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Rajyalakshmi Luthra
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Journal Articles

Multi-omics Analysis Reveals Immune Features Associated with Immunotherapy Benefit in Patients with Squamous Cell Lung Cancer from Phase III Lung-MAP S1400I Trial

Edwin Roger Parra, Jiexin Zhang, Dzifa Yawa Duose, Edgar Gonzalez-Kozlova, Mary W. Redman, Hong Chen, Ganiraju C. Manyam, Gayatri Kumar, Jianhua Zhang, Xingzhi Song, Rossana Lazcano, Mario L. Marques-Piubelli, Caddie Laberiano-Fernandez, Frank Rojas, Baili Zhang, Len Taing, Aashna Jhaveri, Jacob Geisberg, Jennifer Altreuter, Franziska Michor, James Provencher, Joyce Yu, Ethan Cerami, Radim Moravec, Kasthuri Kannan, Rajyalakshmi Luthra, Gheath Alatrash, Hsin-Hui Huang, Hui Xie, Manishkumar Patel, Kai Nie, Jocelyn Harris, Kimberly Argueta, James Lindsay, Roshni Biswas, Stephen Van Nostrand, Seunghee Kim-Schulze, Jhanelle E. Gray, Roy S. Herbst, Ignacio I. Wistuba, Scott Gettinger, Karen Kelly, Lyudmila Bazhenova, Sacha Gnjatic, J. Jack Lee, Jianjun Zhang, Cara Haymaker
Journal: Clinical Cancer Research
Clin Cancer Res (2024) 30 (8): 1655–1668.
https://doi.org/10.1158/1078-0432.CCR-23-0251
Published: 15 April 2024
View articletitled, Multi-omics Analysis Reveals Immune Features Associated with Immunotherapy Benefit in Patients with Squamous Cell Lung Cancer from Phase III Lung-MAP S1400I Trial
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Includes: Supplementary data
Journal Articles

Development and Validation of a Gene Signature Classifier for Consensus Molecular Subtyping of Colorectal Carcinoma in a CLIA-Certified Setting

Jeffrey S. Morris, Rajyalakshmi Luthra, Yusha Liu, Dzifa Y. Duose, Wonyul Lee, Neelima G. Reddy, Justin Windham, Huiqin Chen, Zhimin Tong, Baili Zhang, Wei Wei, Manyam Ganiraju, Bradley M. Broom, Hector A. Alvarez, Alicia Mejia, Omkara Veeranki, Mark J. Routbort, Van K. Morris, Michael J. Overman, David Menter, Riham Katkhuda, Ignacio I. Wistuba, Jennifer S. Davis, Scott Kopetz, Dipen M. Maru
Journal: Clinical Cancer Research
Series: Author Choice
Clin Cancer Res (2021) 27 (1): 120–130.
https://doi.org/10.1158/1078-0432.CCR-20-2403
Published: 04 January 2021
View articletitled, Development and Validation of a Gene Signature Classifier for Consensus Molecular Subtyping of Colorectal Carcinoma in a CLIA-Certified Setting
Open the PDF for Development and Validation of a Gene Signature Classifier for Consensus Molecular Subtyping of Colorectal Carcinoma in a CLIA-Certified Setting in another window
Includes: Supplementary data
Journal Articles

Classifying Colorectal Cancer by Tumor Location Rather than Sidedness Highlights a Continuum in Mutation Profiles and Consensus Molecular Subtypes

Jonathan M. Loree, Allan A.L. Pereira, Michael Lam, Alexandra N. Willauer, Kanwal Raghav, Arvind Dasari, Van. K Morris, Shailesh Advani, David G. Menter, Cathy Eng, Kenna Shaw, Russell Broaddus, Mark J. Routbort, Yusha Liu, Jeffrey S. Morris, Rajyalakshmi Luthra, Funda Meric-Bernstam, Michael J. Overman, Dipen Maru, Scott Kopetz
Journal: Clinical Cancer Research
Clin Cancer Res (2018) 24 (5): 1062–1072.
https://doi.org/10.1158/1078-0432.CCR-17-2484
Published: 28 February 2018
View articletitled, Classifying Colorectal Cancer by Tumor Location Rather than Sidedness Highlights a Continuum in Mutation Profiles and Consensus Molecular Subtypes
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Includes: Supplementary data
Journal Articles

Development and Validation of an Ultradeep Next-Generation Sequencing Assay for Testing of Plasma Cell-Free DNA from Patients with Advanced Cancer

Filip Janku, Shile Zhang, Jill Waters, Li Liu, Helen J. Huang, Vivek Subbiah, David S. Hong, Daniel D. Karp, Siqing Fu, Xuyu Cai, Nishma M. Ramzanali, Kiran Madwani, Goran Cabrilo, Debra L. Andrews, Yue Zhao, Milind Javle, E. Scott Kopetz, Rajyalakshmi Luthra, Hyunsung J. Kim, Sante Gnerre, Ravi Vijaya Satya, Han-Yu Chuang, Kristina M. Kruglyak, Jonathan Toung, Chen Zhao, Richard Shen, John V. Heymach, Funda Meric-Bernstam, Gordon B. Mills, Jian-Bing Fan, Neeraj S. Salathia
Journal: Clinical Cancer Research
Clin Cancer Res (2017) 23 (18): 5648–5656.
https://doi.org/10.1158/1078-0432.CCR-17-0291
Published: 14 September 2017
View articletitled, Development and Validation of an Ultradeep Next-Generation Sequencing Assay for Testing of Plasma Cell-Free DNA from Patients with Advanced Cancer
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Includes: Supplementary data
Journal Articles

Mutation-Enrichment Next-Generation Sequencing for Quantitative Detection of KRAS Mutations in Urine Cell-Free DNA from Patients with Advanced Cancers

Takeo Fujii, Afsaneh Barzi, Andrea Sartore-Bianchi, Andrea Cassingena, Giulia Siravegna, Daniel D. Karp, Sarina A. Piha-Paul, Vivek Subbiah, Apostolia M. Tsimberidou, Helen J. Huang, Silvio Veronese, Federica Di Nicolantonio, Sandeep Pingle, Cecile Rose T. Vibat, Saege Hancock, David Berz, Vladislava O. Melnikova, Mark G. Erlander, Rajyalakshmi Luthra, E. Scott Kopetz, Funda Meric-Bernstam, Salvatore Siena, Heinz-Josef Lenz, Alberto Bardelli, Filip Janku
Journal: Clinical Cancer Research
Clin Cancer Res (2017) 23 (14): 3657–3666.
https://doi.org/10.1158/1078-0432.CCR-16-2592
Published: 13 July 2017
View articletitled, Mutation-Enrichment Next-Generation Sequencing for Quantitative Detection of KRAS Mutations in Urine Cell-Free DNA from Patients with Advanced Cancers
Open the PDF for Mutation-Enrichment Next-Generation Sequencing for Quantitative Detection of KRAS Mutations in Urine Cell-Free DNA from Patients with Advanced Cancers in another window
Includes: Supplementary data
Journal Articles

Hotspot Mutation Panel Testing Reveals Clonal Evolution in a Study of 265 Paired Primary and Metastatic Tumors

Rashmi S. Goswami, Keyur P. Patel, Rajesh R. Singh, Funda Meric-Bernstam, E. Scott Kopetz, Vivek Subbiah, Ricardo H. Alvarez, Michael A. Davies, Kausar J. Jabbar, Sinchita Roy-Chowdhuri, Alexander J. Lazar, L. Jeffrey Medeiros, Russell R. Broaddus, Rajyalakshmi Luthra, Mark J. Routbort
Journal: Clinical Cancer Research
Clin Cancer Res (2015) 21 (11): 2644–2651.
https://doi.org/10.1158/1078-0432.CCR-14-2391
Published: 31 May 2015
View articletitled, Hotspot Mutation Panel Testing Reveals Clonal Evolution in a Study of 265 Paired Primary and Metastatic Tumors
Open the PDF for Hotspot Mutation Panel Testing Reveals Clonal Evolution in a Study of 265 Paired Primary and Metastatic Tumors in another window
Includes: Supplementary data
Journal Articles

Personalized Medicine in a Phase I Clinical Trials Program: The MD Anderson Cancer Center Initiative

Apostolia-Maria Tsimberidou, Nancy G. Iskander, David S. Hong, Jennifer J. Wheler, Gerald S. Falchook, Siqing Fu, Sarina Piha-Paul, Aung Naing, Filip Janku, Rajyalakshmi Luthra, Yang Ye, Sijin Wen, Donald Berry, Razelle Kurzrock
Journal: Clinical Cancer Research
Clin Cancer Res (2012) 18 (22): 6373–6383.
https://doi.org/10.1158/1078-0432.CCR-12-1627
Published: 14 November 2012
View articletitled, Personalized Medicine in a Phase I Clinical Trials Program: The MD Anderson Cancer Center Initiative
Open the PDF for Personalized Medicine in a Phase I Clinical Trials Program: The MD Anderson Cancer Center Initiative in another window
Includes: Supplementary data
Journal Articles

Complex Patterns of Altered MicroRNA Expression during the Adenoma-Adenocarcinoma Sequence for Microsatellite-Stable Colorectal Cancer

Angela N. Bartley, Hui Yao, Bedia A. Barkoh, Cristina Ivan, Bal M. Mishra, Asif Rashid, George A. Calin, Rajyalakshmi Luthra, Stanley R. Hamilton
Journal: Clinical Cancer Research
Clin Cancer Res (2011) 17 (23): 7283–7293.
https://doi.org/10.1158/1078-0432.CCR-11-1452
Published: 30 November 2011
View articletitled, Complex Patterns of Altered MicroRNA Expression during the Adenoma-Adenocarcinoma Sequence for Microsatellite-Stable Colorectal Cancer
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Includes: Supplementary data
Journal Articles

Decreased Expression of Gene Cluster at Chromosome 1q21 Defines Molecular Subgroups of Chemoradiotherapy Response in Esophageal Cancers

Madan G. Luthra, Jaffer A. Ajani, Julie Izzo, Joe Ensor, Tsung-Teh Wu, Asif Rashid, Li Zhang, Alexandria Phan, Norio Fukami, Rajyalakshmi Luthra
Journal: Clinical Cancer Research
Clin Cancer Res (2007) 13 (3): 912–919.
https://doi.org/10.1158/1078-0432.CCR-06-1577
Published: 08 February 2007
View articletitled, Decreased Expression of Gene Cluster at Chromosome 1q21 Defines Molecular Subgroups of Chemoradiotherapy Response in Esophageal Cancers
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Journal Articles

Molecular Responses in Patients with Chronic Myelogenous Leukemia in Chronic Phase Treated with Imatinib Mesylate

Jorge Cortes, Moshe Talpaz, Susan O'Brien, Dan Jones, Rajyalakshmi Luthra, Jenny Shan, Francis Giles, Stefan Faderl, Srdan Verstovsek, Guillermo Garcia-Manero, Mary B. Rios, Hagop Kantarjian
Journal: Clinical Cancer Research
Clin Cancer Res (2005) 11 (9): 3425–3432.
https://doi.org/10.1158/1078-0432.CCR-04-2139
Published: 02 May 2005
View articletitled, Molecular Responses in Patients with Chronic Myelogenous Leukemia in Chronic Phase Treated with Imatinib Mesylate
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Journal Articles

Degree of CD25 Expression in T-Cell Lymphoma Is Dependent on Tissue Site: Implications for Targeted Therapy

Dan Jones, Sherif Ibrahim, Kaushali Patel, Rajyalakshmi Luthra, Madeleine Duvic, L. Jeffrey Medeiros
Journal: Clinical Cancer Research
Clin Cancer Res (2004) 10 (16): 5587–5594.
https://doi.org/10.1158/1078-0432.CCR-0721-03
Published: 24 August 2004
View articletitled, Degree of CD25 Expression in T-Cell Lymphoma Is Dependent on Tissue Site: Implications for Targeted Therapy
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Journal Articles

TabBO: A Model Reflecting Common Molecular Features of Androgen-independent Prostate Cancer

Nora M. Navone, Maria del C. Rodriguez-Vargas, William F. Benedict, Patricia Troncoso, Timothy J. McDonnell, Jaim-Hua Zhou, Rajyalakshmi Luthra, Christopher J. Logothetis
Journal: Clinical Cancer Research
Clin Cancer Res (2000) 6 (3): 1190–1197.
Published: 01 March 2000
View articletitled, TabBO: A Model Reflecting Common Molecular Features of Androgen-independent Prostate Cancer
Open the PDF for TabBO: A Model Reflecting Common Molecular Features of Androgen-independent Prostate Cancer in another window