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Robert B. Diasio
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Journal Articles

Polymorphisms in MIR27A Associated with Early-Onset Toxicity in Fluoropyrimidine-Based Chemotherapy

Ursula Amstutz, Steven M. Offer, Johanna Sistonen, Markus Joerger, Robert B. Diasio, Carlo R. Largiadèr
Journal: Clinical Cancer Research
Clin Cancer Res (2015) 21 (9): 2038–2044.
https://doi.org/10.1158/1078-0432.CCR-14-2817
Published: 30 April 2015
View article titled, Polymorphisms in <em>MIR27A</em> Associated with Early-Onset Toxicity in Fluoropyrimidine-Based Chemotherapy
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Includes: Supplementary data
Journal Articles

Association Study of the let-7 miRNA-Complementary Site Variant in the 3′ Untranslated Region of the KRAS Gene in Stage III Colon Cancer (NCCTG N0147 Clinical Trial)

Dan Sha, Adam M. Lee, Qian Shi, Steven R. Alberts, Daniel J. Sargent, Frank A. Sinicrope, Robert B. Diasio
Journal: Clinical Cancer Research
Clin Cancer Res (2014) 20 (12): 3319–3327.
https://doi.org/10.1158/1078-0432.CCR-14-0069
Published: 12 June 2014
View article titled, Association Study of the let-7 miRNA-Complementary Site Variant in the 3′ Untranslated Region of the <em>KRAS</em> Gene in Stage III Colon Cancer (NCCTG N0147 Clinical Trial)
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Journal Articles

Association of HER2/ErbB2 Expression and Gene Amplification with Pathologic Features and Prognosis in Esophageal Adenocarcinomas

Harry H. Yoon, Qian Shi, William R. Sukov, Anne E. Wiktor, Maliha Khan, Christopher A. Sattler, Axel Grothey, Tsung-Teh Wu, Robert B. Diasio, Robert B. Jenkins, Frank A. Sinicrope
Journal: Clinical Cancer Research
Clin Cancer Res (2012) 18 (2): 546–554.
https://doi.org/10.1158/1078-0432.CCR-11-2272
Published: 16 January 2012
View article titled, Association of HER2/ErbB2 Expression and Gene Amplification with Pathologic Features and Prognosis in Esophageal Adenocarcinomas
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Includes: Supplementary data
Journal Articles

A Phase I, Pharmacokinetic, and Pharmacodynamic Study of Two Schedules of Vorinostat in Combination with 5-Fluorouracil and Leucovorin in Patients with Refractory Solid Tumors

Marwan G. Fakih, Gerald Fetterly, Merrill J. Egorin, Josephia R. Muindi, Igor Espinoza-Delgado, James A. Zwiebel, Alan Litwin, Julianne L. Holleran, Kangsheng Wang, Robert B. Diasio
Journal: Clinical Cancer Research
Clin Cancer Res (2010) 16 (14): 3786–3794.
https://doi.org/10.1158/1078-0432.CCR-10-0547
Published: 14 July 2010
View article titled, A Phase I, Pharmacokinetic, and Pharmacodynamic Study of Two Schedules of Vorinostat in Combination with 5-Fluorouracil and Leucovorin in Patients with Refractory Solid Tumors
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Journal Articles

ADAM-17: A Target to Increase Chemotherapeutic Efficacy in Colorectal Cancer?

Adam M. Lee, Robert B. Diasio
Journal: Clinical Cancer Research
Clin Cancer Res (2010) 16 (13): 3319–3321.
https://doi.org/10.1158/1078-0432.CCR-10-1059
Published: 30 June 2010
View article titled, ADAM-17: A Target to Increase Chemotherapeutic Efficacy in Colorectal Cancer?
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Includes: Supplementary data
Journal Articles

Increased Prevalence of Dihydropyrimidine Dehydrogenase Deficiency in African-Americans Compared with Caucasians

Lori Kay Mattison, Jeanne Fourie, Renee A. Desmond, Anil Modak, Muhammad Wasif Saif, Robert B. Diasio
Journal: Clinical Cancer Research
Clin Cancer Res (2006) 12 (18): 5491–5495.
https://doi.org/10.1158/1078-0432.CCR-06-0747
Published: 25 September 2006
View article titled, Increased Prevalence of Dihydropyrimidine Dehydrogenase Deficiency in African-Americans Compared with Caucasians
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Journal Articles

Genetic Testing in Cancer Therapeutics

Hany H. Ezzeldin, Robert B. Diasio
Journal: Clinical Cancer Research
Clin Cancer Res (2006) 12 (14): 4137–4141.
https://doi.org/10.1158/1078-0432.CCR-06-0707
Published: 20 July 2006
View article titled, Genetic Testing in Cancer Therapeutics
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Journal Articles

The Uracil Breath Test in the Assessment of Dihydropyrimidine Dehydrogenase Activity: Pharmacokinetic Relationship between Expired 13CO2 and Plasma [2-13C]Dihydrouracil

Lori K. Mattison, Jeanne Fourie, Yukihiro Hirao, Toshihisa Koga, Renee A. Desmond, Jennifer R. King, Takefumi Shimizu, Robert B. Diasio
Journal: Clinical Cancer Research
Clin Cancer Res (2006) 12 (2): 549–555.
https://doi.org/10.1158/1078-0432.CCR-05-2020
Published: 20 January 2006
View article titled, The Uracil Breath Test in the Assessment of Dihydropyrimidine Dehydrogenase Activity: Pharmacokinetic Relationship between Expired <sup>13</sup>CO<sub>2</sub> and Plasma [2-<sup>13</sup>C]Dihydrouracil
Open the PDF for The Uracil Breath Test in the Assessment of Dihydropyrimidine Dehydrogenase Activity: Pharmacokinetic Relationship between Expired <sup>13</sup>CO<sub>2</sub> and Plasma [2-<sup>13</sup>C]Dihydrouracil in another window
Journal Articles

Methylation of the DPYD Promoter: An Alternative Mechanism for Dihydropyrimidine Dehydrogenase Deficiency in Cancer Patients

Hany H. Ezzeldin, Adam M. Lee, Lori K. Mattison, Robert B. Diasio
Journal: Clinical Cancer Research
Clin Cancer Res (2005) 11 (24): 8699–8705.
https://doi.org/10.1158/1078-0432.CCR-05-1520
Published: 16 December 2005
View article titled, Methylation of the <em>DPYD</em> Promoter: An Alternative Mechanism for Dihydropyrimidine Dehydrogenase Deficiency in Cancer Patients
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Journal Articles

Antitumor Efficacy of Capecitabine and Celecoxib in Irradiated and Lead-Shielded, Contralateral Human BxPC-3 Pancreatic Cancer Xenografts: Clinical Implications of Abscopal Effects

Carmelo Blanquicett, M. Wasif Saif, Donald J. Buchsbaum, Mohamad Eloubeidi, Selwyn M. Vickers, David C. Chhieng, Mark D. Carpenter, Jeffrey C. Sellers, Suzanne Russo, Robert B. Diasio, Martin R. Johnson
Journal: Clinical Cancer Research
Clin Cancer Res (2005) 11 (24): 8773–8781.
https://doi.org/10.1158/1078-0432.CCR-05-0627
Published: 16 December 2005
View article titled, Antitumor Efficacy of Capecitabine and Celecoxib in Irradiated and Lead-Shielded, Contralateral Human BxPC-3 Pancreatic Cancer Xenografts: Clinical Implications of Abscopal Effects
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Journal Articles

Rapid Identification of Dihydropyrimidine Dehydrogenase Deficiency by Using a Novel 2-13C-Uracil Breath Test

Lori K. Mattison, Hany Ezzeldin, Mark Carpenter, Anil Modak, Martin R. Johnson, Robert B. Diasio
Journal: Clinical Cancer Research
Clin Cancer Res (2004) 10 (8): 2652–2658.
https://doi.org/10.1158/1078-0432.CCR-03-0374
Published: 20 April 2004
View article titled, Rapid Identification of Dihydropyrimidine Dehydrogenase Deficiency by Using a Novel 2-<sup>13</sup>C-Uracil Breath Test
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Journal Articles

Capecitabine Induces Rapid, Sustained Response in Two Patients with Extensive Oral Verrucous Carcinoma

Anastasios Salesiotis, Richie Soong, Robert B. Diasio, Andra Frost, Kevin J. Cullen
Journal: Clinical Cancer Research
Clin Cancer Res (2003) 9 (2): 580–585.
Published: 01 February 2003
View article titled, Capecitabine Induces Rapid, Sustained Response in Two Patients with Extensive Oral Verrucous Carcinoma
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Journal Articles

Profound Dihydropyrimidine Dehydrogenase Deficiency Resulting from a Novel Compound Heterozygote Genotype

Martin R. Johnson, Kangsheng Wang, Robert B. Diasio
Journal: Clinical Cancer Research
Clin Cancer Res (2002) 8 (3): 768–774.
Published: 01 March 2002
View article titled, Profound Dihydropyrimidine Dehydrogenase Deficiency Resulting from a Novel Compound Heterozygote Genotype
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Journal Articles

Colorectal Tumors Responding to 5-Fluorouracil Have Low Gene Expression Levels of Dihydropyrimidine Dehydrogenase, Thymidylate Synthase, and Thymidine Phosphorylase

Dennis Salonga, Kathleen D. Danenberg, Martin Johnson, Ralf Metzger, Susan Groshen, Denice D. Tsao-Wei, Heinz-Josef Lenz, C. Gail Leichman, Lawrence Leichman, Robert B. Diasio, Peter V. Danenberg
Journal: Clinical Cancer Research
Clin Cancer Res (2000) 6 (4): 1322–1327.
Published: 01 April 2000
View article titled, Colorectal Tumors Responding to 5-Fluorouracil Have Low Gene Expression Levels of Dihydropyrimidine Dehydrogenase, Thymidylate Synthase, and Thymidine Phosphorylase
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Journal Articles

Dihydropyrimidine Dehydrogenase: Its Role in 5-Fluorouracil Clinical Toxicity and Tumor Resistance

Robert B. Diasio, Martin R. Johnson
Journal: Clinical Cancer Research
Clin Cancer Res (1999) 5 (10): 2672–2673.
Published: 01 October 1999
View article titled, Dihydropyrimidine Dehydrogenase: Its Role in 5-Fluorouracil Clinical Toxicity and Tumor Resistance
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Journal Articles

Life-Threatening Toxicity in a Dihydropyrimidine Dehydrogenase-deficient Patient after Treatment with Topical 5-Fluorouracil

Martin R. Johnson, Alexander Hageboutros, Kangsheng Wang, Lisa High, Jeffrey B. Smith, Robert B. Diasio
Journal: Clinical Cancer Research
Clin Cancer Res (1999) 5 (8): 2006–2011.
Published: 01 August 1999
View article titled, Life-Threatening Toxicity in a Dihydropyrimidine Dehydrogenase-deficient Patient after Treatment with Topical 5-Fluorouracil
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