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Rahim Hirani
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Journal Articles

The Impact of PIK3R1 Mutations and Insulin–PI3K–Glycolytic Pathway Regulation in Prostate Cancer

Goutam Chakraborty, Subhiksha Nandakumar, Rahim Hirani, Bastien Nguyen, Konrad H. Stopsack, Christoph Kreitzer, Sai Harisha Rajanala, Romina Ghale, Ying Z. Mazzu, Naga Vara Kishore Pillarsetty, Gwo-Shu Mary Lee, Howard I. Scher, Michael J. Morris, Tiffany Traina, Pedram Razavi, Wassim Abida, Jeremy C. Durack, Stephen B. Solomon, Matthew G. Vander Heiden, Lorelei A. Mucci, Andreas G. Wibmer, Nikolaus Schultz, Philip W. Kantoff
Journal: Clinical Cancer Research
Clin Cancer Res (2022) 28 (16): 3603–3617.
https://doi.org/10.1158/1078-0432.CCR-21-4272
Published: 15 August 2022
View article titled, The Impact of PIK3R1 Mutations and Insulin–PI3K–Glycolytic Pathway Regulation in Prostate Cancer
Open the PDF for The Impact of PIK3R1 Mutations and Insulin–PI3K–Glycolytic Pathway Regulation in Prostate Cancer in another window
Includes: Supplementary data
Journal Articles

Attenuation of SRC Kinase Activity Augments PARP Inhibitor–mediated Synthetic Lethality in BRCA2-altered Prostate Tumors

Goutam Chakraborty, Nabeela Khan Patail, Rahim Hirani, Subhiksha Nandakumar, Ying Z. Mazzu, Yuki Yoshikawa, Mohammad Atiq, Lina E. Jehane, Konrad H. Stopsack, Gwo-Shu Mary Lee, Wassim Abida, Michael J. Morris, Lorelei A. Mucci, Daniel Danila, Philip W. Kantoff
Journal: Clinical Cancer Research
Clin Cancer Res (2021) 27 (6): 1792–1806.
https://doi.org/10.1158/1078-0432.CCR-20-2483
Published: 15 March 2021
View article titled, Attenuation of SRC Kinase Activity Augments PARP Inhibitor–mediated Synthetic Lethality in <em>BRCA2</em>-altered Prostate Tumors
Open the PDF for Attenuation of SRC Kinase Activity Augments PARP Inhibitor–mediated Synthetic Lethality in <em>BRCA2</em>-altered Prostate Tumors in another window
Includes: Supplementary data
Journal Articles

Significance of BRCA2 and RB1 Co-loss in Aggressive Prostate Cancer Progression

Goutam Chakraborty, Joshua Armenia, Ying Z. Mazzu, Subhiksha Nandakumar, Konrad H. Stopsack, Mohammad O. Atiq, Kazumasa Komura, Lina Jehane, Rahim Hirani, Kalyani Chadalavada, Yuki Yoshikawa, Nabeela A. Khan, Yu Chen, Wassim Abida, Lorelei A. Mucci, Gwo-Shu Mary Lee, Gouri J. Nanjangud, Philip W. Kantoff
Journal: Clinical Cancer Research
Clin Cancer Res (2020) 26 (8): 2047–2064.
https://doi.org/10.1158/1078-0432.CCR-19-1570
Published: 15 April 2020
View article titled, Significance of <em>BRCA2</em> and <em>RB1</em> Co-loss in Aggressive Prostate Cancer Progression
Open the PDF for Significance of <em>BRCA2</em> and <em>RB1</em> Co-loss in Aggressive Prostate Cancer Progression in another window
Includes: Supplementary data