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Russell R. Broaddus
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Journal Articles

Abstract B004: Investigating loss of ARID1A protein on endometrial cancer progression through the destabilization of adherens junctions

Savannah E. Wright, Isurika Weerasinghe, Russell R. Broaddus, Andrew B. Gladden
Journal: Clinical Cancer Research
Clin Cancer Res (2024) 30 (5_Supplement): B004.
https://doi.org/10.1158/1557-3265.ENDO24-B004
Published: 01 March 2024
View article titled, Abstract B004: Investigating loss of ARID1A protein on endometrial cancer progression through the destabilization of adherens junctions
Journal Articles

Abstract PR008: Location, location, location: Why cellular localization of mutant β-catenin matters in endometrial cancer

Molly L. Parrish, Andrew B. Gladden, Russell R. Broaddus
Journal: Clinical Cancer Research
Clin Cancer Res (2024) 30 (5_Supplement): PR008.
https://doi.org/10.1158/1557-3265.ENDO24-PR008
Published: 01 March 2024
View article titled, Abstract PR008: Location, location, location: Why cellular localization of mutant β-catenin matters in endometrial cancer
Journal Articles

Abstract PR007: Patient derived organoids as a model to study estrogen mediated endometrial cancer

Breanna M.W. Jeffcoat, Andrew B. Galdden, Russell R. Broaddus
Journal: Clinical Cancer Research
Clin Cancer Res (2024) 30 (5_Supplement): PR007.
https://doi.org/10.1158/1557-3265.ENDO24-PR007
Published: 01 March 2024
View article titled, Abstract PR007: Patient derived organoids as a model to study estrogen mediated endometrial cancer
Journal Articles

Abstract PR004: CD73 is a novel repressor of mutant β-catenin oncogenic activity in endometrial cancer

Rebecca M. Hirsch, Xingyuan Zhang, Lilly F. Chiou, Sunthoshini Premsankar, Hannah N. Lee, Katherine C. Kurnit, Russell R. Broaddus, Cyrus Vaziri, Jessica L. Bowser
Journal: Clinical Cancer Research
Clin Cancer Res (2024) 30 (5_Supplement): PR004.
https://doi.org/10.1158/1557-3265.ENDO24-PR004
Published: 01 March 2024
View article titled, Abstract PR004: CD73 is a novel repressor of mutant β-catenin oncogenic activity in endometrial cancer
Journal Articles

Abstract B023: The role of ribosomal protein L22 in regulating the immune landscape in mismatch repair deficient endometrial cancers

Macy L. Osborne, Hannah Atkins, Andrew B. Gladden, Russell R. Broaddus
Journal: Clinical Cancer Research
Clin Cancer Res (2024) 30 (5_Supplement): B023.
https://doi.org/10.1158/1557-3265.ENDO24-B023
Published: 01 March 2024
View article titled, Abstract B023: The role of ribosomal protein L22 in regulating the immune landscape in mismatch repair deficient endometrial cancers
Journal Articles

Abstract IA022: Harnessing the unique biology of CD73 for improving endometrial cancer outcomes

Jessica L. Bowser, Hannah N. Lee, Rebecca H. Hirsch, Xingyuan Zhang, Russell R. Broaddus, Katherine C. Kurnit, Suzanne M. Crumley, Sunthoshini Premsankar, Emily M. Rabjohns, Lilly F. Chiou, Cyrus Vaziri
Journal: Clinical Cancer Research
Clin Cancer Res (2024) 30 (5_Supplement): IA022.
https://doi.org/10.1158/1557-3265.ENDO24-IA022
Published: 01 March 2024
View article titled, Abstract IA022: Harnessing the unique biology of CD73 for improving endometrial cancer outcomes
Journal Articles

Clinical and Functional Characterization of Atypical KRAS/NRAS Mutations in Metastatic Colorectal Cancer

Jonathan M. Loree, Yucai Wang, Muddassir A. Syed, Alexey V. Sorokin, Oluwadara Coker, Joanne Xiu, Benjamin A. Weinberg, Ari M. Vanderwalde, Anteneh Tesfaye, Victoria M. Raymond, Benjamin Miron, Gabi Tarcic, Ori Zelichov, Russell R. Broaddus, Patrick Kwok Shing Ng, Kang Jin Jeong, Yiu Huen Tsang, Gordon B. Mills, Michael J. Overman, Axel Grothey, John L. Marshall, Scott Kopetz
Journal: Clinical Cancer Research
Clin Cancer Res (2021) 27 (16): 4587–4598.
https://doi.org/10.1158/1078-0432.CCR-21-0180
Published: 15 August 2021
View article titled, Clinical and Functional Characterization of Atypical <em>KRAS</em>/<em>NRAS</em> Mutations in Metastatic Colorectal Cancer
Open the PDF for Clinical and Functional Characterization of Atypical <em>KRAS</em>/<em>NRAS</em> Mutations in Metastatic Colorectal Cancer in another window
Includes: Supplementary data
Journal Articles

Abstract PR005: CD73 sequestering mutant β-catenin at the membrane explains recurrence in CTNNB1 mutant endometrial cancer

Jessica L. Bowser, Katherine C. Kurnit, Luan H. Phan, Jerry B. Harvey, Jiping Feng, SuSu Xie, Andrew B. Gladden, Pierre D. McCrea, Russell R. Broaddus
Journal: Clinical Cancer Research
Clin Cancer Res (2021) 27 (3_Supplement): PR005.
https://doi.org/10.1158/1557-3265.ENDOMET20-PR005
Published: 01 February 2021
View article titled, Abstract PR005: CD73 sequestering mutant β-catenin at the membrane explains recurrence in <em>CTNNB1</em> mutant endometrial cancer
Journal Articles

Abstract IA008: Mismatch repair deficiency and survival in stage I endometrial cancer

Russell R. Broaddus
Journal: Clinical Cancer Research
Clin Cancer Res (2021) 27 (3_Supplement): IA008.
https://doi.org/10.1158/1557-3265.ENDOMET20-IA008
Published: 01 February 2021
View article titled, Abstract IA008: Mismatch repair deficiency and survival in stage I endometrial cancer
Journal Articles

Everolimus, Letrozole, and Metformin in Women with Advanced or Recurrent Endometrioid Endometrial Cancer: A Multi-Center, Single Arm, Phase II Study

Pamela T. Soliman, Shannon N. Westin, David A. Iglesias, Bryan M. Fellman, Ying Yuan, Qian Zhang, Melinda S. Yates, Russell R. Broaddus, Brian M. Slomovitz, Karen H. Lu, Robert L. Coleman
Journal: Clinical Cancer Research
Clin Cancer Res (2020) 26 (3): 581–587.
https://doi.org/10.1158/1078-0432.CCR-19-0471
Published: 03 February 2020
View article titled, Everolimus, Letrozole, and Metformin in Women with Advanced or Recurrent Endometrioid Endometrial Cancer: A Multi-Center, Single Arm, Phase II Study
Open the PDF for Everolimus, Letrozole, and Metformin in Women with Advanced or Recurrent Endometrioid Endometrial Cancer: A Multi-Center, Single Arm, Phase II Study in another window
Includes: Supplementary data
Journal Articles

Immune Microenvironment in Microsatellite-Instable Endometrial Cancers: Hereditary or Sporadic Origin Matters

Janelle B. Pakish, Qian Zhang, Zhongyuan Chen, Han Liang, Gary B. Chisholm, Ying Yuan, Samuel C. Mok, Russell R. Broaddus, Karen H. Lu, Melinda S. Yates
Journal: Clinical Cancer Research
Clin Cancer Res (2017) 23 (15): 4473–4481.
https://doi.org/10.1158/1078-0432.CCR-16-2655
Published: 01 August 2017
View article titled, Immune Microenvironment in Microsatellite-Instable Endometrial Cancers: Hereditary or Sporadic Origin Matters
Open the PDF for Immune Microenvironment in Microsatellite-Instable Endometrial Cancers: Hereditary or Sporadic Origin Matters in another window
Includes: Supplementary data
Journal Articles

Abstract B23: Dominant stablized ß-catenin induces adenomyosis formation and ablation of Mig-6 accelerates progress of adenomyosis formation

Jung-Ho Shin, Tae Hoon Kim, Michael J. Large, Sung Nam Cho, Seo Jin Oh, Jeong Mook Lim, Makoto M. Taketo, Russell R. Broaddus, Jae-Wook Jeong
Journal: Clinical Cancer Research
Clin Cancer Res (2010) 16 (14_Supplement): B23.
https://doi.org/10.1158/1078-0432.TCMUSA10-B23
Published: 02 February 2016
View article titled, Abstract B23: Dominant stablized ß-catenin induces adenomyosis formation and ablation of <em>Mig-6</em> accelerates progress of adenomyosis formation
Journal Articles

Hotspot Mutation Panel Testing Reveals Clonal Evolution in a Study of 265 Paired Primary and Metastatic Tumors

Rashmi S. Goswami, Keyur P. Patel, Rajesh R. Singh, Funda Meric-Bernstam, E. Scott Kopetz, Vivek Subbiah, Ricardo H. Alvarez, Michael A. Davies, Kausar J. Jabbar, Sinchita Roy-Chowdhuri, Alexander J. Lazar, L. Jeffrey Medeiros, Russell R. Broaddus, Rajyalakshmi Luthra, Mark J. Routbort
Journal: Clinical Cancer Research
Clin Cancer Res (2015) 21 (11): 2644–2651.
https://doi.org/10.1158/1078-0432.CCR-14-2391
Published: 31 May 2015
View article titled, Hotspot Mutation Panel Testing Reveals Clonal Evolution in a Study of 265 Paired Primary and Metastatic Tumors
Open the PDF for Hotspot Mutation Panel Testing Reveals Clonal Evolution in a Study of 265 Paired Primary and Metastatic Tumors in another window
Includes: Supplementary data
Journal Articles

Abstract B73: Human omental-derived adipose stem cells: Modulator of ovarian cancer proliferation, migration and chemoresistance

Aleksandra Nowicka, Travis Solley, Frank C. Marini, Hadley J. Sharp, Russell R. Broaddus, Kolonin G. Mikhail, Samuel C. Mok, Wendy A. Woodward, Karen H. Lu, Ann H. Klopp
Journal: Clinical Cancer Research
Clin Cancer Res (2013) 19 (19_Supplement): B73.
https://doi.org/10.1158/1078-0432.OVCA13-B73
Published: 13 May 2014
View article titled, Abstract B73: Human omental-derived adipose stem cells: Modulator of ovarian cancer proliferation, migration and chemoresistance
Journal Articles

Loss of Tuberous Sclerosis Complex-2 Function and Activation of Mammalian Target of Rapamycin Signaling in Endometrial Carcinoma

Karen H. Lu, Weiguo Wu, Bhuvanesh Dave, Brian M. Slomovitz, Thomas W. Burke, Mark F. Munsell, Russell R. Broaddus, Cheryl Lyn Walker
Journal: Clinical Cancer Research
Clin Cancer Res (2008) 14 (9): 2543–2550.
https://doi.org/10.1158/1078-0432.CCR-07-0321
Published: 01 May 2008
View article titled, Loss of Tuberous Sclerosis Complex-2 Function and Activation of Mammalian Target of Rapamycin Signaling in Endometrial Carcinoma
Open the PDF for Loss of Tuberous Sclerosis Complex-2 Function and Activation of Mammalian Target of Rapamycin Signaling in Endometrial Carcinoma in another window
Includes: Supplementary data
Journal Articles

Overexpression of the Insulin-Like Growth Factor I Receptor and Activation of the AKT Pathway in Hyperplastic Endometrium

Adrienne S. McCampbell, Russell R. Broaddus, David S. Loose, Peter J.A. Davies
Journal: Clinical Cancer Research
Clin Cancer Res (2006) 12 (21): 6373–6378.
https://doi.org/10.1158/1078-0432.CCR-06-0912
Published: 03 November 2006
View article titled, Overexpression of the Insulin-Like Growth Factor I Receptor and Activation of the AKT Pathway in Hyperplastic Endometrium
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Journal Articles

Identification of a Novel Estrogen-Regulated Gene, EIG121, Induced by Hormone Replacement Therapy and Differentially Expressed in Type I and Type II Endometrial Cancer

Lei Deng, Russell R. Broaddus, Adrienne McCampbell, Gregory L. Shipley, David S. Loose, George M. Stancel, James H. Pickar, Peter J.A. Davies
Journal: Clinical Cancer Research
Clin Cancer Res (2005) 11 (23): 8258–8264.
https://doi.org/10.1158/1078-0432.CCR-05-1189
Published: 01 December 2005
View article titled, Identification of a Novel Estrogen-Regulated Gene, <em>EIG121</em>, Induced by Hormone Replacement Therapy and Differentially Expressed in Type I and Type II Endometrial Cancer
Open the PDF for Identification of a Novel Estrogen-Regulated Gene, <em>EIG121</em>, Induced by Hormone Replacement Therapy and Differentially Expressed in Type I and Type II Endometrial Cancer in another window