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Shiro Akinaga
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Journal Articles

New Molecular and Biological Mechanism of Antitumor Activities of KW-2478, a Novel Nonansamycin Heat Shock Protein 90 Inhibitor, in Multiple Myeloma Cells

Takayuki Nakashima, Toshihiko Ishii, Hisashi Tagaya, Toshihiro Seike, Hiroshi Nakagawa, Yutaka Kanda, Shiro Akinaga, Shiro Soga, Yukimasa Shiotsu
Journal: Clinical Cancer Research
Clin Cancer Res (2010) 16 (10): 2792–2802.
https://doi.org/10.1158/1078-0432.CCR-09-3112
Published: 13 May 2010
View article titled, New Molecular and Biological Mechanism of Antitumor Activities of KW-2478, a Novel Nonansamycin Heat Shock Protein 90 Inhibitor, in Multiple Myeloma Cells
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Includes: Supplementary data
Journal Articles

Defucosylated Humanized Anti-CCR4 Monoclonal Antibody KW-0761 as a Novel Immunotherapeutic Agent for Adult T-cell Leukemia/Lymphoma

Toshihiko Ishii, Takashi Ishida, Atae Utsunomiya, Atsushi Inagaki, Hiroki Yano, Hirokazu Komatsu, Shinsuke Iida, Kazunori Imada, Takashi Uchiyama, Shiro Akinaga, Kenya Shitara, Ryuzo Ueda
Journal: Clinical Cancer Research
Clin Cancer Res (2010) 16 (5): 1520–1531.
https://doi.org/10.1158/1078-0432.CCR-09-2697
Published: 28 February 2010
View article titled, Defucosylated Humanized Anti-CCR4 Monoclonal Antibody KW-0761 as a Novel Immunotherapeutic Agent for Adult T-cell Leukemia/Lymphoma
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Journal Articles

A Novel FLT3 Inhibitor FI-700 Selectively Suppresses the Growth of Leukemia Cells with FLT3 Mutations

Hitoshi Kiyoi, Yukimasa Shiotsu, Kazutaka Ozeki, Satomi Yamaji, Hiroshi Kosugi, Hiroshi Umehara, Makiko Shimizu, Hitoshi Arai, Kenichi Ishii, Shiro Akinaga, Tomoki Naoe
Journal: Clinical Cancer Research
Clin Cancer Res (2007) 13 (15): 4575–4582.
https://doi.org/10.1158/1078-0432.CCR-07-0225
Published: 01 August 2007
View article titled, A Novel FLT3 Inhibitor FI-700 Selectively Suppresses the Growth of Leukemia Cells with FLT3 Mutations
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Journal Articles

A Neutralizing Anti–Fibroblast Growth Factor 8 Monoclonal Antibody Shows Potent Antitumor Activity against Androgen-Dependent Mouse Mammary Tumors In vivo

Naoki Shimada, Toshihiko Ishii, Teruyoshi Imada, Katsumi Takaba, Yuka Sasaki, Kumiko Maruyama-Takahashi, Yoshimi Maekawa-Tokuda, Hideaki Kusaka, Shiro Akinaga, Akira Tanaka, Kenya Shitara
Journal: Clinical Cancer Research
Clin Cancer Res (2005) 11 (10): 3897–3904.
https://doi.org/10.1158/1078-0432.CCR-04-2358
Published: 16 May 2005
View article titled, A Neutralizing Anti–Fibroblast Growth Factor 8 Monoclonal Antibody Shows Potent Antitumor Activity against Androgen-Dependent Mouse Mammary Tumors <em>In vivo</em>
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Journal Articles

The CC Chemokine Receptor 4 as a Novel Specific Molecular Target for Immunotherapy in Adult T-Cell Leukemia/Lymphoma

Takashi Ishida, Shinsuke Iida, Yoshiki Akatsuka, Toshihiko Ishii, Mikinori Miyazaki, Hirokazu Komatsu, Hiroshi Inagaki, Noriko Okada, Teizo Fujita, Kenya Shitara, Shiro Akinaga, Toshitada Takahashi, Atae Utsunomiya, Ryuzo Ueda
Journal: Clinical Cancer Research
Clin Cancer Res (2004) 10 (22): 7529–7539.
https://doi.org/10.1158/1078-0432.CCR-04-0983
Published: 29 November 2004
View article titled, The CC Chemokine Receptor 4 as a Novel Specific Molecular Target for Immunotherapy in Adult T-Cell Leukemia/Lymphoma
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Journal Articles

Destabilization of Steroid Receptors by Heat Shock Protein 90-binding Drugs: A Ligand-independent Approach to Hormonal Therapy of Breast Cancer

Rochelle Bagatell, Omar Khan, Gillian Paine-Murrieta, Charles W. Taylor, Shiro Akinaga, Luke Whitesell
Journal: Clinical Cancer Research
Clin Cancer Res (2001) 7 (7): 2076–2084.
Published: 01 July 2001
View article titled, Destabilization of Steroid Receptors by Heat Shock Protein 90-binding Drugs: <subtitle>A Ligand-independent Approach to Hormonal Therapy of Breast Cancer</subtitle>
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Journal Articles

Induction of a Heat Shock Factor 1-dependent Stress Response Alters the Cytotoxic Activity of Hsp90-binding Agents

Rochelle Bagatell, Gillian D. Paine-Murrieta, Charles W. Taylor, Elizabeth J. Pulcini, Shiro Akinaga, Ivor J. Benjamin, Luke Whitesell
Journal: Clinical Cancer Research
Clin Cancer Res (2000) 6 (8): 3312–3318.
Published: 01 August 2000
View article titled, Induction of a Heat Shock Factor 1-dependent Stress Response Alters the Cytotoxic Activity of Hsp90-binding Agents
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