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Shailender Bhatia
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Journal Articles

Combination of the STING Agonist MIW815 (ADU-S100) and PD-1 Inhibitor Spartalizumab in Advanced/Metastatic Solid Tumors or Lymphomas: An Open-Label, Multicenter, Phase Ib Study

Funda Meric-Bernstam, Randy F. Sweis, Stefan Kasper, Omid Hamid, Shailender Bhatia, Reinhard Dummer, Agostina Stradella, Georgina V. Long, Anna Spreafico, Toshio Shimizu, Neeltje Steeghs, Jason J. Luke, Sarah M. McWhirter, Thomas Müller, Nitya Nair, Nancy Lewis, Xinhui Chen, Andrew Bean, Lisa Kattenhorn, Marc Pelletier, Shahneen Sandhu
Journal: Clinical Cancer Research
Clin Cancer Res (2023) 29 (1): 110–121.
https://doi.org/10.1158/1078-0432.CCR-22-2235
Published: 04 January 2023
View article titled, Combination of the STING Agonist MIW815 (ADU-S100) and PD-1 Inhibitor Spartalizumab in Advanced/Metastatic Solid Tumors or Lymphomas: An Open-Label, Multicenter, Phase Ib Study
Open the PDF for Combination of the STING Agonist MIW815 (ADU-S100) and PD-1 Inhibitor Spartalizumab in Advanced/Metastatic Solid Tumors or Lymphomas: An Open-Label, Multicenter, Phase Ib Study in another window
Includes: Supplementary data
Journal Articles

Phase II Trial of IL-12 Plasmid Transfection and PD-1 Blockade in Immunologically Quiescent Melanoma

Alain P. Algazi, Christopher G. Twitty, Katy K. Tsai, Mai Le, Robert Pierce, Erica Browning, Reneta Hermiz, David A. Canton, Donna Bannavong, Arielle Oglesby, Murray Francisco, Lawrence Fong, Mikael J. Pittet, Sean P. Arlauckas, Christopher Garris, Lauren P. Levine, Carlos Bifulco, Carmen Ballesteros-Merino, Shailender Bhatia, Sharron Gargosky, Robert H.I. Andtbacka, Bernard A. Fox, Michael D. Rosenblum, Adil I. Daud
Journal: Clinical Cancer Research
Clin Cancer Res (2020) 26 (12): 2827–2837.
https://doi.org/10.1158/1078-0432.CCR-19-2217
Published: 15 June 2020
View article titled, Phase II Trial of IL-12 Plasmid Transfection and PD-1 Blockade in Immunologically Quiescent Melanoma
Open the PDF for Phase II Trial of IL-12 Plasmid Transfection and PD-1 Blockade in Immunologically Quiescent Melanoma in another window
Includes: Supplementary data
Journal Articles

Intratumoral Delivery of Plasmid IL12 Via Electroporation Leads to Regression of Injected and Noninjected Tumors in Merkel Cell Carcinoma

Shailender Bhatia, Natalie V. Longino, Natalie J. Miller, Rima Kulikauskas, Jayasri G. Iyer, Dafina Ibrani, Astrid Blom, David R. Byrd, Upendra Parvathaneni, Christopher G. Twitty, Jean S. Campbell, Mai H. Le, Sharron Gargosky, Robert H. Pierce, Richard Heller, Adil I. Daud, Paul Nghiem
Journal: Clinical Cancer Research
Series: Author Choice
Clin Cancer Res (2020) 26 (3): 598–607.
https://doi.org/10.1158/1078-0432.CCR-19-0972
Published: 03 February 2020
View article titled, Intratumoral Delivery of Plasmid IL12 Via Electroporation Leads to Regression of Injected and Noninjected Tumors in Merkel Cell Carcinoma
Open the PDF for Intratumoral Delivery of Plasmid IL12 Via Electroporation Leads to Regression of Injected and Noninjected Tumors in Merkel Cell Carcinoma in another window
Includes: Supplementary data
Journal Articles

Intratumoral G100, a TLR4 Agonist, Induces Antitumor Immune Responses and Tumor Regression in Patients with Merkel Cell Carcinoma

Shailender Bhatia, Natalie J. Miller, Hailing Lu, Natalie V. Longino, Dafina Ibrani, Michi M. Shinohara, David R. Byrd, Upendra Parvathaneni, Rima Kulikauskas, Jan ter Meulen, Frank J. Hsu, David M. Koelle, Paul Nghiem
Journal: Clinical Cancer Research
Series: Author Choice
Clin Cancer Res (2019) 25 (4): 1185–1195.
https://doi.org/10.1158/1078-0432.CCR-18-0469
Published: 15 February 2019
View article titled, Intratumoral G100, a TLR4 Agonist, Induces Antitumor Immune Responses and Tumor Regression in Patients with Merkel Cell Carcinoma
Open the PDF for Intratumoral G100, a TLR4 Agonist, Induces Antitumor Immune Responses and Tumor Regression in Patients with Merkel Cell Carcinoma in another window
Includes: Supplementary data
Journal Articles

Phase I Study of Single-Agent Utomilumab (PF-05082566), a 4-1BB/CD137 Agonist, in Patients with Advanced Cancer

Neil H. Segal, Aiwu R. He, Toshihiko Doi, Ronald Levy, Shailender Bhatia, Michael J. Pishvaian, Rossano Cesari, Ying Chen, Craig B. Davis, Bo Huang, Aron D. Thall, Ajay K. Gopal
Journal: Clinical Cancer Research
Series: Author Choice
Clin Cancer Res (2018) 24 (8): 1816–1823.
https://doi.org/10.1158/1078-0432.CCR-17-1922
Published: 12 April 2018
View article titled, Phase I Study of Single-Agent Utomilumab (PF-05082566), a 4-1BB/CD137 Agonist, in Patients with Advanced Cancer
Open the PDF for Phase I Study of Single-Agent Utomilumab (PF-05082566), a 4-1BB/CD137 Agonist, in Patients with Advanced Cancer in another window
Includes: Supplementary data
Journal Articles

Pembrolizumab Plus Pegylated Interferon alfa-2b or Ipilimumab for Advanced Melanoma or Renal Cell Carcinoma: Dose-Finding Results from the Phase Ib KEYNOTE-029 Study

Michael B. Atkins, F. Stephen Hodi, John A. Thompson, David F. McDermott, Wen-Jen Hwu, Donald P. Lawrence, Nancy A. Dawson, Deborah J. Wong, Shailender Bhatia, Marihella James, Lokesh Jain, Seth Robey, Xinxin Shu, Blanca Homet Moreno, Rodolfo F. Perini, Toni K. Choueiri, Antoni Ribas
Journal: Clinical Cancer Research
Clin Cancer Res (2018) 24 (8): 1805–1815.
https://doi.org/10.1158/1078-0432.CCR-17-3436
Published: 12 April 2018
View article titled, Pembrolizumab Plus Pegylated Interferon alfa-2b or Ipilimumab for Advanced Melanoma or Renal Cell Carcinoma: Dose-Finding Results from the Phase Ib KEYNOTE-029 Study
Open the PDF for Pembrolizumab Plus Pegylated Interferon alfa-2b or Ipilimumab for Advanced Melanoma or Renal Cell Carcinoma: Dose-Finding Results from the Phase Ib KEYNOTE-029 Study in another window
Includes: Supplementary data
Journal Articles

A Phase I/II Trial of BNC105P with Everolimus in Metastatic Renal Cell Carcinoma

Sumanta Pal, Arun Azad, Shailender Bhatia, Harry Drabkin, Brian Costello, John Sarantopoulos, Ravindran Kanesvaran, Richard Lauer, Alexander Starodub, Ralph Hauke, Christopher J. Sweeney, Noah M. Hahn, Guru Sonpavde, Stephen Richey, Timothy Breen, Gabriel Kremmidiotis, Annabell Leske, Elizabeth Doolin, David C. Bibby, Jeremy Simpson, Jose Iglesias, Thomas Hutson
Journal: Clinical Cancer Research
Clin Cancer Res (2015) 21 (15): 3420–3427.
https://doi.org/10.1158/1078-0432.CCR-14-3370
Published: 02 August 2015
View article titled, A Phase I/II Trial of BNC105P with Everolimus in Metastatic Renal Cell Carcinoma
Open the PDF for A Phase I/II Trial of BNC105P with Everolimus in Metastatic Renal Cell Carcinoma in another window
Includes: Supplementary data