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Journal Articles

The Immune-Related 27-Gene Signature DetermaIO Predicts Response to Neoadjuvant Atezolizumab plus Chemotherapy in Triple-Negative Breast Cancer

Matteo Dugo, Chiun-Sheng Huang, Daniel Egle, Begoña Bermejo, Claudio Zamagni, Robert S. Seitz, Tyler J. Nielsen, Marc Thill, Antonio Antón-Torres, Stefania Russo, Eva Maria Ciruelos, Brock L. Schweitzer, Douglas T. Ross, Barbara Galbardi, Richard Greil, Vladimir Semiglazov, Balázs Gyorffy, Marco Colleoni, Catherine M. Kelly, Gabriella Mariani, Lucia Del Mastro, Olivia Blasi, Maurizio Callari, Lajos Pusztai, Pinuccia Valagussa, Giuseppe Viale, Luca Gianni, Giampaolo Bianchini
Journal: Clinical Cancer Research
Clin Cancer Res (2024) 30 (21): 4900–4909.
https://doi.org/10.1158/1078-0432.CCR-24-0149
Published: 01 November 2024
View article titled, The Immune-Related 27-Gene Signature DetermaIO Predicts Response to Neoadjuvant Atezolizumab plus Chemotherapy in Triple-Negative Breast Cancer
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Includes: Supplementary data
Journal Articles

A Phase I Study of Acapatamab, a Half-life Extended, PSMA-Targeting Bispecific T-cell Engager for Metastatic Castration-Resistant Prostate Cancer

Tanya Dorff, Lisa G. Horvath, Karen Autio, Alice Bernard-Tessier, Matthew B. Rettig, Jean-Pascal Machiels, Mehmet A. Bilen, Martijn P. Lolkema, Nabil Adra, Sylvie Rottey, Richard Greil, Nobuaki Matsubara, Daniel S.W. Tan, Alvin Wong, Hiroji Uemura, Charlotte Lemech, Johannes Meran, Youfei Yu, Mukul Minocha, Mason McComb, Hweixian Leong Penny, Vinita Gupta, Xuguang Hu, Gabor Jurida, Hosein Kouros-Mehr, Margit M. Janát-Amsbury, Tobias Eggert, Ben Tran
Journal: Clinical Cancer Research
Clin Cancer Res (2024) 30 (8): 1488–1500.
https://doi.org/10.1158/1078-0432.CCR-23-2978
Published: 15 April 2024
View article titled, A Phase I Study of Acapatamab, a Half-life Extended, PSMA-Targeting Bispecific T-cell Engager for Metastatic Castration-Resistant Prostate Cancer
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Includes: Supplementary data
Journal Articles

Estrogen Receptor Alpha Gene Amplification Is an Independent Predictor of Long-Term Outcome in Postmenopausal Patients with Endocrine-Responsive Early Breast Cancer

Christian F. Singer, for the ABCSG, Frederik Holst, Stefan Steurer, Eike C. Burandt, Sigurd F. Lax, Raimund Jakesz, Margaretha Rudas, Herbert Stöger, Richard Greil, for the ABCSG, Guido Sauter, Martin Filipits, for the ABCSG, Ronald Simon, Michael Gnant, for the ABCSG
Journal: Clinical Cancer Research
Clin Cancer Res (2022) 28 (18): 4112–4120.
https://doi.org/10.1158/1078-0432.CCR-21-4328
Published: 15 September 2022
View article titled, Estrogen Receptor Alpha Gene Amplification Is an Independent Predictor of Long-Term Outcome in Postmenopausal Patients with Endocrine-Responsive Early Breast Cancer
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Journal Articles

Improved Efficacy of Tafasitamab plus Lenalidomide versus Systemic Therapies for Relapsed/Refractory DLBCL: RE-MIND2, an Observational Retrospective Matched Cohort Study

Grzegorz S. Nowakowski, Dok Hyun Yoon, Anthea Peters, Patrizia Mondello, Erel Joffe, Isabelle Fleury, Richard Greil, Matthew Ku, Reinhard Marks, Kibum Kim, Pier Luigi Zinzani, Judith Trotman, Dan Huang, Eva E. Waltl, Mark Winderlich, Nuwan C. Kurukulasuriya, Sumeet Ambarkhane, Georg Hess, Gilles Salles
Journal: Clinical Cancer Research
Clin Cancer Res (2022) 28 (18): 4003–4017.
https://doi.org/10.1158/1078-0432.CCR-21-3648
Published: 15 September 2022
View article titled, Improved Efficacy of Tafasitamab plus Lenalidomide versus Systemic Therapies for Relapsed/Refractory DLBCL: RE-MIND2, an Observational Retrospective Matched Cohort Study
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Includes: Supplementary data
Journal Articles

A Randomized Phase II Study of Anti-CSF1 Monoclonal Antibody Lacnotuzumab (MCS110) Combined with Gemcitabine and Carboplatin in Advanced Triple-Negative Breast Cancer

Sherko Kuemmel, Mario Campone, Delphine Loirat, Rafael Lopez Lopez, J. Thaddeus Beck, Michelino De Laurentiis, Seock-Ah Im, Sung-Bae Kim, Ava Kwong, Guenther G. Steger, Esther Zamora Adelantado, Francois P. Duhoux, Richard Greil, Irene Kuter, Yen-Shen Lu, Ariadna Tibau, Mustafa Özgüroğlu, Christian W. Scholz, Christian F. Singer, Estela Vega, Pauline Wimberger, Claudio Zamagni, Xuan-Mai Couillebault, Liqiong Fan, Nelson Guerreiro, Jennifer Mataraza, Janna Sand-Dejmek, Arlene Chan
Journal: Clinical Cancer Research
Clin Cancer Res (2022) 28 (1): 106–115.
https://doi.org/10.1158/1078-0432.CCR-20-3955
Published: 05 January 2022
View article titled, A Randomized Phase II Study of Anti-CSF1 Monoclonal Antibody Lacnotuzumab (MCS110) Combined with Gemcitabine and Carboplatin in Advanced Triple-Negative Breast Cancer
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Includes: Supplementary data
Journal Articles

The OncoMasTR Test Predicts Distant Recurrence in Estrogen Receptor–Positive, HER2-Negative Early-Stage Breast Cancer: A Validation Study in ABCSG Trial 8

Martin Filipits, Margaretha Rudas, Verena Kainz, Christian F. Singer, Florian Fitzal, Zsuzsanna Bago-Horvath, Richard Greil, Marija Balic, Peter Regitnig, Stefan Halper, Wolfgang Hulla, Daniel Egle, Stephen Barron, Tony Loughman, Des O'Leary, William M. Gallagher, Dominik Hlauschek, Michael Gnant, Peter Dubsky
Journal: Clinical Cancer Research
Clin Cancer Res (2021) 27 (21): 5931–5938.
https://doi.org/10.1158/1078-0432.CCR-21-1023
Published: 01 November 2021
View article titled, The OncoMasTR Test Predicts Distant Recurrence in Estrogen Receptor–Positive, HER2-Negative Early-Stage Breast Cancer: A Validation Study in ABCSG Trial 8
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Includes: Supplementary data
Journal Articles

Predictive Value of Molecular Subtypes in Premenopausal Women with Hormone Receptor–positive Early Breast Cancer: Results from the ABCSG Trial 5

Zsuzsanna Bago-Horvath, Margaretha Rudas, Christian F. Singer, Richard Greil, Marija Balic, Sigurd F. Lax, Werner Kwasny, Wolfgang Hulla, Michael Gnant, Martin Filipits
Journal: Clinical Cancer Research
Clin Cancer Res (2020) 26 (21): 5682–5688.
https://doi.org/10.1158/1078-0432.CCR-20-0673
Published: 02 November 2020
View article titled, Predictive Value of Molecular Subtypes in Premenopausal Women with Hormone Receptor–positive Early Breast Cancer: Results from the ABCSG Trial 5
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Journal Articles

Prognostic Value of EndoPredict in Women with Hormone Receptor–Positive, HER2-Negative Invasive Lobular Breast Cancer

Ivana Sestak, Martin Filipits, Richard Buus, Margaretha Rudas, Marija Balic, Michael Knauer, Ralf Kronenwett, Florian Fitzal, Jack Cuzick, Michael Gnant, Richard Greil, Mitch Dowsett, Peter Dubsky
Journal: Clinical Cancer Research
Clin Cancer Res (2020) 26 (17): 4682–4687.
https://doi.org/10.1158/1078-0432.CCR-20-0260
Published: 01 September 2020
View article titled, Prognostic Value of EndoPredict in Women with Hormone Receptor–Positive, HER2-Negative Invasive Lobular Breast Cancer
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Journal Articles

Prediction of Distant Recurrence Using EndoPredict Among Women with ER+, HER2− Node-Positive and Node-Negative Breast Cancer Treated with Endocrine Therapy Only

Martin Filipits, Peter Dubsky, Margaretha Rudas, Richard Greil, Marija Balic, Zsuzsanna Bago-Horvath, Christian F. Singer, Dominik Hlauschek, Krystal Brown, Ryan Bernhisel, Ralf Kronenwett, Johnathan M. Lancaster, Florian Fitzal, Michael Gnant
Journal: Clinical Cancer Research
Series: Author Choice
Clin Cancer Res (2019) 25 (13): 3865–3872.
https://doi.org/10.1158/1078-0432.CCR-19-0376
Published: 01 July 2019
View article titled, Prediction of Distant Recurrence Using EndoPredict Among Women with ER<sup>+</sup>, HER2<sup>−</sup> Node-Positive and Node-Negative Breast Cancer Treated with Endocrine Therapy Only
Open the PDF for Prediction of Distant Recurrence Using EndoPredict Among Women with ER<sup>+</sup>, HER2<sup>−</sup> Node-Positive and Node-Negative Breast Cancer Treated with Endocrine Therapy Only in another window
Includes: Supplementary data
Journal Articles

BIRC3 Expression Predicts CLL Progression and Defines Treatment Sensitivity via Enhanced NF-κB Nuclear Translocation

Daniela Asslaber, Nathalie Wacht, Michael Leisch, Yuan Qi, Nicole Maeding, Clemens Hufnagl, Bettina Jansko, Nadja Zaborsky, Andreas Villunger, Tanja N. Hartmann, Richard Greil, Alexander Egle
Journal: Clinical Cancer Research
Series: Author Choice
Clin Cancer Res (2019) 25 (6): 1901–1912.
https://doi.org/10.1158/1078-0432.CCR-18-1548
Published: 15 March 2019
View article titled, BIRC3 Expression Predicts CLL Progression and Defines Treatment Sensitivity via Enhanced NF-κB Nuclear Translocation
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Includes: Supplementary data
Journal Articles

The single nucleotide polymorphism MDM2-SNP309 predicts for sensitivity of B-CLL cells to the non-genotoxic activator of the p53 pathway Nutlin-3a

Inge Tinhofer, Irina Seyfried, Markus Stocher, Sebastian Hofbauer, Peter Daniel, Richard Greil
Journal: Clinical Cancer Research
Clin Cancer Res (2008) 14 (15_Supplement): B27.
Published: 15 August 2014
View article titled, The single nucleotide polymorphism MDM2-SNP309 predicts for sensitivity of B-CLL cells to the non-genotoxic activator of the p53 pathway Nutlin-3a
Journal Articles

The PAM50 Risk-of-Recurrence Score Predicts Risk for Late Distant Recurrence after Endocrine Therapy in Postmenopausal Women with Endocrine-Responsive Early Breast Cancer

Martin Filipits, Torsten O. Nielsen, Margaretha Rudas, Richard Greil, Herbert Stöger, Raimund Jakesz, Zsuzsanna Bago-Horvath, Otto Dietze, Peter Regitnig, Christine Gruber-Rossipal, Elisabeth Müller-Holzner, Christian F. Singer, Brigitte Mlineritsch, Peter Dubsky, Thomas Bauernhofer, Michael Hubalek, Michael Knauer, Harald Trapl, Christian Fesl, Carl Schaper, Sean Ferree, Shuzhen Liu, J. Wayne Cowens, Michael Gnant, for the Austrian Breast and Colorectal Cancer Study Group
Journal: Clinical Cancer Research
Clin Cancer Res (2014) 20 (5): 1298–1305.
https://doi.org/10.1158/1078-0432.CCR-13-1845
Published: 02 March 2014
View article titled, The PAM50 Risk-of-Recurrence Score Predicts Risk for Late Distant Recurrence after Endocrine Therapy in Postmenopausal Women with Endocrine-Responsive Early Breast Cancer
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Includes: Supplementary data
Journal Articles

CYP2D6 Metabolism and Patient Outcome in the Austrian Breast and Colorectal Cancer Study Group Trial (ABCSG) 8

Matthew P. Goetz, Vera J. Suman, Tanya L. Hoskin, Michael Gnant, Martin Filipits, Stephanie L. Safgren, Mary Kuffel, Raimund Jakesz, Margaretha Rudas, Richard Greil, Otto Dietze, Alois Lang, Felix Offner, Carol A. Reynolds, Richard M. Weinshilboum, Matthew M. Ames, James N. Ingle
Journal: Clinical Cancer Research
Clin Cancer Res (2013) 19 (2): 500–507.
https://doi.org/10.1158/1078-0432.CCR-12-2153
Published: 16 January 2013
View article titled, CYP2D6 Metabolism and Patient Outcome in the Austrian Breast and Colorectal Cancer Study Group Trial (ABCSG) 8
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Journal Articles

Adjuvant Sequencing of Tamoxifen and Anastrozole Is Superior to Tamoxifen Alone in Postmenopausal Women with Low Proliferating Breast Cancer

Zsuzsanna Bago-Horvath, Margaretha Rudas, Peter Dubsky, Raimund Jakesz, Christian F. Singer, Ralf Kemmerling, Richard Greil, Andrea Jelen, Gerhard Böhm, Zerina Jasarevic, Anton Haid, Christine Gruber, Sabine Pöstlberger, Martin Filipits, Michael Gnant
Journal: Clinical Cancer Research
Clin Cancer Res (2011) 17 (24): 7828–7834.
https://doi.org/10.1158/1078-0432.CCR-11-1846
Published: 18 December 2011
View article titled, Adjuvant Sequencing of Tamoxifen and Anastrozole Is Superior to Tamoxifen Alone in Postmenopausal Women with Low Proliferating Breast Cancer
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Journal Articles

A New Molecular Predictor of Distant Recurrence in ER-Positive, HER2-Negative Breast Cancer Adds Independent Information to Conventional Clinical Risk Factors

Martin Filipits, Margaretha Rudas, Raimund Jakesz, Peter Dubsky, Florian Fitzal, Christian F. Singer, Otto Dietze, Richard Greil, Andrea Jelen, Paul Sevelda, Christa Freibauer, Volkmar Müller, Fritz Jänicke, Marcus Schmidt, Heinz Kölbl, Achim Rody, Manfred Kaufmann, Werner Schroth, Hiltrud Brauch, Matthias Schwab, Peter Fritz, Karsten E. Weber, Inke S. Feder, Guido Hennig, Ralf Kronenwett, Mathias Gehrmann, Michael Gnant
Journal: Clinical Cancer Research
Clin Cancer Res (2011) 17 (18): 6012–6020.
https://doi.org/10.1158/1078-0432.CCR-11-0926
Published: 14 September 2011
View article titled, A New Molecular Predictor of Distant Recurrence in ER-Positive, HER2-Negative Breast Cancer Adds Independent Information to Conventional Clinical Risk Factors
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Includes: Supplementary data
Journal Articles

Low p27 Expression Predicts Early Relapse and Death in Postmenopausal Hormone Receptor–Positive Breast Cancer Patients Receiving Adjuvant Tamoxifen Therapy

Martin Filipits, Margaretha Rudas, Harald Heinzl, Raimund Jakesz, Ernst Kubista, Sigurd Lax, Walter Schippinger, Otto Dietze, Richard Greil, Wolfgang Stiglbauer, Werner Kwasny, Alexander Nader, Michael Stierer, Michael F.X. Gnant, for the Austrian Breast and Colorectal Cancer Study Group
Journal: Clinical Cancer Research
Clin Cancer Res (2009) 15 (18): 5888–5894.
https://doi.org/10.1158/1078-0432.CCR-09-0728
Published: 14 September 2009
View article titled, Low p27 Expression Predicts Early Relapse and Death in Postmenopausal Hormone Receptor–Positive Breast Cancer Patients Receiving Adjuvant Tamoxifen Therapy
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Journal Articles

Multicenter Phase II Study of Lapatinib in Patients with Brain Metastases from HER2-Positive Breast Cancer

Nancy U. Lin, Véronique Diéras, Devchand Paul, Dominique Lossignol, Christos Christodoulou, Hans-Joachim Stemmler, Henri Roché, Minetta C. Liu, Richard Greil, Eva Ciruelos, Sibylle Loibl, Stefania Gori, Andrew Wardley, Denise Yardley, Adam Brufsky, Joanne L. Blum, Stephen D. Rubin, Bernie Dharan, Klaudia Steplewski, Denise Zembryki, Cristina Oliva, Debasish Roychowdhury, Paolo Paoletti, Eric P. Winer
Journal: Clinical Cancer Research
Clin Cancer Res (2009) 15 (4): 1452–1459.
https://doi.org/10.1158/1078-0432.CCR-08-1080
Published: 19 February 2009
View article titled, Multicenter Phase II Study of Lapatinib in Patients with Brain Metastases from HER2-Positive Breast Cancer
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Includes: Supplementary data
Journal Articles

Anemia Is a Significant Prognostic Factor in Local Relapse-Free Survival of Premenopausal Primary Breast Cancer Patients Receiving Adjuvant Cyclophosphamide/Methotrexate/5-Fluorouracil Chemotherapy

Peter Dubsky, Paul Sevelda, Raimund Jakesz, Hubert Hausmaninger, Hellmut Samonigg, Michael Seifert, Ursula Denison, Brigitte Mlineritsch, Günther Steger, Werner Kwasny, Herbert Stöger, Rupert Bartsch, Michael Stierer, Susanne Taucher, Michael Fridrik, Walter Schippinger, Richard Greil, Richard Pötter, Michael Gnant, for the Austrian Breast and Colorectal Cancer Study Group
Journal: Clinical Cancer Research
Clin Cancer Res (2008) 14 (7): 2082–2087.
https://doi.org/10.1158/1078-0432.CCR-07-2068
Published: 01 April 2008
View article titled, Anemia Is a Significant Prognostic Factor in Local Relapse-Free Survival of Premenopausal Primary Breast Cancer Patients Receiving Adjuvant Cyclophosphamide/Methotrexate/5-Fluorouracil Chemotherapy
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Journal Articles

Cyclin D1 Expression in Breast Cancer Patients Receiving Adjuvant Tamoxifen-Based Therapy

Margaretha Rudas, Martina Lehnert, Anh Huynh, Raimund Jakesz, Christian Singer, Sigurd Lax, Walter Schippinger, Otto Dietze, Richard Greil, Wolfgang Stiglbauer, Werner Kwasny, Renate Grill, Michael Stierer, Michael F.X. Gnant, Martin Filipits, for the Austrian Breast and Colorectal Cancer Study Group
Journal: Clinical Cancer Research
Clin Cancer Res (2008) 14 (6): 1767–1774.
https://doi.org/10.1158/1078-0432.CCR-07-4122
Published: 17 March 2008
View article titled, Cyclin D1 Expression in Breast Cancer Patients Receiving Adjuvant Tamoxifen-Based Therapy
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Journal Articles

Up-Regulation of Functional Chemokine Receptor CCR3 in Human Renal Cell Carcinoma

Karin Jöhrer, Claudia Zelle-Rieser, Alexander Perathoner, Patrizia Moser, Martina Hager, Reinhold Ramoner, Hubert Gander, Lorenz Höltl, Georg Bartsch, Richard Greil, Martin Thurnher
Journal: Clinical Cancer Research
Clin Cancer Res (2005) 11 (7): 2459–2465.
https://doi.org/10.1158/1078-0432.CCR-04-0405
Published: 06 April 2005
View article titled, Up-Regulation of Functional Chemokine Receptor CCR3 in Human Renal Cell Carcinoma
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