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Stephen B. Fox
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Journal Articles

Dual Targeting of CDK4/6 and BCL2 Pathways Augments Tumor Response in Estrogen Receptor–Positive Breast Cancer

James R. Whittle, François Vaillant, Elliot Surgenor, Antonia N. Policheni, Göknur Giner, Bianca D. Capaldo, Huei-Rong Chen, He K. Liu, Johanna F. Dekkers, Norman Sachs, Hans Clevers, Andrew Fellowes, Thomas Green, Huiling Xu, Stephen B. Fox, Marco J. Herold, Gordon K. Smyth, Daniel H.D. Gray, Jane E. Visvader, Geoffrey J. Lindeman
Journal: Clinical Cancer Research
Clin Cancer Res (2020) 26 (15): 4120–4134.
https://doi.org/10.1158/1078-0432.CCR-19-1872
Published: 03 August 2020
View article titled, Dual Targeting of CDK4/6 and BCL2 Pathways Augments Tumor Response in Estrogen Receptor–Positive Breast Cancer
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Includes: Supplementary data
Journal Articles

Relationship of the Breast Ductal Carcinoma In Situ Immune Microenvironment with Clinicopathological and Genetic Features

Shona Hendry, Jia-Min B. Pang, David J. Byrne, Sunil R. Lakhani, Margaret C. Cummings, Ian G. Campbell, G. Bruce Mann, Kylie L. Gorringe, Stephen B. Fox
Journal: Clinical Cancer Research
Series: Author Choice
Clin Cancer Res (2017) 23 (17): 5210–5217.
https://doi.org/10.1158/1078-0432.CCR-17-0743
Published: 31 August 2017
View article titled, Relationship of the Breast Ductal Carcinoma <em>In Situ</em> Immune Microenvironment with Clinicopathological and Genetic Features
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Includes: Supplementary data
Journal Articles

Intra- and Interobserver Reproducibility Assessment of PD-L1 Biomarker in Non–Small Cell Lung Cancer

Wendy A. Cooper, Prudence A. Russell, Maya Cherian, Edwina E. Duhig, David Godbolt, Peter J. Jessup, Christine Khoo, Connull Leslie, Annabelle Mahar, David F. Moffat, Vanathi Sivasubramaniam, Celine Faure, Alena Reznichenko, Amanda Grattan, Stephen B. Fox
Journal: Clinical Cancer Research
Clin Cancer Res (2017) 23 (16): 4569–4577.
https://doi.org/10.1158/1078-0432.CCR-17-0151
Published: 14 August 2017
View article titled, Intra- and Interobserver Reproducibility Assessment of PD-L1 Biomarker in Non–Small Cell Lung Cancer
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Includes: Supplementary data
Journal Articles

Abstract A11: Phase II trial of letrozole (L), cyclophosphamide (C) and sorafenib (S) as neoadjuvant therapy in breast cancer patients (BC): Pharmacokinetic (PK) and pharmacodinamic (PD) analysis

Letizia Bazzola, Chiara Foroni, Daniele Andreis, Francesco Ferrozzi, Luigi Dogliotti, Alfredo Berruti, Stephen B. Fox, Adrian L. Harris, Daniele Generali, Alberto Bottini
Journal: Clinical Cancer Research
Clin Cancer Res (2010) 16 (7_Supplement): A11.
https://doi.org/10.1158/1078-0432.TCME10-A11
Published: 02 February 2016
View article titled, Abstract A11: Phase II trial of letrozole (L), cyclophosphamide (C) and sorafenib (S) as neoadjuvant therapy in breast cancer patients (BC): Pharmacokinetic (PK) and pharmacodinamic (PD) analysis
Journal Articles

The G-Protein–Coupled Receptor CLR Is Upregulated in an Autocrine Loop with Adrenomedullin in Clear Cell Renal Cell Carcinoma and Associated with Poor Prognosis

Leonid L. Nikitenko, Russell Leek, Stephen Henderson, Nischalan Pillay, Helen Turley, Daniele Generali, Sarah Gunningham, Helen R. Morrin, Andrea Pellagatti, Margaret C.P. Rees, Adrian L. Harris, Stephen B. Fox
Journal: Clinical Cancer Research
Clin Cancer Res (2013) 19 (20): 5740–5748.
https://doi.org/10.1158/1078-0432.CCR-13-1712
Published: 14 October 2013
View article titled, The G-Protein–Coupled Receptor CLR Is Upregulated in an Autocrine Loop with Adrenomedullin in Clear Cell Renal Cell Carcinoma and Associated with Poor Prognosis
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Includes: Supplementary data
Journal Articles

Immunomodulation of FOXP3+ Regulatory T Cells by the Aromatase Inhibitor Letrozole in Breast Cancer Patients

Daniele Generali, Gaynor Bates, Alfredo Berruti, Maria P. Brizzi, Leticia Campo, Simone Bonardi, Alessandra Bersiga, Giovanni Allevi, Manuela Milani, Sergio Aguggini, Luigi Dogliotti, Alison H. Banham, Adrian L. Harris, Alberto Bottini, Stephen B. Fox
Journal: Clinical Cancer Research
Clin Cancer Res (2009) 15 (3): 1046–1051.
https://doi.org/10.1158/1078-0432.CCR-08-1507
Published: 02 February 2009
View article titled, Immunomodulation of FOXP3<sup>+</sup> Regulatory T Cells by the Aromatase Inhibitor Letrozole in Breast Cancer Patients
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Includes: Supplementary data
Journal Articles

Novel Molecular Subtypes of Serous and Endometrioid Ovarian Cancer Linked to Clinical Outcome

Richard W. Tothill, Anna V. Tinker, Joshy George, Robert Brown, Stephen B. Fox, Stephen Lade, Daryl S. Johnson, Melanie K. Trivett, Dariush Etemadmoghadam, Bianca Locandro, Nadia Traficante, Sian Fereday, Jillian A. Hung, Yoke-Eng Chiew, Izhak Haviv, Australian Ovarian Cancer Study Group, Dorota Gertig, Anna deFazio, David D.L. Bowtell
Journal: Clinical Cancer Research
Clin Cancer Res (2008) 14 (16): 5198–5208.
https://doi.org/10.1158/1078-0432.CCR-08-0196
Published: 12 August 2008
View article titled, Novel Molecular Subtypes of Serous and Endometrioid Ovarian Cancer Linked to Clinical Outcome
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Includes: Supplementary data
Journal Articles

Down-Regulation of Phosphatidylinositol 3′-Kinase/AKT/Molecular Target of Rapamycin Metabolic Pathway by Primary Letrozole-Based Therapy in Human Breast Cancer

Daniele Generali, Stephen B. Fox, Maria Pia Brizzi, Giovanni Allevi, Simone Bonardi, Sergio Aguggini, Manuela Milani, Alessandra Bersiga, Leticia Campo, Rossana Dionisio, Federica Vergoni, Roberto Giardini, Luigi Dogliotti, Alberto Bottini, Adrian L. Harris, Alfredo Berruti
Journal: Clinical Cancer Research
Clin Cancer Res (2008) 14 (9): 2673–2680.
https://doi.org/10.1158/1078-0432.CCR-07-1046
Published: 01 May 2008
View article titled, Down-Regulation of Phosphatidylinositol 3′-Kinase/AKT/Molecular Target of Rapamycin Metabolic Pathway by Primary Letrozole-Based Therapy in Human Breast Cancer
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Journal Articles

BNIP3 as a Progression Marker in Primary Human Breast Cancer; Opposing Functions in In situ Versus Invasive Cancer

Ern Yu Tan, Leticia Campo, Cheng Han, Helen Turley, Francesco Pezzella, Kevin C. Gatter, Adrian L. Harris, Stephen B. Fox
Journal: Clinical Cancer Research
Clin Cancer Res (2007) 13 (2): 467–474.
https://doi.org/10.1158/1078-0432.CCR-06-1466
Published: 25 January 2007
View article titled, BNIP3 as a Progression Marker in Primary Human Breast Cancer; Opposing Functions in <em>In situ</em> Versus Invasive Cancer
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Journal Articles

Regulation of Hepatocyte Growth Factor Activator Inhibitor 2 by Hypoxia in Breast Cancer

Daniele Generali, Stephen B. Fox, Alfredo Berruti, John W. Moore, Maria Pia Brizzi, Nilay Patel, Giovanni Allevi, Simone Bonardi, Sergio Aguggini, Alessandra Bersiga, Leticia Campo, Luigi Dogliotti, Alberto Bottini, Adrian L. Harris
Journal: Clinical Cancer Research
Clin Cancer Res (2007) 13 (2): 550–558.
https://doi.org/10.1158/1078-0432.CCR-06-1266
Published: 25 January 2007
View article titled, Regulation of Hepatocyte Growth Factor Activator Inhibitor 2 by Hypoxia in Breast Cancer
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Journal Articles

Hypoxia-Inducible Factor-1α Expression Predicts a Poor Response to Primary Chemoendocrine Therapy and Disease-Free Survival in Primary Human Breast Cancer

Daniele Generali, Alfredo Berruti, Maria P. Brizzi, Leticia Campo, Simone Bonardi, Simon Wigfield, Alessandra Bersiga, Giovanni Allevi, Manuela Milani, Sergio Aguggini, Valeria Gandolfi, Luigi Dogliotti, Alberto Bottini, Adrian L. Harris, Stephen B. Fox
Journal: Clinical Cancer Research
Clin Cancer Res (2006) 12 (15): 4562–4568.
https://doi.org/10.1158/1078-0432.CCR-05-2690
Published: 09 August 2006
View article titled, Hypoxia-Inducible Factor-1α Expression Predicts a Poor Response to Primary Chemoendocrine Therapy and Disease-Free Survival in Primary Human Breast Cancer
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Journal Articles

The Androgen Receptor Is Significantly Associated with Vascular Endothelial Growth Factor and Hypoxia Sensing via Hypoxia-Inducible Factors HIF-1a, HIF-2a, and the Prolyl Hydroxylases in Human Prostate Cancer

Jane L. Boddy, Stephen B. Fox, Cheng Han, Leticia Campo, Helen Turley, Suresh Kanga, Peter R. Malone, Adrian L. Harris
Journal: Clinical Cancer Research
Clin Cancer Res (2005) 11 (21): 7658–7663.
https://doi.org/10.1158/1078-0432.CCR-05-0460
Published: 08 November 2005
View article titled, The Androgen Receptor Is Significantly Associated with Vascular Endothelial Growth Factor and Hypoxia Sensing via Hypoxia-Inducible Factors HIF-1a, HIF-2a, and the Prolyl Hydroxylases in Human Prostate Cancer
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Journal Articles

Increased Angiogenesis and Lymphangiogenesis in Inflammatory versus Noninflammatory Breast Cancer by Real-Time Reverse Transcriptase-PCR Gene Expression Quantification

Ilse Van der Auwera, Steven J. Van Laere, Gert G. Van den Eynden, Ina Benoy, Peter van Dam, Cecile G. Colpaert, Stephen B. Fox, Helen Turley, Adrian L. Harris, Eric A. Van Marck, Peter B. Vermeulen, Luc Y. Dirix
Journal: Clinical Cancer Research
Clin Cancer Res (2004) 10 (23): 7965–7971.
https://doi.org/10.1158/1078-0432.CCR-04-0063
Published: 07 December 2004
View article titled, Increased Angiogenesis and Lymphangiogenesis in Inflammatory <em>versus</em> Noninflammatory Breast Cancer by Real-Time Reverse Transcriptase-PCR Gene Expression Quantification
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Journal Articles

Expression of the Forkhead Transcription Factor FOXP1 Is Associated with Estrogen Receptor α and Improved Survival in Primary Human Breast Carcinomas

Stephen B. Fox, Philip Brown, Cheng Han, Sally Ashe, Russel D. Leek, Adrian L. Harris, Alison H. Banham
Journal: Clinical Cancer Research
Clin Cancer Res (2004) 10 (10): 3521–3527.
https://doi.org/10.1158/1078-0432.CCR-03-0461
Published: 24 May 2004
View article titled, Expression of the Forkhead Transcription Factor FOXP1 Is Associated with Estrogen Receptor α and Improved Survival in Primary Human Breast Carcinomas
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Journal Articles

Minichromosome Maintenance Protein 2 Expression in Normal Kidney and Renal Cell Carcinomas: Relationship to Tumor Dormancy and Potential Clinical Utility

Karl Rodins, Michelle Cheale, Nicholas Coleman, Stephen B. Fox
Journal: Clinical Cancer Research
Clin Cancer Res (2002) 8 (4): 1075–1081.
Published: 01 April 2002
View article titled, Minichromosome Maintenance Protein 2 Expression in Normal Kidney and Renal Cell Carcinomas: <subtitle>Relationship to Tumor Dormancy and Potential Clinical Utility</subtitle>
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Journal Articles

Angiopoietin-1 Is Inversely Related to Thymidine Phosphorylase Expression in Human Breast Cancer, Indicating a Role in Vascular Remodeling

Margaret J. Currie, Sarah P. Gunningham, Cheng Han, Prudence A. E. Scott, Bridget A. Robinson, Adrian L. Harris, Stephen B. Fox
Journal: Clinical Cancer Research
Clin Cancer Res (2001) 7 (4): 918–927.
Published: 01 April 2001
View article titled, Angiopoietin-1 Is Inversely Related to Thymidine Phosphorylase Expression in Human Breast Cancer, Indicating a Role in Vascular Remodeling
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Journal Articles

The Short Form of the Alternatively Spliced flt-4 but not Its Ligand Vascular Endothelial Growth Factor C Is Related to Lymph Node Metastasis in Human Breast Cancers

Sarah P. Gunningham, Margaret J. Currie, Cheng Han, Bridget A. Robinson, Prudence A. E. Scott, Adrian L. Harris, Stephen B. Fox
Journal: Clinical Cancer Research
Clin Cancer Res (2000) 6 (11): 4278–4286.
Published: 01 November 2000
View article titled, The Short Form of the Alternatively Spliced flt-4 but not Its Ligand Vascular Endothelial Growth Factor C Is Related to Lymph Node Metastasis in Human Breast Cancers
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