO-084
Published: 01 March 2021
View article titled, Abstract PO-084: Automated detection of pancreatic ductal adenocarcinoma (PDAC) on CT scans using artificial intelligence (AI): Impact of inclusion of automated pancreas segmentation on the accuracy of 3D-convolutional neural network (CNN)
Journal Articles

CXCR3 and Cognate Ligands are Associated with Immune Cell Alteration and Aggressiveness of Pancreatic Ductal Adenocarcinoma

Andrew Cannon, Christopher M. Thompson, H. Carlo Maurer, Pranita Atri, Rakesh Bhatia, Sean West, Dario Ghersi, Kenneth P. Olive, Sushil Kumar, Surinder K. Batra
Journal: Clinical Cancer Research
Clin Cancer Res (2020) 26 (22): 6051–6063.
https://doi.org/10.1158/1078-0432.CCR-20-1359
Published: 13 November 2020
View article titled, CXCR3 and Cognate Ligands are Associated with Immune Cell Alteration and Aggressiveness of Pancreatic Ductal Adenocarcinoma
Open the PDF for CXCR3 and Cognate Ligands are Associated with Immune Cell Alteration and Aggressiveness of Pancreatic Ductal Adenocarcinoma in another window
Includes: Supplementary data
Journal Articles

Clinical Response of Live-Attenuated, Listeria monocytogenes Expressing Mesothelin (CRS-207) with Chemotherapy in Patients with Malignant Pleural Mesothelioma

Raffit Hassan, Evan Alley, Hedy Kindler, Scott Antonia, Thierry Jahan, Somayeh Honarmand, Nitya Nair, Chan C. Whiting, Amanda Enstrom, Ed Lemmens, Takahiro Tsujikawa, Sushil Kumar, Gina Choe, Anish Thomas, Katherine McDougall, Aimee L. Murphy, Elizabeth Jaffee, Lisa M. Coussens, Dirk G. Brockstedt
Journal: Clinical Cancer Research
Clin Cancer Res (2019) 25 (19): 5787–5798.
https://doi.org/10.1158/1078-0432.CCR-19-0070
Published: 01 October 2019
View article titled, Clinical Response of Live-Attenuated, <em>Listeria monocytogenes</em> Expressing Mesothelin (CRS-207) with Chemotherapy in Patients with Malignant Pleural Mesothelioma
Open the PDF for Clinical Response of Live-Attenuated, <em>Listeria monocytogenes</em> Expressing Mesothelin (CRS-207) with Chemotherapy in Patients with Malignant Pleural Mesothelioma in another window
Includes: Supplementary data
Journal Articles

Ketoconazole and Posaconazole Selectively Target HK2-expressing Glioblastoma Cells

Sameer Agnihotri, Sheila Mansouri, Kelly Burrell, Mira Li, Yasin Mamatjan, Jeff Liu, Romina Nejad, Sushil Kumar, Shahrzad Jalali, Sanjay K. Singh, Alenoush Vartanian, Eric Xueyu Chen, Shirin Karimi, Olivia Singh, Severa Bunda, Alireza Mansouri, Kenneth D. Aldape, Gelareh Zadeh
Journal: Clinical Cancer Research
Series: Author Choice
Clin Cancer Res (2019) 25 (2): 844–855.
https://doi.org/10.1158/1078-0432.CCR-18-1854
Published: 15 January 2019
View article titled, Ketoconazole and Posaconazole Selectively Target HK2-expressing Glioblastoma Cells
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Includes: Supplementary data
Journal Articles

Combined Antitumor Therapy with Metronomic Topotecan and Hypoxia-Activated Prodrug, Evofosfamide, in Neuroblastoma and Rhabdomyosarcoma Preclinical Models

Libo Zhang, Paula Marrano, Bing Wu, Sushil Kumar, Paul Thorner, Sylvain Baruchel
Journal: Clinical Cancer Research
Clin Cancer Res (2016) 22 (11): 2697–2708.
https://doi.org/10.1158/1078-0432.CCR-15-1853
Published: 31 May 2016
View article titled, Combined Antitumor Therapy with Metronomic Topotecan and Hypoxia-Activated Prodrug, Evofosfamide, in Neuroblastoma and Rhabdomyosarcoma Preclinical Models
Open the PDF for Combined Antitumor Therapy with Metronomic Topotecan and Hypoxia-Activated Prodrug, Evofosfamide, in Neuroblastoma and Rhabdomyosarcoma Preclinical Models in another window
Includes: Supplementary data
Journal Articles

Nab-Paclitaxel Is an Active Drug in Preclinical Model of Pediatric Solid Tumors

Libo Zhang, Paula Marrano, Sushil Kumar, Michael Leadley, Evelyn Elias, Paul Thorner, Sylvain Baruchel
Journal: Clinical Cancer Research
Clin Cancer Res (2013) 19 (21): 5972–5983.
https://doi.org/10.1158/1078-0432.CCR-13-1485
Published: 31 October 2013
View article titled, Nab-Paclitaxel Is an Active Drug in Preclinical Model of Pediatric Solid Tumors
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Includes: Supplementary data
Journal Articles

Metronomic Oral Topotecan with Pazopanib Is an Active Antiangiogenic Regimen in Mouse Models of Aggressive Pediatric Solid Tumor

Sushil Kumar, Reza Bayat Mokhtari, Reihaneh Sheikh, Bing Wu, Libo Zhang, Ping Xu, Shan Man, Indhira Dias Oliveira, Herman Yeger, Robert S. Kerbel, Sylvain Baruchel
Journal: Clinical Cancer Research
Clin Cancer Res (2011) 17 (17): 5656–5667.
https://doi.org/10.1158/1078-0432.CCR-11-0078
Published: 01 September 2011
View article titled, Metronomic Oral Topotecan with Pazopanib Is an Active Antiangiogenic Regimen in Mouse Models of Aggressive Pediatric Solid Tumor
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Journal Articles

Resistance to Chemotherapy Is Associated with Fibroblast Growth Factor Receptor 4 Up-Regulation

Andreas Roidl, Hans-Jürgen Berger, Sushil Kumar, Johannes Bange, Pjotr Knyazev, Axel Ullrich
Journal: Clinical Cancer Research
Clin Cancer Res (2009) 15 (6): 2058–2066.
https://doi.org/10.1158/1078-0432.CCR-08-0890
Published: 16 March 2009
View article titled, Resistance to Chemotherapy Is Associated with Fibroblast Growth Factor Receptor 4 Up-Regulation
Open the PDF for Resistance to Chemotherapy Is Associated with Fibroblast Growth Factor Receptor 4 Up-Regulation in another window
Includes: Supplementary data