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Journal Articles

High basal level gene expression of thymidine phosphorylase (platelet-derived endothelial cell growth factor) in colorectal tumors is associated with nonresponse to 5-fluorouracil.

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R Metzger, K Danenberg, C G Leichman, D Salonga, E L Schwartz, S Wadler, H J Lenz, S Groshen, L Leichman, P V Danenberg
Journal: Clinical Cancer Research
Clin Cancer Res (1998) 4 (10): 2371–2376.
Published: 01 October 1998
View article titled, High basal level gene expression of thymidine phosphorylase (platelet-derived endothelial cell growth factor) in colorectal tumors is associated with nonresponse to 5-fluorouracil.
Open the PDF for High basal level gene expression of thymidine phosphorylase (platelet-derived endothelial cell growth factor) in colorectal tumors is associated with nonresponse to 5-fluorouracil. in another window
Journal Articles

Cellular but not plasma pharmacokinetics of lometrexol correlate with the occurrence of cumulative hematological toxicity.

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T W Synold, E M Newman, M Carroll, F M Muggia, S Groshen, K Johnson, J H Doroshow
Journal: Clinical Cancer Research
Clin Cancer Res (1998) 4 (10): 2349–2355.
Published: 01 October 1998
View article titled, Cellular but not plasma pharmacokinetics of lometrexol correlate with the occurrence of cumulative hematological toxicity.
Open the PDF for Cellular but not plasma pharmacokinetics of lometrexol correlate with the occurrence of cumulative hematological toxicity. in another window
Journal Articles

p53 and thymidylate synthase expression in untreated stage II colon cancer: associations with recurrence, survival, and site.

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H J Lenz, K D Danenberg, C G Leichman, B Florentine, P G Johnston, S Groshen, L Zhou, Y P Xiong, P V Danenberg, L P Leichman
Journal: Clinical Cancer Research
Clin Cancer Res (1998) 4 (5): 1227–1234.
Published: 01 May 1998
View article titled, p53 and thymidylate synthase expression in untreated stage II colon cancer: associations with recurrence, survival, and site.
Open the PDF for p53 and thymidylate synthase expression in untreated stage II colon cancer: associations with recurrence, survival, and site. in another window
Journal Articles

p53 point mutations and thymidylate synthase messenger RNA levels in disseminated colorectal cancer: an analysis of response and survival.

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H J Lenz, K Hayashi, D Salonga, K D Danenberg, P V Danenberg, R Metzger, D Banerjee, J R Bertino, S Groshen, L P Leichman, C G Leichman
Journal: Clinical Cancer Research
Clin Cancer Res (1998) 4 (5): 1243–1250.
Published: 01 May 1998
View article titled, p53 point mutations and thymidylate synthase messenger RNA levels in disseminated colorectal cancer: an analysis of response and survival.
Open the PDF for p53 point mutations and thymidylate synthase messenger RNA levels in disseminated colorectal cancer: an analysis of response and survival. in another window
Journal Articles

Relationship of tumor angiogenesis and nuclear p53 accumulation in invasive bladder cancer.

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B H Bochner, D Esrig, S Groshen, M Dickinson, N Weidner, P W Nichols, D G Skinner, R J Cote
Journal: Clinical Cancer Research
Clin Cancer Res (1997) 3 (9): 1615–1622.
Published: 01 September 1997
View article titled, Relationship of tumor angiogenesis and nuclear p53 accumulation in invasive bladder cancer.
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Journal Articles

Phase I and pharmacokinetic study of oral UFT, a combination of the 5-fluorouracil prodrug tegafur and uracil.

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F M Muggia, X Wu, D Spicer, S Groshen, S Jeffers, C G Leichman, L Leichman, K K Chan
Journal: Clinical Cancer Research
Clin Cancer Res (1996) 2 (9): 1461–1467.
Published: 01 September 1996
View article titled, Phase I and pharmacokinetic study of oral UFT, a combination of the 5-fluorouracil prodrug tegafur and uracil.
Open the PDF for Phase I and pharmacokinetic study of oral UFT, a combination of the 5-fluorouracil prodrug tegafur and uracil. in another window