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Sheung-Tat Fan
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Journal Articles

Brain-Derived Neurotrophic Factor Promotes Tumorigenesis via Induction of Neovascularization: Implication in Hepatocellular Carcinoma

Chi-Tat Lam, Zhen-Fan Yang, Chi-Keung Lau, Ka-Ho Tam, Sheung-Tat Fan, Ronnie T.P. Poon
Journal: Clinical Cancer Research
Clin Cancer Res (2011) 17 (10): 3123–3133.
https://doi.org/10.1158/1078-0432.CCR-10-2802
Published: 15 May 2011
View article titled, Brain-Derived Neurotrophic Factor Promotes Tumorigenesis via Induction of Neovascularization: Implication in Hepatocellular Carcinoma
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Includes: Supplementary data
Journal Articles

Suppression of Liver Tumor Growth and Metastasis by Adiponectin in Nude Mice through Inhibition of Tumor Angiogenesis and Downregulation of Rho Kinase/IFN-Inducible Protein 10/Matrix Metalloproteinase 9 Signaling

Kwan Man, Kevin T.P. Ng, Aimin Xu, Qiao Cheng, Chung Mau Lo, Jiang Wei Xiao, Bai Shun Sun, Zophia X.H. Lim, Jerry S. Cheung, Ed X. Wu, Chris K.W. Sun, Ronnie T.P. Poon, Sheung Tat Fan
Journal: Clinical Cancer Research
Clin Cancer Res (2010) 16 (3): 967–977.
https://doi.org/10.1158/1078-0432.CCR-09-1487
Published: 01 February 2010
View article titled, Suppression of Liver Tumor Growth and Metastasis by Adiponectin in Nude Mice through Inhibition of Tumor Angiogenesis and Downregulation of Rho Kinase/IFN-Inducible Protein 10/Matrix Metalloproteinase 9 Signaling
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Journal Articles

An Akt/Hypoxia-Inducible Factor-1α/Platelet-Derived Growth Factor-BB Autocrine Loop Mediates Hypoxia-Induced Chemoresistance in Liver Cancer Cells and Tumorigenic Hepatic Progenitor Cells

Chi Keung Lau, Zhen Fan Yang, David W. Ho, Michael N. Ng, George C.T. Yeoh, Ronnie T.P. Poon, Sheung Tat Fan
Journal: Clinical Cancer Research
Clin Cancer Res (2009) 15 (10): 3462–3471.
https://doi.org/10.1158/1078-0432.CCR-08-2127
Published: 18 May 2009
View article titled, An Akt/Hypoxia-Inducible Factor-1α/Platelet-Derived Growth Factor-BB Autocrine Loop Mediates Hypoxia-Induced Chemoresistance in Liver Cancer Cells and Tumorigenic Hepatic Progenitor Cells
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Includes: Supplementary data
Journal Articles

Regulation of Angiogenesis by Id-1 through Hypoxia-Inducible Factor-1α–Mediated Vascular Endothelial Growth Factor Up-regulation in Hepatocellular Carcinoma

Terence K. Lee, Ronnie T.P. Poon, Anthony P. Yuen, Ming Tat Ling, Xiang Hong Wang, Yong Chuan Wong, Xin Yuan Guan, Kwan Man, Zao You Tang, Sheung Tat Fan
Journal: Clinical Cancer Research
Clin Cancer Res (2006) 12 (23): 6910–6919.
https://doi.org/10.1158/1078-0432.CCR-06-0489
Published: 04 December 2006
View article titled, Regulation of Angiogenesis by Id-1 through Hypoxia-Inducible Factor-1α–Mediated Vascular Endothelial Growth Factor Up-regulation in Hepatocellular Carcinoma
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Journal Articles

Twist Overexpression Correlates with Hepatocellular Carcinoma Metastasis through Induction of Epithelial-Mesenchymal Transition

Terence K. Lee, Ronnie T.P. Poon, Anthony P. Yuen, Ming Tat Ling, Wei Kei Kwok, Xiang Hong Wang, Yong Chuan Wong, Xin Yuan Guan, Kwan Man, King Lok Chau, Sheung Tat Fan
Journal: Clinical Cancer Research
Clin Cancer Res (2006) 12 (18): 5369–5376.
https://doi.org/10.1158/1078-0432.CCR-05-2722
Published: 25 September 2006
View article titled, Twist Overexpression Correlates with Hepatocellular Carcinoma Metastasis through Induction of Epithelial-Mesenchymal Transition
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Journal Articles

Liver Intestine-Cadherin (CDH17) Haplotype Is Associated with Increased Risk of Hepatocellular Carcinoma

Xiao Qi Wang, John M. Luk, Mercè Garcia-Barcelo, Xiaoping Miao, Pauline P. Leung, David W. Ho, Siu Tim Cheung, Brian Y. Lam, Cindy K. Cheung, Ashley S. Wong, Silvana S. Lau, Man Ting So, Wan Ching Yu, Qi Cai, Karen S. Liu, Chee Kin Hui, George K. Lau, Ronnie T.P. Poon, John Wong, Sheung Tat Fan
Journal: Clinical Cancer Research
Clin Cancer Res (2006) 12 (17): 5248–5252.
https://doi.org/10.1158/1078-0432.CCR-06-0558
Published: 01 September 2006
View article titled, Liver Intestine-Cadherin (<em>CDH17</em>) Haplotype Is Associated with Increased Risk of Hepatocellular Carcinoma
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Journal Articles

Rac Activation Is Associated with Hepatocellular Carcinoma Metastasis by Up-regulation of Vascular Endothelial Growth Factor Expression

Terence K. Lee, Ronnie T.P. Poon, Anthony P. Yuen, Kwan Man, Zhen Fan Yang, Xin Yuan Guan, Sheung Tat Fan
Journal: Clinical Cancer Research
Clin Cancer Res (2006) 12 (17): 5082–5089.
https://doi.org/10.1158/1078-0432.CCR-05-2794
Published: 01 September 2006
View article titled, Rac Activation Is Associated with Hepatocellular Carcinoma Metastasis by Up-regulation of Vascular Endothelial Growth Factor Expression
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Journal Articles

FTY720: A Promising Agent for Treatment of Metastatic Hepatocellular Carcinoma

Terence K. Lee, Kwan Man, Joanna W. Ho, Xiang Hong Wang, Ronnie T.P. Poon, Yang Xu, Kevin T. Ng, Alan C. Chu, Chris K. Sun, Irene O. Ng, Hui Chuan Sun, Zao You Tang, Ray Xu, Sheung Tat Fan
Journal: Clinical Cancer Research
Clin Cancer Res (2005) 11 (23): 8458–8466.
https://doi.org/10.1158/1078-0432.CCR-05-0447
Published: 01 December 2005
View article titled, FTY720: A Promising Agent for Treatment of Metastatic Hepatocellular Carcinoma
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Journal Articles

Alternative mRNA Splicing of Liver Intestine-Cadherin in Hepatocellular Carcinoma

Xiao Qi Wang, John M. Luk, Pauline P. Leung, Bonnie W. Wong, Eric J. Stanbridge, Sheung Tat Fan
Journal: Clinical Cancer Research
Clin Cancer Res (2005) 11 (2): 483–489.
https://doi.org/10.1158/1078-0432.483.11.2
Published: 08 February 2005
View article titled, Alternative mRNA Splicing of Liver Intestine-Cadherin in Hepatocellular Carcinoma
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Journal Articles

Claudin-10 Expression Level is Associated with Recurrence of Primary Hepatocellular Carcinoma

Siu Tim Cheung, Ka Ling Leung, Ying Chi Ip, Xin Chen, Daniel Y. Fong, Irene O. Ng, Sheung Tat Fan, Samuel So
Journal: Clinical Cancer Research
Clin Cancer Res (2005) 11 (2): 551–556.
https://doi.org/10.1158/1078-0432.551.11.2
Published: 08 February 2005
View article titled, Claudin-10 Expression Level is Associated with Recurrence of Primary Hepatocellular Carcinoma
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Includes: Supplementary data
Journal Articles

Granulin–Epithelin Precursor Overexpression Promotes Growth and Invasion of Hepatocellular Carcinoma

Siu Tim Cheung, San Yu Wong, Ka Ling Leung, Xin Chen, Samuel So, Irene O. Ng, Sheung Tat Fan
Journal: Clinical Cancer Research
Clin Cancer Res (2004) 10 (22): 7629–7636.
https://doi.org/10.1158/1078-0432.CCR-04-0960
Published: 29 November 2004
View article titled, Granulin–Epithelin Precursor Overexpression Promotes Growth and Invasion of Hepatocellular Carcinoma
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Journal Articles

Evaluation of Nuclear Factor-κB, Urokinase-Type Plasminogen Activator, and HBx and Their Clinicopathological Significance in Hepatocellular Carcinoma

Chun-Fung Chan, Tai-On Yau, Dong-Yan Jin, Chun-Ming Wong, Sheung-Tat Fan, Irene Oi-Lin Ng
Journal: Clinical Cancer Research
Clin Cancer Res (2004) 10 (12): 4140–4149.
https://doi.org/10.1158/1078-0432.CCR-03-0574
Published: 24 June 2004
View article titled, Evaluation of Nuclear Factor-κB, Urokinase-Type Plasminogen Activator, and HBx and Their Clinicopathological Significance in Hepatocellular Carcinoma
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Journal Articles

Clinical Significance of Thrombospondin 1 Expression in Hepatocellular Carcinoma

Ronnie T. Poon, Ka Kit Chung, Siu Tim Cheung, Cecilia P. Lau, See Wai Tong, Ka Ling Leung, Wan Ching Yu, George P. Tuszynski, Sheung Tat Fan
Journal: Clinical Cancer Research
Clin Cancer Res (2004) 10 (12): 4150–4157.
https://doi.org/10.1158/1078-0432.CCR-03-0435
Published: 24 June 2004
View article titled, Clinical Significance of Thrombospondin 1 Expression in Hepatocellular Carcinoma
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Journal Articles

Interleukin-8 Serum Levels in Patients with Hepatocellular Carcinoma: Correlations with Clinicopathological Features and Prognosis

Yi Ren, Ronnie Tung-Ping Poon, Hong-Teng Tsui, Wen-Hong Chen, Zhi Li, Cecilia Lau, Wun-Ching Yu, Sheung-Tat Fan
Journal: Clinical Cancer Research
Clin Cancer Res (2003) 9 (16): 5996–6001.
Published: 15 December 2003
View article titled, Interleukin-8 Serum Levels in Patients with Hepatocellular Carcinoma: <subtitle>Correlations with Clinicopathological Features and Prognosis</subtitle>
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Journal Articles

Tissue Factor Expression Correlates with Tumor Angiogenesis and Invasiveness in Human Hepatocellular Carcinoma

Ronnie Tung-Ping Poon, Cecilia Pik-Yuk Lau, Joanna Wen-Ying Ho, Wan-Ching Yu, Sheung-Tat Fan, John Wong
Journal: Clinical Cancer Research
Clin Cancer Res (2003) 9 (14): 5339–5345.
Published: 12 November 2003
View article titled, Tissue Factor Expression Correlates with Tumor Angiogenesis and Invasiveness in Human Hepatocellular Carcinoma
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Journal Articles

Clinicopathological Significance of Loss of Heterozygosity on Chromosome 13q in Hepatocellular Carcinoma

Chun Ming Wong, Joyce Man Fong Lee, Tracy Ching Man Lau, Sheung Tat Fan, Irene O. L. Ng
Journal: Clinical Cancer Research
Clin Cancer Res (2002) 8 (7): 2266–2272.
Published: 01 July 2002
View article titled, Clinicopathological Significance of Loss of Heterozygosity on Chromosome 13q in Hepatocellular Carcinoma
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