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Robert A. Casero
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Journal Articles

Novel Oligoamine Analogues Inhibit Lysine-Specific Demethylase 1 and Induce Reexpression of Epigenetically Silenced Genes

Yi Huang, Tracy Murray Stewart, Yu Wu, Stephen B. Baylin, Laurence J. Marton, Brandy Perkins, Richard J. Jones, Patrick M. Woster, Robert A. Casero, Jr.
Journal: Clinical Cancer Research
Clin Cancer Res (2009) 15 (23): 7217–7228.
https://doi.org/10.1158/1078-0432.CCR-09-1293
Published: 30 November 2009
View article titled, Novel Oligoamine Analogues Inhibit Lysine-Specific Demethylase 1 and Induce Reexpression of Epigenetically Silenced Genes
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Includes: Supplementary data
Journal Articles

A Phase II Study of the Polyamine Analog N 1, N 11-Diethylnorspermine (DENSpm) Daily for Five Days Every 21 Days in Patients with Previously Treated Metastatic Breast Cancer

Antonio C. Wolff, Deborah K. Armstrong, John H. Fetting, M. Katherine Carducci, Carol D. Riley, John F. Bender, Robert A. Casero, Jr., Nancy E. Davidson
Journal: Clinical Cancer Research
Clin Cancer Res (2003) 9 (16): 5922–5928.
Published: 15 December 2003
View article titled, A Phase II Study of the Polyamine Analog <em>N</em> <sup>1</sup>, <em>N</em> <sup>11</sup>-Diethylnorspermine (DENSpm) Daily for Five Days Every 21 Days in Patients with Previously Treated Metastatic Breast Cancer
Open the PDF for A Phase II Study of the Polyamine Analog <em>N</em> <sup>1</sup>, <em>N</em> <sup>11</sup>-Diethylnorspermine (DENSpm) Daily for Five Days Every 21 Days in Patients with Previously Treated Metastatic Breast Cancer in another window
Journal Articles

A Novel Polyamine Analog Inhibits Growth and Induces Apoptosis in Human Breast Cancer Cells

Yi Huang, Erin R. Hager, Dawn L. Phillips, Valerie R. Dunn, Amy Hacker, Benjamin Frydman, John A. Kink, Aldonia L. Valasinas, Venodhar K. Reddy, Laurence J. Marton, Robert A. Casero, Jr., Nancy E. Davidson
Journal: Clinical Cancer Research
Clin Cancer Res (2003) 9 (7): 2769–2777.
Published: 01 July 2003
View article titled, A Novel Polyamine Analog Inhibits Growth and Induces Apoptosis in Human Breast Cancer Cells
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Journal Articles

Growth Status Significantly Affects the Response of Human Lung Cancer Cells to Antitumor Polyamine-Analogue Exposure

Diane L. Carlisle, Wendy L. Devereux, Amy Hacker, Patrick M. Woster, Robert A. Casero, Jr.
Journal: Clinical Cancer Research
Clin Cancer Res (2002) 8 (8): 2684–2689.
Published: 01 August 2002
View article titled, Growth Status Significantly Affects the Response of Human Lung Cancer Cells to Antitumor Polyamine-Analogue Exposure
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Journal Articles

Detoxification of the Polyamine Analogue N 1-Ethyl- N 11-[(cycloheptyl)methy]-4,8-diazaundecane (CHENSpm) by Polyamine Oxidase

Kathryn R. Lawson, Sarah Marek, Jennifer A. Linehan, Patrick M. Woster, Robert A. Casero, Jr., Claire M. Payne, Eugene W. Gerner
Journal: Clinical Cancer Research
Clin Cancer Res (2002) 8 (5): 1241–1247.
Published: 01 May 2002
View article titled, Detoxification of the Polyamine Analogue <em>N</em> <sup>1</sup>-Ethyl- <em>N</em> <sup>11</sup>-[(cycloheptyl)methy]-4,8-diazaundecane (CHENSpm) by Polyamine Oxidase
Open the PDF for Detoxification of the Polyamine Analogue <em>N</em> <sup>1</sup>-Ethyl- <em>N</em> <sup>11</sup>-[(cycloheptyl)methy]-4,8-diazaundecane (CHENSpm) by Polyamine Oxidase in another window
Journal Articles

Phase I Study of N 1, N 11-Diethylnorspermine in Patients with Non-Small Cell Lung Cancer

Hillary A. Hahm, David S. Ettinger, Kathy Bowling, Beth Hoker, Tian Ling Chen, Yelena Zabelina, Robert A. Casero, Jr.
Journal: Clinical Cancer Research
Clin Cancer Res (2002) 8 (3): 684–690.
Published: 01 March 2002
View article titled, Phase I Study of <em>N</em> <sup>1</sup>, <em>N</em> <sup>11</sup>-Diethylnorspermine in Patients with Non-Small Cell Lung Cancer
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Journal Articles

Combination of Standard Cytotoxic Agents with Polyamine Analogues in the Treatment of Breast Cancer Cell Lines

Hillary A. Hahm, Valerie R. Dunn, Kimberly A. Butash, Wendy L. Deveraux, Patrick M. Woster, Robert A. Casero, Jr., Nancy E. Davidson
Journal: Clinical Cancer Research
Clin Cancer Res (2001) 7 (2): 391–399.
Published: 01 February 2001
View article titled, Combination of Standard Cytotoxic Agents with Polyamine Analogues in the Treatment of Breast Cancer Cell Lines
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Journal Articles

Reactive Oxygen Species Are Critical for the Growth and Differentiation of Medullary Thyroid Carcinoma Cells

Hyo Chol Ha, Arunthathi Thiagalingam, Barry D. Nelkin, Robert A. Casero, Jr.
Journal: Clinical Cancer Research
Clin Cancer Res (2000) 6 (9): 3783–3787.
Published: 01 September 2000
View article titled, Reactive Oxygen Species Are Critical for the Growth and Differentiation of Medullary Thyroid Carcinoma Cells
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Journal Articles

Effects of the Polyamine Analogues N1-Ethyl-N11-((cyclopropyl)methyl)-4,8-diazaundecane and N1-Ethyl-N11-((cycloheptyl)methyl)-4,8- diazaundecane in Human Prostate Cancer Cells

Diane E. McCloskey, Patrick M. Woster, Robert A. Casero, Jr., Nancy E. Davidson
Journal: Clinical Cancer Research
Clin Cancer Res (2000) 6 (1): 17–23.
Published: 01 January 2000
View article titled, Effects of the Polyamine Analogues <em>N</em><sup>1</sup>-Ethyl-<em>N</em><sup>11</sup>-((cyclopropyl)methyl)-4,8-diazaundecane and <em>N</em><sup>1</sup>-Ethyl-<em>N</em><sup>11</sup>-((cycloheptyl)methyl)-4,8- diazaundecane in Human Prostate Cancer Cells
Open the PDF for Effects of the Polyamine Analogues <em>N</em><sup>1</sup>-Ethyl-<em>N</em><sup>11</sup>-((cyclopropyl)methyl)-4,8-diazaundecane and <em>N</em><sup>1</sup>-Ethyl-<em>N</em><sup>11</sup>-((cycloheptyl)methyl)-4,8- diazaundecane in Human Prostate Cancer Cells in another window
Journal Articles

The Induction of Spermidine/Spermine N1-Acetyltransferase (SSAT) Is a Common Event in the Response of Human Primary Non-Small Cell Lung Carcinomas to Exposure to the New Antitumor Polyamine Analogue N1,N11-Bis(ethyl)norspermine1

Edward W. Gabrielson, Anthony E. Pegg, Robert A. Casero, Jr.
Journal: Clinical Cancer Research
Clin Cancer Res (1999) 5 (7): 1638–1641.
Published: 01 July 1999
View article titled, The Induction of Spermidine/Spermine <em>N</em><sup>1</sup>-Acetyltransferase (SSAT) Is a Common Event in the Response of Human Primary Non-Small Cell Lung Carcinomas to Exposure to the New Antitumor Polyamine Analogue <em>N</em><sup>1</sup>,<em>N</em><sup>11</sup>-Bis(ethyl)norspermine<sup>1</sup>
Open the PDF for The Induction of Spermidine/Spermine <em>N</em><sup>1</sup>-Acetyltransferase (SSAT) Is a Common Event in the Response of Human Primary Non-Small Cell Lung Carcinomas to Exposure to the New Antitumor Polyamine Analogue <em>N</em><sup>1</sup>,<em>N</em><sup>11</sup>-Bis(ethyl)norspermine<sup>1</sup> in another window