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Shuang G. Zhao
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Journal Articles

Abstract B042: Molecular assessment of cell surface targets using integrated circulating tumor cell (CTC) RNAseq and single CTC phenotyping

Jamie M. Sperger, Marina N. Sharifi, Katherine R. Kaufmann, Matthew L. Bootsma, Shannon R. Reese, Viridiana Carreno, Alex H. Chang, Luke A. Nunamaker, A. Nunamaker, Charlotte Linebarger, Amy K. Taylor, Katherine E Tippins, Kyle T. Helzer, Shuang G. Zhao, Joshua M Lang
Journal: Clinical Cancer Research
Clin Cancer Res (2024) 30 (21_Supplement): B042.
https://doi.org/10.1158/1557-3265.LIQBIOP24-B042
Published: 13 November 2024
View article titled, Abstract B042: Molecular assessment of cell surface targets using integrated circulating tumor cell (CTC) RNAseq and single CTC phenotyping
Journal Articles

Abstract B041: High purity CTC RNA sequencing identifies poor prognosis lineage states in castrate resistant prostate cancer

Marina N Sharifi, Jamie M Sperger, Amy K Taylor, Katharine E Tippins, Shannon R Reese, Viridiana Carreno, Katherine R Kaufmann, Alex H Chang, Luke A Nunamaker, Charlotte Linebarger, Kyle T Helzer, Matthew Bootsma, Grace C Blitzer, John Floberg, David Kosoff, Rana R McKay, Xiao X Wei, Shuang G Zhao, Joshua M Lang
Journal: Clinical Cancer Research
Clin Cancer Res (2024) 30 (21_Supplement): B041.
https://doi.org/10.1158/1557-3265.LIQBIOP24-B041
Published: 13 November 2024
View article titled, Abstract B041: High purity CTC RNA sequencing identifies poor prognosis lineage states in castrate resistant prostate cancer
Journal Articles

Abstract PR010: High purity CTC RNA sequencing identifies poor prognosis lineage states in castrate resistant prostate cancer

Marina N Sharifi, Jamie M Sperger, Amy K Taylor, Katharine E Tippins, Shannon R Reese, Viridiana Carreno, Katherine R Kaufmann, Alex H Chang, Luke A Nunamaker, Charlotte Linebarger, Kyle T Helzer, Matthew Bootsma, Grace C Blitzer, John Floberg, David Kosoff, Rana R McKay, Xiao X Wei, Shuang G Zhao, Joshua M Lang
Journal: Clinical Cancer Research
Clin Cancer Res (2024) 30 (21_Supplement): PR010.
https://doi.org/10.1158/1557-3265.LIQBIOP24-PR010
Published: 13 November 2024
View article titled, Abstract PR010: High purity CTC RNA sequencing identifies poor prognosis lineage states in castrate resistant prostate cancer
Journal Articles

Abstract B066: Analytical validation of a multiplexed CTC-mRNA assay for androgen receptor pathway inhibitors

Jennifer L Schehr, Rory M Bade, Anupama Singh, Jacob C Caceres, Nasya A Ramli, Matthew C Mannino, Diego Eyzaguirre, Alyssa M Hintz, Manushi N Vatani, Serena K Wolfe, Kayo Miyazaki, Elizabeth Haas, Joshua Faulkes, Dana E Rathkopf, Susan Halabi, Andrew J Armstrong, Shuang G Zhao, Joshua M Lang
Journal: Clinical Cancer Research
Clin Cancer Res (2024) 30 (21_Supplement): B066.
https://doi.org/10.1158/1557-3265.LIQBIOP24-B066
Published: 13 November 2024
View article titled, Abstract B066: Analytical validation of a multiplexed CTC-mRNA assay for androgen receptor pathway inhibitors
Journal Articles

Expression and Therapeutic Targeting of TROP-2 in Treatment-Resistant Prostate Cancer

Jamie M. Sperger, Kyle T. Helzer, Charlotte N. Stahlfeld, Dawei Jiang, Anupama Singh, Katherine R. Kaufmann, David J. Niles, Erika Heninger, Nicholas R. Rydzewski, Liguo Wang, Liewei Wang, Rendong Yang, Yanan Ren, Jonathan W. Engle, Peng Huang, Christos E. Kyriakopoulos, Susan F. Slovin, Howard R. Soule, Shuang G. Zhao, Manish Kohli, Scott T. Tagawa, Weibo Cai, Scott M. Dehm, Joshua M. Lang
Journal: Clinical Cancer Research
Clin Cancer Res (2023) 29 (12): 2324–2335.
https://doi.org/10.1158/1078-0432.CCR-22-1305
Published: 13 June 2023
View article titled, Expression and Therapeutic Targeting of TROP-2 in Treatment-Resistant Prostate Cancer
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Includes: Supplementary data
Journal Articles

Intrinsic Molecular Subtypes of Metastatic Castration-Resistant Prostate Cancer

Eric Feng, Nicholas R. Rydzewski, Meng Zhang, Arian Lundberg, Matthew Bootsma, Kyle T. Helzer, Joshua M. Lang, Rahul Aggarwal, Eric J. Small, David A. Quigley, Martin Sjöström, Shuang G. Zhao
Journal: Clinical Cancer Research
Clin Cancer Res (2022) 28 (24): 5396–5404.
https://doi.org/10.1158/1078-0432.CCR-22-2567
Published: 15 December 2022
View article titled, Intrinsic Molecular Subtypes of Metastatic Castration-Resistant Prostate Cancer
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Includes: Supplementary data
Journal Articles

Phase II Multicenter Study of Enzalutamide in Metastatic Castration-Resistant Prostate Cancer to Identify Mechanisms Driving Resistance

Rana R. McKay, Lucia Kwak, Jett P. Crowdis, Jamie M. Sperger, Shuang G. Zhao, Wanling Xie, Lillian Werner, Rosina T. Lis, Zhenwei Zhang, Xiao X. Wei, Joshua M. Lang, Eliezer M. Van Allen, Rupal S. Bhatt, Evan Y. Yu, Peter S. Nelson, Glenn J. Bubley, R. Bruce Montgomery, Mary-Ellen Taplin
Journal: Clinical Cancer Research
Clin Cancer Res (2021) 27 (13): 3610–3619.
https://doi.org/10.1158/1078-0432.CCR-20-4616
Published: 01 July 2021
View article titled, Phase II Multicenter Study of Enzalutamide in Metastatic Castration-Resistant Prostate Cancer to Identify Mechanisms Driving Resistance
Open the PDF for Phase II Multicenter Study of Enzalutamide in Metastatic Castration-Resistant Prostate Cancer to Identify Mechanisms Driving Resistance in another window
Includes: Supplementary data
Journal Articles

Autoantibody Landscape in Patients with Advanced Prostate Cancer

William S. Chen, Winston A. Haynes, Rebecca Waitz, Kathy Kamath, Agustin Vega-Crespo, Raunak Shrestha, Minlu Zhang, Adam Foye, Ignacio Baselga Carretero, Ivan Perez Garcilazo, Meng Zhang, Shuang G. Zhao, Martin Sjöström, David A. Quigley, Jonathan Chou, Tomasz M. Beer, Matthew Rettig, Martin Gleave, Christopher P. Evans, Primo Lara, Kim N. Chi, Robert E. Reiter, Joshi J. Alumkal, Alan Ashworth, Rahul Aggarwal, Eric J. Small, Patrick S. Daugherty, Antoni Ribas, David Y. Oh, John C. Shon, Felix Y. Feng
Journal: Clinical Cancer Research
Clin Cancer Res (2020) 26 (23): 6204–6214.
https://doi.org/10.1158/1078-0432.CCR-20-1966
Published: 01 December 2020
View article titled, Autoantibody Landscape in Patients with Advanced Prostate Cancer
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Includes: Supplementary data
Journal Articles

Transcriptomic Heterogeneity of Androgen Receptor Activity Defines a de novo low AR-Active Subclass in Treatment Naïve Primary Prostate Cancer

Daniel E. Spratt, Mohammed Alshalalfa, Nick Fishbane, Adam B. Weiner, Rohit Mehra, Brandon A. Mahal, Jonathan Lehrer, Yang Liu, Shuang G. Zhao, Corey Speers, Todd M. Morgan, Adam P. Dicker, Stephen J. Freedland, R. Jeffery Karnes, Sheila Weinmann, Elai Davicioni, Ashley E. Ross, Robert B. Den, Paul L. Nguyen, Felix Y. Feng, Tamara L. Lotan, Arul M. Chinnaiyan, Edward M. Schaeffer
Journal: Clinical Cancer Research
Clin Cancer Res (2019) 25 (22): 6721–6730.
https://doi.org/10.1158/1078-0432.CCR-19-1587
Published: 15 November 2019
View article titled, Transcriptomic Heterogeneity of Androgen Receptor Activity Defines a <em>de novo</em> low AR-Active Subclass in Treatment Naïve Primary Prostate Cancer
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Includes: Supplementary data
Journal Articles

DNA-Dependent Protein Kinase Drives Prostate Cancer Progression through Transcriptional Regulation of the Wnt Signaling Pathway

Vishal Kothari, Jonathan F. Goodwin, Shuang G. Zhao, Justin M. Drake, Yi Yin, S. Laura Chang, Joseph R. Evans, Kari Wilder-Romans, Kristina Gabbara, Emanuela Dylgjeri, Jonathan Chou, Grace Sun, Scott A. Tomlins, Rohit Mehra, Kristen Hege, Ellen H. Filvaroff, Edward M. Schaeffer, R. Jeffrey Karnes, David A. Quigley, Dana E. Rathkopf, Housheng H. He, Corey Speers, Daniel E. Spratt, Luke A. Gilbert, Alan Ashworth, Arul M. Chinnaiyan, Ganesh V. Raj, Karen E. Knudsen, Felix Y. Feng
Journal: Clinical Cancer Research
Clin Cancer Res (2019) 25 (18): 5608–5622.
https://doi.org/10.1158/1078-0432.CCR-18-2387
Published: 13 September 2019
View article titled, DNA-Dependent Protein Kinase Drives Prostate Cancer Progression through Transcriptional Regulation of the Wnt Signaling Pathway
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Journal Articles

Novel RB1-Loss Transcriptomic Signature Is Associated with Poor Clinical Outcomes across Cancer Types

William S. Chen, Mohammed Alshalalfa, Shuang G. Zhao, Yang Liu, Brandon A. Mahal, David A. Quigley, Ting Wei, Elai Davicioni, Timothy R. Rebbeck, Philip W. Kantoff, Christopher A. Maher, Karen E. Knudsen, Eric J. Small, Paul L. Nguyen, Felix Y. Feng
Journal: Clinical Cancer Research
Clin Cancer Res (2019) 25 (14): 4290–4299.
https://doi.org/10.1158/1078-0432.CCR-19-0404
Published: 15 July 2019
View article titled, Novel RB1-Loss Transcriptomic Signature Is Associated with Poor Clinical Outcomes across Cancer Types
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Includes: Supplementary data
Journal Articles

Clinical and Genomic Implications of Luminal and Basal Subtypes Across Carcinomas

Shuang G. Zhao, William S. Chen, Rajdeep Das, S. Laura Chang, Scott A. Tomlins, Jonathan Chou, David A. Quigley, Ha X. Dang, Travis J. Barnard, Brandon A. Mahal, Ewan A. Gibb, Yang Liu, Elai Davicioni, Linda R. Duska, Edwin M. Posadas, Shruti Jolly, Daniel E. Spratt, Paul L. Nguyen, Christopher A. Maher, Eric J. Small, Felix Y. Feng
Journal: Clinical Cancer Research
Clin Cancer Res (2019) 25 (8): 2450–2457.
https://doi.org/10.1158/1078-0432.CCR-18-3121
Published: 15 April 2019
View article titled, Clinical and Genomic Implications of Luminal and Basal Subtypes Across Carcinomas
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Includes: Supplementary data
Journal Articles

Development and Validation of a Prostate Cancer Genomic Signature that Predicts Early ADT Treatment Response Following Radical Prostatectomy

R. Jeffrey Karnes, Vidit Sharma, Voleak Choeurng, Hussam Al-Deen Ashab, Nicholas Erho, Mohammed Alshalalfa, Bruce Trock, Ashley Ross, Kasra Yousefi, Harrison Tsai, Shuang G. Zhao, Jeffrey J. Tosoian, Zaid Haddad, Mandeep Takhar, S. Laura Chang, Daniel E. Spratt, Firas Abdollah, Robert B. Jenkins, Eric A. Klein, Paul L. Nguyen, Adam P. Dicker, Robert B. Den, Elai Davicioni, Felix Y. Feng, Tamara L. Lotan, Edward M. Schaeffer
Journal: Clinical Cancer Research
Series: Author Choice
Clin Cancer Res (2018) 24 (16): 3908–3916.
https://doi.org/10.1158/1078-0432.CCR-17-2745
Published: 14 August 2018
View article titled, Development and Validation of a Prostate Cancer Genomic Signature that Predicts Early ADT Treatment Response Following Radical Prostatectomy
Open the PDF for Development and Validation of a Prostate Cancer Genomic Signature that Predicts Early ADT Treatment Response Following Radical Prostatectomy in another window
Includes: Supplementary data
Journal Articles

Maternal Embryonic Leucine Zipper Kinase (MELK) as a Novel Mediator and Biomarker of Radioresistance in Human Breast Cancer

Corey Speers, Shuang G. Zhao, Vishal Kothari, Alyssa Santola, Meilan Liu, Kari Wilder-Romans, Joseph Evans, Nidhi Batra, Harry Bartelink, Daniel F. Hayes, Theodore S. Lawrence, Powel H. Brown, Lori J. Pierce, Felix Y. Feng
Journal: Clinical Cancer Research
Series: Author Choice
Clin Cancer Res (2016) 22 (23): 5864–5875.
https://doi.org/10.1158/1078-0432.CCR-15-2711
Published: 30 November 2016
View article titled, Maternal Embryonic Leucine Zipper Kinase (MELK) as a Novel Mediator and Biomarker of Radioresistance in Human Breast Cancer
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Includes: Supplementary data
Journal Articles

The Landscape of Prognostic Outlier Genes in High-Risk Prostate Cancer

Shuang G. Zhao, Joseph R. Evans, Vishal Kothari, Grace Sun, Ashley Larm, Victor Mondine, Edward M. Schaeffer, Ashley E. Ross, Eric A. Klein, Robert B. Den, Adam P. Dicker, R. Jeffrey Karnes, Nicholas Erho, Paul L. Nguyen, Elai Davicioni, Felix Y. Feng
Journal: Clinical Cancer Research
Clin Cancer Res (2016) 22 (7): 1777–1786.
https://doi.org/10.1158/1078-0432.CCR-15-1250
Published: 31 March 2016
View article titled, The Landscape of Prognostic Outlier Genes in High-Risk Prostate Cancer
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Includes: Supplementary data