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Journal Articles

Comprehensive Molecular Characterization of Gallbladder Carcinoma and Potential Targets for Intervention

Nicolas A. Giraldo, Esther Drill, Baby A. Satravada, Imane El Dika, A. Rose Brannon, Josephine Dermawan, Abhinita Mohanty, Kerem Ozcan, Debyani Chakravarty, Ryma Benayed, Efsevia Vakiani, Ghassan K. Abou-Alfa, Ritika Kundra, Nikolaus Schultz, Bob T. Li, Michael F. Berger, James J. Harding, Marc Ladanyi, Eileen M. O'Reilly, William Jarnagin, Chad Vanderbilt, Olca Basturk, Maria E. Arcila
Journal: Clinical Cancer Research
Clin Cancer Res (2022) 28 (24): 5359–5367.
https://doi.org/10.1158/1078-0432.CCR-22-1954
Published: 15 December 2022
View article titled, Comprehensive Molecular Characterization of Gallbladder Carcinoma and Potential Targets for Intervention
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Includes: Supplementary data
Journal Articles

Abstract B023: Prospective clinical genomic profiling of ewing sarcoma: ERF and FGFR1 mutations as recurrent secondary alterations of potential biological and therapeutic relevance

Arielle Elkrief, Koichi Ogura, Anita S. Bowman, Richard P. Koche, Ryma Benayed, Audrey Mauguen, Marissa S. Mattar, Inna Khodos, Elisa de Stanchina, Paul A. Meyers, John H. Healey, William D. Tap, Neerav Shukla, Meera Hameed, Ahmet Zehir, Charles Sawyers, Rohit Bose, Emily Slotkin, Marc Ladanyi
Journal: Clinical Cancer Research
Clin Cancer Res (2022) 28 (18_Supplement): B023.
https://doi.org/10.1158/1557-3265.SARCOMAS22-B023
Published: 15 September 2022
View article titled, Abstract B023: Prospective clinical genomic profiling of ewing sarcoma: <em>ERF</em> and <em>FGFR1</em> mutations as recurrent secondary alterations of potential biological and therapeutic relevance
Journal Articles

Comprehensive Molecular and Clinicopathologic Analysis of 200 Pulmonary Invasive Mucinous Adenocarcinomas Identifies Distinct Characteristics of Molecular Subtypes

Jason C. Chang, Michael Offin, Christina Falcon, David Brown, Brian R. Houck-Loomis, Fanli Meng, Vasilisa A. Rudneva, Helen H. Won, Sharon Amir, Joseph Montecalvo, Patrice Desmeules, Kyuichi Kadota, Prasad S. Adusumilli, Valerie W. Rusch, Sarah Teed, Joshua K. Sabari, Ryma Benayed, Khedoudja Nafa, Laetitia Borsu, Bob T. Li, Alison M. Schram, Maria E. Arcila, William D. Travis, Marc Ladanyi, Alexander Drilon, Natasha Rekhtman
Journal: Clinical Cancer Research
Clin Cancer Res (2021) 27 (14): 4066–4076.
https://doi.org/10.1158/1078-0432.CCR-21-0423
Published: 15 July 2021
View article titled, Comprehensive Molecular and Clinicopathologic Analysis of 200 Pulmonary Invasive Mucinous Adenocarcinomas Identifies Distinct Characteristics of Molecular Subtypes
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Includes: Supplementary data
Journal Articles

A Performance Comparison of Commonly Used Assays to Detect RET Fusions

Soo-Ryum Yang, Umut Aypar, Ezra Y. Rosen, Douglas A. Mata, Ryma Benayed, Kerry Mullaney, Gowtham Jayakumaran, Yanming Zhang, Denise Frosina, Alexander Drilon, Marc Ladanyi, Achim A. Jungbluth, Natasha Rekhtman, Jaclyn F. Hechtman
Journal: Clinical Cancer Research
Clin Cancer Res (2021) 27 (5): 1316–1328.
https://doi.org/10.1158/1078-0432.CCR-20-3208
Published: 01 March 2021
View article titled, A Performance Comparison of Commonly Used Assays to Detect RET Fusions
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Includes: Supplementary data
Journal Articles

Therapeutic Potential of NTRK3 Inhibition in Desmoplastic Small Round Cell Tumor

Koichi Ogura, Romel Somwar, Julija Hmeljak, Heather Magnan, Ryma Benayed, Amir Momeni Boroujeni, Anita S. Bowman, Marissa S. Mattar, Inna Khodos, Elisa de Stanchina, Achim Jungbluth, Marina Asher, Igor Odintsov, Alifiani B. Hartono, Michael P. LaQuaglia, Emily Slotkin, Christine A. Pratilas, Sean Bong Lee, Lee Spraggon, Marc Ladanyi
Journal: Clinical Cancer Research
Clin Cancer Res (2021) 27 (4): 1184–1194.
https://doi.org/10.1158/1078-0432.CCR-20-2585
Published: 15 February 2021
View article titled, Therapeutic Potential of NTRK3 Inhibition in Desmoplastic Small Round Cell Tumor
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Includes: Supplementary data
Journal Articles

MET Exon 14–altered Lung Cancers and MET Inhibitor Resistance

Robin Guo, Michael Offin, A. Rose Brannon, Jason Chang, Andrew Chow, Lukas Delasos, Jeffrey Girshman, Olivia Wilkins, Caroline G. McCarthy, Alex Makhnin, Christina Falcon, Kerry Scott, Yuan Tian, Fabiola Cecchi, Todd Hembrough, Deepu Alex, Ronglai Shen, Ryma Benayed, Bob T. Li, Charles M. Rudin, Mark G. Kris, Maria E. Arcila, Natasha Rekhtman, Paul Paik, Ahmet Zehir, Alexander Drilon
Journal: Clinical Cancer Research
Clin Cancer Res (2021) 27 (3): 799–806.
https://doi.org/10.1158/1078-0432.CCR-20-2861
Published: 01 February 2021
View article titled, <em>MET</em> Exon 14–altered Lung Cancers and MET Inhibitor Resistance
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Includes: Supplementary data
Journal Articles

Abstract 16: Landscape and outcome of TRK fusion-positive Cancers

Ezra Y. Rosen, Debra A. Goldman, Jaclyn F. Hechtman, Ryma Benayed, Alison M. Schram, Emiliano Cocco, Sophie Shifman, Yixiao Gong, Ritika Kundra, James P. Solomon, Alberto Bardelli, Maurizio Scaltriti, Alexander Drilon, Alexia Iasonos, Barry S. Taylor, David M. Hyman
Journal: Clinical Cancer Research
Clin Cancer Res (2020) 26 (12_Supplement_1): 16.
https://doi.org/10.1158/1557-3265.ADVPRECMED20-16
Published: 15 June 2020
View article titled, Abstract 16: Landscape and outcome of TRK fusion-positive Cancers
Journal Articles

Abstract PR08: Validation and clinical implementation of MSK-ACCESS, an ultra-deep sequencing assay for noninvasive somatic mutation profiling

A. Rose Brannon, Gowtham Jayakumaran, Monica Diosdado, Yu Hu, Anna Razumova, Fanli Meng, Emily Lebow, Juber Patel, Ian Johnson, Preethi Srinivasan, Maysun Hasan, Jenna-marie Dix, Aijazuddin Syed, Brian Houck-Loomis, Bob T. Li, Charles Rudin, David Solit, Marc Ladanyi, Maria Arcila, Dana Tsui, Ahmet Zehir, Michael Berger, Ryma Benayed
Journal: Clinical Cancer Research
Clin Cancer Res (2020) 26 (11_Supplement): PR08.
https://doi.org/10.1158/1557-3265.LiqBiop20-PR08
Published: 01 June 2020
View article titled, Abstract PR08: Validation and clinical implementation of MSK-ACCESS, an ultra-deep sequencing assay for noninvasive somatic mutation profiling
Journal Articles

TRK Fusions Are Enriched in Cancers with Uncommon Histologies and the Absence of Canonical Driver Mutations

Ezra Y. Rosen, Debra A. Goldman, Jaclyn F. Hechtman, Ryma Benayed, Alison M. Schram, Emiliano Cocco, Sophie Shifman, Yixiao Gong, Ritika Kundra, James P. Solomon, Alberto Bardelli, Maurizio Scaltriti, Alexander Drilon, Alexia Iasonos, Barry S. Taylor, David M. Hyman
Journal: Clinical Cancer Research
Series: Author Choice
Clin Cancer Res (2020) 26 (7): 1624–1632.
https://doi.org/10.1158/1078-0432.CCR-19-3165
Published: 01 April 2020
View article titled, TRK Fusions Are Enriched in Cancers with Uncommon Histologies and the Absence of Canonical Driver Mutations
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Includes: Supplementary data
Journal Articles

Genomic Profiling Identifies Association of IDH1/IDH2 Mutation with Longer Relapse-Free and Metastasis-Free Survival in High-Grade Chondrosarcoma

Guo Gord Zhu, Khedoudja Nafa, Narasimhan Agaram, Ahmet Zehir, Ryma Benayed, Justyna Sadowska, Laetitia Borsu, Ciara Kelly, William D. Tap, Nicola Fabbri, Edward Athanasian, Patrick J. Boland, John H. Healey, Michael F. Berger, Marc Ladanyi, Meera Hameed
Journal: Clinical Cancer Research
Clin Cancer Res (2020) 26 (2): 419–427.
https://doi.org/10.1158/1078-0432.CCR-18-4212
Published: 15 January 2020
View article titled, Genomic Profiling Identifies Association of <em>IDH1/IDH2</em> Mutation with Longer Relapse-Free and Metastasis-Free Survival in High-Grade Chondrosarcoma
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Includes: Supplementary data
Journal Articles

High Yield of RNA Sequencing for Targetable Kinase Fusions in Lung Adenocarcinomas with No Mitogenic Driver Alteration Detected by DNA Sequencing and Low Tumor Mutation Burden

Ryma Benayed, Michael Offin, Kerry Mullaney, Purvil Sukhadia, Kelly Rios, Patrice Desmeules, Ryan Ptashkin, Helen Won, Jason Chang, Darragh Halpenny, Alison M. Schram, Charles M. Rudin, David M. Hyman, Maria E. Arcila, Michael F. Berger, Ahmet Zehir, Mark G. Kris, Alexander Drilon, Marc Ladanyi
Journal: Clinical Cancer Research
Clin Cancer Res (2019) 25 (15): 4712–4722.
https://doi.org/10.1158/1078-0432.CCR-19-0225
Published: 01 August 2019
View article titled, High Yield of RNA Sequencing for Targetable Kinase Fusions in Lung Adenocarcinomas with No Mitogenic Driver Alteration Detected by DNA Sequencing and Low Tumor Mutation Burden
Open the PDF for High Yield of RNA Sequencing for Targetable Kinase Fusions in Lung Adenocarcinomas with No Mitogenic Driver Alteration Detected by DNA Sequencing and Low Tumor Mutation Burden in another window
Includes: Supplementary data