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Silvia Stacchiotti
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Journal Articles

A Phase I Study of FHD-609, a Heterobifunctional Degrader of Bromodomain-Containing Protein 9, in Patients with Advanced Synovial Sarcoma or SMARCB1-Deficient Tumors

Available to Purchase
J. Andrew Livingston, Jean-Yves Blay, Jonathan Trent, Claudia Valverde, Mark Agulnik, Mrinal Gounder, Axel Le Cesne, Meredith McKean, Michael J. Wagner, Silvia Stacchiotti, Samuel Agresta, Alfonso Quintás-Cardama, Sarah A. Reilly, Kathleen Healy, Denice Hickman, Tina Zhao, Alex Ballesteros-Perez, Alexis Khalil, Michael P. Collins, Jessica Piel, Kim Horrigan, Ariel Lefkovith, Scott Innis, Alexander J. Lazar, Gregory M. Cote, Andrew J. Wagner
Journal: Clinical Cancer Research
Clin Cancer Res (2025) 31 (4): 628–638.
https://doi.org/10.1158/1078-0432.CCR-24-2583
Published: 17 February 2025
View articletitled, A Phase I Study of FHD-609, a Heterobifunctional Degrader of Bromodomain-Containing Protein 9, in Patients with Advanced Synovial Sarcoma or SMARCB1-Deficient Tumors
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Includes: Supplementary data
Journal Articles

Active Surveillance in Patients with Extra-abdominal Desmoid-Type Fibromatosis: A Pooled Analysis of Three Prospective Observational Studies

Open Access
Chiara Colombo, Stefanie Hakkesteegt, Axel Le Cesne, Francesco Barretta, Jean-Yves Blay, Dirk J. Grünhagen, Nicolas Penel, Laurent Lam, Marco Fiore, Elena Palassini, Giovanni Grignani, Francesco Tolomeo, Paola Collini, Alessandra Merlini, Federica Perrone, Silvia Stacchiotti, Cornelis Verhoef, for the Dutch Grafiti Group, Sylvie Bonvalot, for the French Sarcoma Group, Alessandro Gronchi
Journal: Clinical Cancer Research
Clin Cancer Res (2025) 31 (3): 603–610.
https://doi.org/10.1158/1078-0432.CCR-24-2340
Published: 03 February 2025
View articletitled, Active Surveillance in Patients with Extra-abdominal Desmoid-Type Fibromatosis: A Pooled Analysis of Three Prospective Observational Studies
Open the PDF for Active Surveillance in Patients with Extra-abdominal Desmoid-Type Fibromatosis: A Pooled Analysis of Three Prospective Observational Studies in another window
Includes: Supplementary data
Journal Articles

GDF-15 Predicts Epithelioid Hemangioendothelioma Aggressiveness and Is Downregulated by Sirolimus through ATF4/ATF5 Suppression

Open Access
Silvia Stacchiotti, Silvia Martini, Sandro Pasquali, Anna M. Frezza, Alessia Beretta, Stefano Percio, Mara Lecchi, Monica Tortoreto, Marta Barisella, Paola Collini, Gian Paolo Dagrada, Alessandra Merlini, Paul H. Huang, Andrew Jenks, Robin L. Jones, William D. Tap, Matilde Ingrosso, Carlo Morosi, Silvia Brich, Claudia Giani, Paolo Verderio, Paolo G. Casali, Hugh Leonard, Alessandro Gronchi, Valentina Zuco, Nadia Zaffaroni
Journal: Clinical Cancer Research
Clin Cancer Res (2024) 30 (22): 5122–5137.
https://doi.org/10.1158/1078-0432.CCR-23-3991
Published: 15 November 2024
View articletitled, GDF-15 Predicts Epithelioid Hemangioendothelioma Aggressiveness and Is Downregulated by Sirolimus through ATF4/ATF5 Suppression
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Includes: Supplementary data
Journal Articles

Predictive and Dynamic Signature for Antiangiogenics in Combination with a PD1 Inhibitor in Soft-Tissue Sarcoma: Correlative Studies Linked to the IMMUNOSARC Trial

Available to Purchase
David S. Moura, Jesus M. Lopez-Marti, Iva Benesova, Carlos de Andrea, Davide di Lernia, Serena Lacerenza, Jose L. Mondaza-Hernandez, Marta Martin-Ruiz, Marta Ramirez-Calvo, Giovanni Grignani, Javier Martinez-Trufero, Andres Redondo, Claudia Valverde, Silvia Stacchiotti, Antonio Lopez-Pousa, José A. Lopez-Guerrero, Antonio Gutierrez, Victor Encinas-Tobajas, Nadia Hindi, Dario Sangiolo, Jose A. Lopez-Martin, Zuzana Ozaniak Strizova, Javier Martin-Broto
Journal: Clinical Cancer Research
Clin Cancer Res (2024) 30 (22): 5192–5206.
https://doi.org/10.1158/1078-0432.CCR-24-1782
Published: 15 November 2024
View articletitled, Predictive and Dynamic Signature for Antiangiogenics in Combination with a PD1 Inhibitor in Soft-Tissue Sarcoma: Correlative Studies Linked to the IMMUNOSARC Trial
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Includes: Supplementary data
Journal Articles

CSF1R Inhibition in Patients with Advanced Solid Tumors or Tenosynovial Giant Cell Tumor: A Phase I Study of Vimseltinib

Open Access
Hans Gelderblom, Albiruni A. Razak, Matthew H. Taylor, Todd M. Bauer, Breelyn Wilky, Javier Martin-Broto, Alejandro F. Gonzalez, Piotr Rutkowski, Bartlomiej Szostakowski, Thierry Alcindor, Ramy Saleh, Sofia Genta, Silvia Stacchiotti, Michiel van de Sande, Andrew J. Wagner, Nicholas Bernthal, Lara E. Davis, Jacqueline Vuky, Christopher Tait, Bahar Matin, Supraja Narasimhan, Maitreyi G. Sharma, Rodrigo Ruiz-Soto, Matthew L. Sherman, William D. Tap
Journal: Clinical Cancer Research
Clin Cancer Res (2024) 30 (18): 3996–4004.
https://doi.org/10.1158/1078-0432.CCR-24-0103
Published: 13 September 2024
View articletitled, CSF1R Inhibition in Patients with Advanced Solid Tumors or Tenosynovial Giant Cell Tumor: A Phase I Study of Vimseltinib
Open the PDF for CSF1R Inhibition in Patients with Advanced Solid Tumors or Tenosynovial Giant Cell Tumor: A Phase I Study of Vimseltinib in another window
Includes: Supplementary data
Journal Articles

A Prospective Observational Study of Active Surveillance in Primary Desmoid Fibromatosis

Available to Purchase
Chiara Colombo, Marco Fiore, Giovanni Grignani, Francesco Tolomeo, Alessandra Merlini, Elena Palassini, Paola Collini, Silvia Stacchiotti, Paolo Giovanni Casali, Federica Perrone, Luigi Mariani, Alessandro Gronchi
Journal: Clinical Cancer Research
Clin Cancer Res (2022) 28 (18): 4027–4032.
https://doi.org/10.1158/1078-0432.CCR-21-4205
Published: 15 September 2022
View articletitled, A Prospective Observational Study of Active Surveillance in Primary Desmoid Fibromatosis
Open the PDF for A Prospective Observational Study of Active Surveillance in Primary Desmoid Fibromatosis in another window
Includes: Supplementary data
Journal Articles

Role of Chemotherapy, VEGFR Inhibitors, and mTOR Inhibitors in Advanced Perivascular Epithelioid Cell Tumors (PEComas)

Free
Roberta Sanfilippo, Robin L. Jones, Jean-Yves Blay, Axel Le Cesne, Salvatore Provenzano, Georgios Antoniou, Olivier Mir, Giovanni Fucà, Elena Fumagalli, Rossella Bertulli, Silvia Stacchiotti, Mehdi Brahmi, Federica Grosso, Armelle Dufresne, Nadia Hindi, Marta Sbaraglia, Alessandro Gronchi, Paola Collini, Angelo P. Dei Tos, Paolo G. Casali
Journal: Clinical Cancer Research
Clin Cancer Res (2019) 25 (17): 5295–5300.
https://doi.org/10.1158/1078-0432.CCR-19-0288
Published: 03 September 2019
View articletitled, Role of Chemotherapy, VEGFR Inhibitors, and mTOR Inhibitors in Advanced Perivascular Epithelioid Cell Tumors (PEComas)
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Includes: Supplementary data
Journal Articles

Efficacy and Biological Activity of Imatinib in Metastatic Dermatofibrosarcoma Protuberans (DFSP)

Free
Silvia Stacchiotti, Maria A. Pantaleo, Tiziana Negri, Annalisa Astolfi, Marcella Tazzari, Gian Paolo Dagrada, Milena Urbini, Valentina Indio, Roberta Maestro, Alessandro Gronchi, Marco Fiore, Angelo P. Dei Tos, Elena Conca, Elena Palassini, Bruno Vincenzi, Federica Grosso, Silvana Pilotti, Chiara Castelli, Paolo G. Casali
Journal: Clinical Cancer Research
Clin Cancer Res (2016) 22 (4): 837–846.
https://doi.org/10.1158/1078-0432.CCR-15-1243
Published: 14 February 2016
View articletitled, Efficacy and Biological Activity of Imatinib in Metastatic Dermatofibrosarcoma Protuberans (DFSP)
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Includes: Supplementary data
Journal Articles

Response to Sunitinib Malate in Advanced Alveolar Soft Part Sarcoma

Free
Silvia Stacchiotti, Elena Tamborini, Andrea Marrari, Silvia Brich, Sara Arisi Rota, Marta Orsenigo, Flavio Crippa, Carlo Morosi, Alessandro Gronchi, Marco A. Pierotti, Paolo G. Casali, Silvana Pilotti
Journal: Clinical Cancer Research
Clin Cancer Res (2009) 15 (3): 1096–1104.
https://doi.org/10.1158/1078-0432.CCR-08-2050
Published: 02 February 2009
View articletitled, Response to Sunitinib Malate in Advanced Alveolar Soft Part Sarcoma
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Journal Articles

Molecular and Biochemical Analyses of Platelet-Derived Growth Factor Receptor (PDGFR) B, PDGFRA, and KIT Receptors in Chordomas

Free
Elena Tamborini, Francesca Miselli, Tiziana Negri, M. Stefania Lagonigro, Samantha Staurengo, Gian Paolo Dagrada, Silvia Stacchiotti, Elisa Pastore, Alessandro Gronchi, Federica Perrone, Antonino Carbone, Marco A. Pierotti, Paolo G. Casali, Silvana Pilotti
Journal: Clinical Cancer Research
Clin Cancer Res (2006) 12 (23): 6920–6928.
https://doi.org/10.1158/1078-0432.CCR-06-1584
Published: 04 December 2006
View articletitled, Molecular and Biochemical Analyses of Platelet-Derived Growth Factor Receptor (PDGFR) B, PDGFRA, and KIT Receptors in Chordomas
Open the PDF for Molecular and Biochemical Analyses of Platelet-Derived Growth Factor Receptor (PDGFR) B, PDGFRA, and KIT Receptors in Chordomas in another window