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Erlotinib, Erlotinib–Sulindac versus Placebo: A Randomized, Double-Blind, Placebo-Controlled Window Trial in Operable Head and Neck Cancer

Neil D. Gross, Julie E. Bauman, William E. Gooding, William Denq, Sufi M. Thomas, Lin Wang, Simion Chiosea, Brian L. Hood, Melanie S. Flint, Mai Sun, Thomas P. Conrads, Robert L. Ferris, Jonas T. Johnson, Seungwon Kim, Athanassios Argiris, Lori Wirth, Marina N. Nikiforova, Jill M. Siegfried, Jennifer R. Grandis

Clin Cancer Res (2014) 20 (12): 3289–3298.

DOI: https://doi.org/10.1158/1078-0432.CCR-13-3360

Published: 12 June 2014

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Includes: Supplementary data

Journal Articles

Chemoprevention of Head and Neck Cancer by Simultaneous Blocking of Epidermal Growth Factor Receptor and Cyclooxygenase-2 Signaling Pathways: Preclinical and Clinical Studies

Clin Cancer Res (2013) 19 (5): 1244–1256.

DOI: https://doi.org/10.1158/1078-0432.CCR-12-3149

Published: 03 March 2013

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Includes: Supplementary data

Journal Articles

c-Src Activation Mediates Erlotinib Resistance in Head and Neck Cancer by Stimulating c-Met

Laura P. Stabile, Guoqing He, Vivian Wai Yan Lui, Sufi M. Thomas, Cassandra Henry, Christopher T. Gubish, Sonali Joyce, Kelly M. Quesnelle, Jill M. Siegfried, Jennifer R. Grandis

Clin Cancer Res (2013) 19 (2): 380–392.

DOI: https://doi.org/10.1158/1078-0432.CCR-12-1555

Published: 16 January 2013

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Includes: Supplementary data

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Carfilzomib and ONX 0912 Inhibit Cell Survival and Tumor Growth of Head and Neck Cancer and Their Activities Are Enhanced by Suppression of Mcl-1 or Autophagy

Yan Zang, Sufi M. Thomas, Elena T. Chan, Christopher J. Kirk, Maria L. Freilino, Hannah M. DeLancey, Jennifer R. Grandis, Changyou Li, Daniel E. Johnson

Clin Cancer Res (2012) 18 (20): 5639–5649.

DOI: https://doi.org/10.1158/1078-0432.CCR-12-1213

Published: 14 October 2012

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Includes: Supplementary data

Journal Articles

Targeting Stat3 Abrogates EGFR Inhibitor Resistance in Cancer

Malabika Sen, Sonali Joyce, Mary Panahandeh, Changyou Li, Sufi M. Thomas, Jessica Maxwell, Lin Wang, William E. Gooding, Daniel E. Johnson, Jennifer R. Grandis

Clin Cancer Res (2012) 18 (18): 4986–4996.

DOI: https://doi.org/10.1158/1078-0432.CCR-12-0792

Published: 16 September 2012

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Includes: Supplementary data

Journal Articles

Targeting GPCR-Mediated p70S6K Activity May Improve Head and Neck Cancer Response to Cetuximab

Neil E. Bhola, Sufi M. Thomas, Maria Freilino, Sonali Joyce, Anirban Sahu, Jessica Maxwell, Athanassios Argiris, Raja Seethala, Jennifer R. Grandis

Clin Cancer Res (2011) 17 (15): 4996–5004.

DOI: https://doi.org/10.1158/1078-0432.CCR-10-3406

Published: 31 July 2011

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Includes: Supplementary data

Journal Articles

Honokiol Inhibits Epidermal Growth Factor Receptor Signaling and Enhances the Antitumor Effects of Epidermal Growth Factor Receptor Inhibitors

Rebecca J. Leeman-Neill, Quan Cai, Sonali C. Joyce, Sufi M. Thomas, Neil E. Bhola, Daniel B. Neill, Jack L. Arbiser, Jennifer R. Grandis

Clin Cancer Res (2010) 16 (9): 2571–2579.

DOI: https://doi.org/10.1158/1078-0432.CCR-10-0333

Published: 28 April 2010

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Journal Articles

HGF and c-Met Participate in Paracrine Tumorigenic Pathways in Head and Neck Squamous Cell Cancer

Lynn M. Knowles, Laura P. Stabile, Ann Marie Egloff, Mary E. Rothstein, Sufi M. Thomas, Christopher T. Gubish, Edwina C. Lerner, Raja R. Seethala, Shinsuke Suzuki, Kelly M. Quesnelle, Sarah Morgan, Robert L. Ferris, Jennifer R. Grandis, Jill M. Siegfried

Clin Cancer Res (2009) 15 (11): 3740–3750.

DOI: https://doi.org/10.1158/1078-0432.CCR-08-3252

Published: 01 June 2009

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Includes: Supplementary data

Journal Articles

Combined Inhibition of PLCγ-1 and c-Src Abrogates Epidermal Growth Factor Receptor–Mediated Head and Neck Squamous Cell Carcinoma Invasion

Hiroshi Nozawa, Gina Howell, Shinsuke Suzuki, Qing Zhang, Yanjun Qi, Judith Klein-Seetharaman, Alan Wells, Jennifer R. Grandis, Sufi M. Thomas

Clin Cancer Res (2008) 14 (13): 4336–4344.

DOI: https://doi.org/10.1158/1078-0432.CCR-07-4857

Published: 01 July 2008

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Journal Articles

Combined Inhibition of c-Src and Epidermal Growth Factor Receptor Abrogates Growth and Invasion of Head and Neck Squamous Cell Carcinoma

Priya Koppikar, Seung-Ho Choi, Ann Marie Egloff, Quan Cai, Shinsuke Suzuki, Maria Freilino, Hiroshi Nozawa, Sufi M. Thomas, William E. Gooding, Jill M. Siegfried, Jennifer R. Grandis

Clin Cancer Res (2008) 14 (13): 4284–4291.

DOI: https://doi.org/10.1158/1078-0432.CCR-07-5226

Published: 01 July 2008

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Journal Articles

Selective Inhibition of ADAM Metalloproteases as a Novel Approach for Modulating ErbB Pathways in Cancer

Jordan S. Fridman, Eian Caulder, Michael Hansbury, Xiangdong Liu, Genjie Yang, Qian Wang, Yvonne Lo, Bin-Bing Zhou, Maxwell Pan, Sufi M. Thomas, Jennifer R. Grandis, Jincong Zhuo, Wenqing Yao, Robert C. Newton, Steven M. Friedman, Peggy A. Scherle, Kris Vaddi

Clin Cancer Res (2007) 13 (6): 1892–1902.

DOI: https://doi.org/10.1158/1078-0432.CCR-06-2116

Published: 15 March 2007

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Journal Articles

Mutant Epidermal Growth Factor Receptor (EGFRvIII) Contributes to Head and Neck Cancer Growth and Resistance to EGFR Targeting

John C. Sok, Francesca M. Coppelli, Sufi M. Thomas, Miriam N. Lango, Sichuan Xi, Jennifer L. Hunt, Maria L. Freilino, Michael W. Graner, Carol J. Wikstrand, Darell D. Bigner, William E. Gooding, Frank B. Furnari, Jennifer R. Grandis

Clin Cancer Res (2006) 12 (17): 5064–5073.

DOI: https://doi.org/10.1158/1078-0432.CCR-06-0913

Published: 01 September 2006

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Journal Articles

Abrogation of Head and Neck Squamous Cell Carcinoma Growth by Epidermal Growth Factor Receptor Ligand Fused to Pseudomonas Exotoxin Transforming Growth Factor α-PE38

Sufi M. Thomas, Qing Zeng, Michael W. Epperly, William E. Gooding, Ira Pastan, Qing Cheng Wang, Joel Greenberger, Jennifer Rubin Grandis

Clin Cancer Res (2004) 10 (20): 7079–7087.

DOI: https://doi.org/10.1158/1078-0432.CCR-04-0587

Published: 22 October 2004

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NARROW

Erlotinib, Erlotinib–Sulindac versus Placebo: A Randomized, Double-Blind, Placebo-Controlled Window Trial in Operable Head and Neck Cancer

Chemoprevention of Head and Neck Cancer by Simultaneous Blocking of Epidermal Growth Factor Receptor and Cyclooxygenase-2 Signaling Pathways: Preclinical and Clinical Studies

c-Src Activation Mediates Erlotinib Resistance in Head and Neck Cancer by Stimulating c-Met

Carfilzomib and ONX 0912 Inhibit Cell Survival and Tumor Growth of Head and Neck Cancer and Their Activities Are Enhanced by Suppression of Mcl-1 or Autophagy

Targeting Stat3 Abrogates EGFR Inhibitor Resistance in Cancer

Targeting GPCR-Mediated p70S6K Activity May Improve Head and Neck Cancer Response to Cetuximab

Honokiol Inhibits Epidermal Growth Factor Receptor Signaling and Enhances the Antitumor Effects of Epidermal Growth Factor Receptor Inhibitors

HGF and c-Met Participate in Paracrine Tumorigenic Pathways in Head and Neck Squamous Cell Cancer

Combined Inhibition of PLCγ-1 and c-Src Abrogates Epidermal Growth Factor Receptor–Mediated Head and Neck Squamous Cell Carcinoma Invasion

Combined Inhibition of c-Src and Epidermal Growth Factor Receptor Abrogates Growth and Invasion of Head and Neck Squamous Cell Carcinoma

Selective Inhibition of ADAM Metalloproteases as a Novel Approach for Modulating ErbB Pathways in Cancer

Mutant Epidermal Growth Factor Receptor (EGFRvIII) Contributes to Head and Neck Cancer Growth and Resistance to EGFR Targeting

Abrogation of Head and Neck Squamous Cell Carcinoma Growth by Epidermal Growth Factor Receptor Ligand Fused to Pseudomonas Exotoxin Transforming Growth Factor α-PE38

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