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Susan M. Chang
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Journal Articles

Glioblastoma Clinical Trials: Current Landscape and Opportunities for Improvement

Available to Purchase
Stephen J. Bagley, Shawn Kothari, Rifaquat Rahman, Eudocia Q. Lee, Gavin P. Dunn, Evanthia Galanis, Susan M. Chang, Louis Burt Nabors, Manmeet S. Ahluwalia, Roger Stupp, Minesh P. Mehta, David A. Reardon, Stuart A. Grossman, Erik P. Sulman, John H. Sampson, Simon Khagi, Michael Weller, Timothy F. Cloughesy, Patrick Y. Wen, Mustafa Khasraw
Journal: Clinical Cancer Research
Clin Cancer Res (2022) 28 (4): 594–602.
https://doi.org/10.1158/1078-0432.CCR-21-2750
Published: 15 February 2022
View article titled, Glioblastoma Clinical Trials: Current Landscape and Opportunities for Improvement
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Journal Articles

Designing Clinical Trials for Combination Immunotherapy: A Framework for Glioblastoma

Open Access
Kirit Singh, Kristen A. Batich, Patrick Y. Wen, Aaron C. Tan, Stephen J. Bagley, Michael Lim, Michael Platten, Howard Colman, David M. Ashley, Susan M. Chang, Rifaquat Rahman, Evanthia Galanis, Alireza Mansouri, Vinay K. Puduvalli, David A. Reardon, Solmaz Sahebjam, John H. Sampson, John Simes, Donald A. Berry, Gelareh Zadeh, Tim F. Cloughesy, Minesh P. Mehta, Steven Piantadosi, Michael Weller, Amy B. Heimberger, Mustafa Khasraw
Journal: Clinical Cancer Research
Clin Cancer Res (2022) 28 (4): 585–593.
https://doi.org/10.1158/1078-0432.CCR-21-2681
Published: 15 February 2022
View article titled, Designing Clinical Trials for Combination Immunotherapy: A Framework for Glioblastoma
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Journal Articles

Adaptive Global Innovative Learning Environment for Glioblastoma: GBM AGILE

Free
Brian M. Alexander, Sujuan Ba, Mitchel S. Berger, Donald A. Berry, Webster K. Cavenee, Susan M. Chang, Timothy F. Cloughesy, Tao Jiang, Mustafa Khasraw, Wenbin Li, Robert Mittman, George H. Poste, Patrick Y. Wen, W.K. Alfred Yung, Anna D. Barker
Journal: Clinical Cancer Research
Series: Author Choice
Clin Cancer Res (2018) 24 (4): 737–743.
https://doi.org/10.1158/1078-0432.CCR-17-0764
Published: 14 February 2018
View article titled, Adaptive Global Innovative Learning Environment for Glioblastoma: GBM AGILE
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Journal Articles

Prospective Feasibility Trial for Genomics-Informed Treatment in Recurrent and Progressive Glioblastoma

Free
Sara A. Byron, Nhan L. Tran, Rebecca F. Halperin, Joanna J. Phillips, John G. Kuhn, John F. de Groot, Howard Colman, Keith L. Ligon, Patrick Y. Wen, Timothy F. Cloughesy, Ingo K. Mellinghoff, Nicholas A. Butowski, Jennie W. Taylor, Jennifer L. Clarke, Susan M. Chang, Mitchel S. Berger, Annette M. Molinaro, Gerald M. Maggiora, Sen Peng, Sara Nasser, Winnie S. Liang, Jeffrey M. Trent, Michael E. Berens, John D. Carpten, David W. Craig, Michael D. Prados
Journal: Clinical Cancer Research
Clin Cancer Res (2018) 24 (2): 295–305.
https://doi.org/10.1158/1078-0432.CCR-17-0963
Published: 15 January 2018
View article titled, Prospective Feasibility Trial for Genomics-Informed Treatment in Recurrent and Progressive Glioblastoma
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Includes: Supplementary data
Journal Articles

Individual Patient-Specific Immunity against High-Grade Glioma after Vaccination with Autologous Tumor Derived Peptides Bound to the 96 KD Chaperone Protein

Free
Courtney A. Crane, Seunggu J. Han, Brian Ahn, Jessica Oehlke, Valerie Kivett, Anne Fedoroff, Nicholas Butowski, Susan M. Chang, Jennifer Clarke, Mitchel S. Berger, Michael W. McDermott, Michael D. Prados, Andrew T. Parsa
Journal: Clinical Cancer Research
Clin Cancer Res (2013) 19 (1): 205–214.
https://doi.org/10.1158/1078-0432.CCR-11-3358
Published: 02 January 2013
View article titled, Individual Patient-Specific Immunity against High-Grade Glioma after Vaccination with Autologous Tumor Derived Peptides Bound to the 96 KD Chaperone Protein
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Includes: Supplementary data
Journal Articles

Phase I Study of Vorinostat in Combination with Temozolomide in Patients with High-Grade Gliomas: North American Brain Tumor Consortium Study 04-03

Free
Eudocia Q. Lee, Vinay K. Puduvalli, Joel M. Reid, John G. Kuhn, Kathleen R. Lamborn, Timothy F. Cloughesy, Susan M. Chang, Jan Drappatz, W. K. Alfred Yung, Mark R. Gilbert, H. Ian Robins, Frank S. Lieberman, Andrew B. Lassman, Renee M. McGovern, Jihong Xu, Serena Desideri, Xiabu Ye, Matthew M. Ames, Igor Espinoza-Delgado, Michael D. Prados, Patrick Y. Wen
Journal: Clinical Cancer Research
Clin Cancer Res (2012) 18 (21): 6032–6039.
https://doi.org/10.1158/1078-0432.CCR-12-1841
Published: 06 November 2012
View article titled, Phase I Study of Vorinostat in Combination with Temozolomide in Patients with High-Grade Gliomas: North American Brain Tumor Consortium Study 04-03
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Includes: Supplementary data
Journal Articles

SSBP2 Variants Are Associated with Survival in Glioblastoma Patients

Free
Yuanyuan Xiao, Paul A. Decker, Terri Rice, Lucie S. McCoy, Ivan Smirnov, Joseph S. Patoka, Helen M. Hansen, Joe L. Wiemels, Tarik Tihan, Michael D. Prados, Susan M. Chang, Mitchel S. Berger, Matthew L. Kosel, Brooke L. Fridley, Daniel H. Lachance, Brian Patrick O'Neill, Jan C. Buckner, Reid C. Thompson, Louis Burt Nabors, Jeffrey J. Olson, Steve Brem, Melissa H. Madden, James E. Browning, John K. Wiencke, Kathleen M. Egan, Robert B. Jenkins, Margaret R. Wrensch
Journal: Clinical Cancer Research
Clin Cancer Res (2012) 18 (11): 3154–3162.
https://doi.org/10.1158/1078-0432.CCR-11-2778
Published: 31 May 2012
View article titled, SSBP2 Variants Are Associated with Survival in Glioblastoma Patients
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Includes: Supplementary data
Journal Articles

Pharmacokinetic and Tumor Distribution Characteristics of Temsirolimus in Patients with Recurrent Malignant Glioma

Free
John G. Kuhn, Susan M. Chang, Patrick Y. Wen, Timothy F. Cloughesy, Harry Greenberg, David Schiff, Charles Conrad, Karen L. Fink, H. Ian Robins, Minesh Mehta, Lisa DeAngelis, Jeffrey Raizer, Kenneth Hess, Kathleen R. Lamborn, Janet Dancey, Michael D. Prados, for the North American Brain Tumor Consortium and the National Cancer Institute
Journal: Clinical Cancer Research
Clin Cancer Res (2007) 13 (24): 7401–7406.
https://doi.org/10.1158/1078-0432.CCR-07-0781
Published: 19 December 2007
View article titled, Pharmacokinetic and Tumor Distribution Characteristics of Temsirolimus in Patients with Recurrent Malignant Glioma
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Journal Articles

Phase I Study of Temozolomide and Irinotecan for Recurrent Malignant Gliomas in Patients Receiving Enzyme-Inducing Antiepileptic Drugs: A North American Brain Tumor Consortium Study

Free
Monica E. Loghin, Michael D. Prados, Patrick Wen, Larry Junck, Frank Lieberman, Howard Fine, Karen L. Fink, Minesh Metha, John Kuhn, Kathleen Lamborn, Susan M. Chang, Timothy Cloughesy, Lisa M. DeAngelis, Ian H. Robins, Kenneth D. Aldape, W.K. Alfred Yung
Journal: Clinical Cancer Research
Clin Cancer Res (2007) 13 (23): 7133–7138.
https://doi.org/10.1158/1078-0432.CCR-07-0874
Published: 03 December 2007
View article titled, Phase I Study of Temozolomide and Irinotecan for Recurrent Malignant Gliomas in Patients Receiving Enzyme-Inducing Antiepileptic Drugs: A North American Brain Tumor Consortium Study
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Journal Articles

Phase III Randomized Study of Postradiotherapy Chemotherapy with α-Difluoromethylornithine-Procarbazine, N-(2-Chloroethyl)-N′-cyclohexyl-N-nitrosurea, Vincristine (DFMO-PCV) Versus PCV for Glioblastoma Multiforme

Free
Victor A. Levin, Joon H. Uhm, Kurt A. Jaeckle, Ali Choucair, Patrick J. Flynn, W. K. Alfred Yung, Michael D. Prados, Janet M. Bruner, Susan M. Chang, Athanassios P. Kyritsis, Mary Jo Gleason, Kenneth R. Hess
Journal: Clinical Cancer Research
Clin Cancer Res (2000) 6 (10): 3878–3884.
Published: 01 October 2000
View article titled, Phase III Randomized Study of Postradiotherapy Chemotherapy with α-Difluoromethylornithine-Procarbazine, N-(2-Chloroethyl)-N′-cyclohexyl-N-nitrosurea, Vincristine (DFMO-PCV) Versus PCV for Glioblastoma Multiforme
Open the PDF for Phase III Randomized Study of Postradiotherapy Chemotherapy with α-Difluoromethylornithine-Procarbazine, N-(2-Chloroethyl)-N′-cyclohexyl-N-nitrosurea, Vincristine (DFMO-PCV) Versus PCV for Glioblastoma Multiforme in another window