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Steffan T. Nawrocki
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Journal Articles

Comprehensive Single-Cell Immune Profiling Defines the Patient Multiple Myeloma Microenvironment Following Oncolytic Virus Therapy in a Phase Ib Trial

Open Access
Steffan T. Nawrocki, Julian Olea, Claudia Villa Celi, Homa Dadrastoussi, Kaijin Wu, Denice Tsao-Wei, Anthony Colombo, Matt Coffey, Eduardo Fernandez Hernandez, Xuelian Chen, Gerard J. Nuovo, Jennifer S. Carew, Ann F. Mohrbacher, Paul Fields, Peter Kuhn, Imran Siddiqi, Akil Merchant, Kevin R. Kelly
Journal: Clinical Cancer Research
Clin Cancer Res (2023) 29 (24): 5087–5103.
https://doi.org/10.1158/1078-0432.CCR-23-0229
Published: 15 December 2023
View articletitled, Comprehensive Single-Cell Immune Profiling Defines the Patient Multiple Myeloma Microenvironment Following Oncolytic Virus Therapy in a Phase Ib Trial
Open the PDF for Comprehensive Single-Cell Immune Profiling Defines the Patient Multiple Myeloma Microenvironment Following Oncolytic Virus Therapy in a Phase Ib Trial in another window
Includes: Supplementary data
Journal Articles

Abstract NTOC-102: TARGETING NEDDYLATION TO OVERCOME CISPLATIN RESISTANCE IN OVARIAN CANCER

Free
Steffan T. Nawrocki, Kevin R. Kelly, Claudia M. Espitia, Jennifer S. Carew
Journal: Clinical Cancer Research
Clin Cancer Res (2017) 23 (11_Supplement): NTOC-102.
https://doi.org/10.1158/1557-3265.OVCASYMP16-NTOC-102
Published: 31 May 2017
View articletitled, Abstract NTOC-102: TARGETING NEDDYLATION TO OVERCOME CISPLATIN RESISTANCE IN OVARIAN CANCER
Journal Articles

Disruption of Autophagic Degradation with ROC-325 Antagonizes Renal Cell Carcinoma Pathogenesis

Free
Jennifer S. Carew, Claudia M. Espitia, William Zhao, Yingchun Han, Valeria Visconte, James Phillips, Steffan T. Nawrocki
Journal: Clinical Cancer Research
Clin Cancer Res (2017) 23 (11): 2869–2879.
https://doi.org/10.1158/1078-0432.CCR-16-1742
Published: 31 May 2017
View articletitled, Disruption of Autophagic Degradation with ROC-325 Antagonizes Renal Cell Carcinoma Pathogenesis
Open the PDF for Disruption of Autophagic Degradation with ROC-325 Antagonizes Renal Cell Carcinoma Pathogenesis in another window
Includes: Supplementary data
Journal Articles

The NEDD8-Activating Enzyme Inhibitor MLN4924 Disrupts Nucleotide Metabolism and Augments the Efficacy of Cytarabine

Free
Steffan T. Nawrocki, Kevin R. Kelly, Peter G. Smith, Mignon Keaton, Hetty Carraway, Mikkael A. Sekeres, Jaroslaw P. Maciejewski, Jennifer S. Carew
Journal: Clinical Cancer Research
Clin Cancer Res (2015) 21 (2): 439–447.
https://doi.org/10.1158/1078-0432.CCR-14-1960
Published: 14 January 2015
View articletitled, The NEDD8-Activating Enzyme Inhibitor MLN4924 Disrupts Nucleotide Metabolism and Augments the Efficacy of Cytarabine
Open the PDF for The NEDD8-Activating Enzyme Inhibitor MLN4924 Disrupts Nucleotide Metabolism and Augments the Efficacy of Cytarabine in another window
Includes: Supplementary data
Journal Articles

Disrupting Protein NEDDylation with MLN4924 Is a Novel Strategy to Target Cisplatin Resistance in Ovarian Cancer

Free
Steffan T. Nawrocki, Kevin R. Kelly, Peter G. Smith, Claudia M. Espitia, Anthony Possemato, Sean A. Beausoleil, Michael Milhollen, Stephen Blakemore, Michael Thomas, Allison Berger, Jennifer S. Carew
Journal: Clinical Cancer Research
Clin Cancer Res (2013) 19 (13): 3577–3590.
https://doi.org/10.1158/1078-0432.CCR-12-3212
Published: 30 June 2013
View articletitled, Disrupting Protein NEDDylation with MLN4924 Is a Novel Strategy to Target Cisplatin Resistance in Ovarian Cancer
Open the PDF for Disrupting Protein NEDDylation with MLN4924 Is a Novel Strategy to Target Cisplatin Resistance in Ovarian Cancer in another window
Includes: Supplementary data
Journal Articles

Vorinostat Enhances the Activity of Temsirolimus in Renal Cell Carcinoma Through Suppression of Survivin Levels

Free
Devalingam Mahalingam, Ernest C. Medina, Juan A. Esquivel, II, Claudia M. Espitia, Sabrina Smith, Kelli Oberheu, Ronan Swords, Kevin R. Kelly, Monica M. Mita, Alain C. Mita, Jennifer S. Carew, Francis J. Giles, Steffan T. Nawrocki
Journal: Clinical Cancer Research
Clin Cancer Res (2010) 16 (1): 141–153.
https://doi.org/10.1158/1078-0432.CCR-09-1385
Published: 04 January 2010
View articletitled, Vorinostat Enhances the Activity of Temsirolimus in Renal Cell Carcinoma Through Suppression of Survivin Levels
Open the PDF for Vorinostat Enhances the Activity of Temsirolimus in Renal Cell Carcinoma Through Suppression of Survivin Levels in another window
Journal Articles

Survivin: Key Regulator of Mitosis and Apoptosis and Novel Target for Cancer Therapeutics

Free
Alain C. Mita, Monica M. Mita, Steffan T. Nawrocki, Francis J. Giles
Journal: Clinical Cancer Research
Clin Cancer Res (2008) 14 (16): 5000–5005.
https://doi.org/10.1158/1078-0432.CCR-08-0746
Published: 12 August 2008
View articletitled, Survivin: Key Regulator of Mitosis and Apoptosis and Novel Target for Cancer Therapeutics
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