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Simak Ali
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Journal Articles

Personalized Detection of Circulating Tumor DNA Antedates Breast Cancer Metastatic Recurrence

Raoul Charles Coombes, Karen Page, Raheleh Salari, Robert K. Hastings, Anne Armstrong, Samreen Ahmed, Simak Ali, Susan Cleator, Laura Kenny, Justin Stebbing, Mark Rutherford, Himanshu Sethi, Anna Boydell, Ryan Swenerton, Daniel Fernandez-Garcia, Kelly L.T. Gleason, Katie Goddard, David S. Guttery, Zoe J. Assaf, Hsin-Ta Wu, Prashanthi Natarajan, David A. Moore, Lindsay Primrose, Scott Dashner, Antony S. Tin, Mustafa Balcioglu, Ramya Srinivasan, Svetlana V. Shchegrova, Alexander Olson, Dina Hafez, Paul Billings, Alexey Aleshin, Farah Rehman, Bradley J. Toghill, Allison Hills, Maggie C. Louie, Cheng-Ho Jimmy Lin, Bernhard G. Zimmermann, Jaqueline A. Shaw
Journal: Clinical Cancer Research
Series: Author Choice
Clin Cancer Res (2019) 25 (14): 4255–4263.
https://doi.org/10.1158/1078-0432.CCR-18-3663
Published: 15 July 2019
View article titled, Personalized Detection of Circulating Tumor DNA Antedates Breast Cancer Metastatic Recurrence
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Includes: Supplementary data
Journal Articles

Mutation Analysis of Cell-Free DNA and Single Circulating Tumor Cells in Metastatic Breast Cancer Patients with High Circulating Tumor Cell Counts

Jacqueline A. Shaw, David S. Guttery, Allison Hills, Daniel Fernandez-Garcia, Karen Page, Brenda M. Rosales, Kate S. Goddard, Robert K. Hastings, Jinli Luo, Olivia Ogle, Laura Woodley, Simak Ali, Justin Stebbing, R. Charles Coombes
Journal: Clinical Cancer Research
Series: Author Choice
Clin Cancer Res (2017) 23 (1): 88–96.
https://doi.org/10.1158/1078-0432.CCR-16-0825
Published: 02 January 2017
View article titled, Mutation Analysis of Cell-Free DNA and Single Circulating Tumor Cells in Metastatic Breast Cancer Patients with High Circulating Tumor Cell Counts
Open the PDF for Mutation Analysis of Cell-Free DNA and Single Circulating Tumor Cells in Metastatic Breast Cancer Patients with High Circulating Tumor Cell Counts in another window
Includes: Supplementary data
Journal Articles

Expression of CDK7, Cyclin H, and MAT1 Is Elevated in Breast Cancer and Is Prognostic in Estrogen Receptor–Positive Breast Cancer

Hetal Patel, Rezvan Abduljabbar, Chun-Fui Lai, Manikandan Periyasamy, Alison Harrod, Carolina Gemma, Jennifer H. Steel, Naina Patel, Claudia Busonero, Dena Jerjees, Judit Remenyi, Sally Smith, Jennifer J. Gomm, Luca Magnani, Balázs Győrffy, Louise J. Jones, Frances Fuller-Pace, Sami Shousha, Laki Buluwela, Emad A. Rakha, Ian O. Ellis, R. Charles Coombes, Simak Ali
Journal: Clinical Cancer Research
Series: Author Choice
Clin Cancer Res (2016) 22 (23): 5929–5938.
https://doi.org/10.1158/1078-0432.CCR-15-1104
Published: 30 November 2016
View article titled, Expression of CDK7, Cyclin H, and MAT1 Is Elevated in Breast Cancer and Is Prognostic in Estrogen Receptor–Positive Breast Cancer
Open the PDF for Expression of CDK7, Cyclin H, and MAT1 Is Elevated in Breast Cancer and Is Prognostic in Estrogen Receptor–Positive Breast Cancer in another window
Includes: Supplementary data
Journal Articles

SRC3 Phosphorylation at Serine 543 Is a Positive Independent Prognostic Factor in ER-Positive Breast Cancer

Wilbert Zwart, Koen D. Flach, Bharath Rudraraju, Tarek M.A. Abdel-Fatah, Ondrej Gojis, Sander Canisius, David Moore, Ekaterina Nevedomskaya, Mark Opdam, Marjolein Droog, Ingrid Hofland, Steve Chan, Jacqui Shaw, Ian O. Ellis, R. Charles Coombes, Jason S. Carroll, Simak Ali, Carlo Palmieri
Journal: Clinical Cancer Research
Clin Cancer Res (2016) 22 (2): 479–491.
https://doi.org/10.1158/1078-0432.CCR-14-3277
Published: 14 January 2016
View article titled, SRC3 Phosphorylation at Serine 543 Is a Positive Independent Prognostic Factor in ER-Positive Breast Cancer
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Includes: Supplementary data
Journal Articles

Phosphorylation of Estrogen Receptor-α at Ser167 Is Indicative of Longer Disease-Free and Overall Survival in Breast Cancer Patients

Jie Jiang, Naveed Sarwar, David Peston, Elena Kulinskaya, Sami Shousha, R. Charles Coombes, Simak Ali
Journal: Clinical Cancer Research
Clin Cancer Res (2007) 13 (19): 5769–5776.
https://doi.org/10.1158/1078-0432.CCR-07-0822
Published: 01 October 2007
View article titled, Phosphorylation of Estrogen Receptor-α at Ser<sup>167</sup> Is Indicative of Longer Disease-Free and Overall Survival in Breast Cancer Patients
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Journal Articles

Histone Deacetylase Inhibitor Trichostatin A Represses Estrogen Receptor α-Dependent Transcription and Promotes Proteasomal Degradation of Cyclin D1 in Human Breast Carcinoma Cell Lines

John Patrick Alao, Eric W-F. Lam, Simak Ali, Laki Buluwela, Walter Bordogna, Peter Lockey, Rana Varshochi, Alexandra V. Stavropoulou, R. Charles Coombes, David M. Vigushin
Journal: Clinical Cancer Research
Clin Cancer Res (2004) 10 (23): 8094–8104.
https://doi.org/10.1158/1078-0432.CCR-04-1023
Published: 07 December 2004
View article titled, Histone Deacetylase Inhibitor Trichostatin A Represses Estrogen Receptor α-Dependent Transcription and Promotes Proteasomal Degradation of Cyclin D1 in Human Breast Carcinoma Cell Lines
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Journal Articles

Trichostatin A Is a Histone Deacetylase Inhibitor with Potent Antitumor Activity against Breast Cancer in Vivo

David M. Vigushin, Simak Ali, Paul E. Pace, Nina Mirsaidi, Kazuhiro Ito, Ian Adcock, R. Charles Coombes
Journal: Clinical Cancer Research
Clin Cancer Res (2001) 7 (4): 971–976.
Published: 01 April 2001
View article titled, Trichostatin A Is a Histone Deacetylase Inhibitor with Potent Antitumor Activity against Breast Cancer <em>in Vivo</em>
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