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Rajiv Kumar
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Journal Articles

First-in-Human Study of AT13148, a Dual ROCK-AKT Inhibitor in Patients with Solid Tumors

Robert McLeod, Rajiv Kumar, Dionysis Papadatos-Pastos, Joaquin Mateo, Jessica S. Brown, Alvaro H. Ingles Garces, Ruth Ruddle, Shaun Decordova, Simone Jueliger, Roberta Ferraldeschi, Oscar Maiques, Victoria Sanz-Moreno, Paul Jones, Stephanie Traub, Gavin Halbert, Sarah Mellor, Karen E. Swales, Florence I. Raynaud, Michelle D. Garrett, Udai Banerji
Journal: Clinical Cancer Research
Series: Author Choice
Clin Cancer Res (2020) 26 (18): 4777–4784.
https://doi.org/10.1158/1078-0432.CCR-20-0700
Published: 15 September 2020
View articletitled, First-in-Human Study of AT13148, a Dual ROCK-AKT Inhibitor in Patients with Solid Tumors
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Includes: Supplementary data
Journal Articles

Telomerase Reverse Transcriptase Promoter Mutations Identify a Genomically Defined and Highly Aggressive Human Pleural Mesothelioma Subgroup

Christine Pirker, Agnes Bilecz, Michael Grusch, Thomas Mohr, Barbara Heidenreich, Viktoria Laszlo, Paul Stockhammer, Daniela Lötsch-Gojo, Johannes Gojo, Lisa Gabler, Sabine Spiegl-Kreinecker, Balazs Dome, Ariane Steindl, Thomas Klikovits, Mir Alireza Hoda, Marko Jakopovic, Miroslav Samarzija, Katja Mohorcic, Izidor Kern, Barbara Kiesel, Luka Brcic, Felicitas Oberndorfer, Leonhard Müllauer, Walter Klepetko, Wolfgang M. Schmidt, Rajiv Kumar, Balazs Hegedus, Walter Berger
Journal: Clinical Cancer Research
Clin Cancer Res (2020) 26 (14): 3819–3830.
https://doi.org/10.1158/1078-0432.CCR-19-3573
Published: 15 July 2020
View articletitled, Telomerase Reverse Transcriptase Promoter Mutations Identify a Genomically Defined and Highly Aggressive Human Pleural Mesothelioma Subgroup
Open the PDF for Telomerase Reverse Transcriptase Promoter Mutations Identify a Genomically Defined and Highly Aggressive Human Pleural Mesothelioma Subgroup in another window
Includes: Supplementary data
Journal Articles

Predominance of Central Memory T Cells with High T-Cell Receptor Repertoire Diversity is Associated with Response to PD-1/PD-L1 Inhibition in Merkel Cell Carcinoma

Ivelina Spassova, Selma Ugurel, Patrick Terheyden, Antje Sucker, Jessica C. Hassel, Cathrin Ritter, Linda Kubat, Daniel Habermann, Farnoush Farahpour, Mohammadkarim Saeedghalati, Lukas Peiffer, Rajiv Kumar, David Schrama, Daniel Hoffmann, Dirk Schadendorf, Jürgen C. Becker
Journal: Clinical Cancer Research
Clin Cancer Res (2020) 26 (9): 2257–2267.
https://doi.org/10.1158/1078-0432.CCR-19-2244
Published: 01 May 2020
View articletitled, Predominance of Central Memory T Cells with High T-Cell Receptor Repertoire Diversity is Associated with Response to PD-1/PD-L1 Inhibition in Merkel Cell Carcinoma
Open the PDF for Predominance of Central Memory T Cells with High T-Cell Receptor Repertoire Diversity is Associated with Response to PD-1/PD-L1 Inhibition in Merkel Cell Carcinoma in another window
Includes: Supplementary data
Journal Articles

Functional, Genetic, and Epigenetic Aspects of Base and Nucleotide Excision Repair in Colorectal Carcinomas

Jana Slyskova, Vlasta Korenkova, Andrew R. Collins, Pavel Prochazka, Ludmila Vodickova, Jiri Svec, Ludmila Lipska, Miroslav Levy, Michaela Schneiderova, Vaclav Liska, Lubos Holubec, Rajiv Kumar, Pavel Soucek, Alessio Naccarati, Pavel Vodicka
Journal: Clinical Cancer Research
Clin Cancer Res (2012) 18 (21): 5878–5887.
https://doi.org/10.1158/1078-0432.CCR-12-1380
Published: 06 November 2012
View articletitled, Functional, Genetic, and Epigenetic Aspects of Base and Nucleotide Excision Repair in Colorectal Carcinomas
Open the PDF for Functional, Genetic, and Epigenetic Aspects of Base and Nucleotide Excision Repair in Colorectal Carcinomas in another window
Includes: Supplementary data
Journal Articles

BRAF Mutations in Metastatic Melanoma: A Possible Association with Clinical Outcome

Rajiv Kumar, Sabrina Angelini, Kamila Czene, Ilari Sauroja, Marjo Hahka-Kemppinen, Seppo Pyrhönen, Kari Hemminki
Journal: Clinical Cancer Research
Clin Cancer Res (2003) 9 (9): 3362–3368.
Published: 05 September 2003
View articletitled, BRAF Mutations in Metastatic Melanoma: A Possible Association with Clinical Outcome
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Journal Articles

Detecting Homozygous Deletions in the CDKN2A(p16INK4a)/ARF(p14ARF ) Gene in Urinary Bladder Cancer Using Real-Time Quantitative PCR

Petra Berggren, Rajiv Kumar, Shigeru Sakano, Liina Hemminki, Takashi Wada, Gunnar Steineck, Jan Adolfsson, Per Larsson, Ulf Norming, Hans Wijkström, Kari Hemminki
Journal: Clinical Cancer Research
Clin Cancer Res (2003) 9 (1): 235–242.
Published: 01 January 2003
View articletitled, Detecting Homozygous Deletions in the CDKN2A(p16INK4a)/ARF(p14ARF ) Gene in Urinary Bladder Cancer Using Real-Time Quantitative PCR
Open the PDF for Detecting Homozygous Deletions in the CDKN2A(p16INK4a)/ARF(p14ARF ) Gene in Urinary Bladder Cancer Using Real-Time Quantitative PCR in another window