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Robert B. Den
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Journal Articles

Correction: The Retinoblastoma Tumor Suppressor Modulates DNA Repair and Radioresponsiveness

Chellappagounder Thangavel, Ettickan Boopathi, Steve Ciment, Yi Liu, Raymond O’Neill, Ankur Sharma, Steve B. McMahon, Hestia Mellert, Sankar Addya, Adam Ertel, Ruth Birbe, Paolo Fortina, Adam P. Dicker, Karen E. Knudsen, Robert B. Den
Journal: Clinical Cancer Research
Clin Cancer Res (2024) 30 (24): 5695.
https://doi.org/10.1158/1078-0432.CCR-24-3735
Published: 16 December 2024
View article titled, Correction: The Retinoblastoma Tumor Suppressor Modulates DNA Repair and Radioresponsiveness
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Includes: Supplementary data
Journal Articles

Comparative Genomics Reveals Distinct Immune-oncologic Pathways in African American Men with Prostate Cancer

Shivanshu Awasthi, Anders Berglund, Julieta Abraham-Miranda, Robert J. Rounbehler, Kevin Kensler, Amparo Serna, Adriana Vidal, Sungyong You, Michael R. Freeman, Elai Davicioni, Yang Liu, R. Jeffrey Karnes, Eric A. Klein, Robert B. Den, Bruce J. Trock, Joshua D. Campbell, David J. Einstein, Raavi Gupta, Steven Balk, Priti Lal, Jong Y. Park, John L. Cleveland, Timothy R. Rebbeck, Stephen J. Freedland, Kosj Yamoah
Journal: Clinical Cancer Research
Clin Cancer Res (2021) 27 (1): 320–329.
https://doi.org/10.1158/1078-0432.CCR-20-2925
Published: 04 January 2021
View article titled, Comparative Genomics Reveals Distinct Immune-oncologic Pathways in African American Men with Prostate Cancer
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Includes: Supplementary data
Journal Articles

Transcriptomic Heterogeneity of Androgen Receptor Activity Defines a de novo low AR-Active Subclass in Treatment Naïve Primary Prostate Cancer

Daniel E. Spratt, Mohammed Alshalalfa, Nick Fishbane, Adam B. Weiner, Rohit Mehra, Brandon A. Mahal, Jonathan Lehrer, Yang Liu, Shuang G. Zhao, Corey Speers, Todd M. Morgan, Adam P. Dicker, Stephen J. Freedland, R. Jeffery Karnes, Sheila Weinmann, Elai Davicioni, Ashley E. Ross, Robert B. Den, Paul L. Nguyen, Felix Y. Feng, Tamara L. Lotan, Arul M. Chinnaiyan, Edward M. Schaeffer
Journal: Clinical Cancer Research
Clin Cancer Res (2019) 25 (22): 6721–6730.
https://doi.org/10.1158/1078-0432.CCR-19-1587
Published: 15 November 2019
View article titled, Transcriptomic Heterogeneity of Androgen Receptor Activity Defines a <em>de novo</em> low AR-Active Subclass in Treatment Naïve Primary Prostate Cancer
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Includes: Supplementary data
Journal Articles

Development and Validation of a Prostate Cancer Genomic Signature that Predicts Early ADT Treatment Response Following Radical Prostatectomy

R. Jeffrey Karnes, Vidit Sharma, Voleak Choeurng, Hussam Al-Deen Ashab, Nicholas Erho, Mohammed Alshalalfa, Bruce Trock, Ashley Ross, Kasra Yousefi, Harrison Tsai, Shuang G. Zhao, Jeffrey J. Tosoian, Zaid Haddad, Mandeep Takhar, S. Laura Chang, Daniel E. Spratt, Firas Abdollah, Robert B. Jenkins, Eric A. Klein, Paul L. Nguyen, Adam P. Dicker, Robert B. Den, Elai Davicioni, Felix Y. Feng, Tamara L. Lotan, Edward M. Schaeffer
Journal: Clinical Cancer Research
Series: Author Choice
Clin Cancer Res (2018) 24 (16): 3908–3916.
https://doi.org/10.1158/1078-0432.CCR-17-2745
Published: 14 August 2018
View article titled, Development and Validation of a Prostate Cancer Genomic Signature that Predicts Early ADT Treatment Response Following Radical Prostatectomy
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Includes: Supplementary data
Journal Articles

Therapeutic Challenge with a CDK 4/6 Inhibitor Induces an RB-Dependent SMAC-Mediated Apoptotic Response in Non–Small Cell Lung Cancer

Chellappagounder Thangavel, Ettickan Boopathi, Yi Liu, Christopher McNair, Alex Haber, Maryna Perepelyuk, Anshul Bhardwaj, Sankar Addya, Adam Ertel, Sunday Shoyele, Ruth Birbe, Joseph M. Salvino, Adam P. Dicker, Karen E. Knudsen, Robert B. Den
Journal: Clinical Cancer Research
Clin Cancer Res (2018) 24 (6): 1402–1414.
https://doi.org/10.1158/1078-0432.CCR-17-2074
Published: 14 March 2018
View article titled, Therapeutic Challenge with a CDK 4/6 Inhibitor Induces an RB-Dependent SMAC-Mediated Apoptotic Response in Non–Small Cell Lung Cancer
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Includes: Supplementary data
Journal Articles

TOP2A and EZH2 Provide Early Detection of an Aggressive Prostate Cancer Subgroup

David P. Labbé, Christopher J. Sweeney, Myles Brown, Phillip Galbo, Spencer Rosario, Kristine M. Wadosky, Sheng-Yu Ku, Martin Sjöström, Mohammed Alshalalfa, Nicholas Erho, Elai Davicioni, R. Jeffrey Karnes, Edward M. Schaeffer, Robert B. Jenkins, Robert B. Den, Ashley E. Ross, Michaela Bowden, Ying Huang, Kathryn P. Gray, Felix Y. Feng, Daniel E. Spratt, David W. Goodrich, Kevin H. Eng, Leigh Ellis
Journal: Clinical Cancer Research
Clin Cancer Res (2017) 23 (22): 7072–7083.
https://doi.org/10.1158/1078-0432.CCR-17-0413
Published: 14 November 2017
View article titled, TOP2A and EZH2 Provide Early Detection of an Aggressive Prostate Cancer Subgroup
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Includes: Supplementary data
Journal Articles

The Landscape of Prognostic Outlier Genes in High-Risk Prostate Cancer

Shuang G. Zhao, Joseph R. Evans, Vishal Kothari, Grace Sun, Ashley Larm, Victor Mondine, Edward M. Schaeffer, Ashley E. Ross, Eric A. Klein, Robert B. Den, Adam P. Dicker, R. Jeffrey Karnes, Nicholas Erho, Paul L. Nguyen, Elai Davicioni, Felix Y. Feng
Journal: Clinical Cancer Research
Clin Cancer Res (2016) 22 (7): 1777–1786.
https://doi.org/10.1158/1078-0432.CCR-15-1250
Published: 31 March 2016
View article titled, The Landscape of Prognostic Outlier Genes in High-Risk Prostate Cancer
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Includes: Supplementary data
Journal Articles

Novel Actions of Next-Generation Taxanes Benefit Advanced Stages of Prostate Cancer

Renée de Leeuw, Lisa D. Berman-Booty, Matthew J. Schiewer, Stephen J. Ciment, Robert B. Den, Adam P. Dicker, William K. Kelly, Edouard J. Trabulsi, Costas D. Lallas, Leonard G. Gomella, Karen E. Knudsen
Journal: Clinical Cancer Research
Clin Cancer Res (2015) 21 (4): 795–807.
https://doi.org/10.1158/1078-0432.CCR-14-1358
Published: 16 February 2015
View article titled, Novel Actions of Next-Generation Taxanes Benefit Advanced Stages of Prostate Cancer
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Includes: Supplementary data
Journal Articles

The Retinoblastoma Tumor Suppressor Modulates DNA Repair and Radioresponsiveness

Chellappagounder Thangavel, Ettickan Boopathi, Steve Ciment, Yi Liu, Raymond O' Neill, Ankur Sharma, Steve B. McMahon, Hestia Mellert, Sankar Addya, Adam Ertel, Ruth Birbe, Paolo Fortina, Adam P. Dicker, Karen E. Knudsen, Robert B. Den
Journal: Clinical Cancer Research
Clin Cancer Res (2014) 20 (21): 5468–5482.
https://doi.org/10.1158/1078-0432.CCR-14-0326
Published: 01 November 2014
View article titled, The Retinoblastoma Tumor Suppressor Modulates DNA Repair and Radioresponsiveness
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Includes: Supplementary data