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Journal Articles

Regulation of OATP1B1 Function by Tyrosine Kinase–mediated Phosphorylation

Elizabeth R. Hayden, Mingqing Chen, Kyle Z. Pasquariello, Alice A. Gibson, James J. Petti, Shichen Shen, Jun Qu, Su Sien Ong, Taosheng Chen, Yan Jin, Muhammad Erfan Uddin, Kevin M. Huang, Aviv Paz, Alex Sparreboom, Shuiying Hu, Jason A. Sprowl
Journal: Clinical Cancer Research
Clin Cancer Res (2021) 27 (15): 4301–4310.
https://doi.org/10.1158/1078-0432.CCR-21-0023
Published: 01 August 2021
View article titled, Regulation of OATP1B1 Function by Tyrosine Kinase–mediated Phosphorylation
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Includes: Supplementary data
Journal Articles

Recent Developments of Novel Pharmacologic Therapeutics for Prevention of Chemotherapy-Induced Peripheral Neuropathy

Shuiying Hu, Kevin M. Huang, Elizabeth J. Adams, Charles L. Loprinzi, Maryam B. Lustberg
Journal: Clinical Cancer Research
Clin Cancer Res (2019) 25 (21): 6295–6301.
https://doi.org/10.1158/1078-0432.CCR-18-2152
Published: 01 November 2019
View article titled, Recent Developments of Novel Pharmacologic Therapeutics for Prevention of Chemotherapy-Induced Peripheral Neuropathy
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Journal Articles

Cellular Uptake of Imatinib into Leukemic Cells Is Independent of Human Organic Cation Transporter 1 (OCT1)

Anne T. Nies, Elke Schaeffeler, Heiko van der Kuip, Ingolf Cascorbi, Oliver Bruhn, Michael Kneba, Christiane Pott, Ute Hofmann, Christopher Volk, Shuiying Hu, Sharyn D. Baker, Alex Sparreboom, Peter Ruth, Hermann Koepsell, Matthias Schwab
Journal: Clinical Cancer Research
Clin Cancer Res (2014) 20 (4): 985–994.
https://doi.org/10.1158/1078-0432.CCR-13-1999
Published: 16 February 2014
View article titled, Cellular Uptake of Imatinib into Leukemic Cells Is Independent of Human Organic Cation Transporter 1 (OCT1)
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Includes: Supplementary data
Journal Articles

Contribution of Abcc4-Mediated Gastric Transport to the Absorption and Efficacy of Dasatinib

Brian D. Furmanski, Shuiying Hu, Ken-ichi Fujita, Lie Li, Alice A. Gibson, Laura J. Janke, Richard T. Williams, John D. Schuetz, Alex Sparreboom, Sharyn D. Baker
Journal: Clinical Cancer Research
Clin Cancer Res (2013) 19 (16): 4359–4370.
https://doi.org/10.1158/1078-0432.CCR-13-0980
Published: 13 August 2013
View article titled, Contribution of Abcc4-Mediated Gastric Transport to the Absorption and Efficacy of Dasatinib
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Includes: Supplementary data
Journal Articles

Contribution of OATP1B1 and OATP1B3 to the Disposition of Sorafenib and Sorafenib-Glucuronide

Eric I. Zimmerman, Shuiying Hu, Justin L. Roberts, Alice A. Gibson, Shelley J. Orwick, Lie Li, Alex Sparreboom, Sharyn D. Baker
Journal: Clinical Cancer Research
Clin Cancer Res (2013) 19 (6): 1458–1466.
https://doi.org/10.1158/1078-0432.CCR-12-3306
Published: 14 March 2013
View article titled, Contribution of OATP1B1 and OATP1B3 to the Disposition of Sorafenib and Sorafenib-Glucuronide
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Includes: Supplementary data
Journal Articles

Phase I and Clinical Pharmacology Study of Bevacizumab, Sorafenib, and Low-Dose Cyclophosphamide in Children and Young Adults with Refractory/Recurrent Solid Tumors

Fariba Navid, Sharyn D. Baker, M. Beth McCarville, Clinton F. Stewart, Catherine A. Billups, Jianrong Wu, Andrew M. Davidoff, Sheri L. Spunt, Wayne L. Furman, Lisa M. McGregor, Shuiying Hu, John C. Panetta, David Turner, Demba Fofana, Wilburn E. Reddick, Wing Leung, Victor M. Santana
Journal: Clinical Cancer Research
Clin Cancer Res (2013) 19 (1): 236–246.
https://doi.org/10.1158/1078-0432.CCR-12-1897
Published: 02 January 2013
View article titled, Phase I and Clinical Pharmacology Study of Bevacizumab, Sorafenib, and Low-Dose Cyclophosphamide in Children and Young Adults with Refractory/Recurrent Solid Tumors
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Journal Articles

Influence of Polymorphic OATP1B-Type Carriers on the Disposition of Docetaxel

Anne-Joy M. de Graan, Cynthia S. Lancaster, Amanda Obaidat, Bruno Hagenbuch, Laure Elens, Lena E. Friberg, Peter de Bruijn, Shuiying Hu, Alice A. Gibson, Gitte H. Bruun, Thomas J. Corydon, Torben S. Mikkelsen, Aisha L. Walker, Guoqing Du, Walter J. Loos, Ron H. N. van Schaik, Sharyn D. Baker, Ron H. J. Mathijssen, Alex Sparreboom
Journal: Clinical Cancer Research
Clin Cancer Res (2012) 18 (16): 4433–4440.
https://doi.org/10.1158/1078-0432.CCR-12-0761
Published: 14 August 2012
View article titled, Influence of Polymorphic OATP1B-Type Carriers on the Disposition of Docetaxel
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Includes: Supplementary data
Journal Articles

Interaction of the Multikinase Inhibitors Sorafenib and Sunitinib with Solute Carriers and ATP-Binding Cassette Transporters

Shuiying Hu, Zhaoyuan Chen, Ryan Franke, Shelley Orwick, Ming Zhao, Michelle A. Rudek, Alex Sparreboom, Sharyn D. Baker
Journal: Clinical Cancer Research
Clin Cancer Res (2009) 15 (19): 6062–6069.
https://doi.org/10.1158/1078-0432.CCR-09-0048
Published: 30 September 2009
View article titled, Interaction of the Multikinase Inhibitors Sorafenib and Sunitinib with Solute Carriers and ATP-Binding Cassette Transporters
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Includes: Supplementary data
Journal Articles

Interaction of Imatinib with Human Organic Ion Carriers

Shuiying Hu, Ryan M. Franke, Kelly K. Filipski, Chaoxin Hu, Shelley J. Orwick, Ernst A. de Bruijn, Herman Burger, Sharyn D. Baker, Alex Sparreboom
Journal: Clinical Cancer Research
Clin Cancer Res (2008) 14 (10): 3141–3148.
https://doi.org/10.1158/1078-0432.CCR-07-4913
Published: 15 May 2008
View article titled, Interaction of Imatinib with Human Organic Ion Carriers
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Journal Articles

Suppression of BRAF/MEK/MAP Kinase Pathway Restores Expression of Iodide-Metabolizing Genes in Thyroid Cells Expressing the V600E BRAF Mutant

Dingxie Liu, Shuiying Hu, Peng Hou, David Jiang, Stephen Condouris, Mingzhao Xing
Journal: Clinical Cancer Research
Clin Cancer Res (2007) 13 (4): 1341–1349.
https://doi.org/10.1158/1078-0432.CCR-06-1753
Published: 22 February 2007
View article titled, Suppression of BRAF/MEK/MAP Kinase Pathway Restores Expression of Iodide-Metabolizing Genes in Thyroid Cells Expressing the V600E BRAF Mutant
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Journal Articles

Genetic Alterations and Their Relationship in the Phosphatidylinositol 3-Kinase/Akt Pathway in Thyroid Cancer

Peng Hou, Dingxie Liu, Yuan Shan, Shuiying Hu, Kimberley Studeman, Stephen Condouris, Yangang Wang, Ariel Trink, Adel K. El-Naggar, Giovanni Tallini, Vasily Vasko, Mingzhao Xing
Journal: Clinical Cancer Research
Clin Cancer Res (2007) 13 (4): 1161–1170.
https://doi.org/10.1158/1078-0432.CCR-06-1125
Published: 22 February 2007
View article titled, Genetic Alterations and Their Relationship in the Phosphatidylinositol 3-Kinase/Akt Pathway in Thyroid Cancer
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