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Robert M. Prins
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Journal Articles

Advanced Age Increases Immunosuppression in the Brain and Decreases Immunotherapeutic Efficacy in Subjects with Glioblastoma

Erik Ladomersky, Lijie Zhai, Kristen L. Lauing, April Bell, Jiahui Xu, Masha Kocherginsky, Bin Zhang, Jennifer D. Wu, Joseph R. Podojil, Leonidas C. Platanias, Aaron Y. Mochizuki, Robert M. Prins, Priya Kumthekar, Jeffrey J. Raizer, Karan Dixit, Rimas V. Lukas, Craig Horbinski, Min Wei, Changyou Zhou, Graham Pawelec, Judith Campisi, Ursula Grohmann, George C. Prendergast, David H. Munn, Derek A. Wainwright
Journal: Clinical Cancer Research
Clin Cancer Res (2020) 26 (19): 5232–5245.
https://doi.org/10.1158/1078-0432.CCR-19-3874
Published: 01 October 2020
View article titled, Advanced Age Increases Immunosuppression in the Brain and Decreases Immunotherapeutic Efficacy in Subjects with Glioblastoma
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Includes: Supplementary data
Journal Articles

Expression of PD-1 by T Cells in Malignant Glioma Patients Reflects Exhaustion and Activation

Tom B. Davidson, Alexander Lee, Melody Hsu, Shaina Sedighim, Joey Orpilla, Janet Treger, Max Mastall, Saskia Roesch, Carmen Rapp, Mildred Galvez, Aaron Mochizuki, Joseph Antonios, Alejandro Garcia, Nikesh Kotecha, Nicholas Bayless, David Nathanson, Anthony Wang, Richard Everson, William H. Yong, Timothy F. Cloughesy, Linda M. Liau, Christel Herold-Mende, Robert M. Prins
Journal: Clinical Cancer Research
Clin Cancer Res (2019) 25 (6): 1913–1922.
https://doi.org/10.1158/1078-0432.CCR-18-1176
Published: 15 March 2019
View article titled, Expression of PD-1 by T Cells in Malignant Glioma Patients Reflects Exhaustion and Activation
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Includes: Supplementary data
Journal Articles

Cytokines Produced by Dendritic Cells Administered Intratumorally Correlate with Clinical Outcome in Patients with Diverse Cancers

Vivek Subbiah, Ravi Murthy, David S. Hong, Robert M. Prins, Chitra Hosing, Kyle Hendricks, Deepthi Kolli, Lori Noffsinger, Robert Brown, Mary McGuire, Siquing Fu, Sarina Piha-Paul, Aung Naing, Anthony P. Conley, Robert S. Benjamin, Indreshpal Kaur, Marnix L. Bosch
Journal: Clinical Cancer Research
Series: Author Choice
Clin Cancer Res (2018) 24 (16): 3845–3856.
https://doi.org/10.1158/1078-0432.CCR-17-2707
Published: 14 August 2018
View article titled, Cytokines Produced by Dendritic Cells Administered Intratumorally Correlate with Clinical Outcome in Patients with Diverse Cancers
Open the PDF for Cytokines Produced by Dendritic Cells Administered Intratumorally Correlate with Clinical Outcome in Patients with Diverse Cancers in another window
Includes: Supplementary data
Journal Articles

Gene Expression Profile Correlates with T-Cell Infiltration and Relative Survival in Glioblastoma Patients Vaccinated with Dendritic Cell Immunotherapy

Robert M. Prins, Horacio Soto, Vera Konkankit, Sylvia K. Odesa, Ascia Eskin, William H. Yong, Stanley F. Nelson, Linda M. Liau
Journal: Clinical Cancer Research
Clin Cancer Res (2011) 17 (6): 1603–1615.
https://doi.org/10.1158/1078-0432.CCR-10-2563
Published: 15 March 2011
View article titled, Gene Expression Profile Correlates with T-Cell Infiltration and Relative Survival in Glioblastoma Patients Vaccinated with Dendritic Cell Immunotherapy
Open the PDF for Gene Expression Profile Correlates with T-Cell Infiltration and Relative Survival in Glioblastoma Patients Vaccinated with Dendritic Cell Immunotherapy in another window
Includes: Supplementary data
Journal Articles

Dendritic Cell Vaccination in Glioblastoma Patients Induces Systemic and Intracranial T-cell Responses Modulated by the Local Central Nervous System Tumor Microenvironment

Linda M. Liau, Robert M. Prins, Sylvia M. Kiertscher, Sylvia K. Odesa, Thomas J. Kremen, Adrian J. Giovannone, Jia-Wei Lin, Dennis J. Chute, Paul S. Mischel, Timothy F. Cloughesy, Michael D. Roth
Journal: Clinical Cancer Research
Clin Cancer Res (2005) 11 (15): 5515–5525.
https://doi.org/10.1158/1078-0432.CCR-05-0464
Published: 01 August 2005
View article titled, Dendritic Cell Vaccination in Glioblastoma Patients Induces Systemic and Intracranial T-cell Responses Modulated by the Local Central Nervous System Tumor Microenvironment
Open the PDF for Dendritic Cell Vaccination in Glioblastoma Patients Induces Systemic and Intracranial T-cell Responses Modulated by the Local Central Nervous System Tumor Microenvironment in another window