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Rosa Lapalombella
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Journal Articles

Selinexor Combined with Ibrutinib Demonstrates Tolerability and Safety in Advanced B-Cell Malignancies: A Phase I Study

Deborah M. Stephens, Ying Huang, Amy S. Ruppert, Janek S. Walker, Daniel Canfield, Casey B. Cempre, Qiang Fu, Sharyn Baker, Boyu Hu, Harsh Shah, Renee Vadeboncoeur, Kerry A. Rogers, Seema Bhat, Samantha M. Jaglowski, Hank Lockman, Rosa Lapalombella, John C. Byrd, Jennifer A. Woyach
Journal: Clinical Cancer Research
Clin Cancer Res (2022) 28 (15): 3242–3247.
https://doi.org/10.1158/1078-0432.CCR-21-3867
Published: 02 August 2022
View article titled, Selinexor Combined with Ibrutinib Demonstrates Tolerability and Safety in Advanced B-Cell Malignancies: A Phase I Study
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Includes: Supplementary data
Journal Articles

Targeting DNA Damage Repair Functions of Two Histone Deacetylases, HDAC8 and SIRT6, Sensitizes Acute Myeloid Leukemia to NAMPT Inhibition

Pu Zhang, Lindsey T. Brinton, Katie Williams, Steven Sher, Shelley Orwick, Lai Tzung-Huei, Alice S. Mims, Christopher C. Coss, Samuel K. Kulp, Youssef Youssef, Wing Keung Chan, Shaneice Mitchell, Allison Mustonen, Matthew Cannon, Hannah Phillips, Amy M. Lehman, Tierney Kauffman, Larry Beaver, Daniel Canfield, Nicole R. Grieselhuber, Lapo Alinari, Deepa Sampath, Pearlly Yan, John C. Byrd, James S. Blachly, Rosa Lapalombella
Journal: Clinical Cancer Research
Clin Cancer Res (2021) 27 (8): 2352–2366.
https://doi.org/10.1158/1078-0432.CCR-20-3724
Published: 15 April 2021
View article titled, Targeting DNA Damage Repair Functions of Two Histone Deacetylases, HDAC8 and SIRT6, Sensitizes Acute Myeloid Leukemia to NAMPT Inhibition
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Includes: Supplementary data
Journal Articles

Eμ-TCL1xMyc: A Novel Mouse Model for Concurrent CLL and B-Cell Lymphoma

Fabienne Lucas, Kerry A. Rogers, Bonnie K. Harrington, Alexander Pan, Lianbo Yu, Justin Breitbach, Ralf Bundschuh, Virginia M. Goettl, Zachary A. Hing, Parviz Kanga, Rose Mantel, Deepa Sampath, Lisa L. Smith, Ronni Wasmuth, Danielle K. White, Pearlly Yan, John C. Byrd, Rosa Lapalombella, Jennifer A. Woyach
Journal: Clinical Cancer Research
Clin Cancer Res (2019) 25 (20): 6260–6273.
https://doi.org/10.1158/1078-0432.CCR-19-0273
Published: 15 October 2019
View article titled, Eμ-TCL1xMyc: A Novel Mouse Model for Concurrent CLL and B-Cell Lymphoma
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Includes: Supplementary data
Journal Articles

The Proteasome Inhibitor Carfilzomib Functions Independently of p53 to Induce Cytotoxicity and an Atypical NF-κB Response in Chronic Lymphocytic Leukemia Cells

Sneha V. Gupta, Erin Hertlein, Yanhui Lu, Ellen J. Sass, Rosa Lapalombella, Timothy L. Chen, Melanie E. Davis, Jennifer A. Woyach, Amy Lehman, David Jarjoura, John C. Byrd, David M. Lucas
Journal: Clinical Cancer Research
Clin Cancer Res (2013) 19 (9): 2406–2419.
https://doi.org/10.1158/1078-0432.CCR-12-2754
Published: 30 April 2013
View article titled, The Proteasome Inhibitor Carfilzomib Functions Independently of p53 to Induce Cytotoxicity and an Atypical NF-κB Response in Chronic Lymphocytic Leukemia Cells
Open the PDF for The Proteasome Inhibitor Carfilzomib Functions Independently of p53 to Induce Cytotoxicity and an Atypical NF-κB Response in Chronic Lymphocytic Leukemia Cells in another window
Includes: Supplementary data
Journal Articles

FTY720 Shows Promising In vitro and In vivo Preclinical Activity by Downmodulating Cyclin D1 and Phospho-Akt in Mantle Cell Lymphoma

Qing Liu, Lapo Alinari, Ching-Shih Chen, Fengting Yan, James T. Dalton, Rosa Lapalombella, Xiaoli Zhang, Rajeswaran Mani, Teresa Lin, John C. Byrd, Robert A. Baiocchi, Natarajan Muthusamy
Journal: Clinical Cancer Research
Clin Cancer Res (2010) 16 (12): 3182–3192.
https://doi.org/10.1158/1078-0432.CCR-09-2484
Published: 14 June 2010
View article titled, FTY720 Shows Promising <em>In vitro</em> and <em>In vivo</em> Preclinical Activity by Downmodulating Cyclin D1 and Phospho-Akt in Mantle Cell Lymphoma
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Journal Articles

A Novel Raji-Burkitt's Lymphoma Model for Preclinical and Mechanistic Evaluation of CD52-Targeted Immunotherapeutic Agents

Rosa Lapalombella, Xiaobin Zhao, Georgia Triantafillou, Bo Yu, Yan Jin, Gerard Lozanski, Carolyn Cheney, Nyla Heerema, David Jarjoura, Amy Lehman, L. James Lee, Guido Marcucci, Robert J. Lee, Michael A. Caligiuri, Natarajan Muthusamy, John C. Byrd
Journal: Clinical Cancer Research
Clin Cancer Res (2008) 14 (2): 569–578.
https://doi.org/10.1158/1078-0432.CCR-07-1006
Published: 25 January 2008
View article titled, A Novel Raji-Burkitt's Lymphoma Model for Preclinical and Mechanistic Evaluation of CD52-Targeted Immunotherapeutic Agents
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