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Stéphane Oudard
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Journal Articles

Association of Tumor Mutational Burden and PD-L1 with the Efficacy of Pembrolizumab with or without Chemotherapy versus Chemotherapy in Advanced Urothelial Carcinoma

Aude Fléchon, Rafael Morales-Barrera, Thomas Powles, Ajjai Alva, Mustafa Özgüroğlu, Tibor Csöszi, Yohann Loriot, Alejo Rodriguez-Vida, Lajos Géczi, Susanna Y. Cheng, Yves Fradet, Stéphane Oudard, Christof Vulsteke, Seyda Gunduz, Ronac Mamtani, Evan Y. Yu, Alvaro Montesa Pino, Urbano Anido, Mehmet A.N. Sendur, Gwenaelle Gravis, János Révész, Vladimir Kostorov, Olivier Huillard, Junshui Ma, Mohini Rajasagi, Amir Vajdi, Jared Lunceford, Razvan Cristescu, Kentaro Imai, Blanca Homet Moreno, Nobuaki Matsubara
Journal: Clinical Cancer Research
Clin Cancer Res (2024) 30 (23): 5353–5364.
https://doi.org/10.1158/1078-0432.CCR-23-3518
Published: 02 December 2024
View article titled, Association of Tumor Mutational Burden and PD-L1 with the Efficacy of Pembrolizumab with or without Chemotherapy versus Chemotherapy in Advanced Urothelial Carcinoma
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Includes: Supplementary data
Journal Articles

A Signal-Finding Study of Abemaciclib in Heavily Pretreated Patients with Metastatic Castration–Resistant Prostate Cancer: Results from CYCLONE 1

Neeraj Agarwal, Daniel Castellano, Teresa Alonso-Gordoa, Jose Angel Arranz Arija, Emeline Colomba, Gwenaelle Gravis, Loic Mourey, Stephane Oudard, Aude Fléchon, Macarena González, Pablo M. Rey, Michael T. Schweizer, Enrique Gallardo, Erica Johnston, Arjun Balar, Nadine Haddad, Adams K. Appiah, Karim Nacerddine, José M. Piulats
Journal: Clinical Cancer Research
Clin Cancer Res (2024) 30 (11): 2377–2383.
https://doi.org/10.1158/1078-0432.CCR-23-3436
Published: 03 June 2024
View article titled, A Signal-Finding Study of Abemaciclib in Heavily Pretreated Patients with Metastatic Castration–Resistant Prostate Cancer: Results from CYCLONE 1
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Includes: Supplementary data
Journal Articles

Belzutifan for von Hippel–Lindau Disease: Pancreatic Lesion Population of the Phase 2 LITESPARK-004 Study

Tobias Else, Eric Jonasch, Othon Iliopoulos, Kathryn E. Beckermann, Vivek Narayan, Benjamin L. Maughan, Stephane Oudard, Jodi K. Maranchie, Ane B. Iversen, Cynthia M. Goldberg, Wei Fu, Rodolfo F. Perini, Yanfang Liu, W. Marston Linehan, Ramaprasad Srinivasan
Journal: Clinical Cancer Research
Clin Cancer Res (2024) 30 (9): 1750–1757.
https://doi.org/10.1158/1078-0432.CCR-23-2592
Published: 01 May 2024
View article titled, Belzutifan for von Hippel–Lindau Disease: Pancreatic Lesion Population of the Phase 2 LITESPARK-004 Study
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Includes: Supplementary data
Journal Articles

An Enhancer Demethylator Phenotype Converged to Immune Dysfunction and Resistance to Immune Checkpoint Inhibitors in Clear-Cell Renal Cell Carcinomas

Xiaofan Lu, Yann Vano, Alexandra Helleux, Xiaoping Su, Véronique Lindner, Guillaume Davidson, Roger Mouawad, Jean-Philippe Spano, Morgan Rouprêt, Reza Elaidi, Eva Compérat, Virginie Verkarre, Chengming Sun, Christine Chevreau, Mostefa Bennamoun, Hervé Lang, Thibault Tricard, Wenxuan Cheng, Li Xu, Irwin Davidson, Fangrong Yan, Wolf Herman Fridman, Catherine Sautes-Fridman, Stéphane Oudard, Gabriel G. Malouf
Journal: Clinical Cancer Research
Clin Cancer Res (2023) 29 (7): 1279–1291.
https://doi.org/10.1158/1078-0432.CCR-22-2133
Published: 03 April 2023
View article titled, An Enhancer Demethylator Phenotype Converged to Immune Dysfunction and Resistance to Immune Checkpoint Inhibitors in Clear-Cell Renal Cell Carcinomas
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Includes: Supplementary data
Journal Articles

Plasma CD27, a Surrogate of the Intratumoral CD27–CD70 Interaction, Correlates with Immunotherapy Resistance in Renal Cell Carcinoma

Nadine Benhamouda, Ikuan Sam, Nicolas Epaillard, Alain Gey, Letuan Phan, Hang Phuong Pham, Nadège Gruel, Antonin Saldmann, Joséphine Pineau, Milena Hasan, Valentin Quiniou, Camille Nevoret, Virginie Verkarre, Valentina Libri, Sebastien Mella, Clémence Granier, Chloe Broudin, Patrice Ravel, Eléonore De Guillebon, Laetitia Mauge, Dominique Helley, Bernd Jabla, Nathalie Chaput, Laurence Albiges, Sandrine Katsahian, Julien Adam, Arnaud Mejean, Olivier Adotevi, Yann A. Vano, Stéphane Oudard, Eric Tartour
Journal: Clinical Cancer Research
Clin Cancer Res (2022) 28 (22): 4983–4994.
https://doi.org/10.1158/1078-0432.CCR-22-0905
Published: 14 November 2022
View article titled, Plasma CD27, a Surrogate of the Intratumoral CD27–CD70 Interaction, Correlates with Immunotherapy Resistance in Renal Cell Carcinoma
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Includes: Supplementary data
Journal Articles

Blood Biomarker Landscape in Patients with High-risk Nonmetastatic Castration-Resistant Prostate Cancer Treated with Apalutamide and Androgen-Deprivation Therapy as They Progress to Metastatic Disease

Matthew R. Smith, Shibu Thomas, Michael Gormley, Simon Chowdhury, David Olmos, Stéphane Oudard, Felix Y. Feng, Yashoda Rajpurohit, Karen Urtishak, Deborah S. Ricci, Brendan Rooney, Angela Lopez-Gitlitz, Margaret Yu, Alexander W. Wyatt, Mark Li, Gerhardt Attard, Eric J. Small
Journal: Clinical Cancer Research
Clin Cancer Res (2021) 27 (16): 4539–4548.
https://doi.org/10.1158/1078-0432.CCR-21-0358
Published: 15 August 2021
View article titled, Blood Biomarker Landscape in Patients with High-risk Nonmetastatic Castration-Resistant Prostate Cancer Treated with Apalutamide and Androgen-Deprivation Therapy as They Progress to Metastatic Disease
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Includes: Supplementary data
Journal Articles

Patient-Reported Outcomes from the Phase III Randomized IMmotion151 Trial: Atezolizumab + Bevacizumab versus Sunitinib in Treatment-Naïve Metastatic Renal Cell Carcinoma

Michael B. Atkins, Brian I. Rini, Robert J. Motzer, Thomas Powles, David F. McDermott, Cristina Suarez, Sergio Bracarda, Walter M. Stadler, Frede Donskov, Howard Gurney, Stephane Oudard, Motohide Uemura, Elaine T. Lam, Carsten Grüllich, Caroleen Quach, Susheela Carroll, Beiying Ding, Qian (Cindy) Zhu, Elisabeth Piault-Louis, Christina Schiff, Bernard Escudier
Journal: Clinical Cancer Research
Series: Author Choice
Clin Cancer Res (2020) 26 (11): 2506–2514.
https://doi.org/10.1158/1078-0432.CCR-19-2838
Published: 01 June 2020
View article titled, Patient-Reported Outcomes from the Phase III Randomized IMmotion151 Trial: Atezolizumab + Bevacizumab versus Sunitinib in Treatment-Naïve Metastatic Renal Cell Carcinoma
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Includes: Supplementary data
Journal Articles

A First-in-Human Phase I Study of INVAC-1, an Optimized Human Telomerase DNA Vaccine in Patients with Advanced Solid Tumors

Luis Teixeira, Jacques Medioni, Julie Garibal, Olivier Adotevi, Ludovic Doucet, Marie-Agnès Dragon Durey, Zineb Ghrieb, Jean-Jacques Kiladjian, Mara Brizard, Caroline Laheurte, Maria Wehbe, Elodie Pliquet, Marie Escande, Rémy Defrance, Stephane Culine, Stephane Oudard, Simon Wain-Hobson, Valérie Doppler, Thierry Huet, Pierre Langlade-Demoyen
Journal: Clinical Cancer Research
Clin Cancer Res (2020) 26 (3): 588–597.
https://doi.org/10.1158/1078-0432.CCR-19-1614
Published: 03 February 2020
View article titled, A First-in-Human Phase I Study of INVAC-1, an Optimized Human Telomerase DNA Vaccine in Patients with Advanced Solid Tumors
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Includes: Supplementary data
Journal Articles

Sunitinib Prior to Planned Nephrectomy in Metastatic Renal Cell Carcinoma: Angiogenesis Biomarkers Predict Clinical Outcome in the Prospective Phase II PREINSUT Trial

Laetitia Mauge, Arnaud Mejean, Laure Fournier, Helena Pereira, Marie-Christine Etienne-Grimaldi, Emeline Levionnois, Armelle Caty, Sophie Abadie-Lacourtoisie, Stéphane Culine, Sylvestre Le Moulec, Claude Linassier, Christine Théodore, Alain Ravaud, Laurence Albiges, Abel Grine, Eric Tartour, Gérard Milano, Anne-Sophie Gille, Virginie Verkarre, Dominique Helley, Stéphane Oudard
Journal: Clinical Cancer Research
Series: Author Choice
Clin Cancer Res (2018) 24 (22): 5534–5542.
https://doi.org/10.1158/1078-0432.CCR-18-1045
Published: 15 November 2018
View article titled, Sunitinib Prior to Planned Nephrectomy in Metastatic Renal Cell Carcinoma: Angiogenesis Biomarkers Predict Clinical Outcome in the Prospective Phase II PREINSUT Trial
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Includes: Supplementary data
Journal Articles

Tumor-Infiltrating and Peripheral Blood T-cell Immunophenotypes Predict Early Relapse in Localized Clear Cell Renal Cell Carcinoma

Nicolas A. Giraldo, Etienne Becht, Yann Vano, Florent Petitprez, Laetitia Lacroix, Pierre Validire, Rafael Sanchez-Salas, Alexandre Ingels, Stephane Oudard, Audrey Moatti, Benedicte Buttard, Sarah Bourass, Claire Germain, Xavier Cathelineau, Wolf H. Fridman, Catherine Sautès-Fridman
Journal: Clinical Cancer Research
Clin Cancer Res (2017) 23 (15): 4416–4428.
https://doi.org/10.1158/1078-0432.CCR-16-2848
Published: 01 August 2017
View article titled, Tumor-Infiltrating and Peripheral Blood T-cell Immunophenotypes Predict Early Relapse in Localized Clear Cell Renal Cell Carcinoma
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Includes: Supplementary data
Journal Articles

A Therapeutic Her2/neu Vaccine Targeting Dendritic Cells Preferentially Inhibits the Growth of Low Her2/neu–Expressing Tumor in HLA-A2 Transgenic Mice

Thi Tran, Mariana O. Diniz, Estelle Dransart, Alain Gey, Nathalie Merillon, Yu Chun Lone, Sylvie Godefroy, Craig Sibley, Luis CS Ferreira, Jacques Medioni, Stephane Oudard, Ludger Johannes, Eric Tartour
Journal: Clinical Cancer Research
Clin Cancer Res (2016) 22 (16): 4133–4144.
https://doi.org/10.1158/1078-0432.CCR-16-0044
Published: 14 August 2016
View article titled, A Therapeutic Her2/neu Vaccine Targeting Dendritic Cells Preferentially Inhibits the Growth of Low Her2/neu–Expressing Tumor in HLA-A2 Transgenic Mice
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Includes: Supplementary data
Journal Articles

Orchestration and Prognostic Significance of Immune Checkpoints in the Microenvironment of Primary and Metastatic Renal Cell Cancer

Nicolas A. Giraldo, Etienne Becht, Franck Pagès, Georgios Skliris, Virginie Verkarre, Yann Vano, Arnaud Mejean, Nicolas Saint-Aubert, Laetitia Lacroix, Ivo Natario, Audrey Lupo, Marco Alifano, Diane Damotte, Aurelie Cazes, Frederic Triebel, Gordon J. Freeman, Marie-Caroline Dieu-Nosjean, Stephane Oudard, Wolf H. Fridman, Catherine Sautès-Fridman
Journal: Clinical Cancer Research
Clin Cancer Res (2015) 21 (13): 3031–3040.
https://doi.org/10.1158/1078-0432.CCR-14-2926
Published: 30 June 2015
View article titled, Orchestration and Prognostic Significance of Immune Checkpoints in the Microenvironment of Primary and Metastatic Renal Cell Cancer
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Includes: Supplementary data
Journal Articles

Molecular Subtypes of Clear Cell Renal Cell Carcinoma Are Associated with Sunitinib Response in the Metastatic Setting

Benoit Beuselinck, Sylvie Job, Etienne Becht, Alexandra Karadimou, Virginie Verkarre, Gabrielle Couchy, Nicolas Giraldo, Nathalie Rioux-Leclercq, Vincent Molinié, Mathilde Sibony, Reza Elaidi, Corinne Teghom, Jean-Jacques Patard, Arnaud Méjean, Wolf Herman Fridman, Catherine Sautès-Fridman, Aurélien de Reyniès, Stéphane Oudard, Jessica Zucman-Rossi
Journal: Clinical Cancer Research
Clin Cancer Res (2015) 21 (6): 1329–1339.
https://doi.org/10.1158/1078-0432.CCR-14-1128
Published: 12 March 2015
View article titled, Molecular Subtypes of Clear Cell Renal Cell Carcinoma Are Associated with Sunitinib Response in the Metastatic Setting
Open the PDF for Molecular Subtypes of Clear Cell Renal Cell Carcinoma Are Associated with Sunitinib Response in the Metastatic Setting in another window
Includes: Supplementary data
Journal Articles

Phase I Safety and Pharmacodynamic of Inecalcitol, a Novel VDR Agonist with Docetaxel in Metastatic Castration-Resistant Prostate Cancer Patients

Jacques Medioni, Gael Deplanque, Jean-Marc Ferrero, Tristan Maurina, Jean-Michel P. Rodier, Eric Raymond, Jorge Allyon, Gerard Maruani, Pascal Houillier, Sarah Mackenzie, Stephanie Renaux, Jean-Francois Dufour-Lamartinie, Reza Elaidi, Celine Lerest, Stephane Oudard
Journal: Clinical Cancer Research
Clin Cancer Res (2014) 20 (17): 4471–4477.
https://doi.org/10.1158/1078-0432.CCR-13-3247
Published: 01 September 2014
View article titled, Phase I Safety and Pharmacodynamic of Inecalcitol, a Novel VDR Agonist with Docetaxel in Metastatic Castration-Resistant Prostate Cancer Patients
Open the PDF for Phase I Safety and Pharmacodynamic of Inecalcitol, a Novel VDR Agonist with Docetaxel in Metastatic Castration-Resistant Prostate Cancer Patients in another window
Journal Articles

Characteristics and Clinical Impacts of the Immune Environments in Colorectal and Renal Cell Carcinoma Lung Metastases: Influence of Tumor Origin

Romain Remark, Marco Alifano, Isabelle Cremer, Audrey Lupo, Marie-Caroline Dieu-Nosjean, Marc Riquet, Lucile Crozet, Hanane Ouakrim, Jeremy Goc, Aurélie Cazes, Jean-François Fléjou, Laure Gibault, Virginie Verkarre, Jean-François Régnard, Olivier-Nicolas Pagès, Stéphane Oudard, Bernhard Mlecnik, Catherine Sautès-Fridman, Wolf-Herman Fridman, Diane Damotte
Journal: Clinical Cancer Research
Clin Cancer Res (2013) 19 (15): 4079–4091.
https://doi.org/10.1158/1078-0432.CCR-12-3847
Published: 31 July 2013
View article titled, Characteristics and Clinical Impacts of the Immune Environments in Colorectal and Renal Cell Carcinoma Lung Metastases: Influence of Tumor Origin
Open the PDF for Characteristics and Clinical Impacts of the Immune Environments in Colorectal and Renal Cell Carcinoma Lung Metastases: Influence of Tumor Origin in another window
Includes: Supplementary data