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Journal Articles

Update on Cancer Screening Recommendations for Individuals with Li–Fraumeni Syndrome

Clin Cancer Res (2025) 31 (10): 1831–1840.

https://doi.org/10.1158/1078-0432.CCR-24-3301

Published: 15 May 2025

View articletitled, Update on Cancer Screening Recommendations for Individuals with Li–Fraumeni Syndrome

Journal Articles

Update on Cancer and Central Nervous System Tumor Surveillance in Pediatric NF2-, SMARCB1-, and LZTR1-Related Schwannomatosis

Clin Cancer Res (2025) 31 (8): 1400–1406.

https://doi.org/10.1158/1078-0432.CCR-24-3278

Published: 14 April 2025

View articletitled, Update on Cancer and Central Nervous System Tumor Surveillance in Pediatric NF2-, SMARCB1-, and LZTR1-Related Schwannomatosis

Journal Articles

Clinical Characteristics and Outcomes of Central Nervous System Tumors Harboring NTRK Gene Fusions

Audrey-Anne Lamoureux, Michael J. Fisher, Lauriane Lemelle, Elke Pfaff, Pouneh Amir-Yazdani, Christof Kramm, Bram De Wilde, Bernarda Kazanowska, Caroline Hutter, Stefan M. Pfister, Dominik Sturm, David T.W. Jones, Daniel Orbach, Gaëlle Pierron, Scott Raskin, Alexander Drilon, Eli L. Diamond, Guilherme Harada, Michal Zapotocky, Josef Zamecnik, Lenka Krskova, Benjamin Ellezam, Alexander G. Weil, Dominic Venne, Marc Barritault, Pierre Leblond, Hallie Coltin, Rawan Hammad, Uri Tabori, Cynthia Hawkins, Jordan R. Hansford, Deborah Meyran, Craig Erker, Kathryn McFadden, Mariko Sato, Nicholas G. Gottardo, Hetal Dholaria, Dorte Schou Nørøxe, Hiroaki Goto, David S. Ziegler, Frank Y. Lin, Donald Williams Parsons, Holly Lindsay, Tai-Tong Wong, Yen-Lin Liu, Kuo-Sheng Wu, Andrea T. Franson, Eugene Hwang, Ana Aguilar-Bonilla, Sylvia Cheng, Chantel Cacciotti, Maura Massimino, Elisabetta Schiavello, Paul Wood, Lindsey M. Hoffman, Andréa Cappellano, Alvaro Lassaletta, An Van Damme, Anna Llort, Nicolas U. Gerber, Mariella Spalato Ceruso, Anne E. Bendel, Maggie Skrypek, Dima Hamideh, Naureen Mushtaq, Andrew Walter, Nada Jabado, Aysha Alsahlawi, Jean-Pierre Farmer, Christina Coleman, Sabine Mueller, Claire Mazewski, Dolly Aguilera, Nathan J. Robison, Katrina O’Halloran, Samuel Abbou, Pablo Berlanga, Birgit Geoerger, Ingrid Øra, Christopher L. Moertel, Evangelia D. Razis, Anastasia Vernadou, François Ducray, Charlotte Bronnimann, Romuald Seizeur, Matthew Clarke, Adam C. Resnick, Mélanie Alves, Chris Jones, François Doz, Theodore W. Laetsch, Sébastien Perreault

Clin Cancer Res (2025) 31 (3): 561–572.

https://doi.org/10.1158/1078-0432.CCR-24-0581

Published: 03 February 2025

View articletitled, Clinical Characteristics and Outcomes of Central Nervous System Tumors Harboring NTRK Gene Fusions

Includes: Supplementary data

Journal Articles

Abstract A062: Insightful analysis: Harnessing aqueous humor ctDNA for retinoblastoma stratification

Sophia H Montigel, Tatsiana Ryl, Stefanie Volz, Elena Afanasyeva, Tatjana Wedig, Nathalie Schwarz, Stefan M Pfister, Kristian W Pajtler, Petra Ketteler, Kendra K Maaß

Clin Cancer Res (2024) 30 (21_Supplement): A062.

https://doi.org/10.1158/1557-3265.LIQBIOP24-A062

Published: 13 November 2024

View articletitled, Abstract A062: Insightful analysis: Harnessing aqueous humor ctDNA for retinoblastoma stratification

Journal Articles

Abstract B012: M-PACT: Methylation-based predictive algorithm for CNS tumor liquid biopsies

Clin Cancer Res (2024) 30 (21_Supplement): B012.

https://doi.org/10.1158/1557-3265.LIQBIOP24-B012

Published: 13 November 2024

View articletitled, Abstract B012: M-PACT: Methylation-based predictive algorithm for CNS tumor liquid biopsies

Journal Articles

Update on Pediatric Cancer Surveillance Recommendations for Patients with Neurofibromatosis Type 1, Noonan Syndrome, CBL Syndrome, Costello Syndrome, and Related RASopathies

Clin Cancer Res (2024) 30 (21): 4834–4843.

https://doi.org/10.1158/1078-0432.CCR-24-1611

Published: 01 November 2024

View articletitled, Update on Pediatric Cancer Surveillance Recommendations for Patients with Neurofibromatosis Type 1, Noonan Syndrome, CBL Syndrome, Costello Syndrome, and Related RASopathies

Journal Articles

Update on Cancer Predisposition Syndromes and Surveillance Guidelines for Childhood Brain Tumors

Jordan R. Hansford, Anirban Das, Rose B. McGee, Yoshiko Nakano, Jack Brzezinski, Sarah R. Scollon, Surya P. Rednam, Jaclyn Schienda, Orli Michaeli, Sun Young Kim, Mary-Louise C. Greer, Rosanna Weksberg, Douglas R. Stewart, William D. Foulkes, Uri Tabori, Kristian W. Pajtler, Stefan M. Pfister, Garrett M. Brodeur, Junne Kamihara

Clin Cancer Res (2024) 30 (11): 2342–2350.

https://doi.org/10.1158/1078-0432.CCR-23-4033

Published: 03 June 2024

View articletitled, Update on Cancer Predisposition Syndromes and Surveillance Guidelines for Childhood Brain Tumors

Journal Articles

Clinically Tractable Outcome Prediction of Non-WNT/Non-SHH Medulloblastoma Based on TPD52 IHC in a Multicohort Study

Alberto Delaidelli, Christopher Dunham, Mariarita Santi, Gian Luca Negri, Joanna Triscott, Olga Zheludkova, Andrey Golanov, Marina Ryzhova, Konstantin Okonechnikov, Daniel Schrimpf, Damian Stichel, David W. Ellison, Andreas von Deimling, Marcel Kool, Stefan M. Pfister, Vijay Ramaswamy, Andrey Korshunov, Michael D. Taylor, Poul H. Sorensen

Clin Cancer Res (2022) 28 (1): 116–128.

https://doi.org/10.1158/1078-0432.CCR-21-2057

Published: 05 January 2022

View articletitled, Clinically Tractable Outcome Prediction of Non-WNT/Non-SHH Medulloblastoma Based on TPD52 IHC in a Multicohort Study

Includes: Supplementary data

Journal Articles

The Senescence-associated Secretory Phenotype Mediates Oncogene-induced Senescence in Pediatric Pilocytic Astrocytoma

Clin Cancer Res (2019) 25 (6): 1851–1866.

https://doi.org/10.1158/1078-0432.CCR-18-1965

Published: 15 March 2019

View articletitled, The Senescence-associated Secretory Phenotype Mediates Oncogene-induced Senescence in Pediatric Pilocytic Astrocytoma

Includes: Supplementary data

Journal Articles

A Novel Method for Rapid Molecular Subgrouping of Medulloblastoma

Clin Cancer Res (2018) 24 (6): 1355–1363.

https://doi.org/10.1158/1078-0432.CCR-17-2243

Published: 14 March 2018

View articletitled, A Novel Method for Rapid Molecular Subgrouping of Medulloblastoma

Includes: Supplementary data

Journal Articles

Recommendations for Cancer Surveillance in Individuals with RASopathies and Other Rare Genetic Conditions with Increased Cancer Risk

Anita Villani, Mary-Louise C. Greer, Jennifer M. Kalish, Akira Nakagawara, Katherine L. Nathanson, Kristian W. Pajtler, Stefan M. Pfister, Michael F. Walsh, Jonathan D. Wasserman, Kristin Zelley, Christian P. Kratz

Clin Cancer Res (2017) 23 (12): e83–e90.

https://doi.org/10.1158/1078-0432.CCR-17-0631

Published: 14 June 2017

View articletitled, Recommendations for Cancer Surveillance in Individuals with RASopathies and Other Rare Genetic Conditions with Increased Cancer Risk

Journal Articles

Cancer Screening Recommendations for Individuals with Li-Fraumeni Syndrome

Clin Cancer Res (2017) 23 (11): e38–e45.

https://doi.org/10.1158/1078-0432.CCR-17-0408

Published: 31 May 2017

View articletitled, Cancer Screening Recommendations for Individuals with Li-Fraumeni Syndrome

Journal Articles

Abstract A25: Establishment of orthotopic patient-derived xenograft models of pediatric brain tumors – the Heidelberg experience

Norman L. Mack, Sebastian Brabetz, Florian Selt, Xanthopolous Christina, David Sumerauer, Heidi Bächli, Arnulf Pekrun, Martin U. Schuhmann, Stefan M. Pfister, Olaf Witt, Till Milde, Marcel Kool

Clin Cancer Res (2016) 22 (16_Supplement): A25.

https://doi.org/10.1158/1557-3265.PDX16-A25

Published: 15 August 2016

View articletitled, Abstract A25: Establishment of orthotopic patient-derived xenograft models of pediatric brain tumors – the Heidelberg experience

Journal Articles

Abstract A07: Molecular characterization of patient-derived xenograft models of pediatric brain tumors

Sebastian Brabetz, Huriye Seker-Cin, Susanne N. Gröbner, Norman L. Mack, Volker Hovestadt, David T. W. Jones, Till Milde, Madison T. Wise, Jessica M. Rusert, Kyle Pedro, Karina Bloom, Xiao-Nan Li, Robert J. Wechsler-Reya, James M. Olson, Stefan M. Pfister, Marcel Kool

Clin Cancer Res (2016) 22 (16_Supplement): A07.

https://doi.org/10.1158/1557-3265.PDX16-A07

Published: 15 August 2016

View articletitled, Abstract A07: Molecular characterization of patient-derived xenograft models of pediatric brain tumors

Journal Articles

Abstract B37: Chemi-genomic analysis of patient-derived xenografts to identify personalized therapies for medulloblastoma

Jessica M. Rusert, Alexandra Garancher, Yoko T. Udaka, Sebastian Brabetz, Lourdes A. Esparza, Huriye Seker-Cin, Lin Qi, Mari Kogiso, Simone Schubert, Till Milde, Yoon-Jae Cho, Xiao-Nan Li, James M. Olson, John R. Crawford, Michael L. Levy, Marcel Kool, Stefan M. Pfister, Robert J. Wechsler-Reya

Clin Cancer Res (2016) 22 (16_Supplement): B37.

https://doi.org/10.1158/1557-3265.PDX16-B37

Published: 15 August 2016

View articletitled, Abstract B37: Chemi-genomic analysis of patient-derived xenografts to identify personalized therapies for medulloblastoma

Journal Articles

Abstract 11: Advancing methylation profiling in neuropathology: Diagnosis and clinical management

Clin Cancer Res (2016) 22 (1_Supplement): 11.

https://doi.org/10.1158/1557-3265.PMSCLINGEN15-11

Published: 03 January 2016

View articletitled, Abstract 11: Advancing methylation profiling in neuropathology: Diagnosis and clinical management

Journal Articles

Spinal Myxopapillary Ependymomas Demonstrate a Warburg Phenotype

Clin Cancer Res (2015) 21 (16): 3750–3758.

https://doi.org/10.1158/1078-0432.CCR-14-2650

Published: 13 August 2015

View articletitled, Spinal Myxopapillary Ependymomas Demonstrate a Warburg Phenotype

Includes: Supplementary data

Journal Articles

Molecular Characterization of Choroid Plexus Tumors Reveals Novel Clinically Relevant Subgroups

Clin Cancer Res (2015) 21 (1): 184–192.

https://doi.org/10.1158/1078-0432.CCR-14-1324

Published: 05 January 2015

View articletitled, Molecular Characterization of Choroid Plexus Tumors Reveals Novel Clinically Relevant Subgroups

Includes: Supplementary data

Journal Articles

Molecular Insights into Pediatric Brain Tumors Have the Potential to Transform Therapy

Amar Gajjar, Stefan M. Pfister, Michael D. Taylor, Richard J. Gilbertson

Clin Cancer Res (2014) 20 (22): 5630–5640.

https://doi.org/10.1158/1078-0432.CCR-14-0833

Published: 13 November 2014

View articletitled, Molecular Insights into Pediatric Brain Tumors Have the Potential to Transform Therapy

Journal Articles

PID1 (NYGGF4), a New Growth-Inhibitory Gene in Embryonal Brain Tumors and Gliomas

Anat Erdreich-Epstein, Nathan Robison, Xiuhai Ren, Hong Zhou, Jingying Xu, Tom B. Davidson, Mathew Schur, Floyd H. Gilles, Lingyun Ji, Jemily Malvar, Gregory M. Shackleford, Ashley S. Margol, Mark D. Krieger, Alexander R. Judkins, David T.W. Jones, Stefan M. Pfister, Marcel Kool, Richard Sposto, Shahab Asgharazadeh

Clin Cancer Res (2014) 20 (4): 827–836.

https://doi.org/10.1158/1078-0432.CCR-13-2053

Published: 16 February 2014

View articletitled, PID1 (NYGGF4), a New Growth-Inhibitory Gene in Embryonal Brain Tumors and Gliomas

Includes: Supplementary data

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Update on Cancer Screening Recommendations for Individuals with Li–Fraumeni Syndrome

Update on Cancer and Central Nervous System Tumor Surveillance in Pediatric NF2-, SMARCB1-, and LZTR1-Related Schwannomatosis

Clinical Characteristics and Outcomes of Central Nervous System Tumors Harboring NTRK Gene Fusions

Abstract A062: Insightful analysis: Harnessing aqueous humor ctDNA for retinoblastoma stratification

Abstract B012: M-PACT: Methylation-based predictive algorithm for CNS tumor liquid biopsies

Update on Pediatric Cancer Surveillance Recommendations for Patients with Neurofibromatosis Type 1, Noonan Syndrome, CBL Syndrome, Costello Syndrome, and Related RASopathies

Update on Cancer Predisposition Syndromes and Surveillance Guidelines for Childhood Brain Tumors

Clinically Tractable Outcome Prediction of Non-WNT/Non-SHH Medulloblastoma Based on TPD52 IHC in a Multicohort Study

The Senescence-associated Secretory Phenotype Mediates Oncogene-induced Senescence in Pediatric Pilocytic Astrocytoma

A Novel Method for Rapid Molecular Subgrouping of Medulloblastoma

Recommendations for Cancer Surveillance in Individuals with RASopathies and Other Rare Genetic Conditions with Increased Cancer Risk

Cancer Screening Recommendations for Individuals with Li-Fraumeni Syndrome

Abstract A25: Establishment of orthotopic patient-derived xenograft models of pediatric brain tumors – the Heidelberg experience

Abstract A07: Molecular characterization of patient-derived xenograft models of pediatric brain tumors

Abstract B37: Chemi-genomic analysis of patient-derived xenografts to identify personalized therapies for medulloblastoma

Abstract 11: Advancing methylation profiling in neuropathology: Diagnosis and clinical management

Spinal Myxopapillary Ependymomas Demonstrate a Warburg Phenotype

Molecular Characterization of Choroid Plexus Tumors Reveals Novel Clinically Relevant Subgroups

Molecular Insights into Pediatric Brain Tumors Have the Potential to Transform Therapy

PID1 (NYGGF4), a New Growth-Inhibitory Gene in Embryonal Brain Tumors and Gliomas

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