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Simone Fulda
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Journal Articles

Promises and Challenges of Smac Mimetics as Cancer Therapeutics

Simone Fulda
Journal: Clinical Cancer Research
Clin Cancer Res (2015) 21 (22): 5030–5036.
https://doi.org/10.1158/1078-0432.CCR-15-0365
Published: 12 November 2015
View article titled, Promises and Challenges of Smac Mimetics as Cancer Therapeutics
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Journal Articles

Molecular Pathways: Targeting Death Receptors and Smac Mimetics

Simone Fulda
Journal: Clinical Cancer Research
Clin Cancer Res (2014) 20 (15): 3915–3920.
https://doi.org/10.1158/1078-0432.CCR-13-2376
Published: 31 July 2014
View article titled, Molecular Pathways: Targeting Death Receptors and Smac Mimetics
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Journal Articles

Molecular Pathways: Targeting Inhibitor of Apoptosis Proteins in Cancer—From Molecular Mechanism to Therapeutic Application

Simone Fulda
Journal: Clinical Cancer Research
Clin Cancer Res (2014) 20 (2): 289–295.
https://doi.org/10.1158/1078-0432.CCR-13-0227
Published: 16 January 2014
View article titled, Molecular Pathways: Targeting Inhibitor of Apoptosis Proteins in Cancer—From Molecular Mechanism to Therapeutic Application
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Journal Articles

Bortezomib Primes Glioblastoma, Including Glioblastoma Stem Cells, for TRAIL by Increasing tBid Stability and Mitochondrial Apoptosis

Thomas Unterkircher, Silvia Cristofanon, Sri Hari Krishna Vellanki, Lisa Nonnenmacher, Georg Karpel-Massler, Christian Rainer Wirtz, Klaus-Michael Debatin, Simone Fulda
Journal: Clinical Cancer Research
Clin Cancer Res (2011) 17 (12): 4019–4030.
https://doi.org/10.1158/1078-0432.CCR-11-0075
Published: 15 June 2011
View article titled, Bortezomib Primes Glioblastoma, Including Glioblastoma Stem Cells, for TRAIL by Increasing tBid Stability and Mitochondrial Apoptosis
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Journal Articles

Bortezomib Primes Neuroblastoma Cells for TRAIL-Induced Apoptosis by Linking the Death Receptor to the Mitochondrial Pathway

Ivonne Naumann, Roland Kappler, Dietrich von Schweinitz, Klaus-Michael Debatin, Simone Fulda
Journal: Clinical Cancer Research
Clin Cancer Res (2011) 17 (10): 3204–3218.
https://doi.org/10.1158/1078-0432.CCR-10-2451
Published: 15 May 2011
View article titled, Bortezomib Primes Neuroblastoma Cells for TRAIL-Induced Apoptosis by Linking the Death Receptor to the Mitochondrial Pathway
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Includes: Supplementary data
Journal Articles

Targeting Aberrant PI3K/Akt Activation by PI103 Restores Sensitivity to TRAIL-Induced Apoptosis in Neuroblastoma

Daniela Opel, Ivonne Naumann, Maxi Schneider, Daniela Bertele, Klaus-Michael Debatin, Simone Fulda
Journal: Clinical Cancer Research
Clin Cancer Res (2011) 17 (10): 3233–3247.
https://doi.org/10.1158/1078-0432.CCR-10-2530
Published: 15 May 2011
View article titled, Targeting Aberrant PI3K/Akt Activation by PI103 Restores Sensitivity to TRAIL-Induced Apoptosis in Neuroblastoma
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Includes: Supplementary data
Journal Articles

TRAIL-Induced Apoptosis Is Preferentially Mediated via TRAIL Receptor 1 in Pancreatic Carcinoma Cells and Profoundly Enhanced by XIAP Inhibitors

Dominic Stadel, Andrea Mohr, Caroline Ref, Marion MacFarlane, Shaoxia Zhou, Robin Humphreys, Max Bachem, Gerry Cohen, Peter Möller, Ralf M. Zwacka, Klaus-Michael Debatin, Simone Fulda
Journal: Clinical Cancer Research
Clin Cancer Res (2010) 16 (23): 5734–5749.
https://doi.org/10.1158/1078-0432.CCR-10-0985
Published: 06 December 2010
View article titled, TRAIL-Induced Apoptosis Is Preferentially Mediated via TRAIL Receptor 1 in Pancreatic Carcinoma Cells and Profoundly Enhanced by XIAP Inhibitors
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Includes: Supplementary data