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Quang-Dé Nguyen
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Journal Articles

Selective CDK7 Inhibition Suppresses Cell Cycle Progression and MYC Signaling While Enhancing Apoptosis in Therapy-resistant Estrogen Receptor–positive Breast Cancer

Cristina Guarducci, Agostina Nardone, Douglas Russo, Zsuzsanna Nagy, Capucine Heraud, Albert Grinshpun, Qi Zhang, Allegra Freelander, Mathew Joseph Leventhal, Avery Feit, Gabriella Cohen Feit, Ariel Feiglin, Weihan Liu, Francisco Hermida-Prado, Nikolas Kesten, Wen Ma, Carmine De Angelis, Antonio Morlando, Madison O'Donnell, Sergey Naumenko, Shixia Huang, Quang-Dé Nguyen, Ying Huang, Luca Malorni, Johann S. Bergholz, Jean J. Zhao, Ernest Fraenkel, Elgene Lim, Rachel Schiff, Geoffrey I. Shapiro, Rinath Jeselsohn
Journal: Clinical Cancer Research
Clin Cancer Res (2024) 30 (9): 1889–1905.
https://doi.org/10.1158/1078-0432.CCR-23-2975
Published: 01 May 2024
View article titled, Selective CDK7 Inhibition Suppresses Cell Cycle Progression and MYC Signaling While Enhancing Apoptosis in Therapy-resistant Estrogen Receptor–positive Breast Cancer
Open the PDF for Selective CDK7 Inhibition Suppresses Cell Cycle Progression and MYC Signaling While Enhancing Apoptosis in Therapy-resistant Estrogen Receptor–positive Breast Cancer in another window
Includes: Supplementary data
Journal Articles

Concurrent Dexamethasone Limits the Clinical Benefit of Immune Checkpoint Blockade in Glioblastoma

J. Bryan Iorgulescu, Prafulla C. Gokhale, Maria C. Speranza, Benjamin K. Eschle, Michael J. Poitras, Margaret K. Wilkens, Kara M. Soroko, Chhayheng Chhoeu, Aine Knott, Yan Gao, Mary Jane Lim-Fat, Gregory J. Baker, Dennis M. Bonal, Quang-Dé Nguyen, Gareth R. L. Grant, Keith L. Ligon, Peter K. Sorger, E. Antonio Chiocca, Ana C. Anderson, Paul T. Kirschmeier, Arlene H. Sharpe, Gordon J. Freeman, David A. Reardon
Journal: Clinical Cancer Research
Clin Cancer Res (2021) 27 (1): 276–287.
https://doi.org/10.1158/1078-0432.CCR-20-2291
Published: 04 January 2021
View article titled, Concurrent Dexamethasone Limits the Clinical Benefit of Immune Checkpoint Blockade in Glioblastoma
Open the PDF for Concurrent Dexamethasone Limits the Clinical Benefit of Immune Checkpoint Blockade in Glioblastoma in another window
Includes: Supplementary data
Journal Articles

Positron Emission Tomography Imaging with 18F-Labeled ZHER2:2891 Affibody for Detection of HER2 Expression and Pharmacodynamic Response to HER2-Modulating Therapies

Sebastian Trousil, Susan Hoppmann, Quang-Dé Nguyen, Maciej Kaliszczak, Giampaolo Tomasi, Peter Iveson, Duncan Hiscock, Eric O. Aboagye
Journal: Clinical Cancer Research
Clin Cancer Res (2014) 20 (6): 1632–1643.
https://doi.org/10.1158/1078-0432.CCR-13-2421
Published: 13 March 2014
View article titled, Positron Emission Tomography Imaging with <sup>18</sup>F-Labeled Z<em><sub>HER2:2891</sub></em> Affibody for Detection of HER2 Expression and Pharmacodynamic Response to HER2-Modulating Therapies
Open the PDF for Positron Emission Tomography Imaging with <sup>18</sup>F-Labeled Z<em><sub>HER2:2891</sub></em> Affibody for Detection of HER2 Expression and Pharmacodynamic Response to HER2-Modulating Therapies in another window
Includes: Supplementary data
Journal Articles

Temporal and Spatial Evolution of Therapy-Induced Tumor Apoptosis Detected by Caspase-3–Selective Molecular Imaging

Quang-Dé Nguyen, Ioannis Lavdas, James Gubbins, Graham Smith, Robin Fortt, Laurence S. Carroll, Martin A. Graham, Eric O. Aboagye
Journal: Clinical Cancer Research
Clin Cancer Res (2013) 19 (14): 3914–3924.
https://doi.org/10.1158/1078-0432.CCR-12-3814
Published: 15 July 2013
View article titled, Temporal and Spatial Evolution of Therapy-Induced Tumor Apoptosis Detected by Caspase-3–Selective Molecular Imaging
Open the PDF for Temporal and Spatial Evolution of Therapy-Induced Tumor Apoptosis Detected by Caspase-3–Selective Molecular Imaging in another window
Includes: Supplementary data
Journal Articles

Evaluation of Deuterated 18F- and 11C-Labeled Choline Analogs for Cancer Detection by Positron Emission Tomography

Timothy H. Witney, Israt S. Alam, David R. Turton, Graham Smith, Laurence Carroll, Diana Brickute, Frazer J. Twyman, Quang-Dé Nguyen, Giampaolo Tomasi, Ramla O. Awais, Eric O. Aboagye
Journal: Clinical Cancer Research
Clin Cancer Res (2012) 18 (4): 1063–1072.
https://doi.org/10.1158/1078-0432.CCR-11-2462
Published: 14 February 2012
View article titled, Evaluation of Deuterated <sup>18</sup>F- and <sup>11</sup>C-Labeled Choline Analogs for Cancer Detection by Positron Emission Tomography
Open the PDF for Evaluation of Deuterated <sup>18</sup>F- and <sup>11</sup>C-Labeled Choline Analogs for Cancer Detection by Positron Emission Tomography in another window
Includes: Supplementary data