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Stephanie E. Combs
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Journal Articles

DNA-Methylome–Based Tumor Hypoxia Classifier Identifies HPV-Negative Head and Neck Cancer Patients at Risk for Locoregional Recurrence after Primary Radiochemotherapy

Bouchra Tawk, Katrin Rein, Christian Schwager, Maximilian Knoll, Ute Wirkner, Juliane Hörner-Rieber, Jakob Liermann, Ina Kurth, Panagiotis Balermpas, Claus Rödel, Annett Linge, Steffen Löck, Fabian Lohaus, Ingeborg Tinhofer, Mechtild Krause, Martin Stuschke, Anca Ligia Grosu, Daniel Zips, Stephanie E. Combs, Claus Belka, Albrecht Stenzinger, Christel Herold-Mende, Michael Baumann, Peter Schirmacher, Jürgen Debus, Amir Abdollahi
Journal: Clinical Cancer Research
Clin Cancer Res (2023) 29 (16): 3051–3064.
https://doi.org/10.1158/1078-0432.CCR-22-3790
Published: 15 August 2023
View article titled, DNA-Methylome–Based Tumor Hypoxia Classifier Identifies HPV-Negative Head and Neck Cancer Patients at Risk for Locoregional Recurrence after Primary Radiochemotherapy
Open the PDF for DNA-Methylome–Based Tumor Hypoxia Classifier Identifies HPV-Negative Head and Neck Cancer Patients at Risk for Locoregional Recurrence after Primary Radiochemotherapy in another window
Includes: Supplementary data
Journal Articles

Targeted Natural Killer Cell–Based Adoptive Immunotherapy for the Treatment of Patients with NSCLC after Radiochemotherapy: A Randomized Phase II Clinical Trial

Gabriele Multhoff, Sophie Seier, Stefan Stangl, Wolfgang Sievert, Maxim Shevtsov, Caroline Werner, A. Graham Pockley, Christiane Blankenstein, Martin Hildebrandt, Robert Offner, Norbert Ahrens, Konrad Kokowski, Matthias Hautmann, Claus Rödel, Rainer Fietkau, Dorota Lubgan, Rudolf Huber, Hubert Hautmann, Thomas Duell, Michael Molls, Hanno Specht, Bernhard Haller, Michal Devecka, Andreas Sauter, Stephanie E. Combs
Journal: Clinical Cancer Research
Series: Author Choice
Clin Cancer Res (2020) 26 (20): 5368–5379.
https://doi.org/10.1158/1078-0432.CCR-20-1141
Published: 15 October 2020
View article titled, Targeted Natural Killer Cell–Based Adoptive Immunotherapy for the Treatment of Patients with NSCLC after Radiochemotherapy: A Randomized Phase II Clinical Trial
Open the PDF for Targeted Natural Killer Cell–Based Adoptive Immunotherapy for the Treatment of Patients with NSCLC after Radiochemotherapy: A Randomized Phase II Clinical Trial in another window
Includes: Supplementary data
Journal Articles

A Five-MicroRNA Signature Predicts Survival and Disease Control of Patients with Head and Neck Cancer Negative for HPV Infection

Julia Hess, Kristian Unger, Cornelius Maihoefer, Lars Schüttrumpf, Ludmila Wintergerst, Theresa Heider, Peter Weber, Sebastian Marschner, Herbert Braselmann, Daniel Samaga, Sebastian Kuger, Ulrike Pflugradt, Philipp Baumeister, Axel Walch, Christine Woischke, Thomas Kirchner, Martin Werner, Kristin Werner, Michael Baumann, Volker Budach, Stephanie E. Combs, Jürgen Debus, Anca-Ligia Grosu, Mechthild Krause, Annett Linge, Claus Rödel, Martin Stuschke, Daniel Zips, Horst Zitzelsberger, Ute Ganswindt, Michael Henke, Claus Belka
Journal: Clinical Cancer Research
Clin Cancer Res (2019) 25 (5): 1505–1516.
https://doi.org/10.1158/1078-0432.CCR-18-0776
Published: 01 March 2019
View article titled, A Five-MicroRNA Signature Predicts Survival and Disease Control of Patients with Head and Neck Cancer Negative for HPV Infection
Open the PDF for A Five-MicroRNA Signature Predicts Survival and Disease Control of Patients with Head and Neck Cancer Negative for HPV Infection in another window
Includes: Supplementary data
Journal Articles

Development and Validation of a Gene Signature for Patients with Head and Neck Carcinomas Treated by Postoperative Radio(chemo)therapy

Stefan Schmidt, Annett Linge, Alex Zwanenburg, Stefan Leger, Fabian Lohaus, Constanze Krenn, Steffen Appold, Volker Gudziol, Alexander Nowak, Cläre von Neubeck, Inge Tinhofer, Volker Budach, Ali Sak, Martin Stuschke, Panagiotis Balermpas, Claus Rödel, Hatice Bunea, Anca-Ligia Grosu, Amir Abdollahi, Jürgen Debus, Ute Ganswindt, Claus Belka, Steffi Pigorsch, Stephanie E. Combs, David Mönnich, Daniel Zips, Gustavo B. Baretton, Frank Buchholz, Michael Baumann, Mechthild Krause, Steffen Löck
Journal: Clinical Cancer Research
Clin Cancer Res (2018) 24 (6): 1364–1374.
https://doi.org/10.1158/1078-0432.CCR-17-2345
Published: 14 March 2018
View article titled, Development and Validation of a Gene Signature for Patients with Head and Neck Carcinomas Treated by Postoperative Radio(chemo)therapy
Open the PDF for Development and Validation of a Gene Signature for Patients with Head and Neck Carcinomas Treated by Postoperative Radio(chemo)therapy in another window
Includes: Supplementary data
Journal Articles

Low Cancer Stem Cell Marker Expression and Low Hypoxia Identify Good Prognosis Subgroups in HPV(−) HNSCC after Postoperative Radiochemotherapy: A Multicenter Study of the DKTK-ROG

Annett Linge, Steffen Löck, Volker Gudziol, Alexander Nowak, Fabian Lohaus, Cläre von Neubeck, Martin Jütz, Amir Abdollahi, Jürgen Debus, Inge Tinhofer, Volker Budach, Ali Sak, Martin Stuschke, Panagiotis Balermpas, Claus Rödel, Melanie Avlar, Anca-Ligia Grosu, Christine Bayer, Claus Belka, Steffi Pigorsch, Stephanie E. Combs, Stefan Welz, Daniel Zips, Frank Buchholz, Daniela E. Aust, Gustavo B. Baretton, Howard D. Thames, Anna Dubrovska, Jan Alsner, Jens Overgaard, Michael Baumann, Mechthild Krause
Journal: Clinical Cancer Research
Clin Cancer Res (2016) 22 (11): 2639–2649.
https://doi.org/10.1158/1078-0432.CCR-15-1990
Published: 31 May 2016
View article titled, Low Cancer Stem Cell Marker Expression and Low Hypoxia Identify Good Prognosis Subgroups in HPV(−) HNSCC after Postoperative Radiochemotherapy: A Multicenter Study of the DKTK-ROG
Open the PDF for Low Cancer Stem Cell Marker Expression and Low Hypoxia Identify Good Prognosis Subgroups in HPV(−) HNSCC after Postoperative Radiochemotherapy: A Multicenter Study of the DKTK-ROG in another window
Includes: Supplementary data
Journal Articles

A Phase II, Randomized, Study of Weekly APG101+Reirradiation versus Reirradiation in Progressive Glioblastoma

Wolfgang Wick, Harald Fricke, Klaus Junge, Grigory Kobyakov, Tobias Martens, Oliver Heese, Benedikt Wiestler, Maximilian G. Schliesser, Andreas von Deimling, Josef Pichler, Elena Vetlova, Inga Harting, Jürgen Debus, Christian Hartmann, Claudia Kunz, Michael Platten, Martin Bendszus, Stephanie E. Combs
Journal: Clinical Cancer Research
Clin Cancer Res (2014) 20 (24): 6304–6313.
https://doi.org/10.1158/1078-0432.CCR-14-0951-T
Published: 14 December 2014
View article titled, A Phase II, Randomized, Study of Weekly APG101+Reirradiation versus Reirradiation in Progressive Glioblastoma
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Includes: Supplementary data
Journal Articles

Differentiation Therapy Exerts Antitumor Effects on Stem-like Glioma Cells

Benito Campos, Feng Wan, Mohammad Farhadi, Aurélie Ernst, Felix Zeppernick, Katrin E. Tagscherer, Rezvan Ahmadi, Jennifer Lohr, Christine Dictus, Georg Gdynia, Stephanie E. Combs, Violaine Goidts, Burkhard M. Helmke, Volker Eckstein, Wilfried Roth, Philipp Beckhove, Peter Lichter, Andreas Unterberg, Bernhard Radlwimmer, Christel Herold-Mende
Journal: Clinical Cancer Research
Clin Cancer Res (2010) 16 (10): 2715–2728.
https://doi.org/10.1158/1078-0432.CCR-09-1800
Published: 13 May 2010
View article titled, Differentiation Therapy Exerts Antitumor Effects on Stem-like Glioma Cells
Open the PDF for Differentiation Therapy Exerts Antitumor Effects on Stem-like Glioma Cells in another window
Includes: Supplementary data