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Sabine C. Linn
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Journal Articles

Differential Survival and Therapy Benefit of Patients with Breast Cancer Are Characterized by Distinct Epithelial and Immune Cell Microenvironments

Lennart Kester, Danielle Seinstra, Annelot G.J. van Rossum, Claire Vennin, Marlous Hoogstraat, Daphne van der Velden, Mark Opdam, Erik van Werkhoven, Kerstin Hahn, Iris Nederlof, Ester H. Lips, Ingrid A.M. Mandjes, A. Elise van Leeuwen-Stok, Sander Canisius, Harm van Tinteren, Alex L.T. Imholz, Johanneke E.A. Portielje, Monique E.M.M. Bos, Sandra D. Bakker, Emiel J. Rutgers, Hugo M. Horlings, Jelle Wesseling, Emile E. Voest, Lodewyk F.A. Wessels, Marleen Kok, Hendrika M. Oosterkamp, Alexander van Oudenaarden, Sabine C. Linn, Jacco van Rheenen
Journal: Clinical Cancer Research
Clin Cancer Res (2022) 28 (5): 960–971.
https://doi.org/10.1158/1078-0432.CCR-21-1442
Published: 01 March 2022
View article titled, Differential Survival and Therapy Benefit of Patients with Breast Cancer Are Characterized by Distinct Epithelial and Immune Cell Microenvironments
Open the PDF for Differential Survival and Therapy Benefit of Patients with Breast Cancer Are Characterized by Distinct Epithelial and Immune Cell Microenvironments in another window
Includes: Supplementary data
Journal Articles

Ovarian Cancer–Specific BRCA-like Copy-Number Aberration Classifiers Detect Mutations Associated with Homologous Recombination Deficiency in the AGO-TR1 Trial

Philip C. Schouten, Lisa Richters, Daniel J. Vis, Stefan Kommoss, Ewald van Dijk, Corinna Ernst, Roelof J.C. Kluin, Frederik Marmé, Esther H. Lips, Sandra Schmidt, Esther Scheerman, Katharina Prieske, Carolien H.M. van Deurzen, Alexander Burges, Patricia C. Ewing-Graham, Dimo Dietrich, Agnes Jager, Nikolaus de Gregorio, Jan Hauke, Andreas du Bois, Petra M. Nederlof, Lodewyk F. Wessels, Eric Hahnen, Philipp Harter, Sabine C. Linn, Rita K. Schmutzler
Journal: Clinical Cancer Research
Clin Cancer Res (2021) 27 (23): 6559–6569.
https://doi.org/10.1158/1078-0432.CCR-21-1673
Published: 01 December 2021
View article titled, Ovarian Cancer–Specific <em>BRCA</em>-like Copy-Number Aberration Classifiers Detect Mutations Associated with Homologous Recombination Deficiency in the AGO-TR1 Trial
Open the PDF for Ovarian Cancer–Specific <em>BRCA</em>-like Copy-Number Aberration Classifiers Detect Mutations Associated with Homologous Recombination Deficiency in the AGO-TR1 Trial in another window
Includes: Supplementary data
Journal Articles

POSEIDON Trial Phase 1b Results: Safety, Efficacy and Circulating Tumor DNA Response of the Beta Isoform-Sparing PI3K Inhibitor Taselisib (GDC-0032) Combined with Tamoxifen in Hormone Receptor Positive Metastatic Breast Cancer Patients

Richard D. Baird, Annelot G.J. van Rossum, Mafalda Oliveira, Karin Beelen, Meiling Gao, Mariette Schrier, Ingrid A.M. Mandjes, Javier Garcia-Corbacho, Anne-Laure Vallier, Greig Dougall, Erik van Werkhoven, Constanza Linossi, Sanjeev Kumar, Harm van Tinteren, Maurizio Callari, Emma Beddowes, José-Manuel Perez-Garcia, Hilde Rosing, Else Platte, Petra Nederlof, Margaret Schot, Aurelia de Vries Schultink, René Bernards, Cristina Saura, William Gallagher, Javier Cortès, Carlos Caldas, Sabine C. Linn
Journal: Clinical Cancer Research
Clin Cancer Res (2019) 25 (22): 6598–6605.
https://doi.org/10.1158/1078-0432.CCR-19-0508
Published: 15 November 2019
View article titled, POSEIDON Trial Phase 1b Results: Safety, Efficacy and Circulating Tumor DNA Response of the Beta Isoform-Sparing PI3K Inhibitor Taselisib (GDC-0032) Combined with Tamoxifen in Hormone Receptor Positive Metastatic Breast Cancer Patients
Open the PDF for POSEIDON Trial Phase 1b Results: Safety, Efficacy and Circulating Tumor DNA Response of the Beta Isoform-Sparing PI3K Inhibitor Taselisib (GDC-0032) Combined with Tamoxifen in Hormone Receptor Positive Metastatic Breast Cancer Patients in another window
Includes: Supplementary data
Journal Articles

Breast Cancers with a BRCA1-like DNA Copy Number Profile Recur Less Often Than Expected after High-Dose Alkylating Chemotherapy

Philip C. Schouten, Frederik Marmé, Sebastian Aulmann, Hans-Peter Sinn, Hendrik F. van Essen, Bauke Ylstra, Michael Hauptmann, Andreas Schneeweiss, Sabine C. Linn
Journal: Clinical Cancer Research
Series: Author Choice
Clin Cancer Res (2015) 21 (4): 763–770.
https://doi.org/10.1158/1078-0432.CCR-14-1894
Published: 16 February 2015
View article titled, Breast Cancers with a <em>BRCA1</em>-like DNA Copy Number Profile Recur Less Often Than Expected after High-Dose Alkylating Chemotherapy
Open the PDF for Breast Cancers with a <em>BRCA1</em>-like DNA Copy Number Profile Recur Less Often Than Expected after High-Dose Alkylating Chemotherapy in another window
Includes: Supplementary data
Journal Articles

Microarray-Based Determination of Estrogen Receptor, Progesterone Receptor, and HER2 Receptor Status in Breast Cancer

Paul Roepman, Hugo M. Horlings, Oscar Krijgsman, Marleen Kok, Jolien M. Bueno-de-Mesquita, Richard Bender, Sabine C. Linn, Annuska M. Glas, Marc J. van de Vijver
Journal: Clinical Cancer Research
Clin Cancer Res (2009) 15 (22): 7003–7011.
https://doi.org/10.1158/1078-0432.CCR-09-0449
Published: 11 November 2009
View article titled, Microarray-Based Determination of Estrogen Receptor, Progesterone Receptor, and HER2 Receptor Status in Breast Cancer
Open the PDF for Microarray-Based Determination of Estrogen Receptor, Progesterone Receptor, and HER2 Receptor Status in Breast Cancer in another window