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Setsuo Hirohashi
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Journal Articles

Combined Functional Genome Survey of Therapeutic Targets for Hepatocellular Carcinoma

Reiko Satow, Miki Shitashige, Yae Kanai, Fumitaka Takeshita, Hidenori Ojima, Takafumi Jigami, Kazufumi Honda, Tomoo Kosuge, Takahiro Ochiya, Setsuo Hirohashi, Tesshi Yamada
Journal: Clinical Cancer Research
Clin Cancer Res (2010) 16 (9): 2518–2528.
https://doi.org/10.1158/1078-0432.CCR-09-2214
Published: 28 April 2010
View articletitled, Combined Functional Genome Survey of Therapeutic Targets for Hepatocellular Carcinoma
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Includes: Supplementary data
Journal Articles

Nucleophosmin as a Candidate Prognostic Biomarker of Ewing's Sarcoma Revealed by Proteomics

Kazutaka Kikuta, Naobumi Tochigi, Tadakazu Shimoda, Hiroki Yabe, Hideo Morioka, Yoshiaki Toyama, Ako Hosono, Yasuo Beppu, Akira Kawai, Setsuo Hirohashi, Tadashi Kondo
Journal: Clinical Cancer Research
Clin Cancer Res (2009) 15 (8): 2885–2894.
https://doi.org/10.1158/1078-0432.CCR-08-1913
Published: 15 April 2009
View articletitled, Nucleophosmin as a Candidate Prognostic Biomarker of Ewing's Sarcoma Revealed by Proteomics
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Journal Articles

Expression and Gene Amplification of Actinin-4 in Invasive Ductal Carcinoma of the Pancreas

Satoru Kikuchi, Kazufumi Honda, Hitoshi Tsuda, Nobuyoshi Hiraoka, Issei Imoto, Tomoo Kosuge, Tomoko Umaki, Kaoru Onozato, Miki Shitashige, Umio Yamaguchi, Masaya Ono, Akihiko Tsuchida, Tatsuya Aoki, Johji Inazawa, Setsuo Hirohashi, Tesshi Yamada
Journal: Clinical Cancer Research
Clin Cancer Res (2008) 14 (17): 5348–5356.
https://doi.org/10.1158/1078-0432.CCR-08-0075
Published: 02 September 2008
View articletitled, Expression and Gene Amplification of Actinin-4 in Invasive Ductal Carcinoma of the Pancreas
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Includes: Supplementary data
Journal Articles

Genetic Clustering of Clear Cell Renal Cell Carcinoma Based on Array-Comparative Genomic Hybridization: Its Association with DNA Methylation Alteration and Patient Outcome

Eri Arai, Saori Ushijima, Hitoshi Tsuda, Hiroyuki Fujimoto, Fumie Hosoda, Tatsuhiro Shibata, Tadashi Kondo, Issei Imoto, Johji Inazawa, Setsuo Hirohashi, Yae Kanai
Journal: Clinical Cancer Research
Clin Cancer Res (2008) 14 (17): 5531–5539.
https://doi.org/10.1158/1078-0432.CCR-08-0443
Published: 02 September 2008
View articletitled, Genetic Clustering of Clear Cell Renal Cell Carcinoma Based on Array-Comparative Genomic Hybridization: Its Association with DNA Methylation Alteration and Patient Outcome
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Journal Articles

Pfetin as a Prognostic Biomarker of Gastrointestinal Stromal Tumors Revealed by Proteomics

Yoshiyuki Suehara, Tadashi Kondo, Kunihiko Seki, Tatsuhiro Shibata, Kiyonaga Fujii, Masahiro Gotoh, Tadashi Hasegawa, Yasuhiro Shimada, Mitsuru Sasako, Tadakazu Shimoda, Hisashi Kurosawa, Yasuo Beppu, Akira Kawai, Setsuo Hirohashi
Journal: Clinical Cancer Research
Clin Cancer Res (2008) 14 (6): 1707–1717.
https://doi.org/10.1158/1078-0432.CCR-07-1478
Published: 17 March 2008
View articletitled, Pfetin as a Prognostic Biomarker of Gastrointestinal Stromal Tumors Revealed by Proteomics
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Journal Articles

Proteomic Signature Corresponding to the Response to Gefitinib (Iressa, ZD1839), an Epidermal Growth Factor Receptor Tyrosine Kinase Inhibitor in Lung Adenocarcinoma

Tetsuya Okano, Tadashi Kondo, Kiyonaga Fujii, Toshihide Nishimura, Toshimi Takano, Yuichiro Ohe, Koji Tsuta, Yoshihiro Matsuno, Akihiko Gemma, Harbumi Kato, Shoji Kudoh, Setsuo Hirohashi
Journal: Clinical Cancer Research
Clin Cancer Res (2007) 13 (3): 799–805.
https://doi.org/10.1158/1078-0432.CCR-06-1654
Published: 08 February 2007
View articletitled, Proteomic Signature Corresponding to the Response to Gefitinib (Iressa, ZD1839), an Epidermal Growth Factor Receptor Tyrosine Kinase Inhibitor in Lung Adenocarcinoma
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Includes: Supplementary data
Journal Articles

FOXP3+ Regulatory T Cells Affect the Development and Progression of Hepatocarcinogenesis

Noritoshi Kobayashi, Nobuyoshi Hiraoka, Wataru Yamagami, Hidenori Ojima, Yae Kanai, Tomoo Kosuge, Atsushi Nakajima, Setsuo Hirohashi
Journal: Clinical Cancer Research
Clin Cancer Res (2007) 13 (3): 902–911.
https://doi.org/10.1158/1078-0432.CCR-06-2363
Published: 08 February 2007
View articletitled, FOXP3+ Regulatory T Cells Affect the Development and Progression of Hepatocarcinogenesis
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Journal Articles

Prevalence of FOXP3+ Regulatory T Cells Increases During the Progression of Pancreatic Ductal Adenocarcinoma and Its Premalignant Lesions

Nobuyoshi Hiraoka, Kaoru Onozato, Tomoo Kosuge, Setsuo Hirohashi
Journal: Clinical Cancer Research
Clin Cancer Res (2006) 12 (18): 5423–5434.
https://doi.org/10.1158/1078-0432.CCR-06-0369
Published: 25 September 2006
View articletitled, Prevalence of FOXP3+ Regulatory T Cells Increases During the Progression of Pancreatic Ductal Adenocarcinoma and Its Premalignant Lesions
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Journal Articles

Overexpression of Cyclase-Associated Protein 2 in Multistage Hepatocarcinogenesis

Rie Shibata, Taisuke Mori, Wenlin Du, Makoto Chuma, Masahiro Gotoh, Motohide Shimazu, Masakazu Ueda, Setsuo Hirohashi, Michiie Sakamoto
Journal: Clinical Cancer Research
Clin Cancer Res (2006) 12 (18): 5363–5368.
https://doi.org/10.1158/1078-0432.CCR-05-2245
Published: 25 September 2006
View articletitled, Overexpression of Cyclase-Associated Protein 2 in Multistage Hepatocarcinogenesis
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Journal Articles

Establishment of Perineural Invasion Models and Analysis of Gene Expression Revealed an Invariant Chain (CD74) as a Possible Molecule Involved in Perineural Invasion in Pancreatic Cancer

Norimasa Koide, Taketo Yamada, Rie Shibata, Taisuke Mori, Mariko Fukuma, Ken Yamazaki, Koichi Aiura, Motohide Shimazu, Setsuo Hirohashi, Yuji Nimura, Michiie Sakamoto
Journal: Clinical Cancer Research
Clin Cancer Res (2006) 12 (8): 2419–2426.
https://doi.org/10.1158/1078-0432.CCR-05-1852
Published: 25 April 2006
View articletitled, Establishment of Perineural Invasion Models and Analysis of Gene Expression Revealed an Invariant Chain (CD74) as a Possible Molecule Involved in Perineural Invasion in Pancreatic Cancer
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Journal Articles

Possible Prediction of Chemoradiosensitivity of Esophageal Cancer by Serum Protein Profiling

Yasuharu Hayashida, Kazufumi Honda, Yoshiaki Osaka, Tomohiko Hara, Tomoko Umaki, Akihiko Tsuchida, Tatsuya Aoki, Setsuo Hirohashi, Tesshi Yamada
Journal: Clinical Cancer Research
Clin Cancer Res (2005) 11 (22): 8042–8047.
https://doi.org/10.1158/1078-0432.CCR-05-0656
Published: 18 November 2005
View articletitled, Possible Prediction of Chemoradiosensitivity of Esophageal Cancer by Serum Protein Profiling
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Includes: Supplementary data
Journal Articles

Genetic Classification of Lung Adenocarcinoma Based on Array-Based Comparative Genomic Hybridization Analysis: Its Association with Clinicopathologic Features

Tatsuhiro Shibata, Satomi Uryu, Akiko Kokubu, Fumie Hosoda, Misao Ohki, Tokuki Sakiyama, Yoshihiro Matsuno, Ryosuke Tsuchiya, Yae Kanai, Tadashi Kondo, Issei Imoto, Johji Inazawa, Setsuo Hirohashi
Journal: Clinical Cancer Research
Clin Cancer Res (2005) 11 (17): 6177–6185.
https://doi.org/10.1158/1078-0432.CCR-05-0293
Published: 06 September 2005
View articletitled, Genetic Classification of Lung Adenocarcinoma Based on Array-Based Comparative Genomic Hybridization Analysis: Its Association with Clinicopathologic Features
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Journal Articles

Prognostic Significance of Tissue Factor in Pancreatic Ductal Adenocarcinoma

Nobuhiro Nitori, Yoshinori Ino, Yukihiro Nakanishi, Tesshi Yamada, Kazufumi Honda, Kazuyoshi Yanagihara, Tomoo Kosuge, Yae Kanai, Masaki Kitajima, Setsuo Hirohashi
Journal: Clinical Cancer Research
Clin Cancer Res (2005) 11 (7): 2531–2539.
https://doi.org/10.1158/1078-0432.CCR-04-0866
Published: 06 April 2005
View articletitled, Prognostic Significance of Tissue Factor in Pancreatic Ductal Adenocarcinoma
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Journal Articles

Clinical Significance of Dysadherin Expression in Gastric Cancer Patients

Yutaka Shimada, Seiji Yamasaki, Yosuke Hashimoto, Tetsuo Ito, Jun-ichiro Kawamura, Toshiya Soma, Yoshinori Ino, Yukihiro Nakanishi, Michiie Sakamoto, Setsuo Hirohashi, Masayuki Imamura
Journal: Clinical Cancer Research
Clin Cancer Res (2004) 10 (8): 2818–2823.
https://doi.org/10.1158/1078-0432.CCR-0633-03
Published: 20 April 2004
View articletitled, Clinical Significance of Dysadherin Expression in Gastric Cancer Patients
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Journal Articles

Clinicopathological Significance of Galectin-3 Expression in Ductal Adenocarcinoma of the Pancreas

Takeshi Shimamura, Michiie Sakamoto, Yoshinori Ino, Kazuaki Shimada, Tomoo Kosuge, Yasuto Sato, Katsuaki Tanaka, Hisahiko Sekihara, Setsuo Hirohashi
Journal: Clinical Cancer Research
Clin Cancer Res (2002) 8 (8): 2570–2575.
Published: 01 August 2002
View articletitled, Clinicopathological Significance of Galectin-3 Expression in Ductal Adenocarcinoma of the Pancreas
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Journal Articles

Src Family Kinase Inhibitor PP2 Restores the E-Cadherin/Catenin Cell Adhesion System in Human Cancer Cells and Reduces Cancer Metastasis

Jeong-Seok Nam, Yoshinori Ino, Michiie Sakamoto, Setsuo Hirohashi
Journal: Clinical Cancer Research
Clin Cancer Res (2002) 8 (7): 2430–2436.
Published: 01 July 2002
View articletitled, Src Family Kinase Inhibitor PP2 Restores the E-Cadherin/Catenin Cell Adhesion System in Human Cancer Cells and Reduces Cancer Metastasis
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Journal Articles

Cloning and Characterization of a Novel Gene, DRH1, Down-Regulated in Advanced Human Hepatocellular Carcinoma

Yoshiya Yamamoto, Michiie Sakamoto, Gen Fujii, Kengo Kanetaka, Masahiro Asaka, Setsuo Hirohashi
Journal: Clinical Cancer Research
Clin Cancer Res (2001) 7 (2): 297–303.
Published: 01 February 2001
View articletitled, Cloning and Characterization of a Novel Gene, DRH1, Down-Regulated in Advanced Human Hepatocellular Carcinoma
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Journal Articles

Expression of Vascular Endothelial Growth Factors A, B, C, and D and Their Relationships to Lymph Node Status in Lung Adenocarcinoma

Toshiro Niki, Sanae Iba, Masahide Tokunou, Tesshi Yamada, Yoshihiro Matsuno, Setsuo Hirohashi
Journal: Clinical Cancer Research
Clin Cancer Res (2000) 6 (6): 2431–2439.
Published: 01 June 2000
View articletitled, Expression of Vascular Endothelial Growth Factors A, B, C, and D and Their Relationships to Lymph Node Status in Lung Adenocarcinoma
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Journal Articles

Prognostic Significance of Allelic Imbalances on Chromosome 9p in Stage I Non-Small Cell Lung Carcinoma

Yoshio Tomizawa, Jun-ichi Adachi, Takashi Kohno, Kunihiro Hamada, Ryusei Saito, Masayuki Noguchi, Yoshihiro Matsuno, Setsuo Hirohashi, Naohito Yamaguchi, Jun Yokota
Journal: Clinical Cancer Research
Clin Cancer Res (1999) 5 (5): 1139–1146.
Published: 01 May 1999
View articletitled, Prognostic Significance of Allelic Imbalances on Chromosome 9p in Stage I Non-Small Cell Lung Carcinoma
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