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Shi-Yong Sun
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Journal Articles

Overcoming Acquired Resistance to AZD9291, A Third-Generation EGFR Inhibitor, through Modulation of MEK/ERK-Dependent Bim and Mcl-1 Degradation

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Puyu Shi, You-Take Oh, Liang Deng, Guojing Zhang, Guoqing Qian, Shuo Zhang, Hui Ren, Grant Wu, Benjamin Legendre, Jr, Emily Anderson, Suresh S. Ramalingam, Taofeek K. Owonikoko, Mingwei Chen, Shi-Yong Sun
Journal: Clinical Cancer Research
Clin Cancer Res (2017) 23 (21): 6567–6579.
https://doi.org/10.1158/1078-0432.CCR-17-1574
Published: 31 October 2017
View articletitled, Overcoming Acquired Resistance to AZD9291, A Third-Generation EGFR Inhibitor, through Modulation of MEK/ERK-Dependent Bim and Mcl-1 Degradation
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Includes: Supplementary data
Journal Articles

A Translational, Pharmacodynamic, and Pharmacokinetic Phase IB Clinical Study of Everolimus in Resectable Non–Small Cell Lung Cancer

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Taofeek K. Owonikoko, Suresh S. Ramalingam, Daniel L. Miller, Seth D. Force, Gabriel L. Sica, Jennifer Mendel, Zhengjia Chen, Andre Rogatko, Mourad Tighiouart, R. Donald Harvey, Sungjin Kim, Nabil F. Saba, Allan Pickens, Madhusmita Behera, Robert W. Fu, Michael R. Rossi, William F. Auffermann, William E. Torres, Rabih Bechara, Xingming Deng, Shi-Yong Sun, Haian Fu, Anthony A. Gal, Fadlo R. Khuri
Journal: Clinical Cancer Research
Clin Cancer Res (2015) 21 (8): 1859–1868.
https://doi.org/10.1158/1078-0432.CCR-14-1998
Published: 14 April 2015
View articletitled, A Translational, Pharmacodynamic, and Pharmacokinetic Phase IB Clinical Study of Everolimus in Resectable Non–Small Cell Lung Cancer
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Includes: Supplementary data
Journal Articles

Activation of COX-2 mediates growth arrest and apoptosis induced by perifosine in human lung cancer cells

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Heath Elrod, Ping Yue, Fadlo Khuri, Shi-Yong Sun
Journal: Clinical Cancer Research
Clin Cancer Res (2007) 13 (19_Supplement): B41.
Published: 15 August 2014
View articletitled, Activation of COX-2 mediates growth arrest and apoptosis induced by perifosine in human lung cancer cells
Journal Articles

Drozitumab, a Human Antibody to Death Receptor 5, Has Potent Antitumor Activity against Rhabdomyosarcoma with the Expression of Caspase-8 Predictive of Response

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Zhigang Kang, Jun-Jie Chen, Yunkai Yu, Bo Li, Shi-Yong Sun, Baolin Zhang, Liang Cao
Journal: Clinical Cancer Research
Clin Cancer Res (2011) 17 (10): 3181–3192.
https://doi.org/10.1158/1078-0432.CCR-10-2874
Published: 15 May 2011
View articletitled, Drozitumab, a Human Antibody to Death Receptor 5, Has Potent Antitumor Activity against Rhabdomyosarcoma with the Expression of Caspase-8 Predictive of Response
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Includes: Supplementary data
Journal Articles

Perifosine Synergistically Enhances TRAIL-Induced Myeloma Cell Apoptosis via Up-Regulation of Death Receptors

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Ebenezer David, Rajni Sinha, Jing Chen, Shi-Yong Sun, Jonathan L. Kaufman, Sagar Lonial
Journal: Clinical Cancer Research
Clin Cancer Res (2008) 14 (16): 5090–5098.
https://doi.org/10.1158/1078-0432.CCR-08-0016
Published: 12 August 2008
View articletitled, Perifosine Synergistically Enhances TRAIL-Induced Myeloma Cell Apoptosis via Up-Regulation of Death Receptors
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Journal Articles

Vitamin C Inactivates the Proteasome Inhibitor PS-341 in Human Cancer Cells

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Wei Zou, Ping Yue, Na Lin, Min He, Zhongmei Zhou, Sagal Lonial, Fadlo R. Khuri, Binghe Wang, Shi-Yong Sun
Journal: Clinical Cancer Research
Clin Cancer Res (2006) 12 (1): 273–280.
https://doi.org/10.1158/1078-0432.CCR-05-0503
Published: 05 January 2006
View articletitled, Vitamin C Inactivates the Proteasome Inhibitor PS-341 in Human Cancer Cells
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Journal Articles

Tumor Growth Inhibition by Simultaneously Blocking Epidermal Growth Factor Receptor and Cyclooxygenase-2 in a Xenograft Model

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Xin Zhang, Zhuo (Georgia) Chen, Mi Sun Choe, Yan Lin, Shi-Yong Sun, H. Samuel Wieand, Hyung Ju C. Shin, Amy Chen, Fadlo R. Khuri, Dong M. Shin
Journal: Clinical Cancer Research
Clin Cancer Res (2005) 11 (17): 6261–6269.
https://doi.org/10.1158/1078-0432.CCR-04-2102
Published: 06 September 2005
View articletitled, Tumor Growth Inhibition by Simultaneously Blocking Epidermal Growth Factor Receptor and Cyclooxygenase-2 in a Xenograft Model
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Journal Articles

Identification of Receptor-selective Retinoids That Are Potent Inhibitors of the Growth of Human Head and Neck Squamous Cell Carcinoma Cells

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Shi-Yong Sun, Ping Yue, Li Mao, Marcia I. Dawson, Braham Shroot, William W. Lamph, Richard A. Heyman, Roshantha A. S. Chandraratna, Koichi Shudo, Waun K. Hong, Reuben Lotan
Journal: Clinical Cancer Research
Clin Cancer Res (2000) 6 (4): 1563–1573.
Published: 01 April 2000
View articletitled, Identification of Receptor-selective Retinoids That Are Potent Inhibitors of the Growth of Human Head and Neck Squamous Cell Carcinoma Cells
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Journal Articles

Differential Responses of Normal, Premalignant, and Malignant Human Bronchial Epithelial Cells to Receptor-selective Retinoids

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Shi-Yong Sun, Jonathan M. Kurie, Ping Yue, Marcia I. Dawson, Braham Shroot, Roshantna A. S. Chandraratna, Waun K. Hong, Reuben Lotan
Journal: Clinical Cancer Research
Clin Cancer Res (1999) 5 (2): 431–437.
Published: 01 February 1999
View articletitled, Differential Responses of Normal, Premalignant, and Malignant Human Bronchial Epithelial Cells to Receptor-selective Retinoids
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